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L. Organ · SciRah

Researcher profile · Semantic Scholar

L. Organ

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L. Organ — researcher profile on SciRah

h-index: 13
Works: 33
Citations: 686

Most-cited papers

Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue
J. Aguiar, B. J. Tremblay, Michael J. Mansfield, Owen Z. Woody +20 more
2020European Respiratory Journal170 citations Open access
Semantic Scholar
Biomarkers of collagen synthesis predict progression in the PROFILE idiopathic pulmonary fibrosis cohort
L. Organ, A. Duggan, E. Oballa, Sarah C. Taggart +13 more
2018bioRxiv118 citations Open access
Semantic Scholar
Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis
A. John, Rebecca H. Graves, Tao K. Pun, G. Vitulli +33 more
2020Nature Communications116 citations Open access
Semantic Scholar
Perspectives on precision cut lung slices—powerful tools for investigation of mechanisms and therapeutic targets in lung diseases
M. Lam, Emma Lamanna, L. Organ, C. Donovan +1 more
2023Frontiers in Pharmacology45 citations Open access
Semantic Scholar
CXCR4+ cells are increased in lung tissue of patients with idiopathic pulmonary fibrosis
J. Jaffar, Katherine Griffiths, S. Oveissi, M. Duan +5 more
2020Respiratory Research36 citations Open access
Semantic Scholar
Structural and functional correlations in a large animal model of bleomycin-induced pulmonary fibrosis
L. Organ, B. Bacci, E. Koumoundouros, G. Barcham +4 more
2015BMC Pulmonary Medicine34 citations Open access
Semantic Scholar
A novel segmental challenge model for bleomycin-induced pulmonary fibrosis in sheep
L. Organ, B. Bacci, E. Koumoundouros, G. Barcham +4 more
2015Experimental Lung Research27 citations
Semantic Scholar
Inhibition of the KCa3.1 Channel Alleviates Established Pulmonary Fibrosis in a Large Animal Model
L. Organ, B. Bacci, E. Koumoundouros, W. Kimpton +7 more
2017American Journal of Respiratory Cell and Molecular Biology25 citations
Semantic Scholar
S31 The novel coronavirus SARS-CoV-2 binds RGD integrins and upregulates avb3 integrins in Covid-19 infected lungs
J. Calver, C. Joseph, A. John, L. Organ +11 more
202120 citations Open access
Semantic Scholar
Tetrathiomolybdate Treatment Attenuates Bleomycin-Induced Angiogenesis and Lung Pathology in a Sheep Model of Pulmonary Fibrosis
H. B. Derseh, K. U. E. Perera, Sasika N. Vithana Dewage, A. Stent +4 more
2021Frontiers in Pharmacology18 citations Open access
Semantic Scholar
KCa3.1 channel blockade attenuates microvascular remodelling in a large animal model of bleomycin-induced pulmonary fibrosis
H. B. Derseh, Sasika N. Vithana Dewage, K. U. E. Perera, C. N. Pagel +3 more
2019Scientific Reports18 citations Open access
Semantic Scholar
The Effects of Tumstatin on Vascularity, Airway Inflammation and Lung Function in an Experimental Sheep Model of Chronic Asthma
Joanne L. Van der Velden, L. Harkness, Donna M. Barker, G. Barcham +7 more
2016Scientific Reports18 citations Open access
Semantic Scholar
The efficacy of pirfenidone in a sheep model of pulmonary fibrosis
S. Dewage, L. Organ, E. Koumoundouros, H. B. Derseh +4 more
2019Experimental Lung Research14 citations
Semantic Scholar
Increased Levels of ER Stress and Apoptosis in a Sheep Model for Pulmonary Fibrosis Are Alleviated by In Vivo Blockade of the KCa3.1 Ion Channel
U. E. Perera, L. Organ, Sasika N. V. Dewage, H. B. Derseh +2 more
2020Canadian Respiratory Journal11 citations Open access
Semantic Scholar
Small airway remodeling in a sheep model of bleomycin-induced pulmonary fibrosis
H. B. Derseh, Sasika N. Vithana Dewage, U. E. Perera, E. Koumoundouros +3 more
2020Experimental Lung Research8 citations
Semantic Scholar
Development and characterization of AD-214, an anti-CXCR4 i-body-Fc fusion for the treatment of idiopathic pulmonary fibrosis
Jason P. Lynch, L. Organ, Khamis Tomusange, Lukasz Kowalczyk +4 more
2025mAbs4 citations Open access
Semantic Scholar
