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A. Thedrez · SciRah

Researcher profile · Semantic Scholar

A. Thedrez

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A. Thedrez — researcher profile on SciRah

h-index: 17
Works: 35
Citations: 1,028

Most-cited papers

Self/non‐self discrimination by human γδ T cells: simple solutions for a complex issue?
A. Thedrez, C. Sabourin, J. Gertner, M. Devilder +4 more
2007141 citations
Semantic Scholar
PCSK9 Modulates the Secretion But Not the Cellular Uptake of Lipoprotein(a) Ex Vivo
E. Villard, A. Thedrez, J. Blankenstein, M. Croyal +12 more
2016JACC: Basic to Translational Science128 citations Open access
Semantic Scholar
Self/non-self discrimination by human gammadelta T cells: simple solutions for a complex issue?
A. Thedrez, C. Sabourin, J. Gertner, M. Devilder +4 more
2007Immunological Reviews94 citations
Semantic Scholar
Homozygous FH Patients with Identical Mutations Variably Express the LDL Receptor: Implications for the Efficacy of Evolocumab
A. Thedrez, D. Blom, S. Ramin-Mangata, V. Blanchard +10 more
2017Arteriosclerosis, Thrombosis and Vascular Biology87 citations Open access
Semantic Scholar
Immunity of human epithelial ovarian carcinoma: the paradigm of immune suppression in cancer
V. Lavoué, A. Thedrez, J. Levêque, F. Foucher +5 more
2013Journal of Translational Medicine67 citations Open access
Semantic Scholar
PCSK9 and lipoprotein (a) levels are two predictors of coronary artery calcification in asymptomatic patients with familial hypercholesterolemia.
R. Alonso, P. Mata, O. Muñiz, F. Fuentes-Jiménez +8 more
2016Atherosclerosis65 citations
Semantic Scholar
IL-21-Mediated Potentiation of Antitumor Cytolytic and Proinflammatory Responses of Human Vγ9Vδ2 T Cells for Adoptive Immunotherapy1
A. Thedrez, C. Harly, Alexis Morice, S. Salot +2 more
2009Journal of Immunology62 citations Open access
Semantic Scholar
CD4 engagement by CD1d potentiates activation of CD4+ invariant NKT cells.
A. Thedrez, C. de Lalla, Sophie Allain, Luca Zaccagnino +7 more
2007Blood59 citations
Semantic Scholar
PCSK9 inhibition with alirocumab reduces lipoprotein(a) levels in nonhuman primates by lowering apolipoprotein(a) production rate.
M. Croyal, Thi-Thu-Trang Tran, R. Blanchard, J. Le Bail +15 more
2018Clinical science41 citations
Semantic Scholar
The complexity of lipoprotein (a) lowering by PCSK9 monoclonal antibodies.
G. Lambert, A. Thedrez, M. Croyal, S. Ramin-Mangata +9 more
2017Clinical science36 citations Open access
Semantic Scholar
Characterization of the first PCSK9 gain of function homozygote.
A. C. Alves, A. Etxebarria, A. Medeiros, A. Benito-Vicente +6 more
2015Journal of the American College of Cardiology34 citations Open access
Semantic Scholar
Normalization of low-density lipoprotein receptor expression in receptor defective homozygous familial hypercholesterolemia by inhibition of PCSK9 with alirocumab.
G. Lambert, M. Chatelais, F. Petrides, Maxime Passard +7 more
2014Journal of the American College of Cardiology33 citations Open access
Semantic Scholar
Effects of proprotein convertase subtilisin kexin type 9 modulation in human pancreatic beta cells function.
S. Ramin-Mangata, A. Thedrez, B. Nativel, N. Diotel +15 more
2021Atherosclerosis23 citations Open access
Semantic Scholar
Circulating PCSK9 levels are not associated with the conversion to type 2 diabetes.
S. Ramin-Mangata, M. Wargny, M. Pichelin, C. Le May +8 more
2019Atherosclerosis23 citations Open access
Semantic Scholar
Proprotein Convertase Subtilisin Kexin Type 9 Inhibition for Autosomal Recessive Hypercholesterolemia—Brief Report
A. Thedrez, B. Sjouke, Maxime Passard, Simon Prampart-Fauvet +15 more
2016Arteriosclerosis, Thrombosis and Vascular Biology22 citations Open access
Semantic Scholar
Sensitization of ovarian carcinoma cells with zoledronate restores the cytotoxic capacity of Vγ9Vδ2 T cells impaired by the prostaglandin E2 immunosuppressive factor: Implications for immunotherapy
V. Lavoué, F. Cabillic, O. Toutirais, A. Thedrez +11 more
2012International Journal of Cancer20 citations Open access
Semantic Scholar
Identification of a Gain-of-Function LIPC Variant as a Novel Cause of Familial Combined Hypocholesterolemia
