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K. Nierhaus · SciRah

Researcher profile · Semantic Scholar

K. Nierhaus

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K. Nierhaus — researcher profile on SciRah

h-index: 72
Works: 369
Citations: 16K

Most-cited papers

Small RNA binding to 5' mRNA coding region inhibits translational initiation.
Marie Bouvier, C. Sharma, Franziska Mika, K. Nierhaus +1 more
2008Molecules and Cells278 citations Open access
Semantic Scholar
The highly conserved LepA is a ribosomal elongation factor that back-translocates the ribosome.
Yan Qin, Norbert Polacek, O. Vesper, Eike Staub +3 more
2006Cell226 citations Open access
Semantic Scholar
The Weird and Wonderful World of Bacterial Ribosome Regulation
D. Wilson, K. Nierhaus
2007Critical reviews in biochemistry and molecular biology223 citations
Semantic Scholar
Ribosomal Proteins in the Spotlight
D. Wilson, K. Nierhaus
2005Critical reviews in biochemistry and molecular biology202 citations
Semantic Scholar
Dissecting the ribosomal inhibition mechanisms of edeine and pactamycin: the universally conserved residues G693 and C795 regulate P-site RNA binding.
G. Dinos, D. Wilson, Y. Teraoka, Witold Szaflarski +3 more
2004Molecules and Cells155 citations Open access
Semantic Scholar
Regulation of the mammalian elongation cycle by subunit rolling: a eukaryotic-specific ribosome rearrangement
T. Budkevich, Jan Giesebrecht, E. Behrmann, J. Loerke +8 more
2014Cell149 citations Open access
Semantic Scholar
The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation
F. Schluenzen, C. Takemoto, D. Wilson, T. Kaminishi +8 more
2006Nature Structural &Molecular Biology137 citations Open access
Semantic Scholar
Heptameric (L12)6/L10 rather than canonical pentameric complexes are found by tandem MS of intact ribosomes from thermophilic bacteria.
Leopold L. Ilag, H. Videler, A. R. McKay, F. Sobott +3 more
2005Proceedings of the National Academy of Sciences of the United States of America132 citations Open access
Semantic Scholar
An unexpected type of ribosomes induced by kasugamycin: A look into ancestral times of protein synthesis?
A. Kaberdina, Witold Szaflarski, K. Nierhaus, I. Moll
2009Molecules and Cells116 citations Open access
Semantic Scholar
Three-dimensional structures of translating ribosomes by Cryo-EM.
R. Gilbert, P. Fucini, S. Connell, S. Fuller +4 more
2004Molecules and Cells113 citations Open access
Semantic Scholar
RsfA (YbeB) Proteins Are Conserved Ribosomal Silencing Factors
R. Häuser, Markus Pech, Jaroslaw Kijek, Hiroshi Yamamoto +10 more
2012PLoS Genetics107 citations Open access
Semantic Scholar
Structure and dynamics of the mammalian ribosomal pre-translocation complex
T. Budkevich, Jan Giesebrecht, R. Altman, James B Munro +4 more
2011Molecules and Cells104 citations Open access
Semantic Scholar
Mg2+, K+, and the Ribosome
K. Nierhaus
2014Journal of Bacteriology100 citations Open access
Semantic Scholar
70S-scanning initiation is a novel and frequent initiation mode of ribosomal translation in bacteria
Hiroshi Yamamoto, D. Wittek, Romi Gupta, B. Qin +6 more
2016Proceedings of the National Academy of Sciences of the United States of America94 citations Open access
Semantic Scholar
Heteronuclear NMR investigations of dynamic regions of intact Escherichia coli ribosomes.
J. Christodoulou, Göran Larsson, P. Fucini, S. Connell +7 more
2004Proceedings of the National Academy of Sciences of the United States of America91 citations Open access
Semantic Scholar
Cell-free protein expression and functional assay in nanowell chip format.
