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R. Koenen · SciRah

Researcher profile · Semantic Scholar

R. Koenen

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R. Koenen — researcher profile on SciRah

h-index: 50
Works: 151
Citations: 9,502

Most-cited papers

MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages.
M. Nazari-Jahantigh, Yuan-Yuan Wei, H. Noels, Shamima Akhtar +8 more
2012Journal of Clinical Investigation529 citations Open access
Semantic Scholar
Auto-Antigenic Protein-DNA Complexes Stimulate Plasmacytoid Dendritic Cells to Promote Atherosclerosis
Y. Döring, H. Manthey, M. Drechsler, D. Lievens +12 more
2012Circulation429 citations Open access
Semantic Scholar
Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies
B. Benedikter, Freek G. Bouwman, T. Vajen, A. Heinzmann +8 more
2017Scientific Reports292 citations Open access
Semantic Scholar
Disruption of platelet-derived chemokine heteromers prevents neutrophil extravasation in acute lung injury.
J. Grommes, J. Alard, M. Drechsler, Sarawuth Wantha +11 more
2012American Journal of Respiratory and Critical Care Medicine237 citations Open access
Semantic Scholar
Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes
O. Soehnlein, M. Drechsler, Y. Döring, D. Lievens +12 more
2013EMBO Molecular Medicine216 citations Open access
Semantic Scholar
Extracellular Vesicles as Biomarkers in Cardiovascular Disease; Chances and Risks
Annemiek Dickhout, R. Koenen
2018Frontiers in Cardiovascular Medicine133 citations Open access
Semantic Scholar
Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation
P. von Hundelshausen, S. Agten, Veit Eckardt, X. Blanchet +24 more
2017Science Translational Medicine127 citations Open access
Semantic Scholar
Endothelial Junctional Adhesion Molecule-A Guides Monocytes Into Flow-Dependent Predilection Sites of Atherosclerosis
Martin M. N. Schmitt, R. Megens, A. Zernecke, K. Bidzhekov +6 more
2013Circulation124 citations Open access
Semantic Scholar
Touch of Chemokines
X. Blanchet, M. Langer, C. Weber, R. Koenen +1 more
2012Front. Immun.124 citations Open access
Semantic Scholar
Platelets: key players in vascular inflammation
Delia Projahn, R. Koenen
2012Journal of Leukocyte Biology117 citations Open access
Semantic Scholar
Chemokines as Therapeutic Targets in Cardiovascular Disease: The Road Behind, The Road Ahead
H. Noels, C. Weber, R. Koenen
2019Arteriosclerosis, Thrombosis and Vascular Biology111 citations Open access
Semantic Scholar
Platelet extracellular vesicles induce a pro-inflammatory smooth muscle cell phenotype
T. Vajen, B. Benedikter, A. Heinzmann, E. Vasina +7 more
2017Journal of Extracellular Vesicles109 citations Open access
Semantic Scholar
Microvesicles from platelets: novel drivers of vascular inflammation
T. Vajen, S. Mause, R. Koenen
2015Thrombosis and Haemostasis104 citations Open access
Semantic Scholar
Contribution of Platelet CX3CR1 to Platelet–Monocyte Complex Formation and Vascular Recruitment During Hyperlipidemia
O. Postea, E. Vasina, S. Cauwenberghs, Delia Projahn +10 more
2012Arteriosclerosis, Thrombosis and Vascular Biology90 citations Open access
Semantic Scholar
Translational opportunities of single-cell biology in atherosclerosis
M. de Winther, M. Bäck, Paul C. Evans, D. Gomez +13 more
2022European Heart Journal86 citations Open access
Semantic Scholar
Thrombo-Inflammation in Cardiovascular Disease: An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis
E. D'Alessandro, C. Becker, W. Bergmeier, C. Bode +70 more
2020Thrombosis and Haemostasis81 citations Open access
Semantic Scholar
Blocking CCL5-CXCL4 heteromerization preserves heart function after myocardial infarction by attenuating leukocyte recruitment and NETosis
T. Vajen, R. Koenen, I. Werner, M. Staudt +10 more
2018Scientific Reports80 citations Open access
Semantic Scholar
Initiation and Propagation of Vascular Calcification Is Regulated by a Concert of Platelet- and Smooth Muscle Cell-Derived Extracellular Vesicles
