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K. Ugen · SciRah

Researcher profile · Semantic Scholar

K. Ugen

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K. Ugen — researcher profile on SciRah

h-index: 46
Works: 168
Citations: 9,851

Most-cited papers

Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
D. Morgan, D. Diamond, P. E. Gottschall, K. Ugen +11 more
2000Nature1,405 citations
Semantic Scholar
Phase I trial of interleukin-12 plasmid electroporation in patients with metastatic melanoma.
A. Daud, R. Deconti, S. Andrews, P. Urbas +7 more
2008Journal of Clinical Oncology679 citations Open access
Semantic Scholar
A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease.
D. Morgan, D. Diamond, P. E. Gottschall, K. Ugen +11 more
2000Nature648 citations
Semantic Scholar
Intracranially Administered Anti-Αβ Antibodies Reduce β-Amyloid Deposition by Mechanisms Both Independent of and Associated with Microglial Activation
D. Wilcock, G. Dicarlo, D. Henderson, J. Jackson +4 more
2003Journal of Neuroscience259 citations Open access
Semantic Scholar
A synthetic consensus anti–spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates
K. Muthumani, D. Falzarano, E. Reuschel, Colleen Tingey +22 more
2015Science Translational Medicine235 citations Open access
Semantic Scholar
Microglial activation facilitates A B plaque removal following intracranial antiA B antibody administration
D. Wilcock, S. Munireddy, A. Rosenthal, K. Ugen +2 more
2004190 citations
Semantic Scholar
Intracranially administered anti-Abeta antibodies reduce beta-amyloid deposition by mechanisms both independent of and associated with microglial activation.
D. Wilcock, G. Dicarlo, D. Henderson, J. Jackson +4 more
2003Journal of Neuroscience159 citations
Semantic Scholar
Microglial activation facilitates Abeta plaque removal following intracranial anti-Abeta antibody administration.
D. Wilcock, S. Munireddy, A. Rosenthal, K. Ugen +2 more
2004Neurobiology of Disease131 citations
Semantic Scholar
Electroporation for targeted gene transfer
L. Heller, K. Ugen, R. Heller
2005Expert Opinion on Drug Delivery130 citations
Semantic Scholar
In vivo protection against ZIKV infection and pathogenesis through passive antibody transfer and active immunisation with a prMEnv DNA vaccine
K. Muthumani, B. Griffin, Sangya Agarwal, S. Kudchodkar +25 more
2016npj Vaccines129 citations Open access
Semantic Scholar
T-cell responses induced in normal volunteers immunized with a DNA-based vaccine containing HIV-1 env and rev
R. Macgregor, R. Ginsberg, K. Ugen, Y. Baine +5 more
2002AIDS (London)104 citations Open access
Semantic Scholar
Number of Aβ Inoculations in APP+PS1 Transgenic Mice Influences Antibody Titers, Microglial Activation, and Congophilic Plaque Levels
D. Wilcock, M. N. Gordon, K. Ugen, P. E. Gottschall +8 more
200198 citations
Semantic Scholar
DNA Vaccines against Human Immunodeficiency Virus Type 1 in the Past Decade
Malavika S. Giri, K. Ugen, D. Weiner
2004Clinical Microbiology Reviews96 citations Open access
Semantic Scholar
Rapid and Long-Term Immunity Elicited by DNA-Encoded Antibody Prophylaxis and DNA Vaccination Against Chikungunya Virus
Karuppiah Muthumani, P. Block, Seleeke Flingai, N. Muruganantham +14 more
2016Journal of Infectious Diseases86 citations Open access
Semantic Scholar
Modulation of Antigen-Specific Humoral Responses in Rhesus Macaques by Using Cytokine cDNAs as DNA Vaccine Adjuvants
Jong J. Kim, Joo-sung Yang, T. VanCott, Daniel J. Lee +5 more
2000Journal of Virology76 citations Open access
Semantic Scholar
Regression of subcutaneous B16 melanoma tumors after intratumoral delivery of an IL-15-expressing plasmid followed by in vivo electroporation
K. Ugen, Michele A. Kutzler, B. Marrero, Jeffrey Westover +3 more
2006Cancer Gene Therapy75 citations Open access
Semantic Scholar
Anti-Human α-Synuclein N-Terminal Peptide Antibody Protects against Dopaminergic Cell Death and Ameliorates Behavioral Deficits in an AAV-α-Synuclein Rat Model of Parkinson’s Disease
M. Shahaduzzaman, K. Nash, C. Hudson, M. Sharif +7 more
2015PLoS ONE73 citations Open access
Semantic Scholar
Plasmids encoding the mucosal chemokines CCL27 and CCL28 are effective adjuvants in eliciting antigen-specific immunity in vivo
Michele A. Kutzler, K. Kraynyak, S. Nagle, Rose Parkinson +6 more
2009Gene Therapy67 citations Open access
Semantic Scholar
Therapeutic immunization of HIV-infected chimpanzees using HIV-1 plasmid antigens and interleukin-12 expressing plasmids
J. Boyer, A. Cohen, K. Ugen, Rebecca L. Edgeworth +8 more
2000AIDS (London)63 citations Open access
Semantic Scholar
Electroporation Mediated Delivery of a Naked DNA Plasmid Expressing VEGF to the Porcine Heart Enhances Protein Expression
William G. Marshall, Brian A Boone, Jose D. Burgos, Sylvia I. Gografe +10 more
2009Gene Therapy54 citations Open access
Semantic Scholar
Overcoming antigen masking of anti-amyloidbeta antibodies reveals breaking of B cell tolerance by virus-like particles in amyloidbeta immunized amyloid precursor protein transgenic mice
Qing-You Li, Chuan-Hai Cao, B. Chackerian, J. Schiller +3 more
2004BMC Neuroscience54 citations Open access
Semantic Scholar
Potent cross-group neutralization of primary human immunodeficiency virus isolates with monoclonal antibodies--implications for acquired immunodeficiency syndrome vaccine.
F. Ferrantelli, M. Kitabwalla, R. Rasmussen, Chuan-Hai Cao +8 more
2004Journal of Infectious Diseases50 citations
Semantic Scholar
Improvement of a low pH antigen-antibody dissociation procedure for ELISA measurement of circulating anti-Aβ antibodies
Qing-You Li, M. Gordon, Chuan-Hai Cao, K. Ugen +1 more
2007BMC Neuroscience49 citations Open access
Semantic Scholar
Plasmid vaccination of stable HIV-positive subjects on antiviral treatment results in enhanced CD8 T-cell immunity and increased control of viral "blips".
R. Macgregor, J. Boyer, K. Ugen, P. Tebas +5 more
2005Vaccine49 citations
Semantic Scholar
Duration and Specificity of Humoral Immune Responses in Mice Vaccinated with the Alzheimer's Disease-Associated β-Amyloid 1-42 Peptide
Chad A. Dickey, Dave Morgan, S. Kudchodkar, David B. Weiner +4 more
2001DNA and Cell Biology47 citations
Semantic Scholar
Optimized and enhanced DNA plasmid vector based in vivo construction of a neutralizing anti-HIV-1 envelope glycoprotein Fab
K. Muthumani, Seleeke Flingai, Megan C. Wise, Colleen Tingey +2 more
2013Human Vaccines & Immunotherapeutics45 citations Open access
Semantic Scholar
Protection from immunodeficiency virus challenges in rhesus macaques by multicomponent DNA immunization.
J.Joseph Kim, Joo-Sung Yang, Liesl K. Nottingham, Daniel J. Lee +6 more
2001Virology43 citations Open access
Semantic Scholar
Short-term β-amyloid vaccinations do not improve cognitive performance in cognitively impaired APP+PS1 mice
L. Austin, G. Arendash, M. Gordon, D. Diamond +4 more
200342 citations
Semantic Scholar
A Gag-Pol/Env-Rev SIV239 DNA vaccine improves CD4 counts, and reduce viral loads after pathogenic intrarectal SIV(mac)251 challenge in rhesus Macaques.
K. Muthumani, M. Bagarazzi, D. Conway, Daniel S. Hwang +9 more
2003Vaccine41 citations
Semantic Scholar
Evaluation of an α synuclein sensitized dendritic cell based vaccine in a transgenic mouse model of Parkinson disease
K. Ugen, Xiao-Yang Lin, Ge Bai, Zhanhua Liang +5 more
2015Human Vaccines & Immunotherapeutics39 citations Open access
Semantic Scholar
Novel prostate cancer immunotherapy with a DNA-encoded anti-prostate-specific membrane antigen monoclonal antibody
K. Muthumani, L. Marnin, S. Kudchodkar, A. Perales-Puchalt +12 more
2017Cancer Immunology and Immunotherapy37 citations Open access
Semantic Scholar
A b peptide vaccination prevents memory loss in an animal model of Alzheimer ' s disease
Dave Morgan, D. Diamond, Paul E. Gottschall, K. Ugen +11 more
200134 citations
Semantic Scholar
Nonstructural Protein 2 (nsP2) of Chikungunya Virus (CHIKV) Enhances Protective Immunity Mediated by a CHIKV Envelope Protein Expressing DNA Vaccine
H. Bao, Aarti A. Ramanathan, Omkar Kawalakar, S. G. Sundaram +8 more
2013Viral immunology32 citations Open access
Semantic Scholar
Novel and enhanced anti-melanoma DNA vaccine targeting the tyrosinase protein inhibits myeloid-derived suppressor cells and tumor growth in a syngeneic prophylactic and therapeutic murine model
Jian Yan, Colleen Tingey, R. Lyde, T. C. Gorham +12 more
2014Cancer Gene Therapy31 citations Open access
Semantic Scholar
Complete regression of established subcutaneous B16 murine melanoma tumors after delivery of an HIV-1 Vpr-expressing plasmid by in vivo electroporation.
Andrea N. McCray, K. Ugen, K. Muthumani, Jong J. Kim +2 more
2006Molecular Therapy31 citations Open access
Semantic Scholar
Mapping of immune responses following wild-type and mutant ABeta42 plasmid or peptide vaccination in different mouse haplotypes and HLA Class II transgenic mice.
Michele A. Kutzler, Chuan-Hai Cao, Yun Bai, Hui-Qin Dong +7 more
2006Vaccine31 citations
Semantic Scholar
Human single chain Fv antibodies and a complementarity determining region-derived peptide binding to amyloid-beta 1-42.
K. Manoutcharian, G. Acero, M. Munguía, B. Becerril +7 more
2004Neurobiology of Disease25 citations Open access
Semantic Scholar
A novel synthetic DNA vaccine elicits protective immune responses against Powassan virus
Hyeree Choi, S. Kudchodkar, Michelle Ho, E. Reuschel +10 more
2020PLoS Neglected Tropical Diseases24 citations Open access
Semantic Scholar
Epitope mapping and neuroprotective properties of a human single chain FV antibody that binds an internal epitope of amyloid-beta 1-42.
R. Solórzano-Vargas, V. Vasilevko, G. Acero, K. Ugen +7 more
2008Molecular Immunology23 citations
Semantic Scholar
Short-term beta-amyloid vaccinations do not improve cognitive performance in cognitively impaired APP + PS1 mice.
L. Austin, G. Arendash, M. Gordon, D. Diamond +4 more
2003Behavioral Neuroscience23 citations
Semantic Scholar
HIV-1 Vpr: enhancing sensitivity of tumors to apoptosis.
K. Muthumani, A. Y. Choo, Daniel S. Hwang, K. Ugen +1 more
2004Current Drug Delivery19 citations
Semantic Scholar
Amyloid-beta peptide-specific single chain Fv antibodies isolated from an immune phage display library.
K. Manoutcharian, G. Acero, M. Munguía, J. Montero +4 more
2003Journal of Neuroimmunology19 citations
Semantic Scholar
Non-contact helium-based plasma for delivery of DNA vaccines
R. Connolly, Taryn Chapman, A. Hoff, Michele A. Kutzler +2 more
2012Human Vaccines & Immunotherapeutics18 citations Open access
Semantic Scholar
Virus-like Peptide Vaccines Against Aß N-terminal or C-Terminal Domains Reduce Amyloid Deposition in APP Transgenic Mice without Addition of Adjuvant
Qing-You Li, M. Gordon, B. Chackerian, Jennifer Alamed +2 more
2010Journal of Neuroimmune Pharmacology18 citations
Semantic Scholar
Anti-tumor activity mediated by protein and peptide transduction of HIV viral protein R (Vpr)
K. Muthumani, Vance M. Lambert, Mayilvahanan Shanmugam, K. Thieu +6 more
2009Cancer Biology & Therapy18 citations Open access
Semantic Scholar
Enhancement of anti-melanoma activity of a plasmid expressing HIV-1 Vpr delivered through in vivo electroporation
Andrea N. McCray, K. Ugen, R. Heller
2007Cancer Biology & Therapy17 citations Open access
Semantic Scholar
Phage-displayed mimotopes recognizing a biologically active anti-HIV-1 gp120 murine monoclonal antibody.
V. R. Gómez-Román, Chuan-Hai Cao, Yun Bai, H. Santamaría +5 more
2002Journal of Acquired Immune Deficiency Syndromes17 citations Open access
Semantic Scholar
Engineering of DNA vaccines using molecular adjuvant plasmids.
J. Sin, Jong J. Kim, Michael A. Chattergoon, V. Ayyavoo +4 more
2000Developments in Biologicals16 citations
Semantic Scholar
Enhancement of antigen specific humoral immune responses after delivery of a DNA plasmid based vaccine through a contact-independent helium plasma
R. Connolly, J. I. Rey, Vance M. Lambert, Garrett Wegerif +2 more
2010Vaccine15 citations Open access
Semantic Scholar
Gene-based vaccines and immunotherapeutic strategies against neurodegenerative diseases: Potential utility and limitations
Jeremy J. Kudrna, K. Ugen
2015Human Vaccines & Immunotherapeutics14 citations Open access
Semantic Scholar

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