P. Angenendt, L. Nyársik, Witold Szaflarski, J. Glökler +4 more
2004Analytical Chemistry91 citations
Semantic Scholar
Elongation factor 4 (EF4/LepA) accelerates protein synthesis at increased Mg2+ concentrations
Markus Pech, Zhala Karim, Hiroshi Yamamoto, M. Kitakawa +2 more
2011Proceedings of the National Academy of Sciences of the United States of America88 citations Open access
Semantic Scholar
Species-specific antibiotic-ribosome interactions: implications for drug development
D. Wilson, J. Harms, K. Nierhaus, F. Schlünzen +1 more
2005Biological chemistry88 citations
Semantic Scholar
The complex of tmRNA–SmpB and EF-G on translocating ribosomes
D.J.F. Ramrath, Hiroshi Yamamoto, Kristian Rother, D. Wittek +9 more
2012Nature84 citations
Semantic Scholar
EF-G-dependent GTPase on the ribosome. conformational change and fusidic acid inhibition.
H. Seo, S. Abedin, Detlev Kamp, D. Wilson +2 more
2006Biochemistry82 citations
Semantic Scholar
NOA1 is an essential GTPase required for mitochondrial protein synthesis
M. Kolanczyk, Markus Pech, T. Żemojtel, Hiroshi Yamamoto +19 more
2011Molecular Biology of the Cell80 citations Open access
Semantic Scholar
Translation and folding of single proteins in real time
Florian Wruck, Alexandros Katranidis, K. Nierhaus, G. Büldt +1 more
2017Proceedings of the National Academy of Sciences of the United States of America79 citations Open access
Semantic Scholar
A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation
S. Connell, M. Topf, Yan Qin, D. Wilson +4 more
2008Nature Structural &Molecular Biology74 citations
Semantic Scholar
EF-G2mt is an exclusive recycling factor in mammalian mitochondrial protein synthesis.
Masafumi Tsuboi, Hiroyuki Morita, Y. Nozaki, Kenta Akama +4 more
2009Molecules and Cells73 citations Open access
Semantic Scholar
Ribosome reactivation by replacement of damaged proteins
Arto Pulk, Aivar Liiv, L. Peil, Ü. Maiväli +2 more
2010Molecular Microbiology71 citations
Semantic Scholar
Ribosome Rescue and Translation Termination at Non-Standard Stop Codons by ICT1 in Mammalian Mitochondria
Shiori Akabane, T. Ueda, K. Nierhaus, N. Takeuchi
2014PLoS Genetics69 citations Open access
Semantic Scholar
The E-site story: the importance of maintaining two tRNAs on the ribosome during protein synthesis
D. N. Wilson, K. Nierhaus
2006Cellular and Molecular Life Sciences (CMLS)69 citations Open access
Semantic Scholar
EF-G and EF4: translocation and back-translocation on the bacterial ribosome
Hiroshi Yamamoto, Yan Qin, J. Achenbach, Chengmin Li +3 more
2013Nature Reviews Microbiology67 citations
Semantic Scholar
Troubleshooting coupled in vitro transcription–translation system derived from Escherichia coli cells: synthesis of high-yield fully active proteins
M. Iskakova, Witold Szaflarski, M. Dreyfus, J. Remme +1 more
2006Nucleic Acids Research67 citations Open access
Semantic Scholar
Structural basis for the binding of IRES RNAs to the head of the ribosomal 40S subunit
Margarita Muhs, Hiroshi Yamamoto, J. Ismer, H. Takaku +7 more
2011Nucleic Acids Research61 citations Open access
Semantic Scholar
Outwitting EF-Tu and the ribosome: translation with d-amino acids
J. Achenbach, M. Jahnz, L. Bethge, K. Paal +6 more
2015Nucleic Acids Research60 citations Open access
Semantic Scholar
Ribosomal Proteins: Role in Ribosomal Functions
D. Wilson, Romi Gupta, A. Mikolajka, K. Nierhaus
200957 citations
Semantic Scholar
New features of the ribosome and ribosomal inhibitors: non-enzymatic recycling, misreading and back-translocation.
Witold Szaflarski, O. Vesper, Y. Teraoka, Beata Plitta +2 more
