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J. Porte · SciRah

Researcher profile · Semantic Scholar

J. Porte

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J. Porte — researcher profile on SciRah

h-index: 15
Works: 47
Citations: 1,056

Most-cited papers

Lysophosphatidic acid induces alphavbeta6 integrin-mediated TGF-beta activation via the LPA2 receptor and the small G protein G alpha(q).
Ming-Yan Xu, J. Porte, A. Knox, P. Weinreb +5 more
2009American Journal of Pathology215 citations Open access
Semantic Scholar
An epithelial biomarker signature for idiopathic pulmonary fibrosis: an analysis from the multicentre PROFILE cohort study.
Toby M. Maher, E. Oballa, J. Simpson, J. Porte +20 more
2018184 citations
Semantic Scholar
Integrin αVβ5 Mediated TGF-β Activation by Airway Smooth Muscle Cells in Asthma
Amanda L. Tatler, A. John, L. Jolly, A. Habgood +7 more
2011Journal of Immunology136 citations Open access
Semantic Scholar
αvβ6 integrin may be a potential prognostic biomarker in interstitial lung disease
Gauri Saini, J. Porte, P. Weinreb, S. Violette +3 more
2015European Respiratory Journal91 citations Open access
Semantic Scholar
Influenza Promotes Collagen Deposition via αvβ6 Integrin-mediated Transforming Growth Factor β Activation*
L. Jolly, A. Stavrou, Gilles Vanderstoken, Victoria A. Meliopoulos +11 more
2014Journal of Biological Chemistry55 citations Open access
Semantic Scholar
Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis
Amanda L. Tatler, Amanda T. Goodwin, O. Gbolahan, Gauri Saini +10 more
2016PLoS ONE47 citations Open access
Semantic Scholar
Tryptase activates TGFbeta in human airway smooth muscle cells via direct proteolysis.
Amanda L. Tatler, J. Porte, A. Knox, G. Jenkins +1 more
2008Biochemical and Biophysical Research Communications - BBRC42 citations
Semantic Scholar
Reduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin αvβ6 Expression
Amanda L. Tatler, A. Habgood, J. Porte, A. John +13 more
2016Journal of Biological Chemistry37 citations Open access
Semantic Scholar
Role of mitogen-activated protein kinase and PI3K pathways in the regulation of IL-12-family cytokines in dendritic cells and the generation of T H-responses.
A. M. Jackson, Lori A. Mulcahy, J. Porte, H. Franks +5 more
2010European Cytokine Network35 citations
Semantic Scholar
Novel approach for interleukin‐23 up‐regulation in human dendritic cells and the impact on T helper type 17 generation
Qun-Wei Wang, H. Franks, J. Porte, Mohamed El Refaee +4 more
2011Immunology33 citations Open access
Semantic Scholar
Forced vital capacity trajectories in patients with idiopathic pulmonary fibrosis: a secondary analysis of a multicentre, prospective, observational cohort
H. Fainberg, J. Oldham, P. Molyneaux, R. Allen +17 more
2022The Lancet Digital Health30 citations Open access
Semantic Scholar
Loss of epithelial Gq and G11 signaling inhibits TGFβ production but promotes IL-33–mediated macrophage polarization and emphysema
A. John, M. R. Wilson, A. Habgood, J. Porte +8 more
2016Science Signaling27 citations Open access
Semantic Scholar
Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary fibrosis
A. Habgood, Amanda L. Tatler, J. Porte, S. Wahl +4 more
2016Laboratory Investigation26 citations Open access
Semantic Scholar
S31 The novel coronavirus SARS-CoV-2 binds RGD integrins and upregulates avb3 integrins in Covid-19 infected lungs
J. Calver, C. Joseph, A. John, L. Organ +11 more
202120 citations Open access
Semantic Scholar
Saliva for COVID-19 Testing: Simple but Useless or an Undervalued Resource?
S. Pijuan-Galitó, F. Tarantini, Hannah Tomlin, H. Jenkins +29 more
2021Frontiers in Virology16 citations Open access