Comparative Study of Ectopic Lymphoid Aggregates in Sheep and Murine Models of Bleomycin-Induced Pulmonary Fibrosis
U. E. Perera, L. Organ, S. Royce, C. Samuel +5 more
2023Canadian Respiratory Journal4 citations Open access
Semantic Scholar
Investigating the role of AKAP13 on epithelial cell TGFß activation
L. Organ, J. Porte, A. John, G. Jenkins
2019Mechanisms of lung injury and repair1 citations
Semantic Scholar
Binding of SARS-CoV-2 to the avb6 Integrins May Promote Severe COVID in Patients with IPF
C. Joseph, T. Peacock, J. Calver, A. John +13 more
2021TP105. TP105 BASIC MECHANISMS OF LUNG INFECTIONS: FROM SARS-COV-2 TO INFLUENZA0 citations
Semantic Scholar
A Comparison of Secondary Lymphoid Follicle Development in Two Animal Models of Pulmonary Fibrosis
K. U. E. Perera, L. Organ, S. Royce, H. B. Derseh +4 more
20200 citations
Semantic Scholar
Tetrathiomolybdate Treatment Attenuates Microvascular Remodeling in a Large Animal Model of Bleomycin Induced Pulmonary Fibrosis
H. B. Derseh, K. U. E. Perera, V. D. S. D. S. Nimanthi, E. Koumoundouros +3 more
2020A68. PARENCHYMA/INTERSTITIAL LUNG DISEASE0 citations
Semantic Scholar
Mast Cell Changes in Two Different Treatment Groups of A Sheep Model of Pulmonary Fibrosis
R. Bijani, Nimanthi Vds, L. Organ, K. Snibson
20200 citations
Semantic Scholar
Tetrathiomolybdate Treatment Attenuates Bleomycin-Induced Pulmonary Fibrosis in a Large Animal Model
H. B. Derseh, K. U. E. Perera, V. D. S. D. S. Nimanthi, E. Koumoundouros +4 more
2019A108. PATHOPHYSIOLOGY IN DIFFUSE PARENCHYMAL LUNG DISEASES0 citations
Semantic Scholar
In vivo blockade of KCa3.1 ion channel alleviates ER stress in type II alveolar epithelial cells and macrophages in pulmonary fibrosis
K. U. E. Perera, Sasika Nimanthi Vithana Dewage, H. B. Derseh, Paul John Benham +3 more
2019Idiopathic interstitial pneumonias0 citations
Semantic Scholar
The effect of mast cell stabilisation in a large animal model of pulmonary fibrosis
S. Dewage, A. Stent, H. B. Derseh, K. U. E. Perera +2 more
2019Idiopathic interstitial pneumonias0 citations
Semantic Scholar
Could airway basal cells be a novel predictor of mortality in IPF?
L. Organ
2019Breathe0 citations Open access
Semantic Scholar
Effect of in vivo blockade of the KCa3.1 ion channel on type II alveolar epithelial cell turnover in pulmonary fibrosis
K. U. E. Perera, L. Organ, H. B. Derseh, Sasika N. V. Dewage +2 more
2018Idiopathic interstitial pneumonias0 citations
Semantic Scholar
LATE-BREAKING ABSTRACT: KCa3.1 ion channel-blockade reduces pulmonary fibrotic responses via the inhibition of fibroblast proliferation
L. Organ, E. Koumoundouros, B. Bacci, W. Kimpton +5 more
20160 citations
Semantic Scholar
The development of a sheep model of pulmonary fibrosis
L. Organ
20160 citations
Semantic Scholar
KCa3.1 channel-blockade reduces both human and ovine pulmonary fibroblast proliferation in vitro
L. Organ, K. Snibson, I. Glaspole, G. Westall +1 more
20160 citations
Semantic Scholar
University of Groningen The Effects of Tumstatin on Vascularity , Airway Inflammation and Lung Function in an Experimental Sheep Model of Chronic Asthma
Joanne L. Van der Velden, L. Harkness, Donna M. Barker, G. Barcham +7 more
20160 citations
Semantic Scholar
STRUCTURAL AND FUNCTIONAL CHANGES IN A SEGMENTAL CHALLENGE MODEL OF BLEOMYCIN-INDUCED INJURY
L. Organ, E. Koumoundouros, B. Bacci, G. Barcham +5 more
20150 citations
Semantic Scholar
The persistence of pulmonary fibrosis in a segmental challenge model of Bleomycin-induced injury
L. Organ, E. Koumoundouros, B. Bacci, G. Barcham +2 more
20140 citations
Semantic Scholar

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K. Snibson×19
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E. Koumoundouros×16
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H. B. Derseh×12
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C. Samuel — researcher profile on SciRah

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C. N. Pagel — researcher profile on SciRah

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