L. Schurgers, A. Akbulut, Dawid M Kaczor, Maurice Halder +2 more
2018Frontiers in Cardiovascular Medicine79 citations Open access
Semantic Scholar
The prowess of platelets in immunity and inflammation
R. Koenen
2016Thrombosis and Haemostasis79 citations
Semantic Scholar
Hyperreactivity of Junctional Adhesion Molecule A-Deficient Platelets Accelerates Atherosclerosis in Hyperlipidemic Mice
E. Karshovska, Zhen Zhao, X. Blanchet, Martin M. N. Schmitt +11 more
2015Circulation Research78 citations Open access
Semantic Scholar
CXCR4 blockade induces atherosclerosis by affecting neutrophil function
I. Bot, I. Daissormont, A. Zernecke, G. V. van Puijvelde +18 more
2014Journal of Molecular and Cellular Cardiology67 citations Open access
Semantic Scholar
Activation of CXCR7 Limits Atherosclerosis and Improves Hyperlipidemia by Increasing Cholesterol Uptake in Adipose Tissue
Xiaofeng Li, Meng-Yu Zhu, M. Penfold, R. Koenen +11 more
2014Circulation65 citations Open access
Semantic Scholar
Aging- and activation-induced platelet microparticles suppress apoptosis in monocytic cells and differentially signal to proinflammatory mediator release.
E. Vasina, S. Cauwenberghs, M. Staudt, M. Feijge +3 more
2013American Journal of Blood Research58 citations
Semantic Scholar
Hematopoietic Interferon Regulatory Factor 8-Deficiency Accelerates Atherosclerosis in Mice
Y. Döring, O. Soehnlein, M. Drechsler, E. Shagdarsuren +9 more
2012Arteriosclerosis, Thrombosis and Vascular Biology56 citations Open access
Semantic Scholar
Roadmap for alleviating the manifestations of ageing in the cardiovascular system
L. Liberale, Simon Tual-Chalot, S. Sedej, S. Ministrini +57 more
2025Nature Reviews Cardiology54 citations Open access
Semantic Scholar
Unveiling cellular and molecular aspects of ascending thoracic aortic aneurysms and dissections
Berta H Ganizada, R. Veltrop, A. Akbulut, R. Koenen +6 more
2024Basic Research in Cardiology51 citations Open access
Semantic Scholar
Atherothrombosis and Thromboembolism: Position Paper from the Second Maastricht Consensus Conference on Thrombosis
H. Spronk, T. Padró, J. Siland, J. Prochaska +59 more
2018Thrombosis and Haemostasis49 citations Open access
Semantic Scholar
Inflammatory role and prognostic value of platelet chemokines in acute coronary syndrome
X. Blanchet, Katja Cesarek, J. Brandt, H. Herwald +10 more
2014Thrombosis and Haemostasis44 citations
Semantic Scholar
The multifaceted contribution of platelets in the emergence and aftermath of acute cardiovascular events.
D. Coenen, A. Heinzmann, M. Karel, J. Cosemans +1 more
2021Atherosclerosis43 citations Open access
Semantic Scholar
Proteomic analysis reveals procoagulant properties of cigarette smoke-induced extracellular vesicles
B. Benedikter, Freek G. Bouwman, A. Heinzmann, T. Vajen +8 more
2019Journal of Extracellular Vesicles42 citations Open access
Semantic Scholar
TNF‐α and IFN‐γ promote lymphocyte adhesion to endothelial junctional regions facilitating transendothelial migration
J. Jaczewska, Midhat H. Abdulreda, Chi Y. Yau, Martin M. N. Schmitt +6 more
2014Journal of Leukocyte Biology42 citations Open access
Semantic Scholar
Controlled intramyocardial release of engineered chemokines by biodegradable hydrogels as a treatment approach of myocardial infarction
Delia Projahn, S. Simsekyilmaz, Smriti Singh, I. Kanzler +11 more
2014Journal of Cellular and Molecular Medicine40 citations Open access
Semantic Scholar
Peptidase inhibitor 16 is a membrane-tethered regulator of chemerin processing in the myocardium.
M. Regn, B. Laggerbauer, C. Jentzsch, D. Ramanujam +7 more
2016Journal of Molecular and Cellular Cardiology37 citations Open access
Semantic Scholar
Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque Motility
Indira Medina, C. Cougoule, M. Drechsler, B. Bermúdez +16 more
2015Circulation34 citations Open access
Semantic Scholar