Semantic Scholar
The IL-33:ST2 axis is unlikely to play a central fibrogenic role in idiopathic pulmonary fibrosis
K. Stephenson, J. Porte, A. Kelly, W. Wallace +5 more
2023Respiratory Research15 citations Open access
Semantic Scholar
Assessment of the effect of potential antifibrotic compounds on total and αVβ6 integrin‐mediated TGF‐β activation
J. Porte, G. Jenkins
2014Pharmacology Research & Perspectives14 citations Open access
Semantic Scholar
Investigating lung responses with functional hyperpolarized xenon‐129 MRI in an ex vivo rat model of asthma
D. Lilburn, Amanda L. Tatler, Joseph S. Six, Clémentine Lesbats +6 more
2015Magnetic Resonance in Medicine12 citations Open access
Semantic Scholar
Myofibroblast TGF-β Activation Measurement In Vitro.
J. Porte, G. Jenkins, Amanda L. Tatler
2021Methods in molecular biology10 citations
Semantic Scholar
Lysophosphatidic Acid Induces (cid:1) v (cid:2) 6 Integrin-Mediated TGF- (cid:2) Activation via the LPA2 Receptor and the Small G Protein G (cid:1) q
Ming-Yan Xu, J. Porte, A. Knox, P. Weinreb +5 more
20094 citations
Semantic Scholar
Methods for the Assessment of Active Transforming Growth Factor-β in Cells and Tissues.
A. John, J. Porte, G. Jenkins, Amanda L. Tatler
2017Methods in molecular biology3 citations Open access
Semantic Scholar
Investigating the role of AKAP13 on epithelial cell TGFß activation
L. Organ, J. Porte, A. John, G. Jenkins
2019Mechanisms of lung injury and repair1 citations
Semantic Scholar
S91 Investigating the role of AKAP13 in epithelial cells on TGF-β activation
Louise A. Organ, J. Porte, Alison E. John, R. Jenkins
2019Modelling lung disease in vitro/vivo1 citations
Semantic Scholar
Analysis of Forced Vital Capacity (FVC) Trajectories in Idiopathic Pulmonary Fibrosis (IPF) Identifies Four Distinct Clusters of Disease Behaviour
H. Fainberg, R. Allen, L. Kraven, P. Molyneaux +15 more
2022C70. NEW STUDIES OF LUNG FIBROSIS0 citations
Semantic Scholar
Binding of SARS-CoV-2 to the avb6 Integrins May Promote Severe COVID in Patients with IPF
C. Joseph, T. Peacock, J. Calver, A. John +13 more
2021TP105. TP105 BASIC MECHANISMS OF LUNG INFECTIONS: FROM SARS-COV-2 TO INFLUENZA0 citations
Semantic Scholar
Edinburgh Research Explorer Reduced Ets domain-containing protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin v6 Expression
Amanda L. Tatler, A. Habgood, J. Porte, A. John +16 more
20180 citations
Semantic Scholar
1 αvβ 6 integrin may be a potential prognostic biomarker in Interstitial Lung Disease
Gauri Saini, J. Porte, P. Weinreb, S. Violette +4 more
20170 citations
Semantic Scholar
αvβ6 integrin may be a potential prognostic biomarker in interstitial lung disease. European Respiratory Journal, (2).
Gauri Saini, J. Porte, P. Weinreb, S. Violette +4 more
20170 citations
Semantic Scholar
Reduction in colposcopy workload and associated clinical activity following HPV catch-up vaccination programme in Scotland: an ecological study
Amanda L. Tatler, A. Habgood, J. Porte, A. John +16 more
20160 citations
Semantic Scholar
Influenza-Induced Collagen Deposition And Peribronchial Fibrosis Occurs Independent Of Gq/11-Mediated Tgf beta Generation In The Alveolar Epithelium
A. John, A. Habgood, Amanda L. Tatler, J. Porte +2 more
20160 citations
Semantic Scholar
LSC 2014 abstract - Influenza infection may cause exacerbation of lung fibrosis through collagen deposition
A. Stavrou, L. Jolly, Nicholas Glanville, A. Habgood +5 more
2014European Respiratory Journal0 citations
Semantic Scholar
A Critical Role for Elk1 in Repression of avb6 Integrins and Pulmonary Fibrosis
Amanda L. Tatler, J. Porte, A. Habgood, Emily K. Hodge +12 more
20140 citations
Semantic Scholar
Epithelial Gq/11 signalling maintains alveolar homeostasis via the coordinated regulation of both TGF beta activation and IL-33 production in the lung
A. John, Amanda L. Tatler, J. Porte, A. Habgood +4 more
20140 citations
Semantic Scholar
Targeted Deletion Of The ±-Subunits Of G-Proteins Gq/G11 In Surfactant Protein C-Positive Epithelial Cells Results In Reduced TGF² Activation, Inflammation And Alveolar Airspace Enlargement
A. John, A. Habgood, J. Porte, Amanda L. Tatler +3 more
2012Asian Test Symposium0 citations
Semantic Scholar
S69 Transcriptional Mechanisms Regulating Expression of the Avb6 Integrin in IPF
A. Tatler, G. Saini, A. Goodwin, O. Gbolohan +11 more
2012Thorax0 citations Open access
Semantic Scholar
TGF-β Regulates αVβ6 Expression In Lung Epithelial Cells Via An Autocrine Loop Involving Smad3 But Not Smad2
Amanda L. Tatler, T. Beggah, Amanda T. Goodwin, O. Gbolohan +8 more
2012Asian Test Symposium0 citations
Semantic Scholar
Loss/inhibition of aVb5 integrin reduces allergen-induced increases in airway smooth muscle thickness in in vivo models of asthma
Amanda L. Tatler, A. John, A. Habgood, J. Porte +5 more
20110 citations
Semantic Scholar
Influenza A Activates Latent Transforming Growth Factor Beta (TGFBeta) Via Toll-Like Receptor 3 (TLR3) In A Process Involving AlphaVBeta6 Integrin
L. Jolly, J. Porte, P. Weinreb, S. Violette +5 more
2011Asian Test Symposium0 citations
Semantic Scholar
Transcriptional Regulation Of Integrin Beta6 Subunit By Transforming Growth Factor-Beta Via Smad2 And Smad4
Amanda L. Tatler, O. Gbolohan, Amanda T. Goodwin, Rachel L. Clifford +6 more
2011Asian Test Symposium0 citations
Semantic Scholar
S110 Targeted deletion of Gαq/Gα11 in surfactant protein C-positive epithelial cells reduces TGFß activation and results in inflammation and alveolar airspace enlargement
Alison E. John, A. Habgood, J. Porte, Amanda L. Tatler +3 more
2011Thorax0 citations Open access
Semantic Scholar
Targeted Deletion Of The Alpha Subunits Of G Proteins Gq/G11 But Not G12/13, In Surfactant Protein C-Positive Epithelial Cells Results In Mononuclear Inflammation And Alveolar Airspace Enlargement
A. John, J. Porte, L. Jolly, Amanda L. Tatler +2 more
2011Asian Test Symposium0 citations
Semantic Scholar
This information is current as Airway Smooth Muscle Cells in Asthma Activation by β 5-Mediated TGF-β v α Integrin
Pang, D. Sheppard, Xiao-Zhu Huang, G. Jenkins +8 more
20110 citations
Semantic Scholar
S32 Loss/inhibition of the aVb5 integrin reduces allergen-induced increases in airway smooth muscle mass in in vivo models of asthma
Amanda L. Tatler, Alison E. John, L. Jolly, A. Habgood +5 more
2011Thorax0 citations Open access
Semantic Scholar
S113 The influenza virus activates TGFß via an αVß6-integrin mediated pathway
A. Stavrou, L. Jolly, J. Porte, P. Weinreb +8 more
2011Thorax0 citations Open access
Semantic Scholar
S123 Mononuclear inflammation and disruption of normal alveolar structure following deletion of Gαq/11, but not Gα12/13, in type II alveolar epithelial cells
A. John, J. Porte, L. Jolly, Amanda L. Tatler +1 more
2010Thorax0 citations Open access
Semantic Scholar
Activation Of Transforming Growth Factor-² (TGF-²) In Response To Lysophosphatidic Acid Is Increased In Asthma
Amanda L. Tatler, A. John, L. Jolly, C. Brightling +4 more
2010Asian Test Symposium0 citations
Semantic Scholar
Activation of Transforming Growth Factor-β by Human Airway Smooth Muscle Cells Via αvβ5 Integrin.
Amanda L. Tatler, Ming-Yan Xu, J. Porte, A. Knox +2 more
2009Asian Test Symposium0 citations
Semantic Scholar

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