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I. Mitroulis · SciRah

Researcher profile · Semantic Scholar

I. Mitroulis

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I. Mitroulis — researcher profile on SciRah

h-index: 46
Works: 152
Citations: 15K

Most-cited papers

Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity
I. Mitroulis, Klara Ruppova, Bao-Mei Wang, Lan-Sun Chen +24 more
2018Cell1,002 citations Open access
Semantic Scholar
Complement and tissue factor-enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis
P. Skendros, Alexandros Mitsios, A. Chrysanthopoulou, D. Mastellos +13 more
2020medRxiv706 citations Open access
Semantic Scholar
Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity
Lydia Kalafati, I. Kourtzelis, J. Schulte-Schrepping, Xiaofei Li +26 more
2020Cell535 citations Open access
Semantic Scholar
To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps
Sebastian Boeltz, Poorya Amini, H. Anders, F. Andrade +45 more
2019Cell Death and Differentiation411 citations Open access
Semantic Scholar
Maladaptive innate immune training of myelopoiesis links inflammatory comorbidities
Xiaofei Li, Hui Wang, Xiang-Sheng Yu, Gundappa Saha +6 more
2022Cell300 citations Open access
Semantic Scholar
Patients with COVID-19: in the dark-NETs of neutrophils
M. Ackermann, H. Anders, R. Bilyy, G. Bowlin +43 more
2021Cell Death and Differentiation277 citations Open access
Semantic Scholar
Hematopoietic progenitor cells as integrative hubs for adaptation to and fine-tuning of inflammation
T. Chavakis, I. Mitroulis, G. Hajishengallis
2019Nature Immunology270 citations Open access
Semantic Scholar
DEL-1 promotes macrophage efferocytosis and clearance of inflammation
I. Kourtzelis, Xiaofei Li, I. Mitroulis, Daniel Grosser +23 more
2018Nature Immunology270 citations Open access
Semantic Scholar
A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity
K. Chung, A. Chatzigeorgiou, M. Economopoulou, Rubén García-Martín +13 more
2017Nature Immunology160 citations Open access
Semantic Scholar
Tumor-Associated Macrophages in Hepatocellular Carcinoma Pathogenesis, Prognosis and Therapy
Konstantinos Arvanitakis, T. Koletsa, I. Mitroulis, Georgios S. Germanidis
2022Cancers121 citations Open access
Semantic Scholar
REDD1/Autophagy Pathway Is Associated with Neutrophil-Driven IL-1β Inflammatory Response in Active Ulcerative Colitis
Iliana Angelidou, A. Chrysanthopoulou, Alexandros Mitsios, S. Arelaki +11 more
2018Journal of Immunology120 citations Open access
Semantic Scholar
Autophagy in Neutrophils: From Granulopoiesis to Neutrophil Extracellular Traps
P. Skendros, I. Mitroulis, K. Ritis
2018Front. Cell Dev. Biol.119 citations Open access
Semantic Scholar
Immunometabolic Crosstalk: An Ancestral Principle of Trained Immunity?
S. Penkov, I. Mitroulis, G. Hajishengallis, T. Chavakis
2018Trends in immunology114 citations Open access
Semantic Scholar
Regulation of the Bone Marrow Niche by Inflammation
I. Mitroulis, Lydia Kalafati, M. Bornhäuser, G. Hajishengallis +1 more
2020Frontiers in Immunology110 citations Open access
Semantic Scholar
Tumor-Associated Neutrophils in Hepatocellular Carcinoma Pathogenesis, Prognosis, and Therapy
Konstantinos Arvanitakis, I. Mitroulis, Georgios S. Germanidis
2021Cancers109 citations Open access
Semantic Scholar
From leukocyte recruitment to resolution of inflammation: the cardinal role of integrins
I. Kourtzelis, I. Mitroulis, Janusz V. Renesse, G. Hajishengallis +1 more
2017Journal of Leukocyte Biology100 citations Open access
Semantic Scholar
Interferon lambda1/IL‐29 and inorganic polyphosphate are novel regulators of neutrophil‐driven thromboinflammation
A. Chrysanthopoulou, K. Kambas, D. Stakos, I. Mitroulis +13 more
2017Journal of Pathology93 citations
Semantic Scholar
Secreted protein Del-1 regulates myelopoiesis in the hematopoietic stem cell niche.
I. Mitroulis, Lan-Sun Chen, R. Singh, I. Kourtzelis +20 more
