C. Restaino

Most-cited papers

1. Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors.

   E. Morris, Sharda S. Jha, C. Restaino, P. Dayananth +39 more

   2013Cancer Discovery626 citations

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2. Mast cells are an essential hematopoietic component for polyp development

   E. Gounaris, S. Erdman, C. Restaino, M. Gurish +11 more

   2007Proceedings of the National Academy of Sciences of the United States of America265 citations Open access

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3. Live Imaging of Cysteine-Cathepsin Activity Reveals Dynamics of Focal Inflammation, Angiogenesis, and Polyp Growth

   E. Gounaris, Ching-Hsuan Tung, C. Restaino, René Maehr +6 more

   2008PLoS ONE121 citations Open access

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4. Dissecting Therapeutic Resistance to ERK Inhibition

   Sharda S. Jha, E. Morris, A. Hruza, M. Mansueto +13 more

   2016Molecular Cancer Therapeutics54 citations

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5. Abstract 577: Antagonism of the co-inhibitory receptor BTLA enhances efficacy of anti-PD-1 treatment in murine syngeneic tumor models

   N. Miselis, Douglas E. Linn, C. Restaino, Toya N. Baral +8 more

   20175 citations

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6. Correction: Live Imaging of Cysteine-Cathepsin Activity Reveals Dynamics of Focal Inflammation, Angiogenesis, and Polyp Growth

   E. Gounaris, Ching-Hsuan Tung, C. Restaino, René Maehr +6 more

   2008PLoS ONE5 citations Open access

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7. KDM5 demethylases suppress R-loop-mediated ‘viral mimicry’ and DNA damage in breast cancer cells

   Lena Lau, Kurt W Henderson, Ahu Turkoz, Sara B. Linker +15 more

   2025bioRxiv1 citations Open access

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8. 1367 A highly-selective HPK1 inhibitor enhances T cell receptor signaling and T cell activation potential, increasing antigen recognition and efficacy of PD-1 therapy

   A. Nager, David A. Schaer, Rebecca A. Gallego, Eleanore Hendrickson +13 more

   2022Regular and Young Investigator Award Abstracts1 citations Open access

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9. Abstract 6781: First in class catalytic inhibitor of KAT2A/B demonstrates anti-tumor activity in multiple myeloma

   Kristen Jensen-Pergakes, Shawn M. O’Connell, Sacha Ninkovic, Natalie K. Miller +17 more

   2026Cancer Research0 citations

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10. Dissecting Therapeutic Resistance to ERK Inhibition Rat Wild Type SCH772984 in complex with (3R)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-N-[3-(pyridin-4-yl)-2H-indazol-5-yl]pyrrolidine-3-carboxamide

    Sharda S. Jha, E. Morris, A. Hruza, M. Mansueto +13 more

    20160 citations

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