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Freek G. Bouwman · SciRah

Researcher profile · Semantic Scholar

Freek G. Bouwman

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Freek G. Bouwman — researcher profile on SciRah

h-index: 34
Works: 129
Citations: 3,875

Most-cited papers

Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies
B. Benedikter, Freek G. Bouwman, T. Vajen, A. Heinzmann +8 more
2017Scientific Reports292 citations Open access
Semantic Scholar
The Circulating Inactive Form of Matrix Gla Protein (ucMGP) as a Biomarker for Cardiovascular Calcification
Ellen C. M. Cranenburg, C. Vermeer, R. Koos, M. Boumans +6 more
2008Journal of Vascular Research198 citations
Semantic Scholar
Generally detected proteins in comparative proteomics – A matter of cellular stress response?
Ping Wang, Freek G. Bouwman, E. C. M. Mariman
2009Proteomics174 citations
Semantic Scholar
Postprandial responses in hunger and satiety are associated with the rs9939609 single nucleotide polymorphism in FTO.
M. den Hoed, M. Westerterp-Plantenga, Freek G. Bouwman, E. Mariman +1 more
2009American Journal of Clinical Nutrition116 citations Open access
Semantic Scholar
Proteomics investigations of drug-induced hepatotoxicity in HepG2 cells.
A. Van Summeren, J. Renes, Freek G. Bouwman, J. Noben +3 more
2011Toxicological Sciences104 citations Open access
Semantic Scholar
Proteomic methodological recommendations for studies involving human plasma, platelets, and peripheral blood mononuclear cells.
B. de Roos, S. Duthie, A. C. Polley, F. Mulholland +7 more
2008Journal of Proteome Research78 citations Open access
Semantic Scholar
Metabolomics of prolonged fasting in humans reveals new catabolic markers
I. Rubio-Aliaga, B. de Roos, S. Duthie, L. Crosley +18 more
2010Metabolomics71 citations
Semantic Scholar
Identification of novel human adipocyte secreted proteins by using SGBS cells.
A. Rosenow, T. Arrey, Freek G. Bouwman, J. Noben +4 more
2010Journal of Proteome Research67 citations
Semantic Scholar
The physiologic effects of caloric restriction are reflected in the in vivo adipocyte-enriched proteome of overweight/obese subjects.
Freek G. Bouwman, M. Claessens, M. V. van Baak, J. Noben +3 more
2009Journal of Proteome Research61 citations
Semantic Scholar
Rutin protects against H2O2-triggered impaired relaxation of placental arterioles and induces Nrf2-mediated adaptation in Human Umbilical Vein Endothelial Cells exposed to oxidative stress.
M. Sthijns, P. Schiffers, G. Janssen, K. Lemmens +9 more
2017Biochimica et Biophysica Acta - General Subjects57 citations
Semantic Scholar
PUFAs acutely affect triacylglycerol-derived skeletal muscle fatty acid uptake and increase postprandial insulin sensitivity.
A. Jans, E. Konings, G. Goossens, Freek G. Bouwman +6 more
2012American Journal of Clinical Nutrition51 citations Open access
Semantic Scholar
Associations between a single nucleotide polymorphism of the FTO Gene (rs9939609) and obesity-related characteristics over time during puberty in a Dutch children cohort.
F. Rutters, A. Nieuwenhuizen, Freek G. Bouwman, E. Mariman +1 more
2011Journal of Clinical Endocrinology and Metabolism50 citations Open access
Semantic Scholar
Identification and Characterization of Cardiac Troponin T Fragments in Serum of Patients Suffering from Acute Myocardial Infarction.
Alexander S. Streng, D. de Boer, W. V. van Doorn, Freek G. Bouwman +4 more
2017Clinical Chemistry45 citations Open access
Semantic Scholar
Variation in protein levels obtained from human blood cells and biofluids for platelet, peripheral blood mononuclear cell, plasma, urine and saliva proteomics
L. Crosley, S. Duthie, A. C. Polley, Freek G. Bouwman +8 more
2009Genes & Nutrition45 citations Open access
Semantic Scholar
Relationship between perilipin gene polymorphisms and body weight and body composition during weight loss and weight maintenance.
S. Soenen, E. Mariman, N. Vogels, Freek G. Bouwman +3 more
2009Physiology and Behavior44 citations
Semantic Scholar
Proteomic analysis reveals procoagulant properties of cigarette smoke-induced extracellular vesicles
B. Benedikter, Freek G. Bouwman, A. Heinzmann, T. Vajen +8 more
2019Journal of Extracellular Vesicles42 citations Open access
Semantic Scholar
The cilium: a cellular antenna with an influence on obesity risk
