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M. Dirain · SciRah

Researcher profile · Semantic Scholar

M. Dirain

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M. Dirain — researcher profile on SciRah

h-index: 20
Works: 39
Citations: 1,322

Most-cited papers

Blood Flow Restriction Enhances Post–Resistance Exercise Angiogenic Gene Expression
Kelly A. Larkin, R. MacNeil, M. Dirain, Bhanupresad Sandesara +2 more
2012Medicine & Science in Sports & Exercise162 citations Open access
Semantic Scholar
EVIDENCE FOR PERSISTENT IMMUNE SUPPRESSION IN PATIENTS WHO DEVELOP CHRONIC CRITICAL ILLNESS AFTER SEPSIS
Julie A. Stortz, Tyler J Murphy, Steven L. Raymond, Juan C. Mira +14 more
2017Shock134 citations Open access
Semantic Scholar
Caprylic acid supplemented in feed reduces enteric Campylobacter jejuni colonization in ten-day-old broiler chickens.
F. S. de los Santos, A. Donoghue, K. Venkitanarayanan, M. Dirain +3 more
2008Poultry Science106 citations Open access
Semantic Scholar
Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis
Mckenzie Hollen, Julie A. Stortz, D. Darden, M. Dirain +20 more
2019Critical Care99 citations Open access
Semantic Scholar
Calorie restriction combined with resveratrol induces autophagy and protects 26-month-old rat hearts from doxorubicin-induced toxicity
D. Dutta, Jin-Ze Xu, M. Dirain, C. Leeuwenburgh
2014Free Radical Biology & Medicine95 citations Open access
Semantic Scholar
The natural feed additive caprylic acid decreases Campylobacter jejuni colonization in market-aged broiler chickens.
F. Solís de los Santos, A. Donoghue, K. Venkitanarayanan, J. Metcalf +5 more
2009Poultry Science87 citations Open access
Semantic Scholar
Pharmacological Characterization of 30 Human Melanocortin-4 Receptor Polymorphisms with the Endogenous Proopiomelanocortin Derived Agonists, Synthetic Agonists, and the Endogenous Agouti-Related Protein (AGRP) Antagonist
Zhi-Min Xiang, Bettina Proneth, M. Dirain, S. Litherland +1 more
2010Biochemistry61 citations Open access
Semantic Scholar
A Novel Single Cell RNA-seq Analysis of Non-Myeloid Circulating Cells in Late Sepsis
D. Darden, Xiaoru Dong, Maigan A. Brusko, Lauren S. Kelly +15 more
2021Frontiers in Immunology57 citations Open access
Semantic Scholar
Single Cell RNA-seq of Human Myeloid Derived Suppressor Cells in Late Sepsis Reveals Multiple Subsets with Unique Transcriptional Responses: A Pilot Study
D. Darden, Rhonda L. Bacher, Maigan A. Brusko, Parker Knight +15 more
2020Shock52 citations Open access
Semantic Scholar
Therapeutic Supplementation of Caprylic Acid in Feed Reduces Campylobacter jejuni Colonization in Broiler Chicks
F. Solís de los Santos, A. Donoghue, K. Venkitanarayanan, I. Reyes-Herrera +5 more
2008Applied and Environmental Microbiology44 citations Open access
Semantic Scholar
The effect of backbone cyclization on PK/PD properties of bioactive peptide-peptoid hybrids: the melanocortin agonist paradigm.
O. Ovadia, Yaniv Linde, C. Haskell-Luevano, M. Dirain +4 more
2010Bioorganic & Medicinal Chemistry43 citations Open access
Semantic Scholar
Old Mice Demonstrate Organ Dysfunction as well as Prolonged Inflammation, Immunosuppression, and Weight Loss in a Modified Surgical Sepsis Model
Julie A. Stortz, Mckenzie Hollen, D. Nacionales, Hiroyuki Horiguchi +18 more
2019Critical Care Medicine41 citations Open access
Semantic Scholar
Active muscle regeneration following eccentric contraction-induced injury is similar between healthy young and older adults.
