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B. Gurda · SciRah

Researcher profile · Semantic Scholar

B. Gurda

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B. Gurda — researcher profile on SciRah

h-index: 24
Works: 50
Citations: 2,055

Most-cited papers

Structure of Adeno-Associated Virus Serotype 8, a Gene Therapy Vector
H. Nam, M. D. Lane, E. Padron, B. Gurda +7 more
2007Journal of Virology257 citations Open access
Semantic Scholar
Structural Insight into the Unique Properties of Adeno-Associated Virus Serotype 9
M. DiMattia, H. Nam, K. van Vliet, M. Mitchell +12 more
2012Journal of Virology198 citations Open access
Semantic Scholar
Structural Characterization of the Dual Glycan Binding Adeno-Associated Virus Serotype 6
R. Ng, L. Govindasamy, B. Gurda, R. McKenna +5 more
2010Journal of Virology157 citations Open access
Semantic Scholar
Identification of the Galactose Binding Domain of the Adeno-Associated Virus Serotype 9 Capsid
Christie L. Bell, B. Gurda, K. van Vliet, M. Agbandje-McKenna +1 more
2012Journal of Virology129 citations Open access
Semantic Scholar
Capsid Antibodies to Different Adeno-Associated Virus Serotypes Bind Common Regions
B. Gurda, M. DiMattia, Edward B. Miller, A. Bennett +14 more
2013Journal of Virology122 citations Open access
Semantic Scholar
Intrathecal gene therapy corrects CNS pathology in a feline model of mucopolysaccharidosis I.
Christian J. Hinderer, Peter Bell, B. Gurda, Qiang Wang +9 more
2014Molecular Therapy106 citations Open access
Semantic Scholar
Structural Studies of Adeno-Associated Virus Serotype 8 Capsid Transitions Associated with Endosomal Trafficking
H. Nam, B. Gurda, R. McKenna, M. Potter +4 more
2011Journal of Virology106 citations Open access
Semantic Scholar
Mapping a Neutralizing Epitope onto the Capsid of Adeno-Associated Virus Serotype 8
B. Gurda, Christina Raupp, Ruth Popa-Wagner, Matthias Naumer +6 more
2012Journal of Virology97 citations Open access
Semantic Scholar
Human Bocavirus Capsid Structure: Insights into the Structural Repertoire of the Parvoviridae
B. Gurda, Kristin N. Parent, Heather Bladek, R. Sinkovits +8 more
2010Journal of Virology90 citations Open access
Semantic Scholar
Structural Insights into Adeno-Associated Virus Serotype 5
L. Govindasamy, M. DiMattia, B. Gurda, Sujata Halder +5 more
2013Journal of Virology88 citations Open access
Semantic Scholar
Neonatal Systemic AAV Induces Tolerance to CNS Gene Therapy in MPS I Dogs and Nonhuman Primates.
Christian J. Hinderer, Peter Bell, J. Louboutin, Yanqing Zhu +13 more
2015Molecular Therapy84 citations Open access
Semantic Scholar
Evaluation of AAV-mediated Gene Therapy for Central Nervous System Disease in Canine Mucopolysaccharidosis VII
B. Gurda, A. de Guilhem de Lataillade, Peter Bell, Yanqing Zhu +16 more
2015Molecular Therapy76 citations Open access
Semantic Scholar
Adeno-Associated Virus Serotype 1 (AAV1)- and AAV5-Antibody Complex Structures Reveal Evolutionary Commonalities in Parvovirus Antigenic Reactivity
Yu-Shan Tseng, B. Gurda, P. Chipman, R. McKenna +7 more
2014Journal of Virology62 citations Open access
Semantic Scholar
The Threefold Protrusions of Adeno-Associated Virus Type 8 Are Involved in Cell Surface Targeting as Well as Postattachment Processing
Christina Raupp, Matthias Naumer, O. Müller, B. Gurda +2 more
2012Journal of Virology61 citations Open access
Semantic Scholar
Examining the cross-reactivity and neutralization mechanisms of a panel of mAbs against adeno-associated virus serotypes 1 and 5.
C. Harbison, Wendy S. Weichert, B. Gurda, J. Chiorini +2 more
2012Journal of General Virology53 citations Open access
Semantic Scholar
Structure of an Enteric Pathogen, Bovine Parvovirus
S. Kailasan, Sujata Halder, B. Gurda, Heather Bladek +4 more
2014Journal of Virology48 citations Open access
Semantic Scholar
Liver-directed gene therapy corrects cardiovascular lesions in feline mucopolysaccharidosis type I
Christian J. Hinderer, Peter Bell, B. Gurda, Qiang Wang +9 more
2014Proceedings of the National Academy of Sciences of the United States of America45 citations Open access
Semantic Scholar
Cerebrospinal Fluid Calbindin D Concentration as a Biomarker of Cerebellar Disease Progression in Niemann-Pick Type C1 Disease
Allison M. Bradbury, J. Bagel, M. Sampson, N. Farhat +10 more
2016Journal of Pharmacology and Experimental Therapeutics33 citations Open access
Semantic Scholar
Adeno-associated virus serotypes 9 and rh10 mediate strong neuronal transduction of the dog brain
Gary P. Swain, Maria Prociuk, J. Bagel, Patricia A O'Donnell +6 more
2013Gene Therapy33 citations Open access
Semantic Scholar
A Review of Gene Therapy in Canine and Feline Models of Lysosomal Storage Disorders
Allison M. Bradbury, B. Gurda, Margret L. Casal, K. Ponder +2 more
2015Human Gene Therapy Clinical Development32 citations Open access
Semantic Scholar
Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 9.
M. Mitchell, H. Nam, Adam C. Carter, A. McCall +11 more
2009Acta Crystallographica. Section F : Structural Biology and Crystallization Communications30 citations Open access
Semantic Scholar
Mapping the Structural Determinants Responsible for Enhanced T Cell Activation to the Immunogenic Adeno-Associated Virus Capsid from Isolate Rhesus 32.33
Lauren E. Mays, Lili Wang, Rebeca M. Tenney, Peter Bell +7 more
2013Journal of Virology29 citations Open access
Semantic Scholar
Large animal models contribute to the development of therapies for central and peripheral nervous system dysfunction in patients with lysosomal storage diseases.
B. Gurda, C. Vite
2019Human Molecular Genetics28 citations Open access
Semantic Scholar
Canine and Feline Models of Human Genetic Diseases and Their Contributions to Advancing Clinical Therapies
B. Gurda, Allison M. Bradbury, C. Vite
2017The Yale Journal of Biology and Medicine28 citations
Semantic Scholar
Electronic Reprint Structural Biology and Crystallization Communications Production, Purification and Preliminary X-ray Crystallographic Studies of Adeno-associated Virus Serotype 7 Structural Biology and Crystallization Communications Production, Purification and Preliminary X-ray Crystallographic
Acta Crystallographica Section, H. Einspahr, J. Guss, O. Quesada +8 more
19 citations
Semantic Scholar
Wnt10b and Dkk-1 gene therapy differentially influenced trabecular bone architecture, soft tissue integrity and osteophytosis in a skeletally mature rat model of osteoarthritis
J. Mason, B. Gurda, K. Hankenson, L. Harper +3 more
2016Connective Tissue Research14 citations Open access
Semantic Scholar
LC3 Immunostaining in the Inferior Olivary Nuclei of Cats With Niemann-Pick Disease Type C1 Is Associated With Patterned Purkinje Cell Loss
B. Gurda, J. Bagel, Samantha J. Fisher, M. Schultz +4 more
2018Journal of Neuropathology and Experimental Neurology8 citations Open access
Semantic Scholar
Delivery and evaluation of recombinant adeno-associated viral vectors in the equine distal extremity for the treatment of laminitis
J. Mason, B. Gurda, A. V. Van Wettere, J. Engiles +2 more
2016Equine Veterinary Journal6 citations Open access
Semantic Scholar
Multiple Recombinant Adeno-Associated Viral Vector Serotypes Display Persistent In Vivo Gene Expression in Vector-Transduced Rat Stifle Joints
J. Mason, B. Gurda, J. Engiles, K. Hankenson +2 more
2013Human Gene Therapy Methods6 citations Open access
Semantic Scholar
Pharmacokinetics and distribution of 2‐hydroxypropyl‐β‐cyclodextrin following a single intrathecal dose to cats
Mark L. Kao, S. Stellar, E. Solon, A. Lordi +5 more
2019Journal of Inherited Metabolic Disease4 citations Open access
Semantic Scholar
In Situ Hybridization for Detection of AAV-Mediated Gene Expression
Jacqueline E. Hunter, B. Gurda, Sea Young Yoon, Michael J. Castle +1 more
2019Methods in molecular biology4 citations
Semantic Scholar
Correction for Gurda et al., “Mapping a Neutralizing Epitope onto the Capsid of Adeno-Associated Virus Serotype 8”
B. Gurda, Christina Raupp, Ruth Popa-Wagner, Matthias Naumer +6 more
2025Journal of Virology1 citations Open access
Semantic Scholar
Evaluating the impact of systemic AAV9.cIDUA administration on brain pathology in MPS I dogs
Peter Bell, B. Gurda, Yanqing Zhu, Tracey U. Sikora +4 more
20151 citations
Semantic Scholar
Gene therapy for mucopolysaccharidosis VII: evaluation of intrathecal rAAV vectors in the canine model
B. Gurda, Ping Wang, Peter Bell, J. Bagel +11 more
20141 citations
Semantic Scholar
Chapter 1:Production and Purification of Viruses for Structural Studies
B. Gurda, M. Agbandje-McKenna
20101 citations
Semantic Scholar
Diagnosis and therapy of Niemann-Pick disease type C1- what have we learned that can help veterinary patients?
Charles H. Vite, B. Gurda, F. Porter, Margret L. Casal
2026Rare Disease and Orphan Drugs Journal0 citations Open access
Semantic Scholar
656P AAV gene therapy in the Pompe canine model demonstrates correction of the muscle and CNS disorder with immune tolerance to human GAA.
B. Byrne, M. Pope, M. Gentry, R. Sun +7 more
2024Neuromuscular Disorders0 citations
Semantic Scholar
Procédés et compositions pour vecteurs viraux évitant les anticorps
A. Asokan, M. Agbandje-McKenna, Long-Ping V. Tse, B. Gurda
20160 citations
Semantic Scholar
611. Promoter Evaluation of AAV Gene Therapy in the Central Nervous System for Feline Niemann-Pick Type C Disease
B. Gurda, Gary P. Swain, J. Bagel, Maria Prociuk +4 more
20160 citations Open access
Semantic Scholar
Intrathecal injection of lentiviral vector results in high expression in the brain of mucopolysaccharidosis VII dogs but the pattern of expression is different than for AAV9 or AAV-rh10
K. Ponder, H. Kobayashi, T. Ohashi, Sayoko Izuka +5 more
20150 citations
Semantic Scholar
Adeno-associated virus vector-mediated gene therapy can effectively treat CNS and cardiac lesions and induce immune tolerance to the therapeutic enzyme in large animal models of mucopolysaccharidosis type I
James M. Wilson, Christian J. Hinderer, Peter Bell, B. Gurda +11 more
20150 citations
Semantic Scholar
Structural annotation of pathogenic bovine Parvovirus-1
S. Kailasan, Sujata Halder, B. Gurda, Heather Bladek +4 more
20150 citations
Semantic Scholar
Virus Capsid from Isolate Rhesus 32.33 to the Immunogenic Adeno-Associated Activation Responsible for Enhanced T Cell Mapping the Structural Determinants
Kyle Mikals, H. Nam, Jian-Ping Lin, B. Gurda +4 more
20140 citations
Semantic Scholar
In vivo gene therapy of the equine distal extremity with recombinant adeno-associated viral vectors for the treatment of laminitis
J. Mason, B. Gurda, J. Engiles, James M. Wilson +1 more
20130 citations
Semantic Scholar
Liver-Directed Gene Therapy for Mucopolysaccharidosis Type I (MPS I)
B. Gurda, Peter Bell, Yanqing Zhu, Ping Wang +5 more
20120 citations
Semantic Scholar
Large Animal Models of Lysosomal Storage Diseases: Lessons on the Limits of Gene/Enzyme Therapy
M. Haskins, M. Sleeper, G. Aguirre, S. Walkley +9 more
20120 citations
Semantic Scholar
Structural Characterization of Adeno-Associated Virus Serotype 9
M. DiMattia, H. Nam, K. van Vliet, M. Mitchell +14 more
20120 citations
Semantic Scholar
Structural Studies of Adeno-Associated Virus Serotype 8 Capsid Transitions Associated with Endosomal Trafﬁcking (cid:1)
H. Nam, B. Gurda, R. McKenna, M. Potter +4 more
20110 citations
Semantic Scholar
Structure to Function Correlations for Adeno-associated Virus Serotype 1
L. Govindasamy, Edward B. Miller, B. Gurda, R. McKenna +3 more
20110 citations
Semantic Scholar
Mapping dominant antigenic regions on the capsid surfaces of adeno-associated virions
B. Gurda
20100 citations
Semantic Scholar

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