E. Mariman, Roel G. Vink, Nadia J. T. Roumans, Freek G. Bouwman +4 more
2016British Journal of Nutrition41 citations Open access
Semantic Scholar
Blood Profile of Proteins and Steroid Hormones Predicts Weight Change after Weight Loss with Interactions of Dietary Protein Level and Glycemic Index
Ping Wang, C. Holst, M. R. Andersen, A. Astrup +13 more
2011PLoS ONE40 citations Open access
Semantic Scholar
Differential expression of equine muscle biopsy proteins during normal training and intensified training in young standardbred horses using proteomics technology.
Freek G. Bouwman, M. V. van Ginneken, J. Noben, E. Royackers +5 more
2010Comparative Biochemistry and Physiology - Part D:Genomics and Proteomics34 citations
Semantic Scholar
Genetic predisposition, dietary restraint and disinhibition in relation to short and long-term weight loss.
S. P. Verhoef, S. G. Camps, Freek G. Bouwman, E. Mariman +1 more
2014Physiology and Behavior33 citations Open access
Semantic Scholar
2D-electrophoresis and multiplex immunoassay proteomic analysis of different body fluids and cellular components reveal known and novel markers for extended fasting
Freek G. Bouwman, B. de Roos, I. Rubio-Aliaga, L. Crosley +12 more
2011BMC Medical Genomics33 citations Open access
Semantic Scholar
Weight loss-induced cellular stress in subcutaneous adipose tissue and the risk for weight regain in overweight and obese adults
Nadia J. T. Roumans, Roel G. Vink, Freek G. Bouwman, Parastoo Fazelzadeh +2 more
2017International Journal of Obesity32 citations Open access
Semantic Scholar
Extreme obesity is associated with variation in genes related to the circadian rhythm of food intake and hypothalamic signaling.
E. Mariman, Freek G. Bouwman, E. Aller, M. V. van Baak +1 more
2015Physiological Genomics32 citations
Semantic Scholar
Cigarette smoke targets glutaredoxin 1, increasing s-glutathionylation and epithelial cell death.
I. Kuipers, Amy S. Guala, S. Aesif, G. Konings +5 more
2011American Journal of Respiratory Cell and Molecular Biology32 citations Open access
Semantic Scholar
Physiological Response of Adipocytes to Weight Loss and Maintenance
S. P. Verhoef, S. G. Camps, Freek G. Bouwman, E. Mariman +1 more
2013PLoS ONE30 citations Open access
Semantic Scholar
Genetic associations with acute stress-related changes in eating in the absence of hunger.
F. Rutters, S. Lemmens, Jurriaan M. Born, Freek G. Bouwman +3 more
2010Patient Education and Counseling30 citations
Semantic Scholar
Development of a targeted selected ion monitoring assay for the elucidation of protease induced structural changes in cardiac troponin T.
Alexander S. Streng, D. de Boer, Freek G. Bouwman, E. Mariman +3 more
2016Journal of Proteomics29 citations
Semantic Scholar
Heritability and genetic etiology of habitual physical activity: a twin study with objective measures
M. Gielen, M. Westerterp-Plantenga, Freek G. Bouwman, A. Joosen +5 more
2014Genes & Nutrition29 citations Open access
Semantic Scholar
Increased β‐oxidation with improved glucose uptake capacity in adipose tissue from obese after weight loss and maintenance
Freek G. Bouwman, Ping Wang, M. V. van Baak, W. H. Saris +1 more
2014Obesity29 citations Open access
Semantic Scholar
Insulin acutely upregulates protein expression of the fatty acid transporter CD36 in human skeletal muscle in vivo.
E. Corpeleijn, M. Pelsers, S. Soenen, M. Mensink +5 more
2008Journal of Physiology and Pharmacology29 citations
Semantic Scholar
The NuGO proof of principle study package: a collaborative research effort of the European Nutrigenomics Organisation
M. Baccini, Eva-Maria Bachmaier, A. Biggeri, M. Boekschoten +36 more
2008Genes & Nutrition28 citations Open access
Semantic Scholar
A comparison between the abdominal and femoral adipose tissue proteome of overweight and obese women
M. Vogel, Ping Wang, Freek G. Bouwman, Nicole T. H. Hoebers +4 more
2019Scientific Reports27 citations Open access
Semantic Scholar
SNP analyses of postprandial responses in (an)orexigenic hormones and feelings of hunger reveal long-term physiological adaptations to facilitate homeostasis
M. den Hoed, A. Smeets, M. Veldhorst, A. Nieuwenhuizen +5 more
2008International Journal of Obesity27 citations Open access
Semantic Scholar
