Researcher profile · Semantic Scholar

J. Cleynhens

h-index: 11
Works: 33
Citations: 355

Most-cited papers

Dopamine transporter SPECT using fast kinetic ligands: 123I-FP-β-CIT versus 99mTc-TRODAT-1
K. van Laere, L. de Ceuninck, R. Dom, J. Van den Eynden +6 more
2004European Journal of Nuclear Medicine and Molecular Imaging63 citations
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Synthesis of 18F-labelled 2-(4'-fluorophenyl)-1,3-benzothiazole and evaluation as amyloid imaging agent in comparison with [11C]PIB.
K. Serdons, T. Verduyckt, D. Vanderghinste, J. Cleynhens +8 more
2009Bioorganic & Medicinal Chemistry Letters51 citations Open access
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Synthesis and evaluation of a 99mTc-BAT-phenylbenzothiazole conjugate as a potential in vivo tracer for visualization of amyloid β
K. Serdons, T. Verduyckt, J. Cleynhens, C. Terwinghe +3 more
200744 citations
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11C-labelled PIB analogues as potential tracer agents for in vivo imaging of amyloid beta in Alzheimer's disease.
K. Serdons, T. Verduyckt, D. Vanderghinste, P. Borghgraef +5 more
2009European journal of medicinal chemistry34 citations Open access
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Radioiodinated Phenylalkyl Malonic Acid Derivatives as pH-Sensitive SPECT Tracers
M. Bauwens, M. De Saint-Hubert, J. Cleynhens, Laura Brams +3 more
2012PLoS ONE20 citations Open access
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Evaluation of PET radioligands for in vivo visualization of phosphodiesterase 5 (PDE5).
Rufael Chekol, O. Gheysens, J. Cleynhens, P. Pokreisz +5 more
2014Nuclear Medicine and Biology17 citations
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Development of 99mTc‐thioflavin‐T derivatives for detection of systemic amyloidosis
K. Serdons, T. Verduyckt, J. Cleynhens, G. Bormans +1 more
200815 citations
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In vitro and in vivo comparison of 18F and 123I-labeled ML10 with 68Ga-Cys2-AnxA5 for molecular imaging of apoptosis.
M. Bauwens, M. De Saint-Hubert, J. Cleynhens, C. Vandeputte +2 more
2013The Quarterly Journal of Nuclear Medicine and Molecular Imaging12 citations
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New transient receptor potential vanilloid subfamily member 1 positron emission tomography radioligands: synthesis, radiolabeling, and preclinical evaluation.
D. van Veghel, J. Cleynhens, L. Pearce, Ian A. DeAndrea-Lazarus +4 more
2013ACS Chemical Neuroscience12 citations Open access
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Synthesis and biological evaluation of [11C]SB366791: A new PET-radioligand for in vivo imaging of the TRPV1 receptor
D. van Veghel, J. Cleynhens, L. Pearce, P. Blumberg +3 more
2012Nuclear Medicine and Biology11 citations Open access
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Synthesis and biological evaluation of (11)C-labeled beta-galactosyl triazoles as potential PET tracers for in vivo LacZ reporter gene imaging.
Sofie Celen, J. Cleynhens, C. Deroose, T. de Groot +6 more
2009Bioorganic & Medicinal Chemistry11 citations Open access
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Synthesis and evaluation of two uncharged 99mTc‐labeled derivatives of thioflavin‐T as potential tracer agents for fibrillar brain amyloid
K. Serdons, D. Vanderghinste, M. Van Eeckhoudt, J. Cleynhens +3 more
200911 citations
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Radiolabeling and preliminary biological evaluation of a (99m)Tc(CO)(3) labeled 3,3'-(benzylidene)-bis-(1H-indole-2-carbohydrazide) derivative as a potential SPECT tracer for in vivo visualization of necrosis.
K. Prinsen, Lixin Jin, K. Vunckx, M. De Saint-Hubert +6 more
2011Bioorganic & Medicinal Chemistry Letters9 citations
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Impurity profiling of N,N'-ethylenebis-l-cysteine diethyl ester (Bicisate).
O. Wahl, J. Cleynhens, A. Verbruggen, U. Holzgrabe
2018Journal of Pharmaceutical and Biomedical Analysis8 citations
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Carbon-11 and Fluorine-18 Radiolabeled Pyridopyrazinone Derivatives for Positron Emission Tomography (PET) Imaging of Phosphodiesterase-5 (PDE5).
Rufael Chekol, O. Gheysens, M. Ahamed, J. Cleynhens +5 more
2017Journal of Medicinal Chemistry8 citations
