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T. Lottini · SciRah

Researcher profile · Semantic Scholar

T. Lottini

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T. Lottini — researcher profile on SciRah

h-index: 13
Works: 30
Citations: 613

Most-cited papers

Mitochondrial oxidative metabolism contributes to a cancer stem cell phenotype in cholangiocarcinoma.
C. Raggi, M. Taddei, E. Sacco, N. Navari +21 more
2021Journal of Hepatology153 citations Open access
Semantic Scholar
SHMT2-mediated mitochondrial serine metabolism drives 5-FU resistance by fueling nucleotide biosynthesis.
E. Pranzini, Elisa Pardella, L. Muccillo, Angela Leo +16 more
2022Cell Reports95 citations Open access
Semantic Scholar
Acute kidney injury promotes development of papillary renal cell adenoma and carcinoma from renal progenitor cells
A. Peired, Giulia Antonelli, M. Angelotti, M. Allinovi +33 more
2020Science Translational Medicine72 citations Open access
Semantic Scholar
Clarithromycin inhibits autophagy in colorectal cancer by regulating the hERG1 potassium channel interaction with PI3K
G. Petroni, G. Bagni, J. Iorio, Claudia Duranti +5 more
2020Cell Death and Disease51 citations Open access
Semantic Scholar
hERG1 Potassium Channels: Novel Biomarkers in Human Solid Cancers
E. Lastraioli, T. Lottini, L. Bencini, M. Bernini +1 more
2015BioMed Research International38 citations Open access
Semantic Scholar
KV11.1 Potassium Channel and the Na+/H+ Antiporter NHE1 Modulate Adhesion-Dependent Intracellular pH in Colorectal Cancer Cells
J. Iorio, Claudia Duranti, T. Lottini, E. Lastraioli +3 more
2020Frontiers in Pharmacology23 citations Open access
Semantic Scholar
Generation and characterization of novel recombinant anti-hERG1 scFv antibodies for cancer molecular imaging
Claudia Duranti, L. Carraresi, A. Sette, M. Stefanini +7 more
2018OncoTarget23 citations Open access
Semantic Scholar
Immunosuppressive contribution of tumour-infiltrating B cells in human intrahepatic cholangiocarcinoma and their role in chemoimmunotherapy outcome
Giulia Milardi, Barbara Franceschini, Chiara Camisaschi, S. Puccio +25 more
2025Gut22 citations Open access
Semantic Scholar
Harnessing the hERG1/β1 Integrin Complex via a Novel Bispecific Single-chain Antibody: An Effective Strategy against Solid Cancers
Claudia Duranti, J. Iorio, T. Lottini, E. Lastraioli +10 more
2021Molecular Cancer Therapeutics22 citations Open access
Semantic Scholar
hERG1 behaves as biomarker of progression to adenocarcinoma in Barrett's esophagus and can be exploited for a novel endoscopic surveillance
E. Lastraioli, T. Lottini, J. Iorio, G. Freschi +20 more
2016OncoTarget17 citations Open access
Semantic Scholar
Combination Therapy with a Bispecific Antibody Targeting the hERG1/β1 Integrin Complex and Gemcitabine in Pancreatic Ductal Adenocarcinoma
T. Lottini, Claudia Duranti, J. Iorio, Michele Martinelli +10 more
2023Cancers16 citations Open access
Semantic Scholar
Transgenic mice overexpressing the LH receptor in the female reproductive system spontaneously develop endometrial tumour masses
T. Lottini, J. Iorio, E. Lastraioli, L. Carraresi +6 more
2021Scientific Reports15 citations Open access
Semantic Scholar
Extracellular Signal‐Regulated Kinase 5 Regulates the Malignant Phenotype of Cholangiocarcinoma Cells
A. Gentilini, Giulia Lori, A. Caligiuri, C. Raggi +18 more
2021Hepatology15 citations Open access
Semantic Scholar
Targeting the hERG1/β1 integrin complex in lipid rafts potentiates statins anti-cancer activity in pancreatic cancer
Claudia Duranti, J. Iorio, V. Manganelli, G. Bagni +11 more
2025Cell Death Discovery9 citations Open access
Semantic Scholar
Limiting serine availability during tumor progression promotes muscle wasting in cancer cachexia
E. Pranzini, L. Muccillo, Ilaria Nesi, A. Santi +12 more
2024Cell Death Discovery9 citations Open access
Semantic Scholar
PHGDH drives 5-FU chemoresistance in colorectal cancer through the Hedgehog signaling
Caterina Mancini, Giulia Lori, G. Mattei, Marta Iozzo +21 more
2025Journal of experimental & clinical cancer research : CR8 citations Open access
Semantic Scholar
The hERG1 Potassium Channel Behaves As Prognostic Factor In Gastric Dysplasia Endoscopic Samples