The Role of Catechol-O-Methyl Transferase Val(108/158)Met Polymorphism (rs4680) in the Effect of Green Tea on Resting Energy Expenditure and Fat Oxidation: A Pilot Study
R. Hursel, P. Janssens, Freek G. Bouwman, E. Mariman +1 more
2014PLoS ONE24 citations Open access
Semantic Scholar
Plasma Levels of Triglycerides and IL-6 Are Associated With Weight Regain and Fat Mass Expansion
Q. Qiao, Freek G. Bouwman, M. V. van Baak, Nadia J. T. Roumans +2 more
2022Journal of Clinical Endocrinology and Metabolism23 citations Open access
Semantic Scholar
Brain tissue plasticity: protein synthesis rates of the human brain
J. Smeets, A. Horstman, O. Schijns, J. Dings +7 more
2018Brain : a journal of neurology23 citations
Semantic Scholar
Paternal Exposure to Environmental Chemical Stress Affects Male Offspring’s Hepatic Mitochondria
R. Godschalk, A. Remels, C. Hoogendoorn, J. van Benthem +9 more
2018Toxicological Sciences23 citations Open access
Semantic Scholar
Microbiota-Dependent Fiber Responses: A Proof-of-Concept Study on Short-Chain Fatty Acid Production in Prevotella- and Bacteroides-Dominated Healthy Individuals
M. Bartsch, M. Vital, Sabrina Woltemate, Freek G. Bouwman +3 more
2025Journal of NutriLife22 citations
Semantic Scholar
The Minor Structural Difference between the Antioxidants Quercetin and 4′O-Methylquercetin Has a Major Impact on Their Selective Thiol Toxicity
K. Lemmens, M. Vrolijk, Freek G. Bouwman, W. V. D. van der Vijgh +2 more
2014International Journal of Molecular Sciences22 citations Open access
Semantic Scholar
Screening for Drug-Induced Hepatotoxicity in Primary Mouse Hepatocytes Using Acetaminophen, Amiodarone, and Cyclosporin A as Model Compounds: An Omics-Guided Approach
A. Van Summeren, J. Renes, D. Lizárraga, Freek G. Bouwman +4 more
2013Omics22 citations Open access
Semantic Scholar
Butyrate and hexanoate-enriched triglycerides increase postprandrial systemic butyrate and hexanoate in men with overweight/obesity: A double-blind placebo-controlled randomized crossover trial
Thirza van Deuren, Lotte Smolders, A. Hartog, Freek G. Bouwman +4 more
2023Frontiers in Nutrition21 citations Open access
Semantic Scholar
Olfactory receptor genes cooperate with protocadherin genes in human extreme obesity
E. Mariman, R. Szklarczyk, Freek G. Bouwman, E. Aller +2 more
2015Genes & Nutrition19 citations Open access
Semantic Scholar
Hypoxia-mimetic effects in the secretome of human preadipocytes and adipocytes.
A. Rosenow, J. Noben, Freek G. Bouwman, E. Mariman +1 more
2013Biochimica et Biophysica Acta19 citations
Semantic Scholar
Blood profiling of proteins and steroids during weight maintenance with manipulation of dietary protein level and glycaemic index
Ping Wang, C. Holst, A. Astrup, Freek G. Bouwman +13 more
2011British Journal of Nutrition19 citations Open access
Semantic Scholar
The tobacco smoke component acrolein induces glucocorticoid resistant gene expression via inhibition of histone deacetylase
M. J. Randall, G. Haenen, Freek G. Bouwman, A. van der Vliet +1 more
2015Toxicology Letters18 citations Open access
Semantic Scholar
Weight loss-induced stress in subcutaneous adipose tissue is related to weight regain
Nadia J. T. Roumans, S. G. Camps, J. Renes, Freek G. Bouwman +2 more
2016British Journal of Nutrition17 citations Open access
Semantic Scholar
Leptin-adiposity relationship changes, plus behavioral and parental factors, are involved in the development of body weight in a Dutch children cohort.
F. Rutters, A. Nieuwenhuizen, N. Vogels, Freek G. Bouwman +2 more
2008Physiology and Behavior17 citations
Semantic Scholar
Heterogeneity of Lipid and Protein Cartilage Profiles Associated with Human Osteoarthritis with or without Type 2 Diabetes Mellitus
M. Eveque-Mourroux, P. Emans, A. Boonen, B. Claes +3 more
2021Journal of Proteome Research16 citations Open access
Semantic Scholar
Genetic Predictors of ≥5% Weight Loss by Multidisciplinary Advice to Severely Obese Subjects
E. Aller, E. Mariman, Freek G. Bouwman, Marleen A. van Baak
2017Lifestyle Genomics16 citations Open access
Semantic Scholar
Sex-specific effects of CNTF, IL6 and UCP2 polymorphisms on weight gain.
A. G. Heidema, Ping Wang, C. V. van Rossum, E. Feskens +4 more
2010Physiology and Behavior16 citations Open access
Semantic Scholar

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