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S. Malherbe · SciRah

Researcher profile · Semantic Scholar

S. Malherbe

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S. Malherbe — researcher profile on SciRah

h-index: 29
Works: 121
Citations: 3,184

Most-cited papers

A multi-cohort study of the immune factors associated with M. tuberculosis infection outcomes
R. Chowdhury, Francesco Vallania, Qian-Ting Yang, C. Angel +14 more
2018Nature223 citations Open access
Semantic Scholar
RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response
A. Penn-Nicholson, S. K. Mbandi, E. Thompson, S. Mendelsohn +29 more
2020Scientific Reports142 citations Open access
Semantic Scholar
Biomarker-guided tuberculosis preventive therapy (CORTIS): a randomised controlled trial
T. Scriba, A. Fiore-Gartland, A. Penn-Nicholson, H. Mulenga +155 more
2021Lancet. Infectious Diseases (Print)109 citations Open access
Semantic Scholar
Diagnostic Accuracy of the Cepheid 3-gene Host Response Fingerstick Blood Test in a Prospective, Multi-site Study: Interim Results
J. Sutherland, G. D. van der Spuy, Awa Gindeh, T. T. Nguyen +16 more
2021Clinical Infectious Diseases90 citations Open access
Semantic Scholar
International consensus classification of early tuberculosis states to guide research for improved care and prevention: A Delphi exercise
A. Coussens, S. M. Zaidi, Brian W. Allwood, Puneet K. Dewan +52 more
2024The Lancet Respiratory Medicine81 citations Open access
Semantic Scholar
Impact of Intermediate Hyperglycemia and Diabetes on Immune Dysfunction in Tuberculosis
C. Eckold, Vinod Kumar, J. Weiner, B. Alisjahbana +126 more
2020Clinical Infectious Diseases62 citations Open access
Semantic Scholar
Higher SARS-CoV-2 seroprevalence in workers with lower socioeconomic status in Cape Town, South Africa
J. Shaw, M. Meiring, Tracy Cummins, N. Chegou +16 more
2020PLoS ONE53 citations Open access
Semantic Scholar
Validation of a host blood transcriptomic biomarker for pulmonary tuberculosis in people living with HIV: a prospective diagnostic and prognostic accuracy study
S. Mendelsohn, A. Fiore-Gartland, A. Penn-Nicholson, H. Mulenga +231 more
2021Lancet Global Health50 citations Open access
Semantic Scholar
Diabetes mellitus among pulmonary tuberculosis patients from four TB-endemic countries: the TANDEM study.
C. Ugarte-Gil, B. Alisjahbana, K. Ronacher, A. Riza +19 more
2019Clinical Infectious Diseases49 citations Open access
Semantic Scholar
Diabetes Mellitus Among Pulmonary Tuberculosis Patients From 4 Tuberculosis-endemic Countries: The TANDEM Study
F. Pearson, C. Ugarte-Gil, B. Alisjahbana, K. Ronacher +19 more
202045 citations
Semantic Scholar
Quantitative 18F-FDG PET-CT scan characteristics correlate with tuberculosis treatment response
S. Malherbe, Ray Y. Chen, P. Dupont, I. Kant +21 more
2020EJNMMI Research45 citations Open access
Semantic Scholar
Fourteen-day PET/CT imaging to monitor drug combination activity in treated individuals with tuberculosis
Ying-Da L. Xie, V. D. de Jager, Ray Y. Chen, Lori E. Dodd +20 more
2021Science Translational Medicine44 citations Open access
Semantic Scholar
Investigating Non-sterilizing Cure in TB Patients at the End of Successful Anti-TB Therapy
Caroline G. G. Beltran, Tiaan Heunis, J. Gallant, R. Venter +7 more
2020Frontiers in Cellular and Infection Microbiology35 citations Open access
Semantic Scholar
Radiological and functional evidence of the bronchial spread of tuberculosis: an observational analysis
Ray Y. Chen, Xiang Yu, Bronwyn Smith, Xin Liu +19 more
2021The Lancet Microbe31 citations Open access
Semantic Scholar
Longitudinal Dynamics of a Blood Transcriptomic Signature of Tuberculosis
H. Mulenga, M. Musvosvi, S. Mendelsohn, A. Penn-Nicholson +29 more
2021American Journal of Respiratory and Critical Care Medicine31 citations Open access
Semantic Scholar
Expression and production of the SERPING1-encoded endogenous complement regulator C1-inhibitor in multiple cohorts of tuberculosis patients.
R. Lubbers, J. Sutherland, D. Goletti, R. D. de Paus +14 more
2020Molecular Immunology31 citations Open access
Semantic Scholar
Validation and Optimization of Host Immunological Bio-Signatures for a Point-of-Care Test for TB Disease
H. Mutavhatsindi, G. D. van der Spuy, S. Malherbe, J. Sutherland +14 more
