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Fredrik Wångsell · SciRah

Researcher profile · Semantic Scholar

Fredrik Wångsell

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Fredrik Wångsell — researcher profile on SciRah

h-index: 10
Works: 16
Citations: 220

Most-cited papers

Use of a HEHEHE purification tag instead of a hexahistidine tag improves biodistribution of affibody molecules site-specifically labeled with (99m)Tc, (111)In, and (125)I.
C. Hofstrom, A. Orlova, M. Altai, Fredrik Wångsell +2 more
2011Journal of Medicinal Chemistry61 citations
Semantic Scholar
A3907, a systemic ASBT inhibitor, improves cholestasis in mice by multiorgan activity and shows translational relevance to humans
F. Caballero-Camino, P. Rodrigues, Fredrik Wångsell, Aloña Agirre-Lizaso +17 more
2023Hepatology34 citations Open access
Semantic Scholar
Novel potent macrocyclic inhibitors of the hepatitis C virus NS3 protease: use of cyclopentane and cyclopentene P2-motifs.
Marcus Bäck, Per-Ola Johansson, Fredrik Wångsell, F. Thorstensson +14 more
2007Bioorganic & Medicinal Chemistry28 citations Open access
Semantic Scholar
Synthesis of potent BACE-1 inhibitors incorporating a hydroxyethylene isostere as central core.
Fredrik Wångsell, K. Gustafsson, I. Kvarnström, N. Borkakoti +6 more
2010European journal of medicinal chemistry21 citations Open access
Semantic Scholar
Investigation of α-phenylnorstatine and α-benzylnorstatine as transition state isostere motifs in the search for new BACE-1 inhibitors.
Fredrik Wångsell, P. Nordeman, Jonas Sävmarker, R. Emanuelsson +5 more
2011Bioorganic & Medicinal Chemistry17 citations Open access
Semantic Scholar
Synthesis and labeling of a piperazine-based library of ¹¹C-labeled ligands for imaging of the vesicular acetylcholine transporter.
S. Bergman, Sergio Estrada, H. Hall, Rashidur Rahman +6 more
2014Journal of labelled compounds & radiopharmaceuticals13 citations
Semantic Scholar
Design and synthesis of BACE-1 inhibitors utilizing a tertiary hydroxyl motif as the transition state mimic.
Fredrik Wångsell, F. Russo, Jonas Sävmarker, Å. Rosenquist +2 more
2009Bioorganic & Medicinal Chemistry Letters13 citations Open access
Semantic Scholar
Synthesis and evaluation of a new class of tertiary alcohol based BACE-1 inhibitors
F. Russo, Fredrik Wångsell, Jonas Sävmarker, M. Jacobsson +1 more
200913 citations
Semantic Scholar
Radical Functionalization of Unsaturated Amino Acids: Synthesis of Side-Chain-Fluorinated, Azido-Substituted, and Hydroxylated Amino Acids
P. Reeve, U. Grabowska, Lourdes Salvador Oden, D. Wiktelius +2 more
2019ACS Omega10 citations Open access
Semantic Scholar
Synthesis of novel potent hepatitis C virus NS3 protease inhibitors: discovery of 4-hydroxy-cyclopent-2-ene-1,2-dicarboxylic acid as a N-acyl-L-hydroxyproline bioisostere.
F. Thorstensson, Fredrik Wångsell, I. Kvarnström, L. Vrang +5 more
2007Bioorganic & Medicinal Chemistry10 citations
Semantic Scholar
A3907, a systemic ASBT inhibitor, improves cholestasis in mice by inhibiting multi-organ bile acid transport and shows translational relevance to human
F. Caballero, P. Rodrigues, Aloña Agirre Lizaso, P. Olaizola +15 more
2023Journal of Hepatology0 citations
Semantic Scholar
Synthesis and biological evaluation of a piperazine-based library of C-11-Labeled PET tracers for imaging of the vesicular acetylcholine transporter
S. Bergman, A. Blomgren, H. Hall, M. Larhed +4 more
20130 citations
Semantic Scholar
Design and Synthesis of Aspartic and Serine Protease Inhibitors : Targeting the BACE-1 and the HCV NS3 Protease
Fredrik Wångsell
20090 citations
Semantic Scholar
Potent Macrocyclic Inhibitors of the Hepatitis C Virus NS3 Protease. Use of Cyclopentane and Cyclopentene Derived P2-Scaffolds
Marcus Bäck, Per-Ola Johansson, K. Jansson, L. Vrang +9 more
20070 citations
Semantic Scholar
Design and Synthesis of Serine and Aspartic Protease Inhibitors
Fredrik Wångsell
20060 citations
Semantic Scholar
Potent Macrocyclic Inhibitors of the Hepatitis C Virus NS3 Protease Incorporating Cyclopentane and Cyclopentene Derived Scaffolds
Marcus Bäck, Per-Ola Johansson, Fredrik Wångsell, F. Thorstensson +6 more
20060 citations
Semantic Scholar

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