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G. Chew · SciRah

Researcher profile · Semantic Scholar

G. Chew

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G. Chew — researcher profile on SciRah

h-index: 14
Works: 40
Citations: 1,079

Most-cited papers

TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection
G. Chew, T. Fujita, G. Webb, B. Burwitz +17 more
2016PLoS Pathogens312 citations Open access
Semantic Scholar
T-cell immunoglobulin and mucin domain-containing protein 3 (Tim-3) is recruited to the immune synapse, disrupts stable synapse formation and associates with receptor phosphatases
K. Clayton, Matthew S. Haaland, M. Douglas-Vail, S. Mujib +3 more
2013Journal of Immunology127 citations Open access
Semantic Scholar
Soluble T Cell Immunoglobulin Mucin Domain 3 Is Shed from CD8+ T Cells by the Sheddase ADAM10, Is Increased in Plasma during Untreated HIV Infection, and Correlates with HIV Disease Progression
K. Clayton, M. Douglas-Vail, A. K. M. Nur-ur Rahman, Karyn E. Medcalf +8 more
2015Journal of Virology90 citations Open access
Semantic Scholar
Treatment intensification with maraviroc (CCR5 antagonist) leads to declines in CD16-expressing monocytes in cART-suppressed chronic HIV-infected subjects and is associated with improvements in neurocognitive test performance: implications for HIV-associated neurocognitive disease (HAND)
L. Ndhlovu, Tracie M Umaki, G. Chew, D. Chow +9 more
2014Journal of Neurovirology85 citations Open access
Semantic Scholar
Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation
M. Abdel-Mohsen, Leonard Chavez, R. Tandon, G. Chew +14 more
2015PLoS Pathogens75 citations Open access
Semantic Scholar
Galectin-9 Is Rapidly Released During Acute HIV-1 Infection and Remains Sustained at High Levels Despite Viral Suppression Even in Elite Controllers
R. Tandon, G. Chew, M. Byron, P. Borrow +8 more
2014AIDS Research and Human Retroviruses72 citations Open access
Semantic Scholar
Galectin-9 Plasma Levels Reflect Adverse Hamatological and Immunological Features in Acute Dengue Virus Infection
Haorile Chagan-Yasutan, L. Ndhlovu, T. L. Lacuesta, T. Kubo +10 more
2013Journal of Clinical Virology60 citations Open access
Semantic Scholar
Short Communication: Metformin Reduces CD4 T Cell Exhaustion in HIV-Infected Adults on Suppressive Antiretroviral Therapy
C. Shikuma, G. Chew, Lindsay B. Kohorn, Scott A. Souza +7 more
2019AIDS Research and Human Retroviruses29 citations Open access
Semantic Scholar
Expansion of Dysfunctional Tim-3 Expressing Effector Memory CD8+ T cells during SIV Infection in Rhesus Macaques
T. Fujita, B. Burwitz, G. Chew, J. Reed +10 more
2014Journal of Immunology29 citations Open access
Semantic Scholar
Mitochondrial oxidative phosphorylation in peripheral blood mononuclear cells is decreased in chronic HIV and correlates with immune dysregulation
L. M. Gangcuangco, B. Mitchell, Chathura Siriwardhana, Lindsay B. Kohorn +7 more
2020PLoS ONE24 citations Open access
Semantic Scholar
Siglec-9 defines and restrains a natural killer subpopulation highly cytotoxic to HIV-infected cells
Opeyemi S Adeniji, L. Kuri-Cervantes, Chen-Fei Yu, Ziyang Xu +13 more
2021PLoS Pathogens23 citations Open access
Semantic Scholar
HTLV-1 Tax Specific CD8+ T Cells Express Low Levels of Tim-3 in HTLV-1 Infection: Implications for Progression to Neurological Complications
