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R. Chiaraluce · SciRah

Researcher profile · Semantic Scholar

R. Chiaraluce

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R. Chiaraluce — researcher profile on SciRah

h-index: 23
Works: 83
Citations: 1,955

Most-cited papers

The structure of Pyrococcus furiosus glutamate dehydrogenase reveals a key role for ion-pair networks in maintaining enzyme stability at extreme temperatures.
Kitty S. P. Yip, T. J. Stillman, K. Britton, P. Artymiuk +8 more
1995Structure410 citations Open access
Semantic Scholar
Protein thermostability in extremophiles.
Roberto Scandurra, V. Consalvi, R. Chiaraluce, L. Politi +1 more
1998Biochimie135 citations
Semantic Scholar
Extremely thermostable glutamate dehydrogenase from the hyperthermophilic archaebacterium Pyrococcus furiosus.
V. Consalvi, R. Chiaraluce, L. Politi, Rosaria Vaccaro +2 more
1991European Journal of Biochemistry94 citations Open access
Semantic Scholar
Analysis and Interpretation of the Impact of Missense Variants in Cancer
M. Petrosino, L. Novak, A. Pasquo, R. Chiaraluce +3 more
2021International Journal of Molecular Sciences77 citations Open access
Semantic Scholar
A semi-synthetic repertoire of intrinsically stable antibody fragments derived from a single-framework scaffold.
A. Desiderio, R. Franconi, M. Lopez, Maria Elena Villani +5 more
2001Journal of Molecular Biology77 citations
Semantic Scholar
Glutamate dehydrogenase from the thermoacidophilic archaebacterium Sulfolobus solfataricus.
V. Consalvi, R. Chiaraluce, L. Politi, A. Gambacorta +2 more
1991European Journal of Biochemistry70 citations
Semantic Scholar
The protein sequence of glutamate dehydrogenase from Sulfolobus solfataricus, a thermoacidophilic archaebacterium. Is the presence of N-epsilon-methyllysine related to thermostability?
Bruno Maras, V. Consalvi, R. Chiaraluce, L. Politi +4 more
1992European Journal of Biochemistry68 citations
Semantic Scholar
Thermal unfolding and conformational stability of the recombinant domain II of glutamate dehydrogenase from the hyperthermophile Thermotoga maritima.
V. Consalvi, R. Chiaraluce, L. Giangiacomo, Roberto Scandurra +4 more
2000Protein Engineering61 citations
Semantic Scholar
A single-chain antibody fragment is functionally expressed in the cytoplasm of both Escherichia coli and transgenic plants.
P. Tavladoraki, Alessandra Girotti, M. Donini, F. Arias +5 more
1999European Journal of Biochemistry55 citations Open access
Semantic Scholar
The unusual co-assembly of H- and M-chains in the ferritin molecule from the Antarctic teleosts Trematomus bernacchii and Trematomus newnesi.
A. Giorgi, G. Mignogna, Giuliano Bellapadrona, M. Gattoni +4 more
2008Archives of Biochemistry and Biophysics53 citations
Semantic Scholar
Computational and Experimental Studies on β-Sheet Breakers Targeting Aβ1–40 Fibrils
V. Minicozzi, R. Chiaraluce, V. Consalvi, C. Giordano +4 more
2014Journal of Biological Chemistry51 citations Open access
Semantic Scholar
Protein stability in extremophilic archaea.
Roberto Scandurra, Valerio Consalvi, R. Chiaraluce, L. Politi +1 more
2000Frontiers in Bioscience41 citations Open access
Semantic Scholar
Crystal structure of a family 16 endoglucanase from the hyperthermophile Pyrococcus furiosus– structural basis of substrate recognition
A. Ilari, A. Fiorillo, S. Angelaccio, R. Florio +3 more
2009The FEBS Journal38 citations Open access
Semantic Scholar
Oxalate, phosphate and sulphate determination in serum and urine by ion chromatography.
L. Politi, R. Chiaraluce, Valerio Consalvi, Nicola Cerulli +1 more
1989Clinica chimica acta; international journal of clinical chemistry36 citations
Semantic Scholar
Continuous spectrophotometric assay of pantetheinase activity.
Silvestro Dupré, R. Chiaraluce, M. Nardini, C. Cannella +2 more
1984Analytical Biochemistry31 citations
Semantic Scholar
Structural and thermodynamic studies on a salt-bridge triad in the NADP-binding domain of glutamate dehydrogenase from Thermotoga maritima: cooperativity and electrostatic contribution to stability.
J. Lebbink, V. Consalvi, R. Chiaraluce, K. Berndt +1 more
2002Biochemistry30 citations
