Researcher profile · Semantic Scholar

H. E. Fleming

h-index: 23
Works: 38
Citations: 5,516

Most-cited papers

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a
V. Janzen, R. Forkert, H. E. Fleming, Y. Saito +6 more
2006Nature1,109 citations
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Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche
Cristina Lo Celso, H. E. Fleming, Juwell W. Wu, Cher X. Zhao +6 more
2008Nature937 citations Open access
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The effect of an anti-IgE monoclonal antibody on the early- and late-phase responses to allergen inhalation in asthmatic subjects.
John V. Fahy, H. E. Fleming, Hofer H. Wong, J. Liu +4 more
1997American Journal of Respiratory and Critical Care Medicine703 citations
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Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo.
H. E. Fleming, V. Janzen, Cristina Lo Celso, Jun Guo +3 more
2008Cell Stem Cell534 citations Open access
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Pluripotent Stem Cell-Derived Hepatocyte-Like Cells
R. Schwartz, H. E. Fleming, S. Khetani, S. Bhatia
2014Biotechnology Advances270 citations Open access
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Cytokine Signaling and Hematopoietic Homeostasis Are Disrupted in Lnk-deficient Mice
L. Velazquez, Alec M. Cheng, H. E. Fleming, C. Furlonger +4 more
2002Journal of Experimental Medicine242 citations Open access
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In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease
K. Stevens, M. Scull, V. Ramanan, Chelsea L. Fortin +14 more
2017Science Translational Medicine163 citations Open access
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Development of light-activated CRISPR using photocleavable protectors of guide RNAs
P. Jain, V. Ramanan, A. Schepers, Nisha Dalvie +3 more
2016Angewandte Chemie158 citations Open access
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Modulation of the IL-7 dose-response threshold during pro-B cell differentiation is dependent on pre-B cell receptor expression.
A. Marshall, H. E. Fleming, Gillian Wu, C. Paige
1998Journal of Immunology158 citations Open access
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Rhinovirus-16 colds in healthy and in asthmatic subjects: similar changes in upper and lower airways.
H. E. Fleming, F. Little, D. Schnurr, P. Avila +4 more
1999American Journal of Respiratory and Critical Care Medicine147 citations
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Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens
S. March, V. Ramanan, Kartik Trehan, Shengyong Ng +9 more
2015Nature Protocols136 citations Open access
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In vitro culture, drug sensitivity, and transcriptome of Plasmodium vivax hypnozoites
N. Gural, Liliana Mancio-Silva, Alex B. Miller, A. Galstian +10 more
2018Cell Host and Microbe130 citations Open access
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Hematopoietic stem cell responsiveness to exogenous signals is limited by caspase-3.
V. Janzen, H. E. Fleming, T. Riedt, Göran Karlsson +8 more
2008Cell Stem Cell130 citations Open access
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CRISPR-Cas-amplified urine biomarkers for multiplexed and portable cancer diagnostics
Liang-Liang Hao, Renee T. Zhao, Chayanon Ngambenjawong, Henry Ko +2 more
2020bioRxiv118 citations Open access
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Sensitivity of arabinosyladenine-resistant mutants of herpes simplex virus to other antiviral drugs and mapping of drug hypersensitivity mutations to the DNA polymerase locus
Donald M. Coen, H. E. Fleming, Laurel K. Leslie, Margaret J. Retondo
1985Journal of Virology112 citations Open access
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Noninvasive lung cancer detection via pulmonary protease profiling
Jesse D. Kirkpatrick, Andrew D. Warren, A. Soleimany, Peter M. K. Westcott +6 more
2020Science Translational Medicine77 citations Open access
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Cooperation between IL-7 and the pre-B cell receptor: a key to B cell selection.
H. E. Fleming, C. Paige
2002Seminars in Immunology76 citations
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Microenvironment-triggered multimodal precision diagnostics
Liang-Liang Hao, Nazanin Rohani, Renee T. Zhao, Emilia M. Pulver +6 more
2021Nature Materials59 citations
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Conditional Antimicrobial Peptide Therapeutics
Chayanon Ngambenjawong, Leslie W Chan, H. E. Fleming, S. Bhatia