L. Ndhlovu, F. Leal, Aaron M. Hasenkrug, A. Jha +14 more
2011PLoS Neglected Tropical Diseases23 citations Open access
Semantic Scholar
Antibody-based CCR5 blockade protects Macaques from mucosal SHIV transmission
Xiao-lin Chang, G. Webb, Helen L. Wu, Justin M. Greene +29 more
2021Nature Communications21 citations Open access
Semantic Scholar
Increased Frequency of Tim-3 Expressing T Cells Is Associated with Symptomatic West Nile Virus Infection
M. Lanteri, M. Diamond, Jacqueline P. Law, G. Chew +6 more
2014PLoS ONE20 citations Open access
Semantic Scholar
Phenotypic and Functional Analyses Guiding Combination Immune Checkpoint Immunotherapeutic Strategies in HTLV-1 Infection
Danielle M. Clements, Brenndan L. Crumley, G. Chew, Elijah Davis +4 more
2021Frontiers in Immunology14 citations Open access
Semantic Scholar
Red blood cell distribution width as an easily measurable biomarker of persistent inflammation and T cell dysregulation in antiretrovirally treated HIV-infected adults
Zao Zhang, G. Chew, C. Shikuma, L. M. Gangcuangco +9 more
2018HIV Clinical Trials13 citations Open access
Semantic Scholar
HTLV-1 infection and neuropathogenesis in the context of Rag1−/−γc−/− (RAG1-hu) and BLT mice
Rashida Ginwala, B. Caruso, Zafar K. Khan, A. Pattekar +7 more
2017Journal of Neuroimmune Pharmacology13 citations Open access
Semantic Scholar
Effects of Brief Adjunctive Metformin Therapy in Virologically Suppressed HIV-Infected Adults on Polyfunctional HIV-Specific CD8 T Cell Responses to PD-L1 Blockade
G. Chew, A. J. Padua, D. Chow, Scott A. Souza +7 more
2020AIDS Research and Human Retroviruses10 citations Open access
Semantic Scholar
Multi-antigen Vaccination With Simultaneous Engagement of the OX40 Receptor Delays Malignant Mesothelioma Growth and Increases Survival in Animal Models
P. Hoffmann, Fukun W. Hoffmann, T. Premeaux, T. Fujita +14 more
2019Frontiers in Oncology10 citations Open access
Semantic Scholar
Changes in gastrointestinal microbial communities influences HIV-specific CD8 T cell responsiveness to immune checkpoint blockade
I. SahBandar, G. Chew, M. Corley, A. Pang +10 more
2020AIDS (London)7 citations Open access
Semantic Scholar
PD-1+ and TIGIT+ CD4 T cells are associated with coronary artery calcium progression in HIV-infected treated adults
S. Bowler, G. Chew, M. Budoff, D. Chow +5 more
2019Journal of Acquired Immune Deficiency Syndromes6 citations Open access
Semantic Scholar
8th IAS Conference on HIV Pathogenesis, Treatment & Prevention 19–22 July 2015, Vancouver, Canada
Kelly A. Metcalf Pate, Christopher W. Pohlmeyer, Victoria Walker-Sperling, J. Foote +496 more
2015Journal of the International AIDS Society5 citations Open access
Semantic Scholar
Correction: Mitochondrial oxidative phosphorylation in peripheral blood mononuclear cells is decreased in chronic HIV and correlates with immune dysregulation
L. M. Gangcuangco, B. Mitchell, Chathura Siriwardhana, Lindsay B. Kohorn +7 more
2021PLoS ONE4 citations Open access
Semantic Scholar
Neurocognitive Trajectories After 72 Weeks of First-Line Anti-retroviral Therapy in Vietnamese Adults With HIV-HCV Co-infection
R. Paul, C. Shikuma, C. Nguyen, L. Ndhlovu +9 more
2021Frontiers in Neurology3 citations Open access
Semantic Scholar
1-1-2019 Multi-antigen Vaccination With Simultaneous Engagement of the OX 40 Receptor Delays Malignant Mesothelioma Growth and Increases Survival in Animal Models