Semantic Scholar
Exchange of domains of glutamate dehydrogenase from the hyperthermophilic archaeon Pyrococcus furiosus and the mesophilic bacterium Clostridium difficile: effects on catalysis, thermoactivity and stability.
J. Lebbink, R. Eggen, A. Geerling, V. Consalvi +3 more
1995Protein Engineering30 citations Open access
Semantic Scholar
Catalytic and Thermodynamic Properties of Tetrahydromethanopterin-dependent Serine Hydroxymethyltransferase from Methanococcus jannaschii*
S. Angelaccio, R. Chiaraluce, V. Consalvi, Barbara Buchenau +3 more
2003Journal of Biological Chemistry28 citations Open access
Semantic Scholar
Ferritin from the spleen of the Antarctic teleost Trematomus bernacchii is an M-type homopolymer.
G. Mignogna, R. Chiaraluce, V. Consalvi, S. Cavallo +2 more
2002European Journal of Biochemistry28 citations
Semantic Scholar
Synthesis and activity of fibrillogenesis peptide inhibitors related to the 17-21 beta-amyloid sequence.
C. Giordano, A. Masi, A. Pizzini, A. Sansone +3 more
2009European journal of medicinal chemistry27 citations
Semantic Scholar
The unusual dodecameric ferritin from Listeria innocua dissociates below pH 2.0.
R. Chiaraluce, V. Consalvi, S. Cavallo, A. Ilari +2 more
2000European Journal of Biochemistry27 citations
Semantic Scholar
Effect of Single Amino Acid Substitution Observed in Cancer on Pim-1 Kinase Thermodynamic Stability and Structure
C. Lori, Antonella Lantella, A. Pasquo, L. Alexander +3 more
2013PLoS ONE24 citations Open access
Semantic Scholar
The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme
A. Fiorillo, M. Petrosino, A. Ilari, A. Pasquo +4 more
2018PLoS ONE23 citations Open access
Semantic Scholar
The amino acid sequence of glutamate dehydrogenase fromPyrococcus furiosus, a hyperthermophilic archaebacterium
B. Maras, S. Valiante, R. Chiaraluce, V. Consalvi +5 more
1994Journal of Protein Chemistry23 citations
Semantic Scholar
DNA-binding Activity of the ERp57 C-terminal Domain Is Related to a Redox-dependent Conformational Change*
Caterina Grillo, C. D'Ambrosio, V. Consalvi, R. Chiaraluce +4 more
2007Journal of Biological Chemistry21 citations Open access
Semantic Scholar
Effect of BET Missense Mutations on Bromodomain Function, Inhibitor Binding and Stability
L. Lori, A. Pasquo, C. Lori, M. Petrosino +4 more
2016PLoS ONE19 citations Open access
Semantic Scholar
The effect of β-sheet breaker peptides on metal associated Amyloid-β peptide aggregation process.
F. Stellato, Zelio Fusco, R. Chiaraluce, V. Consalvi +6 more
2017Biophysical Chemistry18 citations
Semantic Scholar
Refolding pathway and association intermediates of glutamate dehydrogenase from the hyperthermophile Pyrococcus furiosus.
Valerio Consalvi, R. Chiaraluce, Stefania Millevoi, Alessandra Pasquo +3 more
1996European Journal of Biochemistry18 citations
Semantic Scholar
Evaluating the predictions of the protein stability change upon single amino acid substitutions for the FXN CAGI5 challenge
Castrense Savojardo, M. Petrosino, G. Babbi, Samuele Bovo +21 more
2019Human Mutation17 citations Open access
Semantic Scholar
Human Mutation
M. Petrosino, A. Pasquo, L. Novak, A. Toto +9 more
201917 citations
Semantic Scholar
Humanization of a highly stable single-chain antibody by structure-based antigen-binding site grafting.
Maria Elena Villani, V. Morea, V. Consalvi, R. Chiaraluce +3 more
2008Molecular Immunology17 citations
Semantic Scholar
Zn‐Induced Interactions Between SARS‐CoV‐2 orf7a and BST2/Tetherin
M. Petrosino, F. Stellato, R. Chiaraluce, V. Consalvi +5 more
2021ChemistryOpen16 citations Open access
Semantic Scholar
Structural Stability of Human Protein Tyrosine Phosphatase ρ Catalytic Domain: Effect of Point Mutations
A. Pasquo, V. Consalvi, S. Knapp, I. Alfano +3 more
2012PLoS ONE16 citations Open access
Semantic Scholar
The mutations Lys 114 → Gln and Asp 126 → Asn disrupt an intersubunit salt bridge and convert Listeria innocua Dps into its natural mutant Listeria monocytogenes Dps. Effects on protein stability at Low pH
Giuliano Bellapadrona, R. Chiaraluce, V. Consalvi, A. Ilari +2 more
2006Proteins: Structure, Function, and Bioinformatics16 citations
