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L. Frawley · SciRah

Researcher profile · Semantic Scholar

L. Frawley

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L. Frawley — researcher profile on SciRah

h-index: 35
Works: 117
Citations: 4,011

Most-cited papers

Mammosomatotropes: presence and functions in normal and neoplastic pituitary tissue.
L. Frawley, F. R. Boockfor
1991Endocrine reviews203 citations
Semantic Scholar
Identification by plaque assays of a pituitary cell type that secretes both growth hormone and prolactin.
L. Frawley, F. Boockfor, J. Hoeffler
1985Endocrinology181 citations
Semantic Scholar
Ontogeny of prolactin cells in neonatal rats: initial prolactin secretors also release growth hormone.
J. Hoeffler, F. Boockfor, L. Frawley
1985Endocrinology175 citations
Semantic Scholar
Development of a destabilized firefly luciferase enzyme for measurement of gene expression.
Gilles M. Leclerc, Fredric R. Boockfor, W. J. Faught, L. Frawley
2000BioTechniques148 citations Open access
Semantic Scholar
Analysis by plaque assays of GH and prolactin release from individual cells in cultures of male pituitaries. Evidence for functional heterogeneity within rat mammotrope and somatotrope populations.
F. Boockfor, J. Hoeffler, L. Frawley
1986Neuroendocrinology111 citations
Semantic Scholar
Functional variations among prolactin cells from different pituitary regions.
Fredric R. Boockfor, L. Frawley
1987Endocrinology94 citations
Semantic Scholar
Is the mammosomatotrope a transitional cell for the functional interconversion of growth hormone- and prolactin-secreting cells? Suggestive evidence from virgin, gestating, and lactating rats.
Tom E. Porter, J. Hill, C. Wiles, L. Frawley
1990Endocrinology77 citations
Semantic Scholar
Multi-responsiveness of single anterior pituitary cells to hypothalamic-releasing hormones: a cellular basis for paradoxical secretion.
C. Villalobos, L. Núñez, L. Frawley, J. García-Sancho +1 more
1997Proceedings of the National Academy of Sciences of the United States of America76 citations Open access
Semantic Scholar
Estradiol induces a shift in cultured cells that release prolactin or growth hormone.
F. Boockfor, J. Hoeffler, L. Frawley
1986American Journal of Physiology76 citations
Semantic Scholar
Evidence for bidirectional interconversion of mammotropes and somatotropes: rapid reversion of acidophilic cell types to pregestational proportions after weaning.
Tom E. Porter, C. Wiles, L. Frawley
1991Endocrinology74 citations
Semantic Scholar
Cultures of GH3 cells are functionally heterogeneous: thyrotropin-releasing hormone, estradiol and cortisol cause reciprocal shifts in the proportions of growth hormone and prolactin secretors.
F. R. Boockfor, J. Hoeffler, L. Frawley
1985Endocrinology68 citations
Semantic Scholar
Steroids can modulate transdifferentiation of prolactin and growth hormone cells in bovine pituitary cultures.
R. Kineman, W. J. Faught, L. Frawley
1992Endocrinology60 citations
Semantic Scholar
Synchronized exocytotic bursts from gonadotropin-releasing hormone-expressing cells: dual control by intrinsic cellular pulsatility and gap junctional communication.
R. Vázquez-Martínez, S. Shorte, Fredric R. Boockfor, L. Frawley
2001Endocrinology59 citations Open access
Semantic Scholar
Dynamic monitoring and quantification of gene expression in single, living cells: a molecular basis for secretory cell heterogeneity.
Justo P. Castaño, R. Kineman, L. Frawley
1996Molecular Endocrinology56 citations Open access
Semantic Scholar
Growth Hormone (GH)-Releasing Factor Differentially Activates Cyclic Adenosine 3',5'-Monophosphate- and Inositol Phosphate-Dependent Pathways to Stimulate GH Release in Two Porcine Somatotrope Subpopulations.
J. Ramírez, J. Castaño, Rafael Torronteras, A. Martínez-Fuentes +3 more
1999Endocrinology47 citations
Semantic Scholar
Rapid augmentation of prolactin cell number and secretory capacity by an estrogen-induced factor released from the neurointermediate lobe.
E. Ellerkmann, G. M. Nagy, L. Frawley
1991Endocrinology45 citations
Semantic Scholar
Alpha-melanocyte-stimulating hormone is a mammotrophic factor released by neurointermediate lobe cells after estrogen treatment.
