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V. Harmat · SciRah

Researcher profile · Semantic Scholar

V. Harmat

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V. Harmat — researcher profile on SciRah

h-index: 24
Works: 136
Citations: 1,718

Most-cited papers

MASP-1, a Promiscuous Complement Protease: Structure of Its Catalytic Region Reveals the Basis of Its Broad Specificity1
J. Dobó, V. Harmat, L. Beinrohr, E. Sebestyen +2 more
2009Journal of Immunology132 citations Open access
Semantic Scholar
C1 Inhibitor Serpin Domain Structure Reveals the Likely Mechanism of Heparin Potentiation and Conformational Disease*
L. Beinrohr, V. Harmat, J. Dobó, Zsolt Lörincz +2 more
2007Journal of Biological Chemistry97 citations Open access
Semantic Scholar
The structure of MBL-associated serine protease-2 reveals that identical substrate specificities of C1s and MASP-2 are realized through different sets of enzyme-substrate interactions.
V. Harmat, P. Gál, J. Kardos, K. Szilágyi +4 more
2004Journal of Molecular Biology92 citations
Semantic Scholar
Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2*
D. Heja, V. Harmat, K. Fodor, M. Wilmanns +5 more
2012Journal of Biological Chemistry90 citations Open access
Semantic Scholar
A True Autoactivating Enzyme
P. Gál, V. Harmat, A. Kocsis, T. Bian +7 more
2005Journal of Biological Chemistry81 citations Open access
Semantic Scholar
Directed Evolution Reveals the Binding Motif Preference of the LC8/DYNLL Hub Protein and Predicts Large Numbers of Novel Binders in the Human Proteome
P. Rapali, L. Radnai, Dániel Süveges, V. Harmat +5 more
2011PLoS ONE77 citations Open access
Semantic Scholar
Quantitative Characterization of the Activation Steps of Mannan-binding Lectin (MBL)-associated Serine Proteases (MASPs) Points to the Central Role of MASP-1 in the Initiation of the Complement Lectin Pathway*
Márton Megyeri, V. Harmat, B. Major, Á. Végh +8 more
2013Journal of Biological Chemistry68 citations Open access
Semantic Scholar
Aromatic stacking between nucleobase and enzyme promotes phosphate ester hydrolysis in dUTPase
Ildikó Pécsi, I. Leveles, V. Harmat, B. Vértessy +1 more
2010Nucleic Acids Research62 citations Open access
Semantic Scholar
Flexible segments modulate co-folding of dUTPase and nucleocapsid proteins
V. Németh-Pongrácz, O. Barabas, M. Fuxreiter, I. Simon +11 more
2006Nucleic Acids Research52 citations Open access
Semantic Scholar
Extended intermolecular interactions in a serine protease-canonical inhibitor complex account for strong and highly specific inhibition.
K. Fodor, V. Harmat, C. Hetényi, J. Kardos +5 more
2005Journal of Molecular Biology45 citations
Semantic Scholar
Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: structure of the active catalytic region of C1r.
J. Kardos, V. Harmat, A. Palló, O. Barabas +6 more
2008Molecular Immunology44 citations
Semantic Scholar
The acylaminoacyl peptidase from Aeropyrum pernix K1 thought to be an exopeptidase displays endopeptidase activity.
A. Kiss, B. Hornung, K. Rádi, Zsolt Gengeliczki +5 more
2007Journal of Molecular Biology44 citations
Semantic Scholar
Enzyme:substrate hydrogen bond shortening during the acylation phase of serine protease catalysis.
K. Fodor, V. Harmat, R. Neutze, L. Szilágyi +2 more
2006Biochemistry44 citations
Semantic Scholar
Structure and Catalysis of Acylaminoacyl Peptidase
V. Harmat, K. Domokos, D. Menyhárd, A. Palló +5 more
2010Journal of Biological Chemistry42 citations Open access
Semantic Scholar
Prolyl oligopeptidase inhibition by N-acyl-pro-pyrrolidine-type molecules.
K. Kánai, P. Arányi, Z. Böcskei, G. Ferenczy +5 more
2008Journal of Medicinal Chemistry32 citations Open access
Semantic Scholar
Structure and enzymatic mechanism of a moonlighting dUTPase.
I. Leveles, V. Németh, J. Szabó, V. Harmat +9 more
2013Acta Crystallographica Section D: Biological Crystallography31 citations Open access
Semantic Scholar
Purification, crystallization and preliminary X-ray analysis of human mannose-binding lectin-associated serine protease-1 (MASP-1) catalytic region.