Semantic Scholar
Production of functional, stable, unmutated recombinant human papillomavirus E6 oncoprotein: implications for HPV-tumor diagnosis and therapy
E. Illiano, O. Demurtas, Silvia Massa, P. Di Bonito +7 more
2016Journal of Translational Medicine15 citations Open access
Semantic Scholar
Inhibition of Amyloid Peptide Fragment Aβ25–35 Fibrillogenesis and Toxicity by N‐Terminal β‐Amino Acid‐Containing Esapeptides: Is Taurine Moiety Essential for In Vivo Effects?
C. Giordano, A. Sansone, A. Masi, A. Masci +4 more
2012Chemical Biology and Drug Design15 citations Open access
Semantic Scholar
The role of evolutionarily conserved hydrophobic contacts in the quaternary structure stability of Escherichia coli serine hydroxymethyltransferase
R. Florio, R. Chiaraluce, V. Consalvi, A. Paiardini +3 more
2009The FEBS Journal15 citations Open access
Semantic Scholar
Persistence of tertiary structure in 7.9 M guanidinium chloride: the case of endo-beta-1,3-glucanase from Pyrococcus furiosus.
R. Chiaraluce, J. van der Oost, J. Lebbink, T. Kaper +1 more
2002Biochemistry14 citations Open access
Semantic Scholar
Stability, refolding and Ca2+ binding of pullulanase from the hyperthermophilic archaeon Pyrococcus woesei.
R. Schwerdtfeger, R. Chiaraluce, V. Consalvi, Roberto Scandurra +1 more
1999European Journal of Biochemistry14 citations
Semantic Scholar
Biological Effects of MC2050, a Quinazoline‐Based PARP‐1 Inhibitor, in Human Neuroblastoma and EBV‐Positive Burkitt′s Lymphoma Cells
L. Mosca, D. Rotili, I. Tempera, A. Masci +5 more
2011ChemMedChem12 citations
Semantic Scholar
Glutamate dehydrogenase from the thermoacidophilic archaebacterium Sulfolobus solfataricus: studies on thermal and guanidine-dependent inactivation.
V. Consalvi, R. Chiaraluce, L. Politi, A. Pasquo +2 more
1993Biochimica et Biophysica Acta12 citations
Semantic Scholar
The complex impact of cancer-related missense mutations on the stability and on the biophysical and biochemical properties of MAPK1 and MAPK3 somatic variants
Maria Petrosino, L. Novak, A. Pasquo, Paola Turina +4 more
2023Human Genomics11 citations Open access
Semantic Scholar
Single-Nucleotide Polymorphism of PPARγ, a Protein at the Crossroads of Physiological and Pathological Processes
M. Petrosino, L. Lori, A. Pasquo, C. Lori +7 more
2017International Journal of Molecular Sciences11 citations Open access
Semantic Scholar
Structural basis of the transactivation deficiency of the human PPARγ F360L mutant associated with familial partial lipodystrophy.
C. Lori, A. Pasquo, R. Montanari, D. Capelli +8 more
2014Acta Crystallographica Section D: Biological Crystallography10 citations Open access
Semantic Scholar
Oligomerization of Sulfolobus solfataricus signature amidase is promoted by acidic pH and high temperature.
Anna Scotto D'Abusco, R. Casadio, Gianluca Tasco, L. Giangiacomo +7 more
2005Archaea10 citations Open access
Semantic Scholar
β‐Sheet Breaker Peptides Containing α,β‐Dehydrophenylalanine: Synthesis and In Vitro Activity Studies
C. Giordano, Pasqualina Punzi, C. Lori, R. Chiaraluce +1 more
20149 citations
Semantic Scholar
Calcium-induced tertiary structure modifications of endo-beta-1,3-glucanase from Pyrococcus furiosus in 7.9 M guanidinium chloride.
R. Chiaraluce, Giulio Gianese, S. Angelaccio, R. Florio +3 more
2005Biochemical Journal9 citations Open access
Semantic Scholar
Refolding of glutamate dehydrogenase from Bacillus acidocaldarius after guanidinium chloride-induced unfolding.
V. Consalvi, S. Millevoi, R. Chiaraluce, M. de Rosa +1 more
1995Biochemistry and molecular biology international9 citations
Semantic Scholar
Interaction of pantetheinase with sulfhydryl reagents and disulfides.
Giorgio Ricci, M. Nardini, R. Chiaraluce, Silvestro Dupré +1 more
1986Biochimica et Biophysica Acta9 citations
Semantic Scholar
Dealing with Cu reduction in X-ray absorption spectroscopy experiments.
F. Stellato, R. Chiaraluce, V. Consalvi, E. de Santis +4 more
2019Metallomics8 citations
Semantic Scholar

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V. Consalvi — researcher profile on SciRah
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