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G. Knuebel · SciRah

Researcher profile · Semantic Scholar

G. Knuebel

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G. Knuebel — researcher profile on SciRah

h-index: 9
Works: 28
Citations: 173

Most-cited papers

Decitabine demonstrates antileukemic activity in B cell precursor acute lymphoblastic leukemia with MLL rearrangements
C. Roolf, A. Richter, C. Konkolefski, G. Knuebel +7 more
2018Journal of Hematology & Oncology27 citations Open access
Semantic Scholar
Influence of Casein kinase II inhibitor CX-4945 on BCL6-mediated apoptotic signaling in B-ALL in vitro and in vivo
A. Richter, S. Sender, A. Lenz, R. Schwarz +6 more
2020BMC Cancer18 citations Open access
Semantic Scholar
Effective tumor cell abrogation via Venetoclax-mediated BCL-2 inhibition in KMT2A-rearranged acute B-lymphoblastic leukemia
A. Richter, S. Lange, Clemens Holz, Luisa Brock +8 more
2022Cell Death Discovery13 citations Open access
Semantic Scholar
Phosphoproteome Analysis Reveals Differential Mode of Action of Sorafenib in Wildtype and Mutated FLT3 Acute Myeloid Leukemia (AML) Cells
C. Roolf, Nikolaj Dybowski, A. Sekora, S. Mueller +6 more
2017Molecular & Cellular Proteomics13 citations Open access
Semantic Scholar
Everolimus in combination with mycophenolate mofetil as pre- and post-transplantation immunosuppression after nonmyeloablative hematopoietic stem cell transplantation in canine littermates.
Christoph Machka, S. Lange, J. Werner, R. Wacke +8 more
2014Biology of Blood and Marrow Transplantation13 citations Open access
Semantic Scholar
Combined Application of Pan-AKT Inhibitor MK-2206 and BCL-2 Antagonist Venetoclax in B-Cell Precursor Acute Lymphoblastic Leukemia
A. Richter, Elisabeth Fischer, Clemens Holz, Julia Schulze +7 more
2021International Journal of Molecular Sciences11 citations Open access
Semantic Scholar
Engraftment Efficiency after Intra-Bone Marrow versus Intravenous Transplantation of Bone Marrow Cells in a Canine Nonmyeloablative Dog Leukocyte Antigen-Identical Transplantation Model.
S. Lange, Anne Steder, D. Killian, G. Knuebel +8 more
2017Biology of Blood and Marrow Transplantation11 citations Open access
Semantic Scholar
Combined BCL-2 and PI3K/AKT Pathway Inhibition in KMT2A-Rearranged Acute B-Lymphoblastic Leukemia Cells
Clemens Holz, S. Lange, A. Sekora, G. Knuebel +4 more
2023International Journal of Molecular Sciences10 citations Open access
Semantic Scholar
The Molecular Subtype of Adult Acute Lymphoblastic Leukemia Samples Determines the Engraftment Site and Proliferation Kinetics in Patient-Derived Xenograft Models
A. Richter, C. Roolf, A. Sekora, G. Knuebel +11 more
2022Cells10 citations Open access
Semantic Scholar
Generation of an iPSC line (AKOSi006-A) from fibroblasts of a NPC1 patient, carrying the homozygous mutation p.I1061T (c.3182 T > C) and a control iPSC line (AKOSi007-A) using a non-integrating Sendai virus system.
Christin Völkner, Maik Liedtke, Janine Petters, K. Huth +6 more
2020Stem Cell Research7 citations Open access
Semantic Scholar
Upfront denileukin diftitox as in vivo regulatory T-cell depletion in order to enhance vaccination effects in a canine allogeneic hematopoietic stem cell transplantation model.
Anne Knueppel, S. Lange, S. Altmann, A. Sekora +5 more
2012Veterinary Immunology and Immunopathology6 citations
Semantic Scholar
Generation of an iPSC line (AKOSi004-A) from fibroblasts of a female adult NPC1 patient, carrying the compound heterozygous mutation p.Val1023Serfs*15/p.Gly992Arg and of an iPSC line (AKOSi005-A) from a female adult control individual.
Christin Völkner, Maik Liedtke, Janine Petters, J. Lukas +6 more
2020Stem Cell Research5 citations Open access
Semantic Scholar
Graft-versus-Host Disease in a Dog After Reduced-intensity Hematopoietic Stem Cell Transplantation from a DLA-identical Littermate.
S. Schaefer, J. Werner, S. Lange, Christoph Machka +7 more
2016In Vivo5 citations
Semantic Scholar