E. Ellerkmann, G. Nagy, L. Frawley
1992Endocrinology44 citations Open access
Semantic Scholar
Functional maturation of somatotropes in fetal rat pituitaries: analysis by reverse hemolytic plaque assay.
L. Frawley, J. Hoeffler, F. Boockfor
1985Endocrinology44 citations
Semantic Scholar
Suckling unmasks the stimulatory effect of dopamine on prolactin release: possible role for alpha-melanocyte-stimulating hormone as a mammotrope responsiveness factor.
J. Hill, G. M. Nagy, L. Frawley
1991Endocrinology42 citations
Semantic Scholar
Capacity of individual somatotropes to release growth hormone varies according to sex: analysis by reverse hemolytic plaque assay.
J. Hoeffler, L. Frawley
1986Endocrinology42 citations
Semantic Scholar
Episodic gonadotropin-releasing hormone gene expression revealed by dynamic monitoring of luciferase reporter activity in single, living neurons.
L. Núñez, W. J. Faught, L. Frawley
1998Proceedings of the National Academy of Sciences of the United States of America41 citations Open access
Semantic Scholar
Mammosomatotropes: current status and possible functions.
L. Frawley
1989Trends in endocrinology and metabolism40 citations
Semantic Scholar
Dynamic changes in spontaneous intracellular free calcium oscillations and their relationship to prolactin gene expression in single, primary mammotropes.
Carlos Villalobos, W. J. Faught, L. Frawley
1998Molecular Endocrinology39 citations Open access
Semantic Scholar
Evidence that stimulatory dopamine receptors may be involved in the regulation of prolactin secretion.
Tom E. Porter, D. Grandy, J. Bunzow, C. Wiles +2 more
1994Endocrinology36 citations
Semantic Scholar
Mammosomatotropes are abundant in bovine pituitaries: influence of gonadal status.
R. Kineman, W. J. Faught, L. Frawley
1991Endocrinology36 citations
Semantic Scholar
Dual expression of p80 type I and p68 type II interleukin-I receptors on anterior pituitary cells synthesizing growth hormone.
Richard A. French, J. Zachary, R. Dantzer, L. Frawley +3 more
1996Endocrinology35 citations Open access
Semantic Scholar
Suckling increases the proportions of mammotropes responsive to various prolactin-releasing stimuli.
G. M. Nagy, L. Frawley
1990Endocrinology35 citations
Semantic Scholar
Hypothalamic factors differentially affect the proportions of cells that secrete growth hormone or prolactin.
J. Hoeffler, L. Frawley
1987Endocrinology35 citations
Semantic Scholar
Ovine prolactin (PRL) and dopamine preferentially inhibit PRL release from the same subpopulation of rat mammotropes.
L. Frawley, C. L. Clark
1986Endocrinology34 citations
Semantic Scholar
Extracellular ATP as an autocrine/paracrine regulator of prolactin release.
L. Núñez, C. Villalobos, L. Frawley
1997American Journal of Physiology32 citations
Semantic Scholar
Real time measurement of gene expression in living endocrine cells.
L. Frawley, W. J. Faught, J. Nicholson, B. Moomaw
1994Endocrinology32 citations
Semantic Scholar
Fluctuations in the proportions of growth hormone- and prolactin-secreting cells during the bovine estrous cycle.
R. Kineman, D. Henricks, W. J. Faught, L. Frawley
1991Endocrinology32 citations
Semantic Scholar
Octylphenol (OP), an environmental estrogen, stimulates prolactin (PRL) gene expression.
E. J. Abraham, L. Frawley
1997Life Science31 citations
Semantic Scholar
The ontogenic and functional relationships between growth hormone- and prolactin-releasing cells during the development of the bovine pituitary.
R. Kineman, W. J. Faught, L. Frawley
1992Journal of Endocrinology31 citations
Semantic Scholar
The relationship between pulsatile secretion and calcium dynamics in single, living gonadotropin-releasing hormone neurons.
L. Núñez, C. Villalobos, F. Boockfor, L. Frawley
2000Endocrinology30 citations Open access
Semantic Scholar
Pulsatile exocytosis is functionally associated with GnRH gene expression in immortalized GnRH-expressing cells.
R. Vázquez-Martínez, S. Shorte, W. J. Faught, David C. Leaumont +2 more
2001Endocrinology29 citations
Semantic Scholar
Phytoestrogens have agonistic and combinatorial effects on estrogen-responsive gene expression in MCF-7 human breast cancer cells
S. Willard, L. Frawley