T. Buford, R. G. Macneil, Launa G. Clough, M. Dirain +4 more
2014Journal of applied physiology37 citations Open access
Semantic Scholar
Overlapping but Disparate Inflammatory and Immunosuppressive Responses to SARS-CoV-2 and Bacterial Sepsis: An Immunological Time Course Analysis
Tyler J. Loftus, R. Ungaro, M. Dirain, P. Efron +8 more
2021Frontiers in Immunology36 citations Open access
Semantic Scholar
Intraoperative hemidiaphragm electrical stimulation reduces oxidative stress and upregulates autophagy in surgery patients undergoing mechanical ventilation: exploratory study
R. Mankowski, Shakeel Ahmed, T. Beaver, M. Dirain +7 more
2016Journal of Translational Medicine35 citations Open access
Semantic Scholar
1,4-Disubstituted-[1,2,3]triazolyl-Containing Analogues of MT-II: Design, Synthesis, Conformational Analysis, and Biological Activity
Chiara Testa, M. Scrima, M. Grimaldi, A. D'Ursi +7 more
2014Journal of Medicinal Chemistry34 citations Open access
Semantic Scholar
Identification of Tetrapeptides from a Mixture Based Positional Scanning Library That Can Restore nM Full Agonist Function of the L106P, I69T, I102S, A219V, C271Y, and C271R Human Melanocortin-4 Polymorphic Receptors (hMC4Rs)
Erica M. Haslach, Hui-Suo Huang, M. Dirain, Ginamarie Debevec +9 more
2014Journal of Medicinal Chemistry22 citations Open access
Semantic Scholar
Evaluation of a Multivalent Transcriptomic Metric for Diagnosing Surgical Sepsis and Estimating Mortality Among Critically Ill Patients
Scott C. Brakenridge, Uan-I Chen, Tyler J. Loftus, R. Ungaro +14 more
2022JAMA Network Open21 citations Open access
Semantic Scholar
SEX DIFFERENCES ASSOCIATE WITH LATE MICROBIOME ALTERATIONS AFTER MURINE SURGICAL SEPSIS
P. Efron, D. Darden, Eric C. Li, J. Munley +16 more
2022Journal of Trauma and Acute Care Surgery21 citations Open access
Semantic Scholar
Septic Stability? Gut Microbiota in Young Adult Mice Maintains Overall Stability after Sepsis Compared to Old Adult Mice
R. Mankowski, Ryan M. Thomas, D. Darden, R. Gharaibeh +14 more
2020Shock21 citations Open access
Semantic Scholar
Effects of blood flow restriction on biomarkers of myogenesis in response to resistance exercise
Andrew S. Layne, Kelly Larkin-Kaiser, R. MacNeil, M. Dirain +3 more
2016Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme17 citations Open access
Semantic Scholar
Incorporation of a Bio-Active Reverse-Turn Heterocycle into a Peptide Template Using Solid-Phase Synthesis to Probe Melanocortin Receptor Selectivity and Ligand Conformations by 2D 1H NMR
Anamika Singh, Andrzej M. Wilczynski, J. R. Holder, Rachel M. Witek +4 more
2011Journal of Medicinal Chemistry16 citations Open access
Semantic Scholar
Sepsis is associated with reduced spontaneous neutrophil migration velocity in human adults
Steven L. Raymond, Russell B. Hawkins, Julie A. Stortz, Tyler J Murphy +11 more
2018PLoS ONE15 citations Open access
Semantic Scholar
Discovery of Mixed Pharmacology Melanocortin-3 Agonists and Melanocortin-4 Receptor Tetrapeptide Antagonist Compounds (TACOs) Based on the Sequence Ac-Xaa1-Arg-(pI)DPhe-Xaa4-NH2
Skye R. Doering, K. Freeman, Sathya M. Schnell, Erica M. Haslach +10 more
2017Journal of Medicinal Chemistry15 citations Open access
Semantic Scholar
Synthesis, Biophysical, and Pharmacological Evaluation of the Melanocortin Agonist AST3-88: Modifications of Peptide Backbone at Trp 7 Position Lead to a Potent, Selective, and Stable Ligand of the Melanocortin 4 Receptor (MC4R)
