Researcher profile · Semantic Scholar

H. Whittington

h-index: 13
Works: 28
Citations: 822

Most-cited papers

Chronic Metformin Associated Cardioprotection Against Infarction: Not Just a Glucose Lowering Phenomenon
H. Whittington, A. R. Hall, C. McLaughlin, D. Hausenloy +2 more
2013Cardiovascular Drugs and Therapy108 citations Open access
Semantic Scholar
Cardioprotection in the aging, diabetic heart: the loss of protective Akt signalling.
H. Whittington, I. Harding, C. I. M. Stephenson, R. Bell +3 more
2013Cardiovascular Research97 citations Open access
Semantic Scholar
Dipeptidyl peptidase-4 inhibitors and GLP-1 reduce myocardial infarct size in a glucose-dependent manner
D. Hausenloy, H. Whittington, Abigail M. Wynne, S. Begum +4 more
2013Cardiovascular Diabetology90 citations Open access
Semantic Scholar
Slow Binding Inhibition and Mechanism of Resistance of Non-nucleoside Polymerase Inhibitors of Hepatitis C Virus
J. Hang, Yanli Yang, S. Harris, V. Leveque +11 more
2009Journal of Biological Chemistry83 citations Open access
Semantic Scholar
The Diabetic Heart: Too Sweet for Its Own Good?
H. Whittington, G. Babu, M. Mocanu, D. Yellon +1 more
2012Cardiology Research and Practice69 citations Open access
Semantic Scholar
Resolving Fine Cardiac Structures in Rats with High-Resolution Diffusion Tensor Imaging
I. Teh, D. McClymont, Rebecca A. B. Burton, M. Maguire +4 more
2016Scientific Reports57 citations Open access
Semantic Scholar
Augmentation of Creatine in the Heart
S. Zervou, H. Whittington, A. Russell, C. Lygate
2015Mini-Reviews in Medical Chemistry53 citations Open access
Semantic Scholar
Over-expression of mitochondrial creatine kinase in the murine heart improves functional recovery and protects against injury following ischaemia–reperfusion
H. Whittington, P. Ostrowski, Debra J. McAndrew, Fang Cao +8 more
2018Cardiovascular Research52 citations Open access
Semantic Scholar
Validation of diffusion tensor MRI measurements of cardiac microstructure with structure tensor synchrotron radiation imaging
I. Teh, D. McClymont, M. Zdora, H. Whittington +6 more
2017Journal of Cardiovascular Magnetic Resonance45 citations Open access
Semantic Scholar
Impaired cardiac contractile function in arginine:glycine amidinotransferase knockout mice devoid of creatine is rescued by homoarginine but not creatine
K. Faller, D. Atzler, Debra J. McAndrew, S. Zervou +10 more
2017Cardiovascular Research45 citations Open access
Semantic Scholar
Increasing creatine kinase activity protects against hypoxia / reoxygenation injury but not against anthracycline toxicity in vitro
S. Zervou, H. Whittington, P. Ostrowski, Fang Cao +4 more
2017PLoS ONE30 citations Open access
Semantic Scholar
Prospective acceleration of diffusion tensor imaging with compressed sensing using adaptive dictionaries
D. McClymont, I. Teh, H. Whittington, V. Grau +1 more
2015Magnetic Resonance in Medicine29 citations Open access
Semantic Scholar
Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism
A. Valli, M. Morotti, C. Zois, Patrick K. Albers +17 more
2019Molecular Cancer Research27 citations Open access
Semantic Scholar
Evaluation of non-Gaussian diffusion in cardiac MRI
D. McClymont, I. Teh, Eric D. Carruth, J. Omens +5 more
2016Magnetic Resonance in Medicine13 citations Open access
Semantic Scholar
Protective Effect of Creatine Elevation against Ischaemia Reperfusion Injury Is Retained in the Presence of Co-Morbidities and during Cardioplegia
H. Whittington, Debra J. McAndrew, Rebecca L. Cross, S. Neubauer +1 more
2016PLoS ONE11 citations Open access
Semantic Scholar
Subtle Role for Adenylate Kinase 1 in Maintaining Normal Basal Contractile Function and Metabolism in the Murine Heart
S. Zervou, Debra J. McAndrew, H. Whittington, H. A. Lake +7 more
2021Frontiers in Physiology7 citations Open access
Semantic Scholar
Assessing Myocardial Microstructure With Biophysical Models of Diffusion MRI
M. Farzi, D. McClymont, H. Whittington, M. Zdora +6 more
2021IEEE Transactions on Medical Imaging5 citations Open access
Semantic Scholar
4 Characterisation of Mitochondrial Morphology in the Adult Rodent Heart
S. Kalkhoran, A. R. Hall, H. Whittington, S. Davidson +2 more
2014Heart2 citations
Semantic Scholar
26 Chronic Saxagliptin Treatment in a Diabetic Rat Model Protects against Infarction Independently of its Glucose Lowering Capacity
H. Whittington, V. Sivaraman, M. Mocanu, D. Yellon
2014Heart1 citations
Semantic Scholar
222 Augmentation of creatine kinase in vitro protects against simulated ischaemia reperfusion injury
S. Zervou, H. Whittington, P. Ostrowski, Fang Cao +4 more
20170 citations Open access
Semantic Scholar
A Study of Retinal Mitochondrial Changes in Aged Diabetic (Goto-Kakizaki) Rats to Explore Possible Links with Alzheimer’s Disease
Marianne Phillips, Timothy Wong, S. Nizari, Y. Chan +3 more
20140 citations
Semantic Scholar
P683The role of nitric oxide synthase (NOS) and its essential cofactor tetrahydrobiopterin (BH4) in diabetic cardiomyopathy
Drew Duglan, R. Carnicer, Jillian N. Simon, A. Recalde +6 more
20140 citations Open access
Semantic Scholar
LOSS OF HOMOARGININE IS RESPONSIBLE FOR CARDIAC DYSFUNCTION IN CREATINE-DEFICIENT ARGININE:GLYCINE AMIDINOTRANSFERASE (AGAT) KNOCKOUT MICE
H. Whittington, D. Atzler, S. Zervou, Kme Faller +6 more
2014Heart0 citations
Semantic Scholar
229 THE IMPAIRMENT OF INNATE CARDIOPROTECTIVE SIGNALING IN THE AGED, DIABETIC RAT HEART
H. Whittington, I. Harding, C. I. M. Stephenson, R. Bell +2 more
2013Heart0 citations Open access
Semantic Scholar
The influence of age and type 2 diabetes on cardioprotective interventions against myocardial ischaemia-reperfusion injury.
H. Whittington
20130 citations
Semantic Scholar
39 Endogenous protection against myocardial ischaemia-reperfusion injury in the diabetic heart
H. Whittington, C. McLaughlin, D. Hausenloy, D. Yellon +1 more
2011Heart0 citations
Semantic Scholar
1 Slow-binding inhibition and mechanism of resistance of non-nucleoside polymerase inhibitors of hepatitis C virus
J. Hang, Yanli Yang, S. Harris, V. Leveque +11 more
20090 citations
Semantic Scholar
Quantifying Cardiac Hypertrophy using Biophysical Models of Diffusion MRI
M. Farzi, D. McClymont, H. Whittington, M. Zdora +6 more
ISMRM Annual Meeting0 citations
Semantic Scholar

D. Hausenloy

×6

I. Teh×6

D. McClymont×6

S. Neubauer×6

Debra J. McAndrew×5

H. A. Lake×5

D. Yellon×4

P. Ostrowski×4