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C. E. van de Sandt · SciRah

Researcher profile · Semantic Scholar

C. E. van de Sandt

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C. E. van de Sandt — researcher profile on SciRah

h-index: 25
Works: 73
Citations: 3,161

Most-cited papers

Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19
I. Thevarajan, Thi H. O. Nguyen, M. Koutsakos, J. Druce +9 more
2020Nature Medicine1,026 citations Open access
Semantic Scholar
Back to the Future: Lessons Learned From the 1918 Influenza Pandemic
K. R. Short, K. Kedzierska, C. E. van de Sandt
2018Frontiers in Cellular and Infection Microbiology257 citations Open access
Semantic Scholar
Suboptimal SARS-CoV-2−specific CD8+ T cell response associated with the prominent HLA-A*02:01 phenotype
Jennifer R. Habel, Thi H. O. Nguyen, C. E. van de Sandt, J. Juno +21 more
2020Proceedings of the National Academy of Sciences of the United States of America185 citations Open access
Semantic Scholar
Systems serology detects functionally distinct coronavirus antibody features in children and elderly
K. Selva, C. E. van de Sandt, Melissa M. Lemke, Christina Y. Lee +37 more
2021Nature Communications157 citations Open access
Semantic Scholar
Integrated immune dynamics define correlates of COVID-19 severity and antibody responses
M. Koutsakos, L. Rowntree, L. Hensen, B. Chua +40 more
2021Cell Reports Medicine152 citations Open access
Semantic Scholar
CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope display high naive precursor frequency and TCR promiscuity
Thi H. O. Nguyen, L. Rowntree, J. Petersen, B. Chua +38 more
2021Immunity130 citations Open access
Semantic Scholar
Humoral responses after second and third SARS-CoV-2 vaccination in patients with immune-mediated inflammatory disorders on immunosuppressants: a cohort study
L. Wieske, K. V. van Dam, M. Steenhuis, E. Stalman +71 more
2022The Lancet Rheumatology114 citations Open access
Semantic Scholar
Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine
E. B. Clemens, C. E. van de Sandt, S. Wong, L. Wakim +1 more
2018Vaccines109 citations Open access
Semantic Scholar
Immune responses to SARS-CoV-2 in three children of parents with symptomatic COVID-19
S. Tosif, M. Neeland, P. Sutton, P. Licciardi +26 more
2020Nature Communications104 citations Open access
Semantic Scholar
Human Influenza A Virus-Specific CD8+ T-Cell Response Is Long-lived.
C. E. van de Sandt, M. Hillaire, M. M. Geelhoed-Mieras, A. Osterhaus +2 more
2015Journal of Infectious Diseases61 citations Open access
Semantic Scholar
Immune cellular networks underlying recovery from influenza virus infection in acute hospitalized patients
Thi H. O. Nguyen, M. Koutsakos, C. E. van de Sandt, J. Crawford +32 more
2021Nature Communications60 citations Open access
Semantic Scholar
SARS-CoV-2-specific T cell memory with common TCRαβ motifs is established in unvaccinated children who seroconvert after infection
L. Rowntree, T. H. Nguyen, Lukasz Kedzierski, M. Neeland +29 more
2022Immunity56 citations Open access
Semantic Scholar
Metabolic characteristics of CD8+ T cell subsets in young and aged individuals are not predictive of functionality
Kylie M. Quinn, Tabinda Hussain, Felix Kraus, L. E. Formosa +15 more
2020Nature Communications50 citations Open access
Semantic Scholar
Human CD8+ T Cells Damage Noninfected Epithelial Cells during Influenza Virus Infection In Vitro
C. E. van de Sandt, M. Bárcena, A. Koster, Jennifer Y. Kasper +7 more
2017American Journal of Respiratory Cell and Molecular Biology48 citations
Semantic Scholar
Influenza B virus-specific CD8+ T-lymphocytes strongly cross-react with viruses of the opposing influenza B lineage.
C. E. van de Sandt, Yingying Dou, Stella E. Vogelzang-van Trierum, K. Westgeest +5 more
2015Journal of General Virology48 citations Open access
Semantic Scholar
Breakthrough SARS-CoV-2 infections with the delta (B.1.617.2) variant in vaccinated patients with immune-mediated inflammatory diseases using immunosuppressants: a substudy of two prospective cohort studies
L. Boekel, E. Stalman, L. Wieske, F. Hooijberg +82 more
2022The Lancet Rheumatology43 citations Open access
Semantic Scholar
Human Mucosal-Associated Invariant T Cells in Older Individuals Display Expanded TCRαβ Clonotypes with Potent Antimicrobial Responses
L. Loh, N. Gherardin, S. Sant, L. Grzelak +17 more
2020Journal of Immunology42 citations Open access
Semantic Scholar
CD8+ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph
L. Hensen, P. Illing, E. B. Clemens, Thi H. O. Nguyen +32 more
2020Nature Communications42 citations Open access
Semantic Scholar
Newborn and child-like molecular signatures in older adults stem from TCR shifts across human lifespan
C. E. van de Sandt, Thi H. O. Nguyen, N. Gherardin, J. Crawford +32 more
2023Nature Immunology40 citations Open access
Semantic Scholar
Modified Vaccinia Virus Ankara Preferentially Targets Antigen Presenting Cells In Vitro, Ex Vivo and In Vivo
Arwen F Altenburg, C. E. van de Sandt, Bobby W. S. Li, R. Macloughlin +8 more
2017Scientific Reports37 citations Open access
Semantic Scholar
Distinct systems serology features in children, elderly and COVID patients
K. Selva, C. E. van de Sandt, Melissa M. Lemke, Christina Y. Lee +29 more
2020medRxiv36 citations Open access
Semantic Scholar
CD4^+ T cell calibration of antigen-presenting cells optimizes antiviral CD8^+ T cell immunity
E. Gressier, J. Schulte-Schrepping, Lev Petrov, S. Brumhard +38 more
2023Nature Immunology33 citations Open access
Semantic Scholar
Challenging immunodominance of influenza-specific CD8+ T cell responses restricted by the risk-associated HLA-A*68:01 allomorph
C. E. van de Sandt, E. B. Clemens, E. J. Grant, L. Rowntree +13 more
2019Nature Communications28 citations Open access
Semantic Scholar
High expression of oleoyl-ACP hydrolase underpins life-threatening respiratory viral diseases.
Xiao-Xiao Jia, J. Crawford, Deborah Gebregzabher, E. A. Monson +53 more
2024Cell27 citations Open access
Semantic Scholar
Robust correlations across six SARS‐CoV‐2 serology assays detecting distinct antibody features
L. Rowntree, B. Chua, S. Nicholson, M. Koutsakos +22 more
2021Clinical & Translational Immunology27 citations Open access
Semantic Scholar
Parallel detection of SARS‐CoV‐2 epitopes reveals dynamic immunodominance profiles of CD8 + T memory cells in convalescent COVID‐19 donors
J. van den Dijssel, R. Hagen, R. de Jongh, M. Steenhuis +12 more
2022Clinical & Translational Immunology21 citations Open access
Semantic Scholar
T Cell Epitope Discovery in the Context of Distinct and Unique Indigenous HLA Profiles
L. Hensen, P. Illing, L. Rowntree, J. Davies +8 more
2022Frontiers in Immunology19 citations Open access
Semantic Scholar
Immune profiling of SARS-CoV-2 infection during pregnancy reveals NK cell and γδ T cell perturbations
Jennifer R. Habel, B. Chua, L. Kedzierski, K. Selva +50 more
2023JCI Insight17 citations Open access
Semantic Scholar
Immune dynamics in SARS-CoV-2 experienced immunosuppressed rheumatoid arthritis or multiple sclerosis patients vaccinated with mRNA-1273
N. Verstegen, R. Hagen, J. van den Dijssel, L. Kuijper +25 more
2022eLife16 citations Open access
Semantic Scholar
Longitudinal T-Cell Responses After a Third SARS-CoV-2 Vaccination in Patients With Multiple Sclerosis on Ocrelizumab or Fingolimod
Virginia Palomares-Cabeza, L. Kummer, L. Wieske, R. Hagen +17 more
2022Neurology: Neuroimmunology & Neuroinflammation16 citations Open access
Semantic Scholar
HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8+ T cells
S. Sant, S. Quiñones-Parra, M. Koutsakos, E. Grant +10 more
2020PLoS Pathogens14 citations Open access
Semantic Scholar
CD8+ T-cell responses towards conserved influenza B virus epitopes across anatomical sites and age
Tejas Menon, P. Illing, P. Chaurasia, H. McQuilten +17 more
2024Nature Communications12 citations Open access
Semantic Scholar
Breadth of concomitant immune responses underpinning viral clearance and patient recovery in a non-severe case of COVID-19
I. Thevarajan, Thi H. O. Nguyen, M. Koutsakos, J. Druce +9 more
2020medRxiv12 citations Open access
Semantic Scholar
Divergent cytokine and transcriptional signatures control functional T follicular helper cell heterogeneity
Lennard Dalit, Chin-Wee Tan, Amania A. Sheikh, R. Munnings +23 more
2025Nature Immunology10 citations Open access
Semantic Scholar