Anamika Singh, M. Dirain, Andrzej M. Wilczynski, Chi Chen +4 more
2014ACS Chemical Neuroscience11 citations Open access
Semantic Scholar
Structure-Activity Relationships of Peptides Incorporating a Bioactive Reverse-Turn Heterocycle at the Melanocortin Receptors: Identification of a 5,800-fold Mouse Melanocortin-3 Receptor (mMC3R) Selective Antagonist/Partial Agonist versus the Mouse Melanocortin-4 Receptor (mMC4R)
Anamika Singh, M. Dirain, Rachel M. Witek, J. Rocca +2 more
2013Journal of Medicinal Chemistry11 citations Open access
Semantic Scholar
Corrigendum to “Calorie restriction combined with resveratrol induces autophagy and protects 26-month-old rat hearts from doxorubicin-induced toxicity” [Free Radic. Biol. Med. 74 (2014) 252–262]
Debapriya Dutta, Jin-Ze Xu, M. Dirain, C. Leeuwenburgh
20159 citations
Semantic Scholar
Effect of oral administration of bismuth compounds on Campylobacter colonization in broilers.
M. Farnell, A. Donoghue, F. Solís de los Santos, I. Reyes-Herrera +5 more
2006Poultry Science8 citations Open access
Semantic Scholar
Human β-Defensin-1 and β-Defensin-3 (Mouse Ortholog mBD14) Function as Full Endogenous Agonists at Select Melanocortin Receptors
Mark D. Ericson, Anamika Singh, S. R. Tala, Erica M. Haslach +11 more
2018Journal of Medicinal Chemistry7 citations Open access
Semantic Scholar
Litter Treatment with Aluminum Sulfate (Alum) Produced an Inconsistent Reduction in Horizontal Transmission of Campylobacter in Chickens
K. Arsi, Philip A. Moore, A. Donoghue, M. Dirain +1 more
20174 citations Open access
Semantic Scholar
Synthesis and Structure-Activity Relationships of Substituted Urea Derivatives on Mouse Melanocortin Receptors.
Anamika Singh, J. Kast, M. Dirain, Hui-Suo Huang +1 more
2016ACS Chemical Neuroscience4 citations Open access
Semantic Scholar
Semi-Rigid Tripeptide Agonists of Melanocortin Receptors
Andrew R. Ruwe, L. Koikov, Z. Abdel-Malek, C. Haskell-Luevano +5 more
2009Bioorganic & Medicinal Chemistry Letters3 citations Open access
Semantic Scholar
Effects of Blood Flow Restriction on Biomarkers of Myogenesis Among Healthy Young Adults: 3700 Board #139 June 4, 9: 30 AM - 11: 00 AM.
Andrew S. Layne, Kelly Larkin-Kaiser, Gavin MacNeil, M. Dirain +3 more
2016Medicine & Science in Sports & Exercise1 citations
Semantic Scholar
Phospholipase D 2 ( PLD 2 ) is crucial for oxidized cholesterol uptake and foam cell formation in atherosclerotic plaques
Osric A. Forrest, Milton R. Brown, J. Alvarez, R. Tirouvanziam +15 more
20170 citations
Semantic Scholar
Design, Synthesis, Conformational Analysis, and Biological Activity
Chiara Testa, M. Scrima, M. Grimaldi, M. Dirain +6 more
20140 citations
Semantic Scholar
is similar between healthy young and older adults
T. Buford, R. MacNeil, Launa G. Clough, M. Dirain +3 more
20130 citations
Semantic Scholar
Forages and Pastures - Livestock and Poultry: Understanding Diet Selection in Temperate Biodiverse Pasture Systems
I. Reyes-Herrera, V. Aguiar, M. Dirain, F. Solís de los Santos +3 more
20070 citations
Semantic Scholar
The effect of Campylobacter colonization on the gastrointestinal tract in broilers
M. Dirain
20070 citations
Semantic Scholar
Lipoic acid-induced changes in food intake in chickens
D. Denbow, P. Siegel, B. Leclerc, S. Kang +17 more
20070 citations
Semantic Scholar

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