1998Endocrine29 citations
Semantic Scholar
The suckling stimulus increases the responsiveness of mammotropes located exclusively within the central region of the adenohypophysis.
G. M. Nagy, Fredric R. Boockfor, L. Frawley
1991Endocrinology29 citations Open access
Semantic Scholar
Bovine pituitary cells exhibit a unique form of somatotrope secretory heterogeneity.
R. Kineman, W. J. Faught, L. Frawley
1990Endocrinology29 citations
Semantic Scholar
PRL gene expression in individual living mammotropes displays distinct functional pulses that oscillate in a noncircadian temporal pattern.
S. Shorte, Gilles M. Leclerc, R. Vázquez-Martínez, David C. Leaumont +3 more
2002Endocrinology28 citations Open access
Semantic Scholar
Stimulation of lactotrope differentiation in vitro by fibroblast growth factor.
Tom E. Porter, C. Wiles, L. Frawley
1994Endocrinology26 citations
Semantic Scholar
Analysis of relaxin release from cultured porcine luteal cells by reverse hemolytic plaque assay: influence of gestational age and prostaglandin F2 alpha.
Michael J. Taylor, C. L. Clark, L. Frawley
1987Endocrinology26 citations
Semantic Scholar
Does alpha-melanocyte-stimulating hormone from the pars intermedia regulate suckling-induced prolactin release? Supportive evidence from morphological and functional studies.
J. Hill, E. Lacy, G. Nagy, T. Görcs +1 more
1993Endocrinology25 citations
Semantic Scholar
Relative importance of newly synthesized and stored hormone to basal secretion by growth hormone and prolactin cells.
Thomas T. Chen, R. Kineman, J. Betts, J. Hill +1 more
1989Endocrinology25 citations
Semantic Scholar
Dynamics of stimulus-expression coupling as revealed by monitoring of prolactin promoter-driven reporter activity in individual, living mammotropes.
Carlos Villalobos, W. J. Faught, L. Frawley
1999Molecular Endocrinology24 citations Open access
Semantic Scholar
Dynamic fluctuations in the secretory activity of individual lactotropes as demonstrated by a modified sequential plaque assay.
Justo P. Castaño, R. Kineman, L. Frawley
1994Endocrinology23 citations
Semantic Scholar
Normal differentiation of prolactin cells in neonatal rats requires a maternal signal specific to early lactation.
Tom E. Porter, Lara E. Chapman, F. V. Van Dolah, L. Frawley
1991Endocrinology22 citations
Semantic Scholar
Ontogeny of prolactin secretion in the neonatal rat is regulated posttranscriptionally.
L. Frawley, H. A. Miller
1989Endocrinology22 citations
Semantic Scholar
Lactotrope differentiation in rats is modulated by a milk-borne signal transferred to the neonatal circulation.
Tom E. Porter, C. Wiles, L. Frawley
1993Endocrinology20 citations
Semantic Scholar
A cellular basis for growth hormone deficiency in the dwarf rat: analysis of growth hormone and prolactin release by reverse hemolytic plaque assay.
R. Kineman, Thomas T. Chen, L. Frawley
1989Endocrinology20 citations
Semantic Scholar

Frequent co-authors

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W. J. Faught×12
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W. J. Faught — researcher profile on SciRah
R. Kineman×9
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R. Kineman — researcher profile on SciRah
J. Hoeffler×8
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J. Hoeffler — researcher profile on SciRah
F. Boockfor×6
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F. Boockfor — researcher profile on SciRah

Fredric R. Boockfor

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C. Wiles — researcher profile on SciRah

Tom E. Porter×5

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Tom E. Porter — researcher profile on SciRah

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J. Hill — researcher profile on SciRah

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L. Núñez — researcher profile on SciRah

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G. M. Nagy — researcher profile on SciRah

C. Villalobos×3

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C. Villalobos — researcher profile on SciRah

R. Vázquez-Martínez×3

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R. Vázquez-Martínez — researcher profile on SciRah