2021Frontiers in Immunology27 citations Open access
Semantic Scholar
Accuracy of diabetes screening methods used for people with tuberculosis, Indonesia, Peru, Romania, South Africa
D. Grint, Bachti Alisjhabana, C. Ugarte-Gil, A. Riza +15 more
2018Bulletin of the World Health Organization27 citations Open access
Semantic Scholar
Prospective evaluation of host biomarkers other than interferon gamma in QuantiFERON Plus supernatants as candidates for the diagnosis of tuberculosis in symptomatic individuals
Portia M. Manngo, A. Gutschmidt, Candice Snyders, H. Mutavhatsindi +10 more
2019Journal of Infection26 citations Open access
Semantic Scholar
Screening for asymptomatic tuberculosis among adults with household exposure to pulmonary tuberculosis: a prospective observational cohort study
S. Mendelsohn, H. Mulenga, M. Tameris, T. Moloantoa +15 more
2025Lancet Global Health25 citations
Semantic Scholar
Disease characteristics and treatment of patients with diabetes mellitus attending government health services in Indonesia, Peru, Romania and South Africa
N. Soetedjo, S. McAllister, C. Ugarte-Gil, A. Firănescu +20 more
2018Tropical medicine & international health24 citations Open access
Semantic Scholar
Immune Profiling Enables Stratification of Patients With Active Tuberculosis Disease or Mycobacterium tuberculosis Infection
D. Duffy, E. Nemes, A. Llibre, V. Rouilly +16 more
2020Clinical Infectious Diseases23 citations Open access
Semantic Scholar
A semi-automatic technique to quantify complex tuberculous lung lesions on 18F-fluorodeoxyglucose positron emission tomography/computerised tomography images
S. Malherbe, P. Dupont, I. Kant, Petri Ahlers +14 more
2018EJNMMI Research21 citations Open access
Semantic Scholar
Mycobacterium tuberculosis resisters despite HIV exhibit activated T cells and macrophages in their pulmonary alveoli
M. Dallmann-Sauer, V. Fava, S. Malherbe, Candice Macdonald +11 more
2025Journal of Clinical Investigation20 citations Open access
Semantic Scholar
Combining host-derived biomarkers with patient characteristics improves signature performance in predicting tuberculosis treatment outcomes
Dhanasekaran Sivakumaran, S. Jenum, M. Vaz, S. Selvam +6 more
2020Communications Biology20 citations Open access
Semantic Scholar
Point of care HbA1c level for diabetes mellitus management and its accuracy among tuberculosis patients: a study in four countries.
P. Huangfu, Y. Laurence, B. Alisjahbana, C. Ugarte-Gil +18 more
2019The International Journal of Tuberculosis and Lung Disease20 citations
Semantic Scholar
Establishment of a Patient-Derived, Magnetic Levitation-Based, Three-Dimensional Spheroid Granuloma Model for Human Tuberculosis
Leigh A. Kotze, Caroline G. G. Beltran, Dirk M. Lang, A. Loxton +10 more
2021Msphere19 citations Open access
Semantic Scholar
High resolution imaging and five-year tuberculosis contact outcomes
H. Esmail, A. Coussens, Friedrich Thienemann, B. Sossen +32 more
2023medRxiv18 citations Open access
Semantic Scholar
Host urine immunological biomarkers as potential candidates for the diagnosis of tuberculosis.
O. Eribo, Monkoe Leqheka, S. Malherbe, Shirley McAnda +4 more
2020International Journal of Infectious Diseases18 citations Open access
Semantic Scholar
Blood transcriptomic signatures for symptomatic tuberculosis in an African multicohort study
V. Muwanga, S. Mendelsohn, Vinzeigh Leukes, K. Stanley +12 more
2024European Respiratory Journal17 citations Open access
Semantic Scholar
Neutrophil degranulation, NETosis and platelet degranulation pathway genes are co-induced in whole blood up to six months before tuberculosis diagnosis
S. Meier, J. Seddon, E. Maasdorp, L. Kleynhans +15 more
2022bioRxiv16 citations Open access
Semantic Scholar
Transcriptional profiles predict treatment outcome in patients with tuberculosis and diabetes at diagnosis and at two weeks after initiation of anti-tuberculosis treatment
Cassandra L. R. van Doorn, C. Eckold, K. Ronacher, R. Ruslami +19 more
2022medRxiv16 citations Open access
Semantic Scholar
Point-of-care C-reactive protein and Xpert MTB/RIF Ultra for tuberculosis screening and diagnosis in unselected antiretroviral therapy initiators: a prospective, cross-sectional, diagnostic accuracy study
B. Reeve, G. Ndlangalavu, Hridesh Mishra, Zaida Palmer +15 more
2024Lancet Global Health15 citations Open access