2022ACS Nano55 citations Open access
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A single-cell liver atlas of Plasmodium vivax infection
Liliana Mancio-Silva, N. Gural, Eliana Real, M. Wadsworth +11 more
2022Cell Host and Microbe53 citations Open access
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CD45-Deficient Mice Accumulate Pro-B Cells Both In Vivo and In Vitro1
H. E. Fleming, C. D. Milne, C. Paige
2004Journal of Immunology30 citations Open access
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Non-viral delivery of CRISPR/Cas9 complex using CRISPR-GPS nanocomplexes
P. Jain, Justin H. Lo, Santosh R. Rananaware, Marco Downing +5 more
2019Nanoscale27 citations Open access
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Protease activity sensors noninvasively classify bacterial infections and antibiotic responses
Colin G. Buss, Jaideep S. Dudani, R. Akana, H. E. Fleming +1 more
2018EBioMedicine24 citations Open access
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Controlled Apoptosis of Stromal Cells to Engineer Human Microlivers
Amanda X. Chen, Arnav Chhabra, Hyun‐Ho Greco Song, H. E. Fleming +2 more
2020Advanced Functional Materials19 citations Open access
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Improving Drug Discovery by Nucleic Acid Delivery in Engineered Human Microlivers
Liliana Mancio-Silva, H. E. Fleming, Alex B. Miller, S. Milstein +4 more
2019Cell Metabolism16 citations Open access
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Virtual Undergraduate Research Experiences: More Than a Pandemic Stopgap
Tahoura S. Samad, H. E. Fleming, Sangeeta Bhatia
2021i Medicina10 citations Open access
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Herpes simplex virus mutants resistant to arabinosyladenine in the presence of deoxycoformycin
H. E. Fleming, Donald M. Coen
1984Antimicrobial Agents and Chemotherapy10 citations Open access
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Synthetic circuit-driven expression of heterologous enzymes for disease detection
Jiang He, Lior Nissim, A. Soleimany, Adina Binder-Nissim +3 more
2021ACS Synthetic Biology8 citations Open access
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Embryonic stem cells make human T cells
H. E. Fleming, D. Scadden
2006Proceedings of the National Academy of Sciences of the United States of America4 citations Open access
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Identification of NQO2 as a protein target in small molecule modulation of hepatocellular function
A. Schepers, Jing Shan, A. G. Cox, Ada Huang +5 more
2021ACS Chemical Biology3 citations Open access
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Gene signatures and host-parasite interactions revealed by dual single-cell profiling of Plasmodium vivax liver infection
Liliana Mancio-Silva, N. Gural, M. Wadsworth, Vincent L. Butty +10 more
2021bioRxiv2 citations Open access
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Tissue Engineering: Controlled Apoptosis of Stromal Cells to Engineer Human Microlivers (Adv. Funct. Mater. 48/2020)
Amanda X. Chen, Arnav Chhabra, Hyun‐Ho Greco Song, H. E. Fleming +2 more
20202 citations Open access
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702 The effect of treatment with a monoclonal antibody directed against IgE on allergic airway responses in asthmatic subjects
J. Fahy, H. E. Fleming, H. Wong, J. Liu +4 more
19962 citations
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Multifunctional Role of Caspase-3 in Regulating Hematopoietic Stem Cells.
V. Janzen, H. E. Fleming, Michael T. Waring, C. D. Milne +1 more
20061 citations
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Principles of Tissue Engineering
Amanda X. Chen, Arnav Chhabra, H. E. Fleming, S. Bhatia
20200 citations
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Caspase-3 Has Apoptotic and Non-Apoptotic Functions in Regulating the Fate of Hematopoietic Stem Cells.
V. Janzen, H. E. Fleming, G. Reynolds, Michael T. Waring +1 more
20050 citations
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Expression Is Dependent on Pre-B Cell Receptor Threshold During ProB Cell Differentiation Modulation of the IL-7 Dose-Response
A. Marshall, H. E. Fleming, Gillian Wu, C. Paige
19980 citations
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Development of light-activated CRISPR using photocleavable protectors of guide RNAs
P. Jain, V. Ramanan, A. Schepers, Nisha Dalvie +5 more
0 citations
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V. Ramanan

×4

Amanda X. Chen×4

S. March×4

N. Gural×4

Liliana Mancio-Silva×4

Michael T. Waring×3

Cristina Lo Celso×3

Christopher S. Chen×3