J. Dobó, V. Harmat, E. Sebestyen, L. Beinrohr +2 more
2008Acta Crystallographica. Section F : Structural Biology and Crystallization Communications28 citations Open access
Semantic Scholar
1,3-Dipolar Cycloaddition of Isatin-Derived Azomethine Ylides with 2 H-Azirines: Stereoselective Synthesis of 1,3-Diazaspiro[bicyclo[3.1.0]hexane]oxindoles.
A. Angyal, András Demjén, V. Harmat, J. Wölfling +2 more
2019Journal of Organic Chemistry27 citations
Semantic Scholar
The Structure of the Complex of Calmodulin with KAR-2
I. Horvath, V. Harmat, A. Perczel, Villö K. Pálfi +5 more
2005Journal of Biological Chemistry27 citations Open access
Semantic Scholar
Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases
E. Takács, G. Nagy, I. Leveles, V. Harmat +3 more
2010FEBS Letters22 citations Open access
Semantic Scholar
Structural Evidence for Non-canonical Binding of Ca2+ to a Canonical EF-hand of a Conventional Myosin*
J. Debreczeni, L. Farkas, V. Harmat, C. Hetényi +4 more
2005Journal of Biological Chemistry22 citations Open access
Semantic Scholar
Structure Determination of the Transactivation Domain of p53 in Complex with S100A4 Using Annexin A2 as a Crystallization Chaperone.
Péter Ecsédi, G. Gógl, Henrietta Hóf, B. Kiss +2 more
2020Structure21 citations Open access
Semantic Scholar
A Self-compartmentalizing Hexamer Serine Protease from Pyrococcus Horikoshii
D. Menyhárd, A. Kiss-Szemán, É. Tichy-Rács, B. Hornung +7 more
2013Journal of Biological Chemistry21 citations Open access
Semantic Scholar
Characterization of a novel acylaminoacyl peptidase with hexameric structure and endopeptidase activity.
Z. Szeltner, A. Kiss, K. Domokos, V. Harmat +2 more
2009Biochimica et Biophysica Acta16 citations Open access
Semantic Scholar
Structures of calmodulin–melittin complexes show multiple binding modes lacking classical anchoring interactions
Z. Dürvanger, Tünde Juhász, K. Liliom, V. Harmat
2023Journal of Biological Chemistry15 citations Open access
Semantic Scholar
Synthesis, spectral- and theoretical study, x-ray analysis, and antiproliferative activity of 4,5-dihydrobenzoferroceno[1,2-d][1,2,3]selenadiazole and its benzo-fused analogue
T. Pasinszki, Dániel Dzsotján, Győző G. Lajgut, V. Harmat +3 more
201815 citations
Semantic Scholar
Structural and kinetic contributions of the oxyanion binding site to the catalytic activity of acylaminoacyl peptidase.
A. Kiss, A. Palló, G. Náray‐Szabó, V. Harmat +1 more
2008Journal of Structural Biology14 citations
Semantic Scholar
Thermally Induced Solid-Phase Quasi-Intramolecular Redox Reactions of [Hexakis(urea-O)iron(III)] Permanganate: An Easy Reaction Route to Prepare Potential (Fe,Mn)Ox Catalysts for CO2 Hydrogenation
K. Béres, Z. Homonnay, L. Kvítek, Z. Dürvanger +10 more
2022Inorganic Chemistry12 citations Open access
Semantic Scholar
Achieving Functionality Through Modular Build-Up: Structure and Size Selection of Serine Oligopeptidases.
A. Kiss-Szemán, V. Harmat, D. Menyhárd
2019Current protein and peptide science11 citations
Semantic Scholar
Cryo-EM structure of acylpeptide hydrolase reveals substrate selection by multimerization and a multi-state serine-protease triad
A. Kiss-Szemán, Pál Stráner, I. Jákli, N. Hosogi +3 more
2022Chemical Science10 citations Open access
Semantic Scholar
Structural Diversity in Calmodulin - Peptide Interactions.
Z. Dürvanger, V. Harmat
2019Current protein and peptide science10 citations Open access
Semantic Scholar
Structure and mechanism of calmodulin binding to a signaling sphingolipid reveal new aspects of lipid‐protein interactions
E. Kovács, V. Harmat, J. Tóth, B. Vértessy +3 more
2010The FASEB Journal10 citations Open access
Semantic Scholar
Dynamic disorder in the high-temperature polymorph of bis[diamminesilver(I)] sulfate—reasons and consequences of simultaneous ammonia release from two different polymorphs
Laura Bereczki, L. A. Fogaça, Z. Dürvanger, V. Harmat +8 more
2021Journal of coordination chemistry8 citations Open access
Semantic Scholar
