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M. Spehlmann · SciRah

Researcher profile · Semantic Scholar

M. Spehlmann

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M. Spehlmann — researcher profile on SciRah

h-index: 21
Works: 66
Citations: 3,395

Most-cited papers

Natalizumab for the treatment of active Crohn's disease: results of the ENCORE Trial.
S. Targan, B. Feagan, R. Fedorak, B. Lashner +10 more
2007Gastroenterology638 citations
Semantic Scholar
Twin study indicates loss of interaction between microbiota and mucosa of patients with ulcerative colitis.
P. Lepage, R. Häsler, M. Spehlmann, A. Rehman +7 more
2011Gastroenterology585 citations Open access
Semantic Scholar
Heart failure is associated with depletion of core intestinal microbiota
M. Luedde, Thorben Winkler, Femke-Anouska Heinsen, M. Rühlemann +6 more
2017ESC Heart Failure289 citations Open access
Semantic Scholar
Epidemiology of inflammatory bowel disease in a German twin cohort: Results of a nationwide study
M. Spehlmann, A. Begun, J. Burghardt, P. Lepage +2 more
2008Inflammatory Bowel Diseases203 citations Open access
Semantic Scholar
Absence of RNase H2 triggers generation of immunogenic micronuclei removed by autophagy
Kareen Bartsch, Katharina Knittler, Christopher Borowski, S. Rudnik +7 more
2017Human Molecular Genetics189 citations Open access
Semantic Scholar
IL-6-Dependent Mucosal Protection Prevents Establishment of a Microbial Niche for Attaching/Effacing Lesion-Forming Enteric Bacterial Pathogens1
Sara M. Dann, M. Spehlmann, D. Hammond, M. Iimura +4 more
2008Journal of Immunology185 citations Open access
Semantic Scholar
Constitutive intestinal NF-κB does not trigger destructive inflammation unless accompanied by MAPK activation
Mónica Gumá, D. Stepniak, Helena Shaked, M. Spehlmann +6 more
2011Journal of Experimental Medicine167 citations Open access
Semantic Scholar
Nuclear factor-kappa B in intestinal protection and destruction
M. Spehlmann, L. Eckmann
2009Current Opinion in Gastroenterology158 citations Open access
Semantic Scholar
Certolizumab pegol in patients with moderate to severe Crohn's disease and secondary failure to infliximab.
W. Sandborn, M. Abreu, G. D'Haens, J. Colombel +8 more
2010Clinical Gastroenterology and Hepatology157 citations
Semantic Scholar
A functional methylome map of ulcerative colitis
R. Häsler, Zhe Feng, L. Bäckdahl, M. Spehlmann +9 more
2012Genome Research140 citations Open access
Semantic Scholar
CXCR2-Dependent Mucosal Neutrophil Influx Protects against Colitis-Associated Diarrhea Caused by an Attaching/Effacing Lesion-Forming Bacterial Pathogen
M. Spehlmann, Sara M. Dann, P. Hruz, Elaine M. Hanson +2 more
2009Journal of Immunology101 citations Open access
Semantic Scholar
Interferon-β-1a for the Treatment of Steroid-Refractory Ulcerative Colitis: A Randomized, Double-Blind, Placebo-Controlled Trial
E. Musch, T. Andus, W. Kruis, A. Raedler +7 more
200558 citations Open access
Semantic Scholar
Activin and TGFβ use diverging mitogenic signaling in advanced colon cancer
J. Bauer, Ö. Özden, N. Akagi, Timothy J. Carroll +6 more
2015Molecular Cancer55 citations Open access
Semantic Scholar
Whole genome and exome sequencing of monozygotic twins discordant for Crohn’s disease
B. Petersen, M. Spehlmann, A. Raedler, Björn Stade +5 more
2014BMC Genomics43 citations Open access
Semantic Scholar
Risk factors in German twins with inflammatory bowel disease: results of a questionnaire-based survey.
M. Spehlmann, A. Begun, Ekaterini Saroglou, F. Hinrichs +3 more
2012Journal of Crohn's & Colitis39 citations
Semantic Scholar
Trp53 deficiency protects against acute intestinal inflammation
M. Spehlmann, C. Manthey, Sara M. Dann, Elaine M. Hanson +10 more
2013Journal of Immunology36 citations Open access
Semantic Scholar
Radial access protects from contrast media induced nephropathy after cardiac catheterization procedures
T. Feldkamp, Maya Luedemann, M. Spehlmann, S. Freitag-Wolf +8 more
2018Clinical Research in Cardiology32 citations
Semantic Scholar
Combined alpha-methylacyl coenzyme A racemase/p53 analysis to identify dysplasia in inflammatory bowel disease.
A. Marx, Timo Wandrey, P. Simon, Agatha Wewer +17 more
2009Human Pathology31 citations
Semantic Scholar
Heart Failure Severity Closely Correlates with Intestinal Dysbiosis and Subsequent Metabolomic Alterations
M. Spehlmann, A. Rangrez, D. Dhotre, Nesrin Schmiedel +7 more
2022Biomedicines29 citations Open access
Semantic Scholar
Interferon-beta-1a for the treatment of steroid-refractory ulcerative colitis: a randomized, double-blind, placebo-controlled trial.
E. Musch, T. Andus, W. Kruis, A. Raedler +7 more
2005Clinical Gastroenterology and Hepatology27 citations
Semantic Scholar
Cardio-toxicity of checkpoint inhibitors.
O. Müller, M. Spehlmann, N. Frey
2018Journal of Thoracic Disease24 citations Open access
Semantic Scholar
Identification of Disease-associated Traits and Clonotypes in the T Cell Receptor Repertoire of Monozygotic Twins Affected by Inflammatory Bowel Diseases
E. Rosati, M. Pogorelyy, C. Dowds, F. T. Moller +8 more
2019Journal of Crohn's & Colitis21 citations Open access
Semantic Scholar
Serum Levels of Kisspeptin Are Elevated in Patients with Pancreatic Cancer
S. Loosen, M. Luedde, G. Lurje, M. Spehlmann +8 more
2019Disease Markers19 citations Open access
Semantic Scholar
Genetic control of global gene expression levels in the intestinal mucosa: a human twin study.
R. Häsler, A. Begun, S. Freitag-Wolf, M. Kerick +7 more
2009Physiological Genomics19 citations
Semantic Scholar
Elevated Omentin Serum Levels Predict Long-Term Survival in Critically Ill Patients
M. Luedde, Fabian Benz, Jennifer Niedeggen, M. Vucur +10 more
2016Disease Markers18 citations Open access
Semantic Scholar
miR-155 Predicts Long-Term Mortality in Critically Ill Patients Younger than 65 Years
F. Tacke, M. Spehlmann, M. Vucur, Fabian Benz +10 more
2019Mediators of Inflammation14 citations Open access
Semantic Scholar
Coordinate Down-regulation of Adenylyl Cyclase Isoforms and the Stimulatory G Protein (Gs) in Intestinal Epithelial Cell Differentiation*
L. Choi, G. Jenikova, Elaine M. Hanson, M. Spehlmann +6 more
2010Journal of Biological Chemistry13 citations Open access
Semantic Scholar
Serum Levels of miR-143 Predict Survival in Critically Ill Patients
C. Roderburg, A. Koch, Fabian Benz, M. Vucur +8 more
2019Disease Markers12 citations Open access
Semantic Scholar
Serum levels of kisspeