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K. J. Mathis · SciRah

Researcher profile · Semantic Scholar

K. J. Mathis

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K. J. Mathis — researcher profile on SciRah

h-index: 11
Works: 26
Citations: 714

Most-cited papers

Molecular cloning and expression of human leukotriene-C4 synthase.
D. J. Welsch, D. P. Creely, S. Hauser, K. J. Mathis +2 more
1994Proceedings of the National Academy of Sciences of the United States of America124 citations Open access
Semantic Scholar
The titerless infected-cells preservation and scale-up (TIPS) method for large-scale production of NO-sensitive human soluble guanylate cyclase (sGC) from insect cells infected with recombinant baculovirus.
D. Wasilko, S. E. Lee, K. Stutzman-Engwall, B. Reitz +5 more
2009Protein Expression and Purification103 citations
Semantic Scholar
Orally active MMP-1 sparing α-tetrahydropyranyl and α-piperidinyl sulfone matrix metalloproteinase (MMP) inhibitors with efficacy in cancer, arthritis, and cardiovascular disease.
D. Becker, T. Barta, L. Bedell, T. Boehm +23 more
2010Journal of Medicinal Chemistry92 citations Open access
Semantic Scholar
High Resolution Crystal Structure of the Catalytic Domain of ADAMTS-5 (Aggrecanase-2)*
H. Shieh, K. J. Mathis, Jennifer M. Williams, Robert L. Hills +10 more
2008Journal of Biological Chemistry70 citations Open access
Semantic Scholar
Mistranslation in IGF-1 during over-expression of the protein in Escherichia coli using a synthetic gene containing low frequency codons.
R. Seetharam, Robert A. Heeren, Edith Wong, Sarah R. Braford +8 more
1988Biochemical and Biophysical Research Communications - BBRC67 citations
Semantic Scholar
2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: design and synthesis of a potent and isoform selective PKC-zeta inhibitor.
John I. Trujillo, J. Kiefer, Wei Huang, A. Thorarensen +12 more
2009Bioorganic & Medicinal Chemistry Letters56 citations Open access
Semantic Scholar
Structural and Inhibition Analysis Reveals the Mechanism of Selectivity of a Series of Aggrecanase Inhibitors
M. Tortorella, A. Tomasselli, K. J. Mathis, M. Schnute +7 more
2009Journal of Biological Chemistry55 citations Open access
Semantic Scholar
Expression of secreted insulin-like growth factor-1 in Escherichia coli.
Edith Wong, R. Seetharam, Claire E. Kotts, Robert A. Heeren +7 more
1988Gene38 citations
Semantic Scholar
Structure-based drug design enables conversion of a DFG-in binding CSF-1R kinase inhibitor to a DFG-out binding mode.
M. Meyers, M. Pelc, S. Kamtekar, Jacqueline E. Day +12 more
2010Bioorganic & Medicinal Chemistry Letters36 citations Open access
Semantic Scholar
Secretion of active kringle-2-serine protease in Escherichia coli.
M. Obukowicz, M. E. Gustafson, K. D. Junger, R. Leimgruber +6 more
1990Biochemistry30 citations
Semantic Scholar
Structure analysis reveals the flexibility of the ADAMTS‐5 active site
H. Shieh, A. Tomasselli, K. J. Mathis, Mark E. Schnute +8 more
2011Protein Science17 citations Open access
Semantic Scholar
MMP-13 selective α-sulfone hydroxamates: a survey of P1' heterocyclic amide isosteres.
T. Barta, D. Becker, L. Bedell, A. Easton +8 more
2011Bioorganic & Medicinal Chemistry Letters9 citations Open access
Semantic Scholar
High yield purification of soluble guanylate cyclase from bovine lung.
K. J. Mathis, T. L. Emmons, D. F. Curran, Jacqueline E. Day +1 more
2008Protein Expression and Purification6 citations
Semantic Scholar
Purification and characterization of recombinant human soluble guanylate cyclase produced from baculovirus-infected insect cells.
T. L. Emmons, K. J. Mathis, M. E. Shuck, B. Reitz +7 more
2009Protein Expression and Purification5 citations
Semantic Scholar
Purification and characterization of progenipoietins produced in Escherichia. coli.
B. Violand, J. Minnerly, Yiqing Feng, J. Polazzi +3 more
2002Protein Expression and Purification3 citations
Semantic Scholar
Mammalian cell production and purification of progenipoietin, a dual‐agonist chimaeric haematopoietic growth factor
David C. Wood, K. J. Mathis, W. D. Joy, John C. Minnerly +2 more
2003Biotechnology and applied biochemistry2 citations
Semantic Scholar
Graphical contents list
T. Barta, D. Becker, L. Bedell, A. Easton +23 more
2011Bioorganic & Medicinal Chemistry Letters0 citations Open access
Semantic Scholar
MMP-13 in complex with selective tetrazole core inhibitor
J. Kiefer, T. Barta, D. Becker, K. J. Mathis +1 more
20110 citations
Semantic Scholar
Structure Analysis Reveals the Vulnerability of the ADAMTS-5 Active Site
H. Shieh, A. Tomasselli, K. J. Mathis, M. Schnute +7 more
20100 citations
Semantic Scholar
Inhibitor Bound to A DFG-Out structure of the Kinase Domain of CSF-1R
S. Kamtekar, Jacqueline E. Day, B. Reitz, K. J. Mathis +1 more
20100 citations
Semantic Scholar
Crystal Structure of the Catalytic Domain of ADAMTS-5 in Complex with an Amino-2-indanol compound
H. Shieh, Jennifer M. Williams, N. Caspers, K. J. Mathis +2 more
20090 citations
Semantic Scholar
CDK-2-Cyclin complex with indazole inhibitor 9 bound at its active site
J. Kiefer, Jacqueline E. Day, N. Caspers, K. J. Mathis +12 more
20090 citations
Semantic Scholar
CDK-2 with indazole inhibitor 17 bound at its active site
J. Kiefer, Jacqueline E. Day, N. Caspers, K. J. Mathis +12 more
20090 citations
Semantic Scholar
Crystal Structure of the Catalytic Domain of ADAMTS-5 in Complex with Marimastat
H. Shieh, Jennifer M. Williams, N. Caspers, K. J. Mathis +2 more
20090 citations
Semantic Scholar
Aggrecanase Inhibitors the Mechanism of Selectivity of a Series of Structural and Inhibition Analysis Reveals Protein Structure and Folding
M. Tortorella, A. Tomasselli, K. J. Mathis, S. Woodard +6 more
20090 citations
Semantic Scholar
Binding of [3H]BAY 58-2667 to purified bovine lung soluble guanylate cyclase by scintillation proximity assay
P. Garner-Hamrick, K. J. Mathis, T. Emmons, M. Tones
20050 citations Open access
Semantic Scholar

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