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A. Herling · SciRah

Researcher profile · Semantic Scholar

A. Herling

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A. Herling — researcher profile on SciRah

h-index: 30
Works: 123
Citations: 3,117

Most-cited papers

Chlorogenic acid and synthetic chlorogenic acid derivatives: novel inhibitors of hepatic glucose-6-phosphate translocase.
H. Hemmerle, H. Burger, P. Below, G. Schubert +4 more
1997Journal of Medicinal Chemistry304 citations
Semantic Scholar
Chlorogenic acid and hydroxynitrobenzaldehyde: new inhibitors of hepatic glucose 6-phosphatase.
W. J. Arion, W. K. Canfield, Francisca Ramos, P. Schindler +5 more
1997Archives of Biochemistry and Biophysics273 citations Open access
Semantic Scholar
The cardiac K+ channel KCNQ1 is essential for gastric acid secretion.
Florian Grahammer, O. Wittekindt, R. Nitschke, A. Herling +5 more
2001Gastroenterology185 citations Open access
Semantic Scholar
Pharmacological profile of lixisenatide: A new GLP-1 receptor agonist for the treatment of type 2 diabetes.
U. Werner, G. Haschke, A. Herling, W. Kramer
2010Regulatory Peptides177 citations
Semantic Scholar
Intramyocellular lipid and insulin resistance: a longitudinal in vivo 1H-spectroscopic study in Zucker diabetic fatty rats.
Johanna Kuhlmann, C. Neumann‐Haefelin, Ulrich Belz, J. Kalisch +5 more
2003Diabetes141 citations
Semantic Scholar
Adenosine A1 receptors regulate lipolysis and lipogenesis in mouse adipose tissue-interactions with insulin.
Stina M. Johansson, E. Lindgren, Jiang Yang, A. Herling +1 more
2008European Journal of Pharmacology122 citations
Semantic Scholar
Acute Inhibition of Hepatic Glucose-6-phosphatase Does Not Affect Gluconeogenesis but Directs Gluconeogenic Flux toward Glycogen in Fasted Rats
T. V. van Dijk, F. H. van der Sluijs, C. Wiegman, J. Baller +6 more
2001Journal of Biological Chemistry109 citations Open access
Semantic Scholar
Increased energy expenditure contributes more to the body weight-reducing effect of rimonabant than reduced food intake in candy-fed wistar rats.
A. Herling, S. Kilp, R. Elvert, G. Haschke +1 more
2008Endocrinology101 citations
Semantic Scholar
Characterization of RA839, a Noncovalent Small Molecule Binder to Keap1 and Selective Activator of Nrf2 Signaling*
Angelika F. Winkel, C. Engel, D. Margerie, A. Kannt +11 more
2015Journal of Biological Chemistry91 citations Open access
Semantic Scholar
Guidelines for the care and use of laboratory animals
A. Herling, Jochen Maas, K. Seeger
199787 citations
Semantic Scholar
Acute inhibition of glucose-6-phosphate translocator activity leads to increased de novo lipogenesis and development of hepatic steatosis without affecting VLDL production in rats.
Robert H. J. Bandsma, C. Wiegman, A. Herling, H. Burger +5 more
2001Diabetes82 citations Open access
Semantic Scholar
Pharmacodynamic profile of a novel inhibitor of the hepatic glucose-6-phosphatase system.
A. Herling, H. Burger, D. Schwab, H. Hemmerle +2 more
1998American Journal of Physiology77 citations
Semantic Scholar
Chlorogenic acid analogue S 3483: a potent competitive inhibitor of the hepatic and renal glucose-6-phosphatase systems.
W. J. Arion, W. K. Canfield, Francisca Ramos, Mark L. Su +5 more
1998Archives of Biochemistry and Biophysics71 citations Open access
Semantic Scholar
Acyl ureas as human liver glycogen phosphorylase inhibitors for the treatment of type 2 diabetes.
T. Klabunde, K. Wendt, D. Kadereit, V. Brachvogel +9 more
2005Journal of Medicinal Chemistry69 citations Open access
Semantic Scholar
Alterations of carbohydrate and lipid intermediary metabolism during inhibition of glucose-6-phosphatase in rats.
A. Herling, H. Burger, G. Schubert, Horst Hemmerle +2 more
1999European Journal of Pharmacology63 citations
Semantic Scholar
Gene expression profiling in skeletal muscle of Zucker diabetic fatty rats: implications for a role of stearoyl-CoA desaturase 1 in insulin resistance
M. D. Voss, A. Beha, N. Tennagels, G. Tschank +6 more
2005Diabetologia62 citations Open access
Semantic Scholar
Characterization of adenosine-A1 receptor-mediated antilipolysis in rats by tissue microdialysis, 1H-spectroscopy, and glucose clamp studies.
C. Schoelch, Johanna Kuhlmann, M. Gossel, G. Mueller +7 more
2004Diabetes47 citations Open access
Semantic Scholar
Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists Specifically Optimized for Multidose Formulations.
A. Evers, M. Bossart, Stefania Pfeiffer-Marek, R. Elvert +12 more
2018Journal of Medicinal Chemistry42 citations Open access
Semantic Scholar
CB1 receptor antagonist AVE1625 affects primarily metabolic parameters independently of reduced food intake in Wistar rats.
A. Herling, M. Gossel, G. Haschke, S. Stengelin +4 more
2007American Journal of Physiology. Endocrinology and Metabolism42 citations
Semantic Scholar
AVE8134, a novel potent PPARα agonist, improves lipid profile and glucose metabolism in dyslipidemic mice and type 2 diabetic rats
Hans-Ludwig Schäfer, W. Linz, E. Falk, M. Glien +5 more
2012Acta Pharmacologica Sinica39 citations Open access
Semantic Scholar
Carbohydrate-response-element-binding protein (ChREBP) and not the liver X receptor α (LXRα) mediates elevated hepatic lipogenic gene expression in a mouse model of glycogen storage disease type 1.
A. Grefhorst, M. Schreurs, M. Oosterveer, V. Cortés +5 more
2010Biochemical Journal39 citations Open access
Semantic Scholar
Running on mixed fuel‐dual agonistic approach of GLP‐1 and GCG receptors leads to beneficial impact on body weight and blood glucose control: A comparative study between mice and non‐human primates
R. Elvert, A. Herling, M. Bossart, Tilo Weiss +13 more
2018Diabetes, obesity and metabolism38 citations Open access
Semantic Scholar
Dysregulated pyruvate dehydrogenase complex in Zucker diabetic fatty rats.
C. Schummer, U. Werner, N. Tennagels, D. Schmoll +6 more
2008American Journal of Physiology. Endocrinology and Metabolism36 citations
Semantic Scholar
Correlation between insulin resistance and intramyocellular lipid levels in rats
Johanna Kuhlmann, C. Neumann‐Haefelin, Ulrich Belz, W. Kramer +2 more
2005Magnetic Resonance in Medicine36 citations Open access
Semantic Scholar
Direct Evidence for the Involvement of Two Glucose 6-Phosphate-binding Sites in the Glucose-6-phosphatase Activity of Intact Liver Microsomes
W. J. Arion, W. K. Canfield, E. Callaway, H. Burger +4 more
1998Journal of Biological Chemistry36 citations Open access
Semantic Scholar
Appropriateness of the Zucker Diabetic Fatty rat as a model for diabetic microvascular late complications
J. Hempe, R. Elvert, H.-L. Schmidts, W. Kramer +1 more
2012Laboratory Animals. Journal of the Laboratory Animal Science Association35 citations
Semantic Scholar
The role of glucose 6‐phosphate in mediating the effects of glucokinase overexpression on hepatic glucose metabolism
Linda Härndahl, D. Schmoll, A. Herling, L. Agius
2006The FEBS Journal32 citations
Semantic Scholar
Leptin effect in ob/ob mice under thermoneutral conditions depends not necessarily on central satiation.
Johannes Rafael, A. Herling
2000American Journal of Physiology. Regulatory Integrative and Comparative Physiology31 citations
Semantic Scholar
Effects of AVE2268, a Substituted Glycopyranoside, on Urinary Glucose Excretion and Blood Glucose in Mice and Rats
M. Bickel, H. Brummerhop, W. Frick, H. Glombik +6 more
2008Arzneimittel-Forschung (Drug Research)30 citations
Semantic Scholar
Fatty acid and amino acid modulation of glucose cycling in isolated rat hepatocytes.
Lori A. Gustafson, Mies Neeft, D. Reijngoud, F. Kuipers +5 more
2001Biochemical Journal30 citations Open access
Semantic Scholar
Upregulation of hepatic glucose 6-phosphatase gene expression in rats treated with an inhibitor of glucose-6-phosphate translocase.
Caecilia Simon, A. Herling, Gerald Preibisch, H. Burger
2000Archives of Biochemistry and Biophysics29 citations
Semantic Scholar
Identification and synthesis of novel inhibitors of acetyl-CoA carboxylase with in vitro and in vivo efficacy on fat oxidation.
S. Keil, M. Müller, G. Zoller, G. Haschke +6 more
2010Journal of Medicinal Chemistry28 citations Open access
Semantic Scholar
Reversal of Inflammation‐Induced Impairment of Glucose Uptake in Adipocytes by Direct Effect of CB1 Antagonism on Adipose Tissue Macrophages
A. Miranville, A. Herling, G. Biemer-Daub, M. D. Voss
2010Obesity26 citations
Semantic Scholar
Reversal of visceral adiposity in candy-diet fed female Wistar rats by the CB1 receptor antagonist rimonabant
A. Herling, S. Kilp, H. Juretschke, C. Neumann‐Haefelin +2 more
2008International Journal of Obesity26 citations Open access
Semantic Scholar
Muscle type-specific fatty acid metabolism in insulin resistance: an integrated in vivo study in Zucker diabetic fatty rats.
A. Beha, H. Juretschke, Johanna Kuhlmann, C. Neumann‐Haefelin +5 more
2006American Journal of Physiology. Endocrinology and Metabolism26 citations
Semantic Scholar
Expression patterning reveals retinal inflammation as a minor factor in experimental retinopathy of ZDF rats
P. Wohlfart, Jihong Lin, N. Dietrich, A. Kannt +3 more
2014Acta Diabetologica24 citations Open access
Semantic Scholar
Muscle-type specific intramyocellular and hepatic lipid metabolism during starvation in wistar rats.
C. Neumann‐Haefelin, A. Beha, Johanna Kuhlmann, Ulrich Belz +11 more
2004Diabetes24 citations Open access
Semantic Scholar
Determinants of intramyocellular lipid concentrations in rat hindleg muscle
C. Neumann‐Haefelin, Johanna Kuhlmann, Ulrich Belz, J. Kalisch +4 more
2003Magnetic Resonance in Medicine23 citations Open access
Semantic Scholar
Team Players or Opponents: Coadministration of Selective Glucagon and GLP-1 Receptor Agonists in Obese Diabetic Monkeys.
R. Elvert, M. Bossart, A. Herling, Tilo Weiss +12 more
2018Endocrinology21 citations
Semantic Scholar
Hepatic uptake of synthetic chlorogenic acid derivatives by the organic anion transport proteins.
Dietmar Schwab, A. Herling, H. Hemmerle, G. Schubert +2 more
2001Journal of Pharmacology and Experimental Therapeutics20 citations
Semantic Scholar
Prolonged blood glucose reduction in mrp-2 deficient rats (GY/TR(-)) by the glucose-6-phosphate translocase inhibitor S 3025.
A. Herling, D. Schwab, H. Burger, Jochen Maas +7 more
2002Biochimica et Biophysica Acta17 citations
Semantic Scholar
Identification of two new inhibitors of the hepatic glucose‐6‐phosphatase system
P. Schindler, P. Below, H. Hemmerle, H. Burger +4 more
199816 citations
Semantic Scholar
The role of insulin resistance in experimental diabetic retinopathy—Genetic and molecular aspects
Patrick Järgen, A. Dietrich, A. Herling, H. Hammes +1 more
2017PLoS ONE15 citations Open access
Semantic Scholar
Profiling of Energy Metabolism in Olanzapine‐Induced Weight Gain in Rats and Its Prevention by the CB1‐Antagonist AVE1625
M. Liebig, M. Gossel, J. Pratt, M. Black +6 more
2010Obesity15 citations Open access
Semantic Scholar
A substituted thieno[3.4-d]imidazole versus substituted benzimidazoles as H+, K+-ATPase inhibitors.
A. Herling, M. Bickel, H. Lang, Klaus Weidmann +5 more
1988Pharmacology15 citations
Semantic Scholar
Effects of 3-mercaptopicolinic acid and a derivative of chlorogenic acid (S-3483) on hepatic and islet glucose-6-phosphatase activity.
Akhtar Khan, Zong-Chao Ling, Karin Pukk, A. Herling +2 more
1998European Journal of Pharmacology13 citations
Semantic Scholar
Gastric H+/K(+)-ATPase inhibitors.
A. Herling, Klaus Dr. Weidmann
1994Progress in Medicinal Chemistry13 citations
Semantic Scholar
Discovery and pharmacological characterization of SAR707 as novel and selective small molecule inhibitor of stearoyl-CoA desaturase (SCD1).
M. D. Voss, G. Zoller, H. Matter, A. Herling +6 more
2013European Journal of Pharmacology12 citations
Semantic Scholar
Energy loss via urine and faeces – a combustive analysis in diabetic rats and the impact of antidiabetic treatment on body weight
R. Elvert, A. Wille, J. Wandschneider, U. Werner +2 more
2013Diabetes, obesity and metabolism12 citations
Semantic Scholar
Stimulation of Fat Oxidation, but no Sustained Reduction of Hepatic Lipids by Prolonged Pharmacological Inhibition of Acetyl CoA Carboxylase
M. Glien, G. Haschke, K. Schroeter, A. Pfenninger +5 more
2011Hormone and Metabolic Research12 citations
Semantic Scholar

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