2017Journal of Clinical Investigation85 citations Open access
Semantic Scholar
Transcriptome reprogramming and myeloid skewing in haematopoietic stem and progenitor cells in systemic lupus erythematosus
M. Grigoriou, A. Banos, A. Filia, P. Pavlidis +8 more
2019Annals of the Rheumatic Diseases81 citations Open access
Semantic Scholar
NETopathies? Unraveling the Dark Side of Old Diseases through Neutrophils
Alexandros Mitsios, Athanasios Arampatzioglou, S. Arelaki, I. Mitroulis +1 more
2017Frontiers in Immunology76 citations Open access
Semantic Scholar
Regulated in development and DNA damage responses 1 (REDD1) links stress with IL‐1&bgr;–mediated familial Mediterranean fever attack through autophagy‐driven neutrophil extracellular traps
P. Skendros, A. Chrysanthopoulou, F. Rousset, K. Kambas +18 more
2017Journal of Allergy and Clinical Immunology73 citations Open access
Semantic Scholar
Myelopoiesis in the context of innate immunity
I. Mitroulis, Lydia Kalafati, G. Hajishengallis, T. Chavakis
2018Journal of Innate Immunity65 citations Open access
Semantic Scholar
Linking Complement Activation, Coagulation, and Neutrophils in Transplant-Associated Thrombotic Microangiopathy
E. Gavriilaki, A. Chrysanthopoulou, I. Sakellari, I. Batsis +9 more
2019Thrombosis and Haemostasis62 citations
Semantic Scholar
Complement C3 inhibition in severe COVID-19 using compstatin AMY-101
P. Skendros, Georgios S. Germanidis, D. Mastellos, C. Antoniadou +31 more
2022Science Advances51 citations Open access
Semantic Scholar
Endothelial-Specific Deficiency of ATG5 (Autophagy Protein 5) Attenuates Ischemia-Related Angiogenesis.
David Sprott, D. Poitz, I. Korovina, A. Ziogas +6 more
2019Arteriosclerosis, Thrombosis and Vascular Biology45 citations Open access
Semantic Scholar
Neutrophils as Orchestrators in Tumor Development and Metastasis Formation
Lydia Kalafati, I. Mitroulis, P. Verginis, T. Chavakis +1 more
2020Frontiers in Oncology42 citations Open access
Semantic Scholar
TRAINED INNATE IMMUNITY AND ITS IMPLICATIONS FOR MUCOSAL IMMUNITY AND INFLAMMATION
G. Hajishengallis, Xiaofei Li, I. Mitroulis, T. Chavakis
2019Advances in Experimental Medicine and Biology41 citations Open access
Semantic Scholar
Nerve growth factor regulates endothelial cell survival and pathological retinal angiogenesis
M. Troullinaki, V. Alexaki, I. Mitroulis, A. Witt +4 more
2019Journal of Cellular and Molecular Medicine34 citations Open access
Semantic Scholar
Bone marrow inflammatory memory in cardiometabolic disease and inflammatory comorbidities
I. Mitroulis, G. Hajishengallis, T. Chavakis
2023Cardiovascular Research33 citations Open access
Semantic Scholar
Autoinflammation: Lessons from the study of familial Mediterranean fever.
P. Skendros, C. Papagoras, I. Mitroulis, K. Ritis
2019Journal of Autoimmunity31 citations
Semantic Scholar
Combined administration of inhaled DNase, baricitinib and tocilizumab as rescue treatment in COVID-19 patients with severe respiratory failure
E. Gavriilidis, C. Antoniadou, A. Chrysanthopoulou, Maria Ntinopoulou +15 more
2022medRxiv24 citations Open access
Semantic Scholar
West Nile Disease Symptoms and Comorbidities: A Systematic Review and Analysis of Cases
Maria Bampali, K. Konstantinidis, Emmanouil E. Kellis, Theodoti Pouni +5 more
2022Tropical Medicine and Infectious Disease21 citations Open access
Semantic Scholar
CD147 is a Novel Interaction Partner of Integrin αMβ2 Mediating Leukocyte and Platelet Adhesion
D. Heinzmann, Moritz Noethel, S. V. von Ungern-Sternberg, I. Mitroulis +4 more
2020Biomolecules21 citations Open access
Semantic Scholar
Endothelial Injury Following CAR-T Cell Immunotherapy for Hematological Malignancies
C. Demosthenous, P. Evangelidis, Athanasios Gatsis, I. Mitroulis +5 more
2025Cancers20 citations
Semantic Scholar
ATVB IN FOCUS: Trained Immunity and Vascular Disease
I. Mitroulis, G. Hajishengallis, T. Chavakis
202020 citations
Semantic Scholar
The Liver Cancer Immune Microenvironment: Emerging Concepts for Myeloid Cell Profiling with Diagnostic and Therapeutic Implications
Konstantinos Arvanitakis, I. Mitroulis, A. Chatzigeorgiou, I. Elefsiniotis +1 more
2023Cancers19 citations Open access
Semantic Scholar
A gene expression map of host immune response in human brucellosis
I. Mitroulis, A. Chrysanthopoulou, G. Divolis, C. Ioannidis +16 more
2022Frontiers in Immunology19 citations Open access
Semantic Scholar
Endothelial cell-specific overexpression of Del-1 drives expansion of hematopoietic progenitor cells in the bone marrow
Lan-Sun Chen, I. Kourtzelis, R. Singh, S. Grossklaus +4 more
2018Thrombosis and Haemostasis19 citations Open access
Semantic Scholar
Increased Neutrophil Extracellular Traps Related to Smoking Intensity and Subclinical Atherosclerosis in Patients with Type 2 Diabetes
A. Chatzigeorgiou, I. Mitroulis, A. Chrysanthopoulou, Aigli-Ioanna Legaki +5 more
2020Thrombosis and Haemostasis16 citations Open access
Semantic Scholar
Neutrophil extracellular traps contribute to the development of hepatocellular carcinoma in NASH by promoting Treg differentiation.
Rallia-Iliana Velliou, I. Mitroulis, A. Chatzigeorgiou
2021Hepatobiliary surgery and nutrition15 citations Open access
Semantic Scholar
Enhanced medullary and extramedullary granulopoiesis sustain the inflammatory response in lupus nephritis
Eleni Zervopoulou, M. Grigoriou, S. Doumas, Danae Yiannakou +8 more
2024Lupus Science and Medicine13 citations Open access
Semantic Scholar
Serum granulocyte-macrophage colony-stimulating factor (GM-CSF) is increased in patients with active radiographic axial spondyloarthritis and persists despite anti-TNF treatment
C. Papagoras, S. Tsiami, A. Chrysanthopoulou, I. Mitroulis +1 more
2022Arthritis Research & Therapy12 citations Open access
Semantic Scholar
Levels of Produced Antibodies after Vaccination with mRNA Vaccine; Effect of Previous Infection with SARS-CoV-2
Theocharis G. Konstantinidis, S. Zisaki, I. Mitroulis, Eleni I. Konstantinidou +9 more
2021medRxiv10 citations Open access
Semantic Scholar
Modulation of IL-6/STAT3 signaling axis in CD4+FOXP3- T cells represents a potential antitumor mechanism of azacitidine.
E. Lamprianidou, C. Kordella, A. Kazachenka, E. Zoulia +16 more
2021Blood Advances10 citations Open access
Semantic Scholar
Single-cell transcriptomic analysis of hematopoietic progenitor cells from patients with systemic lupus erythematosus reveals interferon-inducible reprogramming in early progenitors
A. Filia, I. Mitroulis, C. Loukogiannaki, M. Grigoriou +7 more
2024Frontiers in Immunology9 citations Open access
Semantic Scholar
Single-Cell Analysis of Bone Marrow CD8+ T Cells in Myeloid Neoplasms Reveals Pathways Associated with Disease Progression and Response to Treatment with Azacitidine
Athanasios Tasis, N. Papaioannou, M. Grigoriou, N. Paschalidis +18 more
2024Cancer Research Communications8 citations Open access
Semantic Scholar
Patrolling human SLE haematopoietic progenitors demonstrate enhanced extramedullary colonisation; implications for peripheral tissue injury
I. Kokkinopoulos, A. Banos, M. Grigoriou, A. Filia +6 more
2021Scientific Reports7 citations Open access
Semantic Scholar
JAM-C Expression as a Biomarker to Predict Outcome of Patients with Acute Myeloid Leukemia-Letter.
M. von Bonin, Katharina Moll, M. Kramer, U. Oelschlägel +8 more
2018Cancer Research6 citations Open access
Semantic Scholar
Decreased Levels of Soluble Developmental Endothelial Locus-1 Are Associated with Thrombotic Microangiopathy in Pregnancy
G. Romanidou, Theocharis G. Konstantinidis, A. Natsi, K. Kantartzi +8 more
2022medRxiv5 citations Open access
Semantic Scholar
53BP1 Deficiency Promotes Pathological Neovascularization in Proliferative Retinopathy
M. Troullinaki, Rubén García-Martín, David Sprott, Anne Klotzsche-von Ameln +4 more
2019Thrombosis and Haemostasis5 citations
Semantic Scholar

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