Molecular Ultrasound Imaging of Junctional Adhesion Molecule A Depicts Acute Alterations in Blood Flow and Early Endothelial Dysregulation
Adelina Curaj, Zhuojun Wu, A. Rix, Oliver Gresch +8 more
2018Arteriosclerosis, Thrombosis and Vascular Biology33 citations Open access
Semantic Scholar
CCR6 selectively promotes monocyte mediated inflammation and atherogenesis in mice
H. Manthey, C. Cochain, Stefanie Barnsteiner, E. Karshovska +8 more
2013Thrombosis and Haemostasis31 citations
Semantic Scholar
Tick saliva protein Evasin-3 modulates chemotaxis by disrupting CXCL8 interactions with glycosaminoglycans and CXCR2
S. S. Denisov, J. H. Ippel, A. Heinzmann, R. Koenen +4 more
2019Journal of Biological Chemistry23 citations Open access
Semantic Scholar
Deletion of junctional adhesion molecule A from platelets increases early‐stage neointima formation after wire injury in hyperlipidemic mice
Zhen Zhao, T. Vajen, E. Karshovska, Annemiek Dickhout +7 more
2017Journal of Cellular and Molecular Medicine23 citations Open access
Semantic Scholar
Differential Effects of Platelet Factor 4 (CXCL4) and Its Non-Allelic Variant (CXCL4L1) on Cultured Human Vascular Smooth Muscle Cells
Dawid M Kaczor, R. Kramann, T. Hackeng, L. Schurgers +1 more
2022International Journal of Molecular Sciences19 citations Open access
Semantic Scholar
Atherogenic mononuclear cell recruitment is facilitated by oxidized lipoprotein-induced endothelial junctional adhesion molecule-A redistribution.
Martin M. N. Schmitt, Line Fraemohs, T. Hackeng, C. Weber +1 more
2014Atherosclerosis19 citations
Semantic Scholar
Anti-inflammatory therapeutic approaches to reduce acute atherosclerotic complications.
I. Kanzler, E. Liehn, R. Koenen, C. Weber
2012Current Pharmaceutical Biotechnology19 citations
Semantic Scholar
Galectokines: The Promiscuous Relationship between Galectins and Cytokines
L. Sanjurjo, Esmee C Broekhuizen, R. Koenen, V. Thijssen
2022Biomolecules18 citations Open access
Semantic Scholar
JAM‐A is a multifaceted regulator in hepatic fibrogenesis, supporting LSEC integrity and stellate cell quiescence
Jonathan Frederik Brozat, E. Brandt, M. Stark, P. Fischer +12 more
2022Liver international (Print)17 citations Open access
Semantic Scholar
Heterocomplexes between the atypical chemokine MIF and the CXC-motif chemokine CXCL4L1 regulate inflammation and thrombus formation
Markus Brandhofer, A. Hoffmann, X. Blanchet, Elena Siminkovitch +28 more
2021Cellular and Molecular Life Sciences17 citations Open access
Semantic Scholar
Structural characterization of anti-CCL5 activity of the tick salivary protein evasin-4
S. S. Denisov, M. Ramírez-Escudero, A. Heinzmann, J. H. Ippel +5 more
2020Journal of Biological Chemistry17 citations Open access
Semantic Scholar
Exchange of extracellular domains of CCR1 and CCR5 reveals confined functions in CCL5-mediated cell recruitment
B. Kramp, R. Megens, A. Sarabi, S. Winkler +4 more
2013Thrombosis and Haemostasis17 citations
Semantic Scholar
Inhibition of Phosphodiesterase 3A by Cilostazol Dampens Proinflammatory Platelet Functions
D. Coenen, A. Heinzmann, S. Oggero, H. J. Albers +8 more
2021Cells16 citations Open access
Semantic Scholar
Complementary roles of platelet αIIbβ3 integrin, phosphatidylserine exposure and cytoskeletal rearrangement in the release of extracellular vesicles.
A. Heinzmann, M. Karel, D. Coenen, T. Vajen +7 more
2020Atherosclerosis16 citations Open access
Semantic Scholar
Protein arginine deiminase 4 inactivates tissue factor pathway inhibitor-alpha by enzymatic modification of functional arginine residues.
M. Thomassen, Bryan R. C. Bouwens, K. Wichapong, D. Suylen +3 more
2023Journal of Thrombosis and Haemostasis15 citations Open access
Semantic Scholar
Galectin-1 and platelet factor 4 (CXCL4) induce complementary platelet responses in vitro
Annemiek Dickhout, B. Tullemans, J. Heemskerk, V. Thijssen +2 more
2021PLoS ONE15 citations Open access
Semantic Scholar

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