mRNA-1273 vaccinated inflammatory bowel disease patients receiving TNF inhibitors develop broad and robust SARS-CoV-2-specific CD8+ T cell responses.
J. van den Dijssel, M. Duurland, Veronique Al Konijn, L. Kummer +25 more
2024Journal of Autoimmunity10 citations Open access
Semantic Scholar
Cutting Edge: SARS-CoV-2 Infection Induces Robust Germinal Center Activity in the Human Tonsil
Hyon-Xhi Tan, Kathleen M. Wragg, Hannah G. Kelly, R. Esterbauer +9 more
2022Journal of Immunology9 citations Open access
Semantic Scholar
Robust and prototypical immune responses toward influenza vaccines in the high-risk group of Indigenous Australians
L. Hensen, Thi H. O. Nguyen, L. Rowntree, Timon Damelang +25 more
2021Proceedings of the National Academy of Sciences of the United States of America9 citations Open access
Semantic Scholar
Distinct systems serology features in children, elderly and COVID patients
K. Selva, C. E. van de Sandt, Melissa M. Lemke, Christina Y. Lee +34 more
20209 citations
Semantic Scholar
Increased Protein Degradation Improves Influenza Virus Nucleoprotein-Specific CD8+ T Cell Activation In Vitro but Not in C57BL/6 Mice
Arwen F Altenburg, C. E. van de Sandt, S. E. van Trierum, Heidi L. M. de Gruyter +8 more
2016Journal of Virology8 citations Open access
Semantic Scholar
Gradual changes within long-lived influenza virus-specific CD8+ T cells are associated with the loss of public TCR clonotypes in older adults
C. E. van de Sandt, H. McQuilten, M. Aban, Thi H. O. Nguyen +7 more
2025EBioMedicine7 citations Open access
Semantic Scholar
H1N1pdm09 Influenza Virus and Its Descendants Lack Extra-epitopic Amino Acid Residues Associated With Reduced Recognition by M158-66-Specific CD8+ T Cells
C. E. van de Sandt, Kyung A Sagong, Mark R. Pronk, T. Bestebroer +4 more
2018Journal of Infectious Diseases7 citations Open access
Semantic Scholar
Effect of Bacille Calmette–Guérin vaccination on immune responses to SARS‐CoV‐2 and COVID‐19 vaccination
N. Messina, S. Germano, Amy W. Chung, C. E. van de Sandt +19 more
2025Clinical & Translational Immunology6 citations Open access
Semantic Scholar
Immunodominant responses to the influenza virus M158–66 epitope: Stealth or protection?
C. E. van de Sandt, G. Rimmelzwaan
2015Proceedings of the National Academy of Sciences of the United States of America6 citations Open access
Semantic Scholar
T cell activation markers CD38 and HLA-DR indicative of non-seroconversion in anti-CD20-treated patients with multiple sclerosis following SARS-CoV-2 mRNA vaccination
N. Verstegen, R. Hagen, Christine Kreher, L. Kuijper +25 more
2024Journal of Neurology Neurosurgery & Psychiatry5 citations Open access
Semantic Scholar
Variation at Extra-epitopic Amino Acid Residues Influences Suppression of Influenza Virus Replication by M158-66 Epitope-Specific CD8+ T Lymphocytes
C. E. van de Sandt, Mark R. Pronk, C. V. van Baalen, R. Fouchier +1 more
2018Journal of Virology5 citations Open access
Semantic Scholar
Central memory T cells with key TCR repertoires and gene expression profiles dominate influenza CD8+ T cell pools across the human lifespan
Tejas Menon, H. McQuilten, J. Samir, Thi H. O. Nguyen +14 more
2025Proceedings of the National Academy of Sciences of the United States of America4 citations Open access
Semantic Scholar
Methotrexate treatment hampers induction of vaccine-specific CD4 T cell responses in patients with IMID
L. Kummer, Laura Fernandez Blanco, Christine Kreher, A. Bos +26 more
2024RMD Open4 citations Open access
Semantic Scholar
Re: Integrated Immune Dynamics Define Correlates of COVID-19 Severity and Antibody Responses
M. Koutsakos, L. Rowntree, L. Hensen, B. Chua +37 more
2020Social Science Research Network4 citations
Semantic Scholar
Evolution of SARS-CoV-2 antibody repertoire after successive mRNA vaccinations under immunosuppressive treatment
J. Keijser, E. Stalman, L. Wieske, M. Steenhuis +72 more
2025EBioMedicine3 citations Open access
Semantic Scholar
High glycemic variability is associated with a reduced T cell cytokine response to influenza A virus
M. Tong, Katina D Hulme, S. Law, E. Noye +17 more
2024iScience3 citations Open access
Semantic Scholar

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