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B. Chua · SciRah

Researcher profile · Semantic Scholar

B. Chua

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B. Chua — researcher profile on SciRah

h-index: 29
Works: 105
Citations: 2,463

Most-cited papers

Human CD8+ T cell cross-reactivity across influenza A, B and C viruses
M. Koutsakos, P. Illing, Thi H. O. Nguyen, N. Mifsud +33 more
2019Nature Immunology221 citations Open access
Semantic Scholar
Suboptimal SARS-CoV-2−specific CD8+ T cell response associated with the prominent HLA-A*02:01 phenotype
Jennifer R. Habel, Thi H. O. Nguyen, C. E. van de Sandt, J. Juno +21 more
2020Proceedings of the National Academy of Sciences of the United States of America185 citations Open access
Semantic Scholar
Systems serology detects functionally distinct coronavirus antibody features in children and elderly
K. Selva, C. E. van de Sandt, Melissa M. Lemke, Christina Y. Lee +37 more
2021Nature Communications157 citations Open access
Semantic Scholar
Integrated immune dynamics define correlates of COVID-19 severity and antibody responses
M. Koutsakos, L. Rowntree, L. Hensen, B. Chua +40 more
2021Cell Reports Medicine152 citations Open access
Semantic Scholar
CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope display high naive precursor frequency and TCR promiscuity
Thi H. O. Nguyen, L. Rowntree, J. Petersen, B. Chua +38 more
2021Immunity130 citations Open access
Semantic Scholar
Chitosan microparticles and nanoparticles as biocompatible delivery vehicles for peptide and protein-based immunocontraceptive vaccines.
B. Chua, M. Al Kobaisi, Weiguang Zeng, D. Mainwaring +1 more
2012Molecular Pharmaceutics104 citations
Semantic Scholar
Prophylactic intranasal administration of a TLR2/6 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model
P. Proud, D. Tsitoura, Robert J. Watson, B. Chua +22 more
2020EBioMedicine88 citations Open access
Semantic Scholar
Recalling the Future: Immunological Memory Toward Unpredictable Influenza Viruses
Maria Auladell, Xiao-Xiao Jia, L. Hensen, B. Chua +4 more
2019Frontiers in Immunology72 citations Open access
Semantic Scholar
Hepatitis C VLPs Delivered to Dendritic Cells by a TLR2 Targeting Lipopeptide Results in Enhanced Antibody and Cell-Mediated Responses
B. Chua, Douglas F. Johnson, Amabel C. L. Tan, L. Earnest-Silveira +4 more
2012PLoS ONE57 citations Open access
Semantic Scholar
SARS-CoV-2-specific T cell memory with common TCRαβ motifs is established in unvaccinated children who seroconvert after infection
L. Rowntree, T. H. Nguyen, Lukasz Kedzierski, M. Neeland +29 more
2022Immunity56 citations Open access
Semantic Scholar
A self-adjuvanting lipopeptide-based vaccine candidate for the treatment of hepatitis C virus infection.
B. Chua, E. Eriksson, L. Brown, Weiguang Zeng +3 more
2008Vaccine55 citations Open access
Semantic Scholar
Defining the balance between optimal immunity and immunopathology in influenza virus infection
Thi H. O. Nguyen, L. Rowntree, B. Chua, R. Thwaites +1 more
2024Nature reviews. Immunology51 citations
Semantic Scholar
Soluble Proteins Induce Strong CD8+ T Cell and Antibody Responses through Electrostatic Association with Simple Cationic or Anionic Lipopeptides That Target TLR2
B. Chua, David Pejoski, S. Turner, Weiguang Zeng +1 more
2011Journal of Immunology44 citations Open access
Semantic Scholar
Immunological responses following administration of a genotype 1a/1b/2/3a quadrivalent HCV VLP vaccine
D. Christiansen, L. Earnest-Silveira, B. Chua, P. Meuleman +8 more
2018Scientific Reports43 citations Open access
Semantic Scholar
CD8+ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph
L. Hensen, P. Illing, E. B. Clemens, Thi H. O. Nguyen +32 more
2020Nature Communications42 citations Open access
Semantic Scholar
SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severity
Wu-Ji Zhang, B. Chua, K. Selva, L. Kedzierski +47 more
2022Nature Communications39 citations Open access
Semantic Scholar
Distinct systems serology features in children, elderly and COVID patients
K. Selva, C. E. van de Sandt, Melissa M. Lemke, Christina Y. Lee +29 more
2020medRxiv36 citations Open access
Semantic Scholar
Inactivated Influenza Vaccine That Provides Rapid, Innate-Immune-System-Mediated Protection and Subsequent Long-Term Adaptive Immunity
B. Chua, C. Y. Wong, Edin J. Mifsud, K. Edenborough +10 more
2015mBio34 citations Open access
Semantic Scholar
Structural requirement for the agonist activity of the TLR2 ligand Pam2Cys
Weiguang Zeng, E. Eriksson, B. Chua, L. Grollo +1 more
2010Amino Acids34 citations
Semantic Scholar
PEGylation of a TLR2-agonist-based vaccine delivery system improves antigen trafficking and the magnitude of ensuing antibody and CD8+ T cell responses.
Toshiki Sekiya, Junya Yamagishi, J. H. V. Gray, Paul G. Whitney +6 more
2017Biomaterials33 citations
Semantic Scholar
Characterization of a hepatitis C virus-like particle vaccine produced in a human hepatocyte-derived cell line.
L. Earnest-Silveira, B. Chua, R. Chin, D. Christiansen +13 more
2016Journal of General Virology33 citations Open access
Semantic Scholar
Oseltamivir Prophylaxis Reduces Inflammation and Facilitates Establishment of Cross-Strain Protective T Cell Memory to Influenza Viruses
Nicola L. Bird, Matthew R. Olson, A. Hurt, C. Oshansky +10 more
2015PLoS ONE33 citations Open access
Semantic Scholar
Control of size dispersity of chitosan biopolymer microparticles and nanoparticles to influence vaccine trafficking and cell uptake.
Mohammad Al Kobiasi, B. Chua, David Tonkin, D. Jackson +1 more
2012Journal of Biomedical Materials Research. Part A30 citations
Semantic Scholar
Synthesis of toll-like receptor-2 targeting lipopeptides as self-adjuvanting vaccines.
B. Chua, Weiguang Zeng, D. Jackson
2008Methods in molecular biology30 citations
Semantic Scholar
Robust and prototypical immune responses toward COVID-19 vaccine in First Nations peoples are impacted by comorbidities
Wu-Ji Zhang, L. Kedzierski, B. Chua, M. Mayo +42 more
2023Nature Immunology29 citations Open access
Semantic Scholar
TLR2-mediated innate immune priming boosts lung anti-viral immunity
J. Girkin, S. Loo, Camille Esneau, S. Maltby +10 more
2020European Respiratory Journal29 citations Open access
Semantic Scholar
The use of a TLR2 agonist‐based adjuvant for enhancing effector and memory CD8 T‐cell responses
B. Chua, Matthew R. Olson, S. Bedoui, Toshiki Sekiya +3 more
2014Immunology and Cell Biology29 citations
Semantic Scholar
High expression of oleoyl-ACP hydrolase underpins life-threatening respiratory viral diseases.
Xiao-Xiao Jia, J. Crawford, Deborah Gebregzabher, E. A. Monson +53 more
2024Cell27 citations Open access
Semantic Scholar
Robust correlations across six SARS‐CoV‐2 serology assays detecting distinct antibody features
L. Rowntree, B. Chua, S. Nicholson, M. Koutsakos +22 more
2021Clinical & Translational Immunology27 citations Open access
Semantic Scholar
A single dose biodegradable vaccine depot that induces persistently high levels of antibody over a year.
B. Chua, Toshiki Sekiya, M. Al Kobaisi, K. R. Short +2 more
2015Biomaterials27 citations
Semantic Scholar
TLR2-mediated activation of innate responses in the upper airways confers antiviral protection of the lungs
Georgia Deliyannis, C. Y. Wong, H. McQuilten, A. Bachem +15 more
2021JCI Insight26 citations Open access
Semantic Scholar
High expression of CD38 and MHC class II on CD8+ T cells during severe influenza disease reflects bystander activation and trogocytosis
Xiao-Xiao Jia, B. Chua, L. Loh, M. Koutsakos +7 more
2021bioRxiv24 citations Open access
Semantic Scholar
The impact of influenza pulmonary infection and inflammation on vagal bronchopulmonary sensory neurons
N. Verzele, B. Chua, C. Law, Albert Y Zhang +12 more
2021The FASEB Journal22 citations Open access
Semantic Scholar
