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Abigail M. Wynne · SciRah

Researcher profile · Semantic Scholar

Abigail M. Wynne

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Abigail M. Wynne — researcher profile on SciRah

h-index: 13
Works: 26
Citations: 1,587

Most-cited papers

Transient Mitochondrial Permeability Transition Pore Opening Mediates Preconditioning-Induced Protection
D. Hausenloy, Abigail M. Wynne, M. Duchen, D. Yellon
2004Circulation384 citations Open access
Semantic Scholar
Apelin-13 and apelin-36 exhibit direct cardioprotective activity against ischemiareperfusion injury
James C. Simpkin, D. Yellon, S. Davidson, Shiang Y. Lim +2 more
2007Basic Research in Cardiology229 citations
Semantic Scholar
Metformin protects the ischemic heart by the Akt-mediated inhibition of mitochondrial permeability transition pore opening
G. Bhamra, D. Hausenloy, S. Davidson, R. D. Carr +4 more
2008Basic Research in Cardiology213 citations
Semantic Scholar
Leptin, the obesity‐associated hormone, exhibits direct cardioprotective effects
Clare E. Smith, M. Mocanu, S. Davidson, Abigail M. Wynne +2 more
2006British Journal of Pharmacology159 citations Open access
Semantic Scholar
Leptin-induced cardioprotection involves JAK/STAT signaling that may be linked to the mitochondrial permeability transition pore.
Christopher C. T. Smith, R. Dixon, Abigail M. Wynne, L. Theodorou +5 more
2010American Journal of Physiology. Heart and Circulatory Physiology112 citations Open access
Semantic Scholar
Dipeptidyl peptidase-4 inhibitors and GLP-1 reduce myocardial infarct size in a glucose-dependent manner
D. Hausenloy, H. Whittington, Abigail M. Wynne, S. Begum +4 more
2013Cardiovascular Diabetology90 citations Open access
Semantic Scholar
Preconditioning the diabetic human myocardium
V. Sivaraman, D. Hausenloy, Abigail M. Wynne, D. Yellon
2009Journal of Cellular and Molecular Medicine88 citations Open access
Semantic Scholar
Ischemic preconditioning targets the reperfusion phase
D. Hausenloy, Abigail M. Wynne, D. Yellon
2007Basic Research in Cardiology87 citations
Semantic Scholar
Pioglitazone Mimics Preconditioning in the Isolated Perfused Rat Heart: A Role for the Prosurvival Kinases PI3K and P42/44MAPK
Abigail M. Wynne, M. Mocanu, D. Yellon
2005Journal of Cardiovascular Pharmacology64 citations Open access
Semantic Scholar
Temporal Changes in Myocardial Salvage Kinases During Reperfusion Following Ischemia: Studies Involving the Cardioprotective Adipocytokine Apelin
Christopher C. T. Smith, M. M. Mocanu, J. Bowen, Abigail M. Wynne +4 more
2007Cardiovascular Drugs and Therapy60 citations
Semantic Scholar
Glimepiride Treatment Facilitates Ischemic Preconditioning in the Diabetic Heart
D. Hausenloy, Abigail M. Wynne, M. Mocanu, D. Yellon
2013Journal of Cardiovascular Pharmacology and Therapeutics35 citations Open access
Semantic Scholar
The Cardioprotective Actions of Leptin Are Lost in the Zucker Obese (fa/fa) Rat
R. Dixon, S. Davidson, Abigail M. Wynne, D. Yellon +1 more
2009Journal of Cardiovascular Pharmacology24 citations
Semantic Scholar
Failure of the Adipocytokine, Resistin, to Protect the Heart From Ischemia-Reperfusion Injury
Christopher C. T. Smith, Shiang Y. Lim, Abigail M. Wynne, V. Sivaraman +4 more
2011Journal of Cardiovascular Pharmacology and Therapeutics15 citations Open access
Semantic Scholar
Apelin exhibits cardioprotection against ischaemia reperfusion injury
James C. Simpkin, D. Yellon, S. Davidson, S. Lim +2 more
20079 citations
Semantic Scholar
Dipeptidyl peptidase IV inhibitors limit myocardial infarct size in a glucose-sensitive manner
D. Hausenloy, Abigail M. Wynne, Louise Theodorou, M. Mocanu +1 more
20105 citations
Semantic Scholar
Ischaemic Preconditioning and Postconditioning do not Affect Adenosine A1 and A2A Receptor Sensitivity
N. Riksen, Abigail M. Wynne, D. Yellon, D. Hausenloy
2009Cardiovascular Drugs and Therapy4 citations Open access
Semantic Scholar
Glimepiride reduces the threshold for ischemic preconditioning in the diabetic heart
Abigail M. Wynne, D. Hausenloy, M. Mocanu, D. Yellon
20074 citations
Semantic Scholar
The metabolic syndrome raises the threshold for cardioprotection
D. Hausenloy, Abigail M. Wynne, M. Mocanu, D. Yellon
20073 citations
Semantic Scholar
Apelin, the potentially therapeutic adipocytokine, protects against myocardial ischemia-reperfusion injury
James C. Simpkin, Shiang Y. Lim, S. Davidson, Abigail M. Wynne +2 more
20072 citations
Semantic Scholar
Over-expression of the cardioprotective kinase Akt modulates mitochondrial morphology
D. Hausenloy, S. Davidson, Abigail M. Wynne, S. Cipolat +2 more
20080 citations
Semantic Scholar
The adipocytokine, resistin, is not cardioprotective despite activating components of the risk pathway
Shiang Y. Lim, Christopher C. T. Smith, Abigail M. Wynne, V. Sivaraman +4 more
20080 citations
Semantic Scholar
Reperfusion signaling in preconditioned hearts: Role for Pkc, The Mkatp channel, oxidative stress and transient acidosis
Abigail M. Wynne, D. Hausenloy
20070 citations
Semantic Scholar
Leptin, the obesity-related adipocytokine, protects the myocardium against ischaemia-reperfusion injury
Christopher C. T. Smith, M. Mocanu, S. M. Davidson, Abigail M. Wynne +2 more
20060 citations
Semantic Scholar
Does the mitochondrial permeability transition pore have a role in preconditioning?-letter to editor
D. Hausenloy, Abigail M. Wynne, M. Duchen, D. Yellon
20040 citations
Semantic Scholar
Does the mitochondrial permeability transition have a role in preconditioning? Response
D. Hausenloy, Abigail M. Wynne, D. Yellon, M. Duchen
20040 citations
Semantic Scholar
320 Preconditioning protects via dual modulation of the mitochondrial permeability transition pore
D. Hausenloy, Siva Mani-Babu, Abigail M. Wynne, M. Duchen +1 more
20030 citations
Semantic Scholar

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D. Yellon×22
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D. Yellon — researcher profile on SciRah
D. Hausenloy×18
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D. Hausenloy — researcher profile on SciRah
S. Davidson×10
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M. Mocanu×10
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Christopher C. T. Smith

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Christopher C. T. Smith — researcher profile on SciRah

James C. Simpkin×6

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M. Duchen — researcher profile on SciRah

Shiang Y. Lim×4

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R. Dixon — researcher profile on SciRah

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N. Riksen — researcher profile on SciRah