F. Ruffinatti

Most-cited papers

1. Magnetic Iron Oxide Nanoparticles: Synthesis, Characterization and Functionalization for Biomedical Applications in the Central Nervous System

   S. Ansari, Eleonora Ficiarà, F. Ruffinatti, I. Stura +5 more

   2019Materials223 citations Open access

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2. Magnetic Nanoparticles in the Central Nervous System: Targeting Principles, Applications and Safety Issues

   F. D'Agata, F. Ruffinatti, S. Boschi, I. Stura +4 more

   2017Molecules95 citations Open access

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3. Susceptibility of different mouse strains to oxaliplatin peripheral neurotoxicity: Phenotypic and genotypic insights

   P. Marmiroli, B. Riva, E. Pozzi, E. Ballarini +13 more

   2017PLoS ONE70 citations Open access

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4. Proteomic analysis links alterations of bioenergetics, mitochondria-ER interactions and proteostasis in hippocampal astrocytes from 3xTg-AD mice

   Giulia Dematteis, Gabrielė Vydmantaitė, F. Ruffinatti, Malak Chahin +14 more

   2020Cell Death and Disease68 citations Open access

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5. Dysregulation of VEGF-induced proangiogenic Ca2+ oscillations in primary myelofibrosis-derived endothelial colony-forming cells.

   S. Dragoni, M. Reforgiato, Estella Zuccolo, Valentina Poletto +7 more

   2015Experimental Hematology55 citations Open access

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6. VEGF-induced intracellular Ca2+ oscillations are down-regulated and do not stimulate angiogenesis in breast cancer-derived endothelial colony forming cells

   F. Lodola, U. Laforenza, F. Cattaneo, F. Ruffinatti +10 more

   2017OncoTarget48 citations Open access

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7. SiO2 nanoparticles modulate the electrical activity of neuroendocrine cells without exerting genomic effects

   C. Distasi, F. Ruffinatti, M. Dionisi, S. Antoniotti +12 more

   2018Scientific Reports40 citations Open access

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8. Interaction of SiO2 nanoparticles with neuronal cells: Ionic mechanisms involved in the perturbation of calcium homeostasis.

   A. Gilardino, Federico Catalano, F. Ruffinatti, Gabriele Alberto +4 more

   2015International Journal of Biochemistry and Cell Biology36 citations Open access

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9. Gene expression, proteome and calcium signaling alterations in immortalized hippocampal astrocytes from an Alzheimer’s disease mouse model

   F. Rocchio, L. Tapella, M. Manfredi, M. Chisari +9 more

   2019Cell Death and Disease30 citations Open access

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10. Deletion of calcineurin from GFAP-expressing astrocytes impairs excitability of cerebellar and hippocampal neurons through astroglial Na+/K+ ATPase

    L. Tapella, T. Soda, L. Mapelli, Valeria Bortolotto +13 more

    2019bioRxiv28 citations Open access

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11. Absinthin, an agonist of the bitter taste receptor hTAS2R46, uncovers an ER-to-mitochondria Ca2+–shuttling event

    Maria Talmon, S. Rossi, D. Lim, F. Pollastro +6 more

    2019Journal of Biological Chemistry28 citations Open access

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12. Intracellular Ca²⁺ Signals to Reconstruct A Broken Heart: Still A Theoretical Approach?

    F. Moccia, F. Ruffinatti, Estella Zuccolo

    2015Current Drug Targets28 citations

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13. A luminal EF-hand mutation in STIM1 in mice causes the clinical hallmarks of tubular aggregate myopathy

    Celia Cordero-Sánchez, B. Riva, S. Reano, N. Clemente +11 more

    2019Disease Models & Mechanisms24 citations Open access

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14. Nanoparticles and potential neurotoxicity: focus on molecular mechanisms

    D. Lovisolo, M. Dionisi, F. Ruffinatti, C. Distasi

    201824 citations Open access

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15. Calcium signals: analysis in time and frequency domains.

    F. Ruffinatti, D. Lovisolo, C. Distasi, P. Ariano +2 more

    2011Journal of Neuroscience Methods19 citations Open access

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16. Isolation and Characterization of Buccal Fat Pad and Dental Pulp MSCs from the Same Donor

    T. Genova, D. Cavagnetto, Fabio Tasinato, S. Petrillo +6 more

    2021Biomedicines17 citations Open access

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17. Transcriptional Remodeling in Primary Hippocampal Astrocytes from an Alzheimer's Disease Mouse Model.

    F. Ruffinatti, L. Tapella, I. Gregnanin, A. Stevano +5 more

    2018Current Alzheimer Research17 citations Open access

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18. TRPM8-Rap1A Interaction Sites as Critical Determinants for Adhesion and Migration of Prostate and Other Epithelial Cancer Cells

    G. Chinigò, G. Grolez, M. Audero, A. Bokhobza +12 more

    2022Cancers15 citations Open access

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19. The interaction of SiO2 nanoparticles with the neuronal cell membrane: activation of ionic channels and calcium influx.

    C. Distasi, M. Dionisi, F. Ruffinatti, A. Gilardino +7 more

    2019Nanomedicine15 citations Open access

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20. When Neurons Encounter Nanoobjects: Spotlight on Calcium Signalling

    D. Lovisolo, A. Gilardino, F. Ruffinatti

    2014International Journal of Environmental Research and Public Health15 citations Open access

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21. Spatial Wavelet Analysis of Calcium Oscillations in Developing Neurons

    F. Ruffinatti, A. Gilardino, D. Lovisolo, M. Ferraro

    2013PLoS ONE14 citations Open access

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22. Calcium signals and FGF-2 induced neurite growth in cultured parasympathetic neurons: spatial localization and mechanisms of activation

    P. Zamburlin, F. Ruffinatti, A. Gilardino, S. Farcito +2 more

    2013Pflügers Archiv: European Journal of Physiology13 citations Open access

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23. Acidic Growth Conditions Promote Epithelial-to-Mesenchymal Transition to Select More Aggressive PDAC Cell Phenotypes In Vitro

    M. Audero, T. M. A. Carvalho, F. Ruffinatti, Thorsten Loeck +11 more

    2023Cancers12 citations Open access

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24. Mechanical and Biological Characterization of PMMA/Al2O3 Composites for Dental Implant Abutments

    I. Roato, T. Genova, D. Duraccio, F. Ruffinatti +10 more

    2023Polymers11 citations Open access

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25. CIC-39Na reverses the thrombocytopenia that characterizes tubular aggregate myopathy

    Celia Cordero-Sánchez, Emanuela Pessolano, B. Riva, Mauro Vismara +15 more

    2022Blood Advances11 citations Open access

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26. Deletion of calcineurin from astrocytes reproduces proteome signature of Alzheimer’s disease and epilepsy and predisposes to seizures

    L. Tapella, Giulia Dematteis, F. Ruffinatti, L. Ponzoni +16 more

    2020bioRxiv11 citations Open access

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27. Bisphenol A Activates Calcium Influx in Immortalized GnRH Neurons

    F. Ruffinatti, A. Gilardino, V. Secchi, E. Cottone +2 more

    2019International Journal of Molecular Sciences11 citations Open access

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28. Tumor Microenvironment Modulates Invadopodia Activity of Non-Selected and Acid-Selected Pancreatic Cancer Cells and Its Sensitivity to Gemcitabine and C18-Gemcitabine

    T. M. A. Carvalho, M. Audero, M. R. Greco, Marilena Ardone +10 more

    2024Cells9 citations Open access

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29. MORPHEUS: An automated tool for unbiased and reproducible cell morphometry

    F. Ruffinatti, T. Genova, F. Mussano, L. Munaron

    2020Journal of Cellular Physiology8 citations Open access

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30. Correction: Gene expression, proteome and calcium signaling alterations in immortalized hippocampal astrocytes from an Alzheimer’s disease mouse model

    F. Rocchio, L. Tapella, M. Manfredi, M. Chisari +9 more

    2019Cell Death and Disease8 citations Open access

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31. The emerging concept of transportome: state of the art.

    F. Ruffinatti, Giorgia Scarpellino, G. Chinigò, Luca Visentin +1 more

    2023Physiology7 citations Open access

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32. Transcriptomic profile comparison of monocytes from rheumatoid arthritis patients in treatment with methotrexate, anti-TNFa, abatacept or tocilizumab

    Maria Talmon, Marcella Percio, J. Obeng, F. Ruffinatti +6 more

    2023PLoS ONE7 citations Open access

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33. Osteoblast Response to Widely Ranged Texturing Conditions Obtained through High Power Laser Beams on Ti Surfaces

    F. Ruffinatti, T. Genova, I. Roato, Martina Perin +10 more

    2024Journal of Functional Biomaterials6 citations Open access

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34. Assessment of a Silicon-Photomultiplier-Based Platform for the Measurement of Intracellular Calcium Dynamics with Targeted Aequorin

    F. Ruffinatti, S. Lomazzi, L. Nardo, R. Santoro +7 more

    2020ACS Sensors6 citations Open access

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35. A biodegradable, microstructured, electroconductive and nano-integrated drug eluting patch (MENDEP) for myocardial tissue engineering

    C. Cristallini, Daniela Rossin, Roberto Vanni, N. Barbani +20 more

    2025Bioactive Materials5 citations Open access

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36. BioTEA: Containerized Methods of Analysis for Microarray-Based Transcriptomics Data

    Luca Visentin, Giorgia Scarpellino, G. Chinigò, L. Munaron +1 more

    2022bioRxiv5 citations Open access

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37. Early Stimulation of TREK Channel Transcription and Activity Induced by Oxaliplatin-Dependent Cytosolic Acidification

    M. Dionisi, F. Ruffinatti, B. Riva, D. Lim +9 more

    2020International Journal of Molecular Sciences5 citations Open access

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38. Assessment of the potential of SiPM-based systems for bioluminescence detection

    Samuela Lomazzi, M. Caccia, C. Distasi, Marianna Dionisi +5 more

    2019Nuclear Instruments and Methods in Physics Research Section A : Accelerators, Spectrometers, Detectors and Associated Equipment5 citations Open access

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39. REST levels affect the functional expression of voltage dependent calcium channels and the migratory activity in immortalized GnRH neurons.

    S. Antoniotti, F. Ruffinatti, Simona Torriano, A. Luganini +2 more

    2016Neuroscience Letters5 citations Open access

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40. The fallacy of functional nomenclature in the kingdom of biological multifunctionality: physiological and evolutionary considerations on ion channels

    L. Munaron, G. Chinigò, Giorgia Scarpellino, F. Ruffinatti

    2023Journal of Physiology4 citations Open access

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41. Calcium signals induced by FGF-2 in parasympathetic neurons: role of second messenger pathways.

    Pollyanna Zamburlin, F. Ruffinatti, A. Gilardino, S. Farcito +1 more

    2012Neuroscience Letters4 citations Open access

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42. The Transcriptional Landscape of BRAF Wild Type Metastatic Melanoma: A Pilot Study

    E. Lastraioli, F. Ruffinatti, G. Bagni, Luca Visentin +3 more

    2022International Journal of Molecular Sciences3 citations Open access

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43. The potential of TRP channels as new prognostic and therapeutic targets against prostate cancer progression.

    G. Chinigò, F. Ruffinatti, Luca Munaron

    2024Biochimica et biophysica acta. Reviews on cancer2 citations Open access

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44. A Transcriptomic Approach Reveals Selective Ribosomal Remodelling in the Tumour Versus the Stromal Compartment of Metastatic Colorectal Cancer

    E. Lastraioli, F. Ruffinatti, F. di Costanzo, C. Sala +2 more

    2021Cancers2 citations Open access

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45. The Pervasive Negative Regulation of Ion Channel Functional Families Across Human Cancers.

    Luca Visentin, Luca Munaron, P. Cassoni, L. Bertero +3 more

    2026American Journal of Physiology - Cell Physiology1 citations Open access

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46. The ion transport, GPCR, and RTK toolkit expression in the human cerebrovascular endothelial cell line, hCMEC/D3: an Omics perspective

    Giorgia Scarpellino, V. Brunetti, Francesca Scolari, Luca Visentin +3 more

    2025Frontiers in Physiology1 citations Open access

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47. Modulation of purinergic signaling in endothelial cells by tumor microenvironment.

    G. Chinigò, Giorgia Scarpellino, Sara Petrillo, T. Genova +2 more

    2024Vascular pharmacology1 citations

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48. Structuring data analysis projects in the Open Science era with Kerblam!

    Luca Visentin, Luca Munaron, F. Ruffinatti

    2024F1000Research1 citations Open access

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49. The Pervasive Negative Regulation of Ion Channel Functional Families Across Human Cancers

    Luca Visentin, Luca Munaron, P. Cassoni, L. Bertero +3 more

    2025bioRxiv0 citations Open access

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50. Corrigendum to “Transcriptomic data of Bevacizumab-adapted colorectal adenocarcinoma cells HCT-116” [Data In Brief, Volume 48, (Available online 17 March 2023) 1-9/Article 109069]

    C. Sala, T. Lottini, E. Lastraioli, F. Ruffinatti +2 more

    2023Data in Brief0 citations Open access

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