Origin of problems related to Staudinger reduction in carbopeptoid syntheses
Barbara Csordás, Adrienn Nagy, V. Harmat, V. Zsoldos-Mády +4 more
2016Amino Acids8 citations Open access
Semantic Scholar
Catalytically distinct states captured in a crystal lattice: the substrate-bound and scavenger states of acylaminoacyl peptidase and their implications for functionality.
D. Menyhárd, Z. Orgován, Z. Szeltner, I. Szamosi +1 more
2015Acta Crystallographica Section D: Biological Crystallography8 citations Open access
Semantic Scholar
Comparison of ligand binding and conformational stability of human calmodulin with its homolog from the malaria parasite Plasmodium falciparum
Tünde Juhász, J. Kardos, Z. Dürvanger, V. Harmat +1 more
2020FASEB bioAdvances7 citations Open access
Semantic Scholar
Radiation-damage investigation of a DNA 16-mer.
V. Bugris, V. Harmat, G. Ferenc, S. Brockhauser +2 more
2019Journal of Synchrotron Radiation7 citations Open access
Semantic Scholar
Approaches to Pyranuronic β‐Sugar Amino Acid Building Blocks of Peptidosaccharide Foldamers
Viktória Goldschmidt Gőz, I. Pintér, V. Harmat, A. Perczel
20187 citations Open access
Semantic Scholar
Crystallization and preliminary crystallographic analysis of dUTPase from the φ11 helper phage of Staphylococcus aureus.
I. Leveles, G. Róna, I. Zagyva, Á. Bendes +2 more
2011Acta Crystallographica. Section F : Structural Biology and Crystallization Communications7 citations Open access
Semantic Scholar
Surprisingly great difference in reactivity depending upon the ring size: Solvolysis and molecular structure study of some N-trimethylsilylated cyclic ureas
R. Szalay, G. Pongor, V. Harmat, Z. Böcskei +1 more
20057 citations
Semantic Scholar
Theoretical Aspects of Molecular Recognition
V. Harmat, G. Náray‐Szabó
20096 citations
Semantic Scholar
Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation
Z. Nagy, D. Heja, D. Bencze, B. Kiss +9 more
2022Journal of Biological Chemistry4 citations Open access
Semantic Scholar
Configuration controlled crystal and/or gel formation of protected D-Glucosamines supported by promiscuous interaction surfaces and a conformationally heterogeneous solution state.
Anita Kapros, Attila Balázs, V. Harmat, A. Háló +4 more
2020Chemistry4 citations
Semantic Scholar
A carbapenem antibiotic inhibiting a mammalian serine protease: structure of the acylaminoacyl peptidase–meropenem complex
A. Kiss-Szemán, Luca Takács, Z. Orgován, Pál Stráner +6 more
2022Chemical Science3 citations Open access
Semantic Scholar
Novel Polycondensed Partly Saturated β-Carbolines Including Ferrocene Derivatives: Synthesis, DFT-Supported Structural Analysis, Mechanism of Some Diastereoselective Transformations and a Preliminary Study of their In Vitro Antiproliferative Effects
K. Fodor, Dániel Hutai, Tamás Jernei, Angéla Takács +8 more
2020Molecules3 citations Open access
Semantic Scholar
Directed Evolution-Driven Increase of Structural Plasticity Is a Prerequisite for Binding the Complement Lectin Pathway Blocking MASP-Inhibitor Peptides
Z. Dürvanger, E. Boros, Z. Nagy, Rózsa Hegedüs +11 more
2022ACS Chemical Biology2 citations Open access
Semantic Scholar
Correction: Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation.
Z. A. Nagy, D. Heja, D. Bencze, B. Kiss +9 more
2022Journal of Biological Chemistry1 citations Open access
Semantic Scholar
Strong influence of intramolecular Si...O proximity on reactivity: Systematic molecular structure, solvolysis, and mechanistic study of cyclic N-trimethylsilyl carboxamide derivatives
R. Szalay, V. Harmat, János Eőri, G. Pongor
20171 citations
Semantic Scholar
Probing calmodulin - peptide interactions of different species with the same target peptide
Z. Dürvanger, Tünde Juhász, K. Liliom, V. Harmat
20161 citations Open access
Semantic Scholar
New Aspects of Lipid-Protein Interactions Revealed by Calmodulin Binding to the Lipid Mediator Sphingosylphosphorylcholine
E. Kovács, V. Harmat, J. Tóth, B. Vértessy +3 more
20101 citations Open access
Semantic Scholar

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