2008Journal of Molecular Biology57 citations
Semantic Scholar
Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
R. Nikolay, T. Hilal, B. Qin, T. Mielke +5 more
2018Molecules and Cells53 citations Open access
Semantic Scholar
Protein synthesis and ribosome structure : translating the genome
K. Nierhaus, D. Wilson
200453 citations
Semantic Scholar
Fast biosynthesis of GFP molecules: a single-molecule fluorescence study.
Alexandros Katranidis, D. Atta, R. Schlesinger, K. Nierhaus +5 more
2009Angewandte Chemie52 citations
Semantic Scholar
Decoding errors and the involvement of the E-site.
K. Nierhaus
2006Biochimie49 citations
Semantic Scholar
Deacylated tRNA is released from the E site upon A site occupation but before GTP is hydrolyzed by EF-Tu
G. Dinos, D. Kalpaxis, D. Wilson, K. Nierhaus
2005Nucleic Acids Research49 citations Open access
Semantic Scholar
Features of 80S mammalian ribosome and its subunits
T. Budkevich, A. El'skaya, K. Nierhaus
2008Nucleic Acids Research43 citations Open access
Semantic Scholar
EF-G catalyzes tRNA translocation by disrupting interactions between decoding center and codon–anticodon duplex
Guangqiao Liu, G. Song, Dan-Yang Zhang, De-Jiu Zhang +8 more
2014Nature Structural &Molecular Biology41 citations
Semantic Scholar
Stepping Transfer Messenger RNA through the Ribosome*
O. Shpanchenko, Maria I Zvereva, P. Ivanov, E. Y. Bugaeva +6 more
2005Journal of Biological Chemistry33 citations Open access
Semantic Scholar
Reconstitution of 30S ribosomal subunits in vitro using ribosome biogenesis factors
Daichi Tamaru, Kazuaki Amikura, Y. Shimizu, K. Nierhaus +1 more
2018RNA: A publication of the RNA Society28 citations Open access
Semantic Scholar
The inhibition pattern of antibiotics on the extent and accuracy of tRNA binding to the ribosome, and their effect on the subsequent steps in chain elongation.
P. Wurmbach, K. Nierhaus
2005European Journal of Biochemistry28 citations
Semantic Scholar
Shine–Dalgarno interaction prevents incorporation of noncognate amino acids at the codon following the AUG
Viviana Di Giacco, V. Márquez, Yan Qin, Markus Pech +3 more
2008Proceedings of the National Academy of Sciences of the United States of America27 citations Open access
Semantic Scholar
Lys53 of Ribosomal Protein L36AL and the CCA End of a tRNA at the P/E Hybrid Site Are in Close Proximity on the Human Ribosome
C. Hountondji, K. Bulygin, A. Woisard, P. Tufféry +5 more
2012ChemBioChem26 citations
Semantic Scholar
Question 7: Optimized Energy Consumption for Protein Synthesis
Witold Szaflarski, K. Nierhaus
2007Origins of Life and Evolution of Biospheres25 citations
Semantic Scholar
Ribosome Assembly as Antimicrobial Target
R. Nikolay, S. Schmidt, Renate Schlömer, E. Deuerling +1 more
2016Antibiotics22 citations Open access
Semantic Scholar
A conserved proline switch on the ribosome facilitates the recruitment and binding of trGTPases
Li Wang, Fang Yang, De-Jiu Zhang, Zhi Chen +4 more
2012Nature Structural &Molecular Biology22 citations
Semantic Scholar
Mapping of the second tetracycline binding site on the ribosomal small subunit of E.coli.
M. Anokhina, A. Barta, K. Nierhaus, V. Spiridonova +1 more
2004Nucleic Acids Research22 citations Open access
Semantic Scholar
The CCA-end of P-tRNA Contacts Both the Human RPL36AL and the A-site Bound Translation Termination Factor eRF1 at the Peptidyl Transferase Center of the Human 80S Ribosome
C. Hountondji, K. Bulygin, J. Créchet, A. Woisard +6 more
2014Open Biochemistry Journal19 citations Open access
Semantic Scholar

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