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U. Pirvola · SciRah

Researcher profile · Semantic Scholar

U. Pirvola

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U. Pirvola — researcher profile on SciRah

h-index: 40
Works: 78
Citations: 8,263

Most-cited papers

The K+/Cl− co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation
C. Rivera, J. Voipio, J. A. Payne, E. Ruusuvuori +5 more
1999Nature2,183 citations
Semantic Scholar
Histamine-immunoreactive nerve fibers in the rat brain.
P. Panula, U. Pirvola, S. Auvinen, M. Airaksinen
1989Neuroscience647 citations
Semantic Scholar
Rescue of Hearing, Auditory Hair Cells, and Neurons by CEP-1347/KT7515, an Inhibitor of c-Jun N-Terminal Kinase Activation
U. Pirvola, Xing-Qun Liang, J. Virkkala, M. Saarma +4 more
2000Journal of Neuroscience333 citations Open access
Semantic Scholar
Expression patterns of neurotrophin and their receptor mRNAs in the rat inner ear.
J. Ylikoski, U. Pirvola, M. Moshnyakov, Jaan Palgi +2 more
1993Hearing Research316 citations
Semantic Scholar
FGFR1 is required for the development of the auditory sensory epithelium.
U. Pirvola, J. Ylikoski, R. Trokovic, J. Hébert +2 more
2002Neuron297 citations Open access
Semantic Scholar
Brain-derived neurotrophic factor and neurotrophin 3 mRNAs in the peripheral target fields of developing inner ear ganglia.
U. Pirvola, J. Ylikoski, J. Palgi, E. Lehtonen +2 more
1992Proceedings of the National Academy of Sciences of the United States of America296 citations Open access
Semantic Scholar
A histamine-containing neuronal system in human brain.
P. Panula, M. Airaksinen, U. Pirvola, E. Kotilainen
1990Neuroscience250 citations
Semantic Scholar
Expression and function of FGF10 in mammalian inner ear development
S. Pauley, Tracy J. Wright, U. Pirvola, D. Ornitz +2 more
2003Developmental Dynamics246 citations Open access
Semantic Scholar
Mutations in a novel gene with transmembrane domains underlie Usher syndrome type 3.
T. Joensuu, R. Hämäläinen, Bo Yuan, Cheryl K. Johnson +8 more
2001American Journal of Human Genetics225 citations Open access
Semantic Scholar
Coordinated expression and function of neurotrophins and their receptors in the rat inner ear during target innervation.
U. Pirvola, Urmas Arumäe, M. Moshnyakov, J. Palgi +2 more
1994Hearing Research214 citations
Semantic Scholar
Guinea pig auditory neurons are protected by glial cell line-derived growth factor from degeneration after noise trauma.
Jukka Ylikoski, U. Pirvola, J. Virkkala, P. Suvanto +5 more
1998Hearing Research203 citations
Semantic Scholar
FGFR1 is independently required in both developing mid‐ and hindbrain for sustained response to isthmic signals
R. Trokovic, N. Trokovic, Sanna Hernesniemi, U. Pirvola +5 more
2003EMBO Journal201 citations Open access
Semantic Scholar
Making and breaking the innervation of the ear: neurotrophic support during ear development and its clinical implications
Bernd Fritzsch, U. Pirvola, J. Ylikoski
1999Cell and Tissue Research171 citations
Semantic Scholar
The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear
Johanna Mantela, Zhe Jiang, J. Ylikoski, Bernd Fritzsch +2 more
2005Development145 citations Open access
Semantic Scholar
Transcutaneous vagus nerve stimulation in tinnitus: a pilot study
Jarmo Lehtimäki, Petteri Hyvärinen, M. Ylikoski, Mikael Bergholm +5 more
2013Acta Oto-Laryngologica115 citations
Semantic Scholar
Rescue and Regrowth of Sensory Nerves Following Deafferentation by Neurotrophic Factors
R. Altschuler, Y. Cho, J. Ylikoski, U. Pirvola +2 more
1999Annals of the New York Academy of Sciences115 citations Open access
Semantic Scholar
Blockade of c-Jun N-terminal kinase pathway attenuates gentamicin-induced cochlear and vestibular hair cell death.
J. Ylikoski, Xing-Qun Liang, J. Virkkala, U. Pirvola
2002Hearing Research114 citations
Semantic Scholar
Brn3c null mutant mice show long-term, incomplete retention of some afferent inner ear innervation
M. Xiang, A. Maklad, U. Pirvola, Bernd Fritzsch
2003BMC Neuroscience112 citations Open access
Semantic Scholar
The site of action of neuronal acidic fibroblast growth factor is the organ of Corti of the rat cochlea.
U. Pirvola, Yi-Hai Cao, C. Oellig, Suo-Qiang Zhai +2 more
1995Proceedings of the National Academy of Sciences of the United States of America111 citations Open access
Semantic Scholar
p19Ink4d and p21Cip1 Collaborate to Maintain the Postmitotic State of Auditory Hair Cells, Their Codeletion Leading to DNA Damage and p53-Mediated Apoptosis
Heidi Laine, Angelika Doetzlhofer, Johanna Mantela, J. Ylikoski +4 more
2007Journal of Neuroscience96 citations Open access
Semantic Scholar
Distribution of histamine in the cockroach brain and visual system: An immunocytochemical and biochemical study
U. Pirvola, L. Tuomisto, A. Yamatodani, P. Panula
1988The Journal of comparative neurology96 citations
Semantic Scholar
Fgf9 signaling regulates inner ear morphogenesis through epithelial-mesenchymal interactions.
U. Pirvola, Xiu-Qin Zhang, Johanna Mantela, D. Ornitz +1 more
2004Developmental Biology93 citations Open access
Semantic Scholar
Neurotrophins and their receptors in rat peripheral trigeminal system during maxillary nerve growth
Urmas Arumäe, U. Pirvola, J. Palgi, TR Kiema +4 more
1993Journal of Cell Biology83 citations Open access
Semantic Scholar
Non-invasive vagus nerve stimulation reduces sympathetic preponderance in patients with tinnitus
J. Ylikoski, Jarmo Lehtimäki, U. Pirvola, A. Mäkitie +3 more
2017Acta Oto-Laryngologica79 citations Open access
Semantic Scholar
Otologic consequences of blast exposure: a finnish case study of a shopping mall bomb explosion
R. Mrena, R. Pääkkönen, L. Bäck, U. Pirvola +1 more
2004Acta Oto-Laryngologica77 citations
Semantic Scholar
Cell cycle regulation in the inner ear sensory epithelia: role of cyclin D1 and cyclin-dependent kinase inhibitors.
Heidi Laine, M. Sulg, A. Kirjavainen, U. Pirvola
2010Developmental Biology74 citations Open access
Semantic Scholar
Prox1 interacts with Atoh1 and Gfi1, and regulates cellular differentiation in the inner ear sensory epithelia.
A. Kirjavainen, M. Sulg, F. Heyd, K. Alitalo +4 more
2008Developmental Biology74 citations Open access
Semantic Scholar
Expression of neurotrophins and Trk receptors in the developing, adult, and regenerating avian cochlea.
U. Pirvola, F. Hallböök, Xing-Qun Liang, J. Virkkala +2 more
1997Journal of Neurobiology70 citations
Semantic Scholar
The ototoxic interaction of styrene and noise.
A. Mäkitie, U. Pirvola, I. Pyykkö, Hisataka Sakakibara +2 more
2003Hearing Research67 citations
Semantic Scholar
How to Bury the Dead: Elimination of Apoptotic Hair Cells from the Hearing Organ of the Mouse
T. Anttonen, I. Belevich, A. Kirjavainen, Maarja Laos +3 more
2014Journal of the Association for Research in Otolaryngology66 citations Open access
Semantic Scholar
Characteristics of acute acoustical trauma in the Finnish Defence Forces
R. Mrena, S. Savolainen, U. Pirvola, J. Ylikoski
2004International Journal of Audiology65 citations
Semantic Scholar
Neurotrophic Factors in the Auditory Periphery
Xing-Qun Liang, U. Pirvola, M. Saarma, Jukka Ylikoski
1999Annals of the New York Academy of Sciences52 citations
Semantic Scholar
The Rho GTPase Cdc42 regulates hair cell planar polarity and cellular patterning in the developing cochlea
A. Kirjavainen, Maarja Laos, T. Anttonen, U. Pirvola
2015Biology Open50 citations Open access
Semantic Scholar
Immunohistochemical demonstration of neuroactive substances in the inner ear of rat and guinea pig.
J. Ylikoski, U. Pirvola, O. Häppölä, P. Panula +1 more
1989Acta Oto-Laryngologica50 citations
Semantic Scholar
Stress and Tinnitus; Transcutaneous Auricular Vagal Nerve Stimulation Attenuates Tinnitus-Triggered Stress Reaction
J. Ylikoski, M. Markkanen, U. Pirvola, Jarmo Lehtimäki +4 more
2020Frontiers in Psychology48 citations Open access
Semantic Scholar
Deficiency of the ER-stress-regulator MANF triggers progressive outer hair cell death and hearing loss
A. Herranen, Kuu Ikäheimo, Tuuli Lankinen, Emmi Pakarinen +4 more
2020Cell Death and Disease48 citations Open access
Semantic Scholar
Acidic FGF and FGF Receptors are Specifically Expressed in Neurons of Developing and Adult Rat Dorsal Root Ganglia
C. Oellig, U. Pirvola, L. Taylor, R. Elde +2 more
1995European Journal of Neuroscience48 citations
Semantic Scholar
Histamine-immunoreactive nerve fibers in the mammalian spinal cord.
P. Panula, G. Flu ̈gge, E. Fuchs, U. Pirvola +2 more
1989Brain Research46 citations
Semantic Scholar
Spatiotemporal development of cochlear innervation and hair cell differentiation in the rat.
U. Pirvola, E. Lehtonen, J. Ylikoski
1991Hearing Research41 citations
Semantic Scholar
Cdc42-dependent structural development of auditory supporting cells is required for wound healing at adulthood
T. Anttonen, A. Kirjavainen, I. Belevich, Maarja Laos +4 more
2012Scientific Reports40 citations Open access
Semantic Scholar
Apoptosis in Auditory Brainstem Neurons after a Severe Noise Trauma of the Organ of Corti: Intracochlear GDNF Treatment Reduces the Number of Apoptotic Cells
A. Aarnisalo, U. Pirvola, Xing-Qun Liang, Josef M. Miller +1 more
2000ORL40 citations
Semantic Scholar
Histaminelike immunoreactive neurons innervating putative neurohaemal areas and central neuropil in the thoraco‐abdominal ganglia of the flies Drosophila and Calliphora
Dick R. Nässel, U. Pirvola, P. Panula
1990The Journal of comparative neurology39 citations
Semantic Scholar
Nonerythroid spectrin (fodrin) is a prominent component of the cochlear hair cells.
J. Ylikoski, U. Pirvola, O. Närvänen, I. Virtanen
1990Hearing Research38 citations
Semantic Scholar
Occupational noise-induced hearing loss reports and tinnitus in Finland
R. Mrena, M. Ylikoski, A. Mäkitie, U. Pirvola +1 more
2007Acta Oto-Laryngologica36 citations
Semantic Scholar
Neurotrophic factors during inner ear development.
U. Pirvola, J. Ylikoski
2003Current Topics in Developmental Biology35 citations
Semantic Scholar
Hyperbaric oxygen therapy seems to enhance recovery from acute acoustic trauma
Jukka Ylikoski, R. Mrena, A. Mäkitie, J. Kuokkanen +2 more
2008Acta Oto-Laryngologica34 citations
Semantic Scholar
Restrictions in Cell Cycle Progression of Adult Vestibular Supporting Cells in Response to Ectopic Cyclin D1 Expression
Heidi Loponen, J. Ylikoski, J. Albrecht, U. Pirvola
2011PLoS ONE32 citations Open access
Semantic Scholar
The "toughening" phenomenon in rat's auditory organ.
M. Pukkila, S. Zhai, J. Virkkala, U. Pirvola +1 more
1997Acta oto-laryngologica. Supplementum32 citations
Semantic Scholar
Distribution of F-actin and fodrin in the hair cells of the guinea pig cochlea as revealed by confocal fluorescence microscopy.
J. Ylikoski, U. Pirvola, E. Lehtonen
1992Hearing Research31 citations
Semantic Scholar
Coupling the cell cycle to development and regeneration of the inner ear.
T. Schimmang, U. Pirvola
2013Seminars in Cell and Developmental Biology28 citations Open access
Semantic Scholar

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J. Ylikoski×26
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M. Saarma×6
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Jukka Ylikoski×6
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Bernd Fritzsch×5

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A. Kirjavainen×5

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Urmas Arumäe×4

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Mart Saarma — researcher profile on SciRah

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M. Airaksinen — researcher profile on SciRah