Semantic Scholar
Diagnostic Accuracy of Chest X-ray Computer-Aided Detection Software for Detection of Prevalent and Incident Tuberculosis in Household Contacts
Liana Macpherson, S. Kik, M. Quartagno, F. Lakay +35 more
2024Clinical Infectious Diseases14 citations Open access
Semantic Scholar
Understanding the biology, morbidity and social contexts of adolescent tuberculosis: a prospective observational cohort study protocol (Teen TB)
J. Swanepoel, K. Zimri, M. M. van der Zalm, G. Hoddinott +20 more
2022BMJ Open14 citations Open access
Semantic Scholar
Screening diabetes mellitus patients for pulmonary tuberculosis: a multisite study in Indonesia, Peru, Romania and South Africa.
B. Alisjahbana, S. McAllister, C. Ugarte-Gil, N. Panduru +16 more
2020Transactions of the Royal Society of Tropical Medicine and Hygiene14 citations Open access
Semantic Scholar
Field evaluation of a point-of-care triage test for active tuberculosis (TriageTB)
Tracy Richardson, Bronwyn Smith, S. Malherbe, J. Shaw +47 more
2023BMC Infectious Diseases13 citations Open access
Semantic Scholar
Targeting of myeloid-derived suppressor cells by all-trans retinoic acid as host-directed therapy for human tuberculosis
Vinzeigh Leukes, A. Dorhoi, S. Malherbe, E. Maasdorp +4 more
2021Cellular Immunology13 citations Open access
Semantic Scholar
The Peripheral Blood Transcriptome Is Correlated With PET Measures of Lung Inflammation During Successful Tuberculosis Treatment
Trust Odia, S. Malherbe, S. Meier, E. Maasdorp +11 more
2021Frontiers in Immunology12 citations Open access
Semantic Scholar
Identification of novel salivary candidate protein biomarkers for tuberculosis diagnosis: A preliminary biomarker discovery study.
H. Mutavhatsindi, B. Calder, Shirley McAnda, S. Malherbe +4 more
2020Tuberculosis12 citations Open access
Semantic Scholar
Concurrent evaluation of cytokines improves the accuracy of antibodies against Mycobacterium tuberculosis antigens in the diagnosis of active tuberculosis.
Ruschca Jacobs, D. Awoniyi, Ralf Baumann, K. Stanley +6 more
2022Tuberculosis11 citations Open access
Semantic Scholar
Performance of 2 Finger-Stick Blood Tests to Triage Adults With Symptoms of Pulmonary Tuberculosis: A Prospective Multisite Diagnostic Accuracy Study
J. Sutherland, G. D. van der Spuy, Jane A. Shaw, Tracy Richardson +25 more
2025Clinical Infectious Diseases10 citations Open access
Semantic Scholar
Performance and immune characteristics of bronchoalveolar lavage by research bronchoscopy in pulmonary tuberculosis and other lung diseases in the Western Cape, South Africa
Carly Young, Petri Ahlers, Andriette M. Hiemstra, A. Loxton +5 more
2019Translational Medicine Communications10 citations Open access
Semantic Scholar
PET/CT guided tuberculosis treatment shortening: a randomized trial
S. Malherbe, Ray Y. Chen, Xiang Yu, Bronwyn Smith +51 more
2024medRxiv9 citations Open access
Semantic Scholar
RISK6, a universal 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response
A. Penn-Nicholson, S. K. Mbandi, E. Thompson, S. Mendelsohn +25 more
20199 citations Open access
Semantic Scholar
Prospective Validation of a Host Blood Transcriptomic Biomarker for Pulmonary Tuberculosis in People Living with HIV: A Diagnostic and Prognostic Accuracy Study
S. Mendelsohn, A. Fiore-Gartland, A. Penn-Nicholson, H. Mulenga +25 more
20218 citations Open access
Semantic Scholar
PET–CT benchmarked detection and 5-year progression of asymptomatic tuberculosis: a longitudinal, prospective cohort study
H. Esmail, Friedrich Thienemann, B. Sossen, S. Mukasa +34 more
2026The Lancet Respiratory Medicine7 citations Open access
Semantic Scholar
Immunologic and vascular biomarkers of mortality in critical COVID-19 in a South African cohort
J. Shaw, M. Meiring, Candice Snyders, F. Everson +19 more
2023Frontiers in Immunology7 citations Open access
Semantic Scholar
Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity
C. Eckold, Cassandra L. R. van Doorn, R. Ruslami, K. Ronacher +21 more
2022medRxiv7 citations Open access
Semantic Scholar
The potential of imaging tools as correlates of infection and disease for new TB vaccine development.
S. Malherbe, L. Kleynhans, G. Walzl
2018Seminars in Immunology7 citations
Semantic Scholar

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