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Synthesis and biological evaluation of 68Ga labeled bis-DOTA-3,3'-(benzylidene)-bis-(1H-indole-2-carbohydrazide) as a PET tracer for in vivo visualization of necrosis.
K. Prinsen, M. Cona, J. Cleynhens, H. Vanbilloen +6 more
2013Bioorganic & Medicinal Chemistry Letters8 citations
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Structure–biodistribution relation of neutral 99mTc(CO)3-complexes with tridentate N-substituted derivatives of aminoethylglycine and phenylenediamine
Dirk Rattat, J. Cleynhens, C. Terwinghe, An-Elisabeth De Greve +1 more
20066 citations Open access
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99mTc-tricarbonyl labeled agents for cell labeling: development, biodistribution in normal mice and preliminary in vitro evaluation.
H. Fonge, Lixin Jin, J. Cleynhens, G. Bormans +1 more
2010Bioorganic & Medicinal Chemistry5 citations
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Synthesis and evaluation of a (99m)Tc-BAT-phenylbenzothiazole conjugate as a potential in vivo tracer for visualization of amyloid beta.
K. Serdons, T. Verduyckt, J. Cleynhens, C. Terwinghe +3 more
2007Bioorganic & Medicinal Chemistry Letters5 citations
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Technetium-99m radiopharmaceuticals—Radiochemistry and radiolabeling
J. Cleynhens, A. Verbruggen
2021Reference Module in Biomedical Sciences3 citations
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Labelling and preliminary biological evaluation of [C-11]RBQ08 as a specific PDE5 radiotracer
Rufael Chekol, O. Gheysens, J. Cleynhens, S. Janssens +2 more
20111 citations
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Oral Presentations_Tuesday
M. De Angelis, S. Chitneni, J. Alcázar, M. Koole +27 more
2009European Journal of Nuclear Medicine and Molecular Imaging1 citations Open access
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High yield synthesis and metabolite analysis of the dopamine transporter (DAT) ligand [18F]FECT
S. Chitneni, N. Evens, Peter Vermaelen, Marva Bex +7 more
20071 citations
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[C-11]JC4714 as a potential radioligand for in vivo visualization of phosphodiesterase 5
Rufael Chekol, O. Gheysens, J. Cleynhens, S. Janssens +2 more
20130 citations
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[11C]RPP07B: A potential radioligand for in vivo visualization of PDE5 in myocardium and brain
Rufael Chekol, O. Gheysens, J. Cleynhens, S. Janssens +2 more
20130 citations
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Fluorine-18 and carbon-11 labeled vardenafil derivatives for in vivo visualization of phosphodiesterase 5 in myocardium
Rufael Chekol, O. Gheysens, J. Cleynhens, S. Janssens +2 more
20120 citations
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In vitro and in vivo evaluation of novel PET probes as potential red blood cell imaging agents
Vamsidhar Akurathi, O. Gheysens, T. Dresselaers, M. Koole +7 more
20110 citations
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Radiosynthesis and preliminary evaluation of [68Ga]-bis-DOTA-PA for early non-invasive PET imaging of necrosis
K. Prinsen, M. Cona, J. Cleynhens, Jun-Jie Li +5 more
20100 citations
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Synthesis and preliminary evaluation of a PET probe targeting carbonic anhydrase IX (CA IX) for in vivo visualisation of tumor hypoxia
Vamsidhar Akurathi, L. Dubois, N. Lieuwes, J. Cleynhens +3 more
20100 citations
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Synthesis and Biological evaluation of C11-Labeled B-Galactosyl trizoles as potential pet tracers for in vivo imaging of lacz reporter gene expression
Sofie Celen, J. Cleynhens, C. Deroose, T. de Groot +2 more
20090 citations
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Synthesis, labbelling and radio-LC-MS analysis of 99m Tc-techmazenil
Davy M. J. Kieffer, J. Cleynhens, K. Verbeke, A. Verbruggen +1 more
20020 citations
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Optimalisation of analytical methods for identification and quality control of 99m Tc-sestamibi for a Ph. Eur. Monograph
M. Kosiński, C. Terwinghe, J. Cleynhens, H. Vanbilloen +4 more
20020 citations
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Synthesis and biological evaluation of 99m Tc-BAT-N-propyl propionate
Davy M. J. Kieffer, J. Cleynhens, K. Verbeke, A. Verbruggen +1 more
20020 citations
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