Robust SARS-CoV-2 T cell responses with common TCRαβ motifs toward COVID-19 vaccines in patients with hematological malignancy impacting B cells
Thi H. O. Nguyen, L. Rowntree, L. Allen, B. Chua +51 more
2023Cell Reports Medicine21 citations Open access
Semantic Scholar
Opinion: Making Inactivated and Subunit-Based Vaccines Work
B. Chua, Toshiki Sekiya, D. Jackson
2018Viral immunology18 citations
Semantic Scholar
Reducing the impact of influenza‐associated secondary pneumococcal infections
Edin J. Mifsud, Amabel C. L. Tan, K. R. Short, L. Brown +2 more
2016Immunology and Cell Biology18 citations
Semantic Scholar
Immune profiling of SARS-CoV-2 infection during pregnancy reveals NK cell and γδ T cell perturbations
Jennifer R. Habel, B. Chua, L. Kedzierski, K. Selva +50 more
2023JCI Insight17 citations Open access
Semantic Scholar
The endogenous inflammatory reflex inhibits the inflammatory response to different immune challenges in mice.
A. Occhinegro, C. Y. Wong, B. Chua, D. C. Jackson +3 more
2021Brain, behavior, and immunity16 citations
Semantic Scholar
Vaccine-Specific Immune Responses against Mycobacterium ulcerans Infection in a Low-Dose Murine Challenge Model
Kirstie M. Mangas, Andrew H. Buultjens, J. Porter, S. Baines +11 more
2019Infection and Immunity16 citations Open access
Semantic Scholar
Establishment of memory CD8+ T cells with live attenuated influenza virus across different vaccination doses.
Zhong-Fang Wang, L. Kedzierski, Simone Nuessing, B. Chua +5 more
2016Journal of General Virology16 citations Open access
Semantic Scholar
Potent priming by inactivated whole influenza virus particle vaccines is linked to viral RNA uptake into antigen presenting cells.
M. Shingai, Naoki Nomura, Toshiki Sekiya, Marumi Ohno +27 more
2021Vaccine13 citations Open access
Semantic Scholar
Dendritic cell acquisition of epitope cargo mediated by simple cationic peptide structures.
B. Chua, E. Eriksson, D. Poole, Weiguang Zeng +1 more
2008Peptides12 citations
Semantic Scholar
Antibody Responses to a Quadrivalent Hepatitis C Viral-Like Particle Vaccine Adjuvanted with Toll-Like Receptor 2 Agonists
D. Christiansen, L. Earnest-Silveira, B. Chua, I. Boo +5 more
2018Viral immunology11 citations
Semantic Scholar
Competition within the virus‐specific CD4 T‐cell pool limits the T follicular helper response after influenza infection
Matthew R. Olson, B. Chua, K. Good-Jacobson, P. Doherty +2 more
2016Immunology and Cell Biology11 citations
Semantic Scholar
Generation of Adaptive Immune Responses Following Influenza Virus Challenge is Not Compromised by Pre-Treatment with the TLR-2 Agonist Pam2Cys
Edin J. Mifsud, Amabel C. L. Tan, L. Brown, B. Chua +1 more
2015Frontiers in Immunology11 citations Open access
Semantic Scholar
The Toll-Like Receptor 2 agonist PEG-Pam2Cys as an immunochemoprophylactic and immunochemotherapeutic against the liver and transmission stages of malaria parasites
M. Ernest, Carol W. Hunja, Yuka Arakura, Yohei Haraga +5 more
2018International Journal for Parasitology: Drugs and Drug Resistance10 citations Open access
Semantic Scholar
Structure–function relationships of protein–lipopeptide complexes and influence on immunogenicity
A. R. Wijayadikusumah, L. Sullivan, D. Jackson, B. Chua
2017Amino Acids10 citations Open access
Semantic Scholar
Establishment of functional influenza virus-specific CD8(+) T cell memory pools after intramuscular immunization.
Zhong-Fang Wang, B. Chua, Javier Vega Ramos, Sergio M. Quiñones Parra +4 more
2015Vaccine10 citations
Semantic Scholar
Prior infection with unrelated neurotropic virus exacerbates influenza disease and impairs lung T cell responses
I. J. Foo, B. Chua, E. B. Clemens, So-young Chang +13 more
2024Nature Communications9 citations Open access
Semantic Scholar
Evidence for vagal sensory neural involvement in influenza pathogenesis and disease
N. Verzele, B. Chua, Kirsty R. Short, Aung Aung Kywe Moe +9 more
2023bioRxiv9 citations Open access
Semantic Scholar

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