W. Dijk, M. Di Filippo, S. Kooijman, R. van Eenige +18 more
2022Circulation19 citations Open access
Semantic Scholar
A Quantitative Deficiency in Peripheral Blood Vγ9Vδ2 Cells Is a Negative Prognostic Biomarker in Ovarian Cancer Patients
A. Thedrez, V. Lavoué, Benoît Dessarthe, P. Daniel +5 more
2013PLoS ONE16 citations Open access
Semantic Scholar
FACS-assisted CRISPR-Cas9 genome editing of human induced pluripotent stem cells
A. Caillaud, Antoine Lévêque, A. Thedrez, A. Girardeau +12 more
2022STAR Protocols14 citations Open access
Semantic Scholar
CRTAM Receptor Engagement by Necl-2 on Tumor Cells Triggers Cell Death of Activated Vγ9Vδ2 T Cells
Benoît Dessarthe, A. Thedrez, J. Latouche, F. Cabillic +5 more
2013Journal of Immunology13 citations Open access
Semantic Scholar
Plasma PCSK9 measurement by liquid chromatography-Tandem mass spectrometry and comparison with conventional ELISA.
M. Croyal, F. Fall, M. Krempf, A. Thedrez +8 more
2017Journal of chromatography. B, Analytical technologies in the biomedical and life sciences11 citations
Semantic Scholar
[Nectins and nectin-like receptors DNAM-1 and CRTAM: new ways for tumor escape].
V. Catros, Benoît Dessarthe, A. Thedrez, O. Toutirais
2014Medecine sciences : M/S8 citations Open access
Semantic Scholar
PCSK9 is not secreted from mature differentiated intestinal cells
F. Moreau, A. Thedrez, D. Garçon, A. Ayer +14 more
2021Journal of Lipid Research6 citations Open access
Semantic Scholar
IMMUNOBIOLOGY CD 4 engagement by CD 1 d potentiates activation of CD 4 + invariant NKT cells
A. Thedrez, C. de Lalla, Sophie Allain, Luca Zaccagnino +7 more
20073 citations
Semantic Scholar
Immunity of human epithelial ovarian carcinoma: the paradigm of immune suppression in cancer
V. Lavoué, A. Thedrez, J. Levêque, F. Foucher +5 more
2013Journal of Translational Medicine2 citations Open access
Semantic Scholar
LDL receptor (LDLR) expression and function in human pancreatic beta cells
A. Thedrez, R. Scharfmann, P. Parnet, E. Nobécourt +1 more
20161 citations
Semantic Scholar
CD4 engagement by CD1d potentiates activation of CD4 (cid:1) invariant NKT cells
A. Thedrez, C. de Lalla, Sophie Allain, Luca Zaccagnino +7 more
20071 citations
Semantic Scholar
Corrigendum: PCSK9 is not secreted from mature differentiated intestinal cells.
F. Moreau, A. Thedrez, D. Garçon, A. Ayer +14 more
2022Journal of Lipid Research0 citations Open access
Semantic Scholar
Comment on: Proprotein convertase subtilisin/kexin type 9 in the dyslipidaemia of patients with axial spondyloarthritis is related to disease activity.
M. Heslinga, G. Lambert, A. Thedrez, J. Kastelein +1 more
2021Rheumatology0 citations Open access
Semantic Scholar
Development and automation of 3D innovative hiPSC-based liver organoids including the microenvironment for phenotyping screening - application on metabolic diseases
Roudaut Méryl, Caillaud Amandine, Girardeau Aurore, Mikaël Croyal +10 more
2020Journal of Hepatology0 citations Open access
Semantic Scholar
LDL receptor (LDLR) expression and LDL uptake in human pancreatic beta cells are regulated by statins and PCSK9 - Consequence for glucose-stimulated insulin secretion (GSIS)
S. Ramin-Mangata, A. Thedrez, B. Cariou, R. Scharfmann +2 more
2018Atherosclerosis0 citations
Semantic Scholar
THU0154 Association between plasma lipids, disease activity and PCSK9 levels in RA patients
M. Heslinga, G. Lambert, A. Thedrez, J. Kastelein +1 more
20170 citations Open access
Semantic Scholar
Alirocumab efficiently reduces Lp(a) levels by lowering apolipoprotein (a) [apo(a)] production rate in non-human primates (NHP).
M. Croyal, Thi-Thu-Trang Tran, R. Blanchard, J. Le Bail +7 more
2017Atherosclerosis0 citations
Semantic Scholar
CD 4 engagement by CD 1 d potentiates activation of CD 4 invariant NKT cells
A. Thedrez, C. de Lalla, Sophie Allain, Luca Zaccagnino +7 more
20070 citations
Semantic Scholar
Activated Tumor Cells Triggers Cell Death of Crtam Receptor Engagement by Necl-2 On
Toutirais Thomas De, La Pintière, V. Catros, Olivier Florian Cabillic +5 more
0 citations
Semantic Scholar

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