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S. Chitneni · SciRah

Researcher profile · Semantic Scholar

S. Chitneni

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S. Chitneni — researcher profile on SciRah

h-index: 17
Works: 50
Citations: 1,316

Most-cited papers

Molecular Imaging of Hypoxia
S. Chitneni, G. Palmer, M. Zalutsky, M. Dewhirst
2011Journal of Nuclear Medicine303 citations Open access
Semantic Scholar
Copper Signaling Axis as a Target for Prostate Cancer Therapeutics
Rachid Safi, Erik R. Nelson, S. Chitneni, K. Franz +3 more
2014Cancer Research182 citations Open access
Semantic Scholar
Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis Progression
Kuo Du, S. Chitneni, A. Suzuki, Ying Wang +8 more
2019Cellular and Molecular Gastroenterology and Hepatology104 citations Open access
Semantic Scholar
Synthesis and biological evaluation of a 99mTc-labelled sulfonamide conjugate for in vivo visualization of carbonic anhydrase IX expression in tumor hypoxia.
Vamsidhar Akurathi, L. Dubois, N. Lieuwes, S. Chitneni +6 more
2010Nuclear Medicine and Biology88 citations Open access
Semantic Scholar
Radiolabeled inhibitors as probes for imaging mutant IDH1 expression in gliomas: synthesis and preliminary evaluation of labeled butyl-phenyl sulfonamide analogs
S. Chitneni, Z. Reitman, David M. Gooden, Hai Yan +1 more
2016European journal of medicinal chemistry85 citations Open access
Semantic Scholar
Preclinical Evaluation of 18F-JNJ41510417 as a Radioligand for PET Imaging of Phosphodiesterase-10A in the Brain
Sofie Celen, M. Koole, M. De Angelis, Ivan Sannen +10 more
2010Journal of Nuclear Medicine60 citations Open access
Semantic Scholar
A Rationally Designed Fully Human EGFRvIII:CD3-Targeted Bispecific Antibody Redirects Human T Cells to Treat Patient-derived Intracerebral Malignant Glioma
P. Gedeon, Teilo H. Schaller, S. Chitneni, Bryan D. Choi +15 more
2018Clinical Cancer Research49 citations Open access
Semantic Scholar
Development and biological evaluation of ⁹⁹mTc-sulfonamide derivatives for in vivo visualization of CA IX as surrogate tumor hypoxia markers.
Vamsidhar Akurathi, L. Dubois, Sofie Celen, N. Lieuwes +7 more
2014European journal of medicinal chemistry49 citations Open access
Semantic Scholar
Synthesis and evaluation of 18F- and 11C-labeled phenyl-galactopyranosides as potential probes for in vivo visualization of LacZ gene expression using positron emission tomography.
Sofie Celen, C. Deroose, T. de Groot, S. Chitneni +5 more
2008Bioconjugate chemistry47 citations
Semantic Scholar
18F-EF5 PET Imaging as an Early Response Biomarker for the Hypoxia-Activated Prodrug SN30000 Combined with Radiation Treatment in a Non–Small Cell Lung Cancer Xenograft Model
S. Chitneni, G. Bida, Hong Yuan, G. Palmer +5 more
2013Journal of Nuclear Medicine38 citations Open access
Semantic Scholar
Fluorine-18 labeling of an anti-HER2 VHH using a residualizing prosthetic group via a strain-promoted click reaction: chemistry and preliminary evaluation
Zheng-Yuan Zhou, S. Chitneni, N. Devoogdt, M. Zalutsky +1 more
2018Bioorganic & Medicinal Chemistry32 citations Open access
Semantic Scholar
Efficient purification and metabolite analysis of radiotracers using high-performance liquid chromatography and on-line solid-phase extraction.
S. Chitneni, K. Serdons, N. Evens, H. Fonge +6 more
2008Journal of Chromatography A28 citations
Semantic Scholar
Synthesis and evaluation of radiolabeled AGI-5198 analogues as candidate radiotracers for imaging mutant IDH1 expression in tumors
S. Chitneni, Z. Reitman, Rebecca Spicehandler, David M. Gooden +2 more
2018Bioorganic & Medicinal Chemistry Letters25 citations Open access
Semantic Scholar
Necrosis avidity of (99m)Tc(CO)3-labeled pamoic acid derivatives: synthesis and preliminary biological evaluation in animal models of necrosis.
H. Fonge, S. Chitneni, Lixin Jin, K. Vunckx +6 more
2007Bioconjugate chemistry25 citations
Semantic Scholar
Comparison of the Hypoxia PET Tracer 18F-EF5 to Immunohistochemical Marker EF5 in 3 Different Human Tumor Xenograft Models
S. Chitneni, G. Bida, M. Zalutsky, M. Dewhirst
2014Journal of Nuclear Medicine22 citations Open access
Semantic Scholar
Fetal gene transfer with lentiviral vectors: long-term in vivo follow-up evaluation in a rat model.
J. Toelen, C. Deroose, R. Gijsbers, Veerle Reumers +7 more
2007American Journal of Obstetrics and Gynecology19 citations
Semantic Scholar