E. Lastraioli, M. Romoli, J. Iorio, T. Lottini +10 more
2019OncoTargets and Therapy7 citations Open access
Semantic Scholar
Expression of the ether-a-gò-gò-related gene 1 channel during B and T lymphocyte development: role in BCR and TCR signaling
C. Sala, Martina Staderini, T. Lottini, Claudia Duranti +3 more
2023Frontiers in Immunology4 citations Open access
Semantic Scholar
LH/hCG-Receptor Expression May Have a Negative Prognostic Value in Low-Risk Endometrial Cancer
I. Noci, F. Sorbi, L. Mannini, Elisabetta Projetto +8 more
2016Frontiers in Oncology4 citations Open access
Semantic Scholar
Generation of an Orthotopic Xenograft of Pancreatic Cancer Cells by Ultrasound-Guided Injection.
T. Lottini, Matteo Buonamici, Claudia Duranti, A. Arcangeli
2021Journal of Visualized Experiments3 citations
Semantic Scholar
Correction: Clarithromycin inhibits autophagy in colorectal cancer by regulating the hERG1 potassium channel interaction with PI3K
G. Petroni, G. Bagni, J. Iorio, Claudia Duranti +5 more
2020Cell Death and Disease3 citations Open access
Semantic Scholar
A Mouse Model for Barrett’s Esophagus: Surgery and Histology
A. Taddei, T. Lottini, M. Fazi, M. Ringressi +3 more
20173 citations Open access
Semantic Scholar
Antineoplastic Activity of a Novel Trispecific Single-Chain Antibody Targeting the hERG1/β1 Integrin Complex and TRAIL Receptors
Claudia Duranti, J. Iorio, Chiara Capitani, T. Lottini +9 more
2025Molecular Cancer Therapeutics1 citations Open access
Semantic Scholar
Combined Inhibition of Smoothened and the DNA Damage Checkpoint WEE1 Exerts Antitumor Activity in Cholangiocarcinoma
G. Anichini, C. Raggi, M. Pastore, L. Carrassa +11 more
2022Molecular Cancer Therapeutics1 citations Open access
Semantic Scholar
WED-235 Involvement of the hERG1 potassium channel in cholangiocarcinoma cell biology
G. A. Viligiardi, J. Iorio, M. Pastore, C. Duranti +14 more
2026Journal of Hepatology0 citations Open access
Semantic Scholar
ASPARAGINE-RICH METASTATIC NICHES DRIVE PROSTATE CANCER ORGANOTROPISM BY ENABLING TRANSLATIONAL REWIRING TOWARD N-GLYCOSYLATED PROTEINS
E. Pranzini, L. Ippolito, M. Iozzo, S. Romagnoli +11 more
2026bioRxiv0 citations
Semantic Scholar
Corrigendum to “Transcriptomic data of Bevacizumab-adapted colorectal adenocarcinoma cells HCT-116” [Data In Brief, Volume 48, (Available online 17 March 2023) 1-9/Article 109069]
C. Sala, T. Lottini, E. Lastraioli, F. Ruffinatti +2 more
2023Data in Brief0 citations Open access
Semantic Scholar
Abstract 1216: Novel strategies in cancer immunotherapy: Harness the hERG1 β1 macromolecular complex via a new bispecific antibody and its bifunctional TRAIL
Claudia Duranti, J. Iorio, Stefano Coppola, G. Petroni +4 more
2019Experimental and Molecular Therapeutics0 citations
Semantic Scholar
The hERG1 Potassium Channel Behaves As Prognostic Factor In Gastric Dysplasia Endoscopic Samples
E. Lastraioli, M. Romoli, J. Iorio, T. Lottini +10 more
20190 citations
Semantic Scholar
Advances in hERG1 and LHR based targeting in neoplastic and preneoplastic conditions
T. Lottini
20170 citations
Semantic Scholar

Frequent co-authors

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A. Arcangeli×24
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A. Arcangeli — researcher profile on SciRah
J. Iorio×14
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J. Iorio — researcher profile on SciRah
Claudia Duranti×13
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Claudia Duranti — researcher profile on SciRah
E. Lastraioli×11
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C. Raggi — researcher profile on SciRah

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G. Bagni — researcher profile on SciRah

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M. Pastore — researcher profile on SciRah

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Giulia Lori — researcher profile on SciRah

L. di Tommaso×4

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L. di Tommaso — researcher profile on SciRah

M. Stefanini×4

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M. Stefanini — researcher profile on SciRah

L. Carraresi×4

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L. Carraresi — researcher profile on SciRah