Distribution changes of epithelial dendritic cells in canine cornea and mucous membranes related to hematopoietic stem cell transplantation.
D. Killian, Maria Reichard, Anne Knueppel, S. Lange +6 more
2013In Vivo4 citations
Semantic Scholar
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
Luisa Brock, Lina Benzien, Sandra V. Lange, Maja Huehns +7 more
2025Molecular Oncology3 citations Open access
Semantic Scholar
Ultradeep targeted sequencing reveals low allele frequencies of somatic JAK2 and MPL variants in patients with abdominal vein thromboses: results of an ongoing prospective prevalence study in Mecklenburg-West Pomerania
Luise Grunwald, C. Grosse-Thie, S. Sender, G. Knuebel +5 more
2020Biomarker Research3 citations Open access
Semantic Scholar
Generation of induced pluripotent stem cell lines AKOSi002-A and AKOSi003-A from symptomatic female adults with Wilson disease.
Janine Petters, Chiara Cimmaruta, K. Iwanov, Matthew L. Chang +7 more
2020Stem Cell Research3 citations Open access
Semantic Scholar
Engraftment effects after intra-bone marrow versus intravenous allogeneic stem cell transplantation in a reduced intensity conditioning DLA-identical canine model: Intra-bone marrow versus intravenous allogeneic HSCT in canines.
S. Schaefer, S. Lange, J. Werner, Christoph Machka +8 more
2021Transplantation and Cellular Therapy2 citations Open access
Semantic Scholar
Kinetics of Langerhans cell chimerism in the skin of dogs following 2 Gy TBI allogeneic hematopoietic stem cell transplantation
S. Peters, C. Junghanss, Anne Knueppel, H. Murua Escobar +7 more
2016BMC Hematology2 citations Open access
Semantic Scholar
Intra-Bone Marrow Transplantation of CD34+ Enriched Grafts Following a Non-Myeloablative Conditioning Allows Successful Engraftment In DLA-Identical Canine Litters.
Anne Knueppel, D. Killian, S. Lange, H. Vogel +7 more
20102 citations
Semantic Scholar
Venetoclax resistance in preclinical KMT2A-rearranged acute lymphoblastic leukemia models is characterized by high inter- and intra-model heterogeneity
A. Richter, Lea Kinsky, Sandra V. Lange, N. Trakooljul +11 more
2025npj Precision Oncology1 citations Open access
Semantic Scholar
Comparative Analyses of Targeted Myeloid Cancer Next-Generation Sequencing Panel in Fresh Blood, Bone Marrow and FFPE Material
Andrea Daniela Hobeck, Sophia Wendt, S. Krohn, G. Knuebel +4 more
2024International Journal of Molecular Sciences1 citations Open access
Semantic Scholar
Hypomethylating Agents and Casein Kinase 2 Inhibitor Act Synergistic and Reveal Significant Anti-Leukemic Effects in Acute Lymphoblastic Leukemia Cells
C. Roolf, A. Richter, Christoph Konkolefski, Y. Khodamoradi +9 more
20161 citations
Semantic Scholar
Engraftment Effects of Intra Bone Marrow Compared to Intravenous Transplantation of Allogeneic Hematopoietic Stem Cells Following a Reduced Intensity Conditioning in a DLA-Identical Canine Littermate Model
J. Werner, S. Schaefer, S. Lange, Christoph Machka +8 more
20141 citations
Semantic Scholar
Ultradeep targeted sequencing reveals low allele frequencies of somatic JAK2 and MPL variants in patients with abdominal vein thromboses: results of an ongoing prospective prevalence study in Mecklenburg-West Pomerania
Luise Grunwald, C. Grosse-Thie, S. Sender, G. Knuebel +5 more
2020Biomarker Research0 citations Open access
Semantic Scholar
Generation of iPSCs for Rare Diseases
Janine Petters, A. Rolfs, A. Hermann, M. Frech +7 more
20200 citations
Semantic Scholar
Additional file 2: of Decitabine demonstrates antileukemic activity in B cell precursor acute lymphoblastic leukemia with MLL rearrangements
C. Roolf, A. Richter, Christoph Konkolefski, G. Knuebel +7 more
20180 citations
Semantic Scholar
Impact of Infusion Rate on the Early Engraftment Following Allogeneic Intra Bone Marrow Infusion of Hematopoietic Stem Cells in a Canine DLA-Identical Reduced Intensity Transplantation Model
S. Schaefer, J. Werner, S. Lange, K. Neumann +8 more
20150 citations
Semantic Scholar

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