Synthesis and Evaluation of a 18F-Labeled Triazinediamine Analogue for Imaging Mutant IDH1 Expression in Gliomas by PET.
S. Chitneni, Hai Yan, M. Zalutsky
2018ACS Medicinal Chemistry Letters18 citations Open access
Semantic Scholar
A simplified synthesis of the hypoxia imaging agent 2-(2-Nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-[18F]pentafluoropropyl)-acetamide ([18F]EF5)
S. Chitneni, G. Bida, M. Dewhirst, M. Zalutsky
2011Nuclear Medicine and Biology15 citations Open access
Semantic Scholar
Accelerator-Based Production of Scandium Radioisotopes for Applications in Prostate Cancer: Toward Building a Pipeline for Rapid Development of Novel Theranostics
Jason P. Meier, Hannah J. Zhang, R. Freifelder, Mohammed P. I. Bhuiyan +20 more
2023Molecules14 citations Open access
Semantic Scholar
Improved synthesis and metabolic stability analysis of the dopamine transporter ligand [(18)F]FECT.
S. Chitneni, L. Garreau, B. Cleynhens, N. Evens +8 more
2008Nuclear Medicine and Biology14 citations
Semantic Scholar
D-amino acid peptide residualizing agents bearing N-hydroxysuccinimido-and maleimido- functional groups and their application for trastuzumab radioiodination
M. Pruszyński, E. Koumarianou, G. Vaidyanathan, S. Chitneni +1 more
2014Nuclear Medicine and Biology12 citations Open access
Semantic Scholar
Preliminary validation of varicella zoster virus thymidine kinase as a novel reporter gene for PET.
C. Deroose, S. Chitneni, R. Gijsbers, Peter Vermaelen +8 more
2012Nuclear Medicine and Biology12 citations
Semantic Scholar
Synthesis and preliminary evaluation of 18F- or 11C-labeled bicyclic nucleoside analogues as potential probes for imaging varicella-zoster virus thymidine kinase gene expression using positron emission tomography.
S. Chitneni, C. Deroose, J. Balzarini, R. Gijsbers +6 more
2007Journal of Medicinal Chemistry12 citations Open access
Semantic Scholar
Observations on the Effects of Residualization and Dehalogenation on the Utility of N-Succinimidyl Ester Acylation Agents for Radioiodination of the Internalizing Antibody Trastuzumab
S. Chitneni, E. Koumarianou, G. Vaidyanathan, M. Zalutsky
2019Molecules11 citations Open access
Semantic Scholar
A p-[18F]fluoroethoxyphenyl bicyclic nucleoside analogue as a potential positron emission tomography imaging agent for varicella-zoster virus thymidine kinase gene expression.
S. Chitneni, C. Deroose, J. Balzarini, R. Gijsbers +5 more
2007Journal of Medicinal Chemistry9 citations Open access
Semantic Scholar
Stapled peptides as scaffolds for developing radiotracers for intracellular targets: preliminary evaluation of a radioiodinated MDM2-binding stapled peptide in the SJSA-1 osteosarcoma model
Zheng-Yuan Zhou, M. Zalutsky, S. Chitneni
2022Bioorganic & Medicinal Chemistry Letters7 citations Open access
Semantic Scholar
A concise review on MDM2 inhibitors and recent progress in radiopharmaceutical development for imaging MDM2 expression in tumors with PET or SPECT.
Atchimnaidu Siriki, Graham Ragland, Janardhan Vasireddy, S. Chitneni
2025Bioorganic & Medicinal Chemistry Letters6 citations
Semantic Scholar
Fluorine-18 Labeling of the MDM2 Inhibitor RG7388 for PET Imaging: Chemistry and Preliminary Evaluation
Zheng-Yuan Zhou, M. Zalutsky, S. Chitneni
2021Molecular Pharmaceutics5 citations Open access
Semantic Scholar
Synthesis and biological evaluation of an 123I-labeled bicyclic nucleoside analogue (BCNA) as potential SPECT tracer for VZV-tk reporter gene imaging.
S. Chitneni, C. Deroose, H. Fonge, R. Gijsbers +6 more
2007Bioorganic & Medicinal Chemistry Letters5 citations Open access
Semantic Scholar
Feasibility of Developing Radiotracers for MDM2: Synthesis and Preliminary Evaluation of an 18F-Labeled Analogue of the MDM2 Inhibitor SP-141
S. Chitneni, Zheng-Yuan Zhou, Brian Watts, M. Zalutsky
2021Pharmaceuticals4 citations Open access
Semantic Scholar
IDH1 Mutations in Glioma: Considerations for Radiotracer Development
S. Chitneni
2016SM radiology journal3 citations
Semantic Scholar
Pharmacokinetic and Pharmacodynamic Modifiers of EF5 Uptake and Binding
S. Chitneni, G. Bida, Michael R. Zalutsky, M. Dewhirst
2015Journal of Nuclear Medicine3 citations Open access
Semantic Scholar
Synthesis and preliminary biological evaluation of [F-18]JNJ41510417as a radioligand for positron emission tomography imaging of phosphodiesterase-10A in the brain
Sofie Celen, M. De Angelis, S. Chitneni, J. Alcázar +9 more
20092 citations
Semantic Scholar
Imaging of lentiviral vector-mediated gene transfer to mouse muscle with micro positron emission tomography (PET) and bioluminescence imaging (BLI)
C. Deroose, S. Chitneni, R. Gijsbers, Veerle Reumers +5 more
20062 citations
Semantic Scholar
Abstract 5306: 18F-EF5 microPET imaging of treatment response from a novel, hypoxia-selective cytotoxin SN30000 in a human lung cancer xenograft model
S. Chitneni, G. Bida, M. Hay, M. Zalutsky +3 more
20111 citations
Semantic Scholar
[18F]JNJ41510417 a potential PET radioligand for imaging phosphodiesterase-10A in the brain
Sofie Celen, M. Koole, M. De Angelis, Ivan Sannen +10 more
2010NeuroImage1 citations
Semantic Scholar
Oral Presentations_Tuesday
M. De Angelis, S. Chitneni, J. Alcázar, M. Koole +27 more
2009European Journal of Nuclear Medicine and Molecular Imaging1 citations Open access
Semantic Scholar
Synthesis and biological evaluation of carbon-11-labeled acyclic and furo[2,3-d]pyrimidine derivatives of bicyclic nucleoside analogues (BCNAs) for structure–brain uptake relationship study of BCNA tracers
S. Chitneni, J. Balzarini, Sofie Celen, N. Dyubankova +2 more
20081 citations
Semantic Scholar
Synthesis and biological evaluation of a lipophilic, fluorine‐18‐labeled 5‐ethynyl‐2′‐deoxyuridine derivative
S. Chitneni, Tom De Ruymaeker, J. Balzarini, A. Verbruggen +1 more
20071 citations
Semantic Scholar
High yield synthesis and metabolite analysis of the dopamine transporter (DAT) ligand [18F]FECT
S. Chitneni, N. Evens, Peter Vermaelen, Marva Bex +7 more
20071 citations
Semantic Scholar
In vitro evaluation of a novel radiolabeled bi-cyclic nucleoside analog as PET reporter probe for Varicella zoster virus thymidine kinase gene expression
C. Deroose, S. Chitneni, R. Gijsbers, V. Baekelandt +5 more
20071 citations
Semantic Scholar
Application of Waters Oasis column in the purification and metabolite analysis of radiotracers
S. Chitneni, C. Deroose, Z. Debyser, L. Mortelmans +2 more
20071 citations
Semantic Scholar
Synthesis and preliminary evaluation of F-18 and C-11 labelled bi-cyclic nucleoside analogues (BCNAs) as potent PET reporter probes for imaging varicella-zoster virus thymidine kinase (VZV-tk) gene expression
S. Chitneni, C. Deroose, J. Balzarini, A. Verbruggen +1 more
20061 citations
Semantic Scholar
Radiopharmaceutical development for imaging MDM2 overexpression in tumors with PET
S. Chitneni, Zheng-Yuan Zhou, Atchimnaidu Siriki, Graham Ragland
2025Nuclear Medicine and Biology0 citations Open access
Semantic Scholar
Radioiodinated AGI-5198 for in vivo imaging of isocitrate dehydrogenase 1 (IDH1) mutation in gliomas
S. Chitneni, Z. Reitman, Hai Yan, M. Zalutsky
20140 citations
Semantic Scholar
the Hypoxia-Activated Prodrug SN30000 Combined with Radiation Treatment in a Non-Small Cell Lung Cancer Xenograft Model
S. Chitneni, G. Bida, Hong Yuan, G. Palmer +5 more
20130 citations
Semantic Scholar
Synthesis and preliminary biological evaluation of iodine-123labeled bicyclic nucleoside analogue (BCNA) as potential SPECT probe for varicella-zoster virus thymidine kinase (VZV-tk) reporter gene imaging
S. Chitneni, C. Deroose, H. Fonge, R. Gijsbers +5 more
20070 citations
Semantic Scholar
A p-[18F]fluoroethoxyphenyl bi-cyclic nucleoside analog (BCNA) as a promising probe for varicella zoster virus thymidine kinase (VZV-tk) gene expression imaging
S. Chitneni, J. Balzarini, Marva Bex, A. Verbruggen +1 more
20070 citations
Semantic Scholar
In vitro evaluation of varicella-zoster virus (VZV) thymidine kinase as a PET reporter gene with radiolabeled bi-cyclic nucleoside analogs
C. Deroose, S. Chitneni, R. Gijsbers, V. Baekelandt +5 more
20060 citations
Semantic Scholar
Investigation of unknown related substances in erythromycin using liquid chromatography with evaporative light scattering and mass spectrometric detection
S. Chitneni, C. Govaerts, E. Adams, A. Van Schepdael +1 more
20040 citations
Semantic Scholar

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A. Verbruggen×24
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M. Zalutsky×17
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C. Deroose×13
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L. Mortelmans — researcher profile on SciRah

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R. Gijsbers×10

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Sofie Celen — researcher profile on SciRah

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M. Dewhirst — researcher profile on SciRah

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