P. Hoffmann, Fukun W. Hoffmann, T. Premeaux, T. Fujita +16 more
20192 citations
Semantic Scholar
HTLV-1 infection and neuropathogenesis in the context of Rag1−/−γc−/− (RAG1-hu) and BLT mice
Kiran Kumar Madagula, Rashida Ginwala, B. Caruso, Zafar K. Khan +8 more
2017Journal of Immunology2 citations Open access
Semantic Scholar
DNA Methylation Tightly Regulates TIGIT Expression in CD8+ T cells During Chronic HIV Infection
M. Corley, G. Chew, A. Pang, L. Ndhlovu
2020Journal of Immunology1 citations
Semantic Scholar
Immunologic Change over 72 Weeks Following Raltegravir- Versus Efavirenz-Based Therapy in HIV/HCV-Coinfected Individuals in Vietnam
C. Shikuma, Thuy Le, Thao Dao Vu Phuong, G. Chew +10 more
2021AIDS Research and Human Retroviruses0 citations Open access
Semantic Scholar
CD4+ T-cells expressing negative checkpoint receptors are associated with decreased mitochondrial oxidative phosphorylation in chronic HIV
L. M. Gangcuangco, C. Shikuma, B. Mitchell, S. Bowler +6 more
2019Journal of virus eradication0 citations Open access
Semantic Scholar
Role of the TIGIT Immune Checkpoint Pathway in the Eradication of HIV Infection.
G. Chew
20170 citations
Semantic Scholar
27 HIV-associated gastrointestinal microbial dysbiosis influences the efficacy of anti-HIV immunity by immune checkpoint blockade
I. SahBandar, G. Chew, M. Corley, A. Pang +7 more
20170 citations Open access
Semantic Scholar
Soluble Tim-3 is shed from CD8+ T cells by the sheddase ADAM10, is increased in plasma during untreated HIV infection, and correlates with HIV disease progression (VIR6P.1165)
K. Clayton, M. Douglas-Vail, A. Rahman, Karyn E. Medcalf +8 more
2015Journal of Immunology0 citations
Semantic Scholar
Characterization of human soluble Tim-3 and its role in HIV infection (VIR1P.1002)
K. Clayton, M. Douglas-Vail, Karyn E. Medcalf, G. Chew +3 more
2014Journal of Immunology0 citations
Semantic Scholar
Increased frequency of Tim-3+ T cells is associated with symptomatic WNV disease clinical outcome (P6085)
M. Lanteri, M. Diamond, J. Govero, Amelia K. Pinto +9 more
2013Journal of Immunology0 citations
Semantic Scholar
Rapid Galectin-9 release occurs following HIV-1 acquisition in acute HIV-1 infection (P6165)
R. Tandon, T. Fujita, G. Chew, M. Byron +11 more
2013Journal of Immunology0 citations
Semantic Scholar
and Associates with Receptor Phosphatases Synapse, Disrupts Stable Synapse Formation, Protein 3 Is Recruited to the Immune Containing - T Cell Ig and Mucin Domain
K. Clayton, Matthew S. Haaland, Matthew B. Douglas-Vail, Shariq Mujib +3 more
20130 citations
Semantic Scholar
Novel method for next generation sequencing of KIR by Roche 454 (P3383)
Bonnie Brayton, M. Byron, G. Chew, T. Tamate +2 more
2013Journal of Immunology0 citations
Semantic Scholar
KIR mediated natural killer cell function modified by Tim3 expression level in early untreated HIV infection (172.18)
Bonnie Brayton, T. Crawford, G. Chew, L. Ndhlovu +1 more
2012Journal of Immunology0 citations
Semantic Scholar
And Associates with Receptor Phosphatases Synapse, Disrupts Stable Synapse Formation, Protein 3 Is Recruited to the Immune Containing − T Cell Ig and Mucin Domain
Ndhlovu, M. Ostrowski, Douglas-Vail, S. Mujib +5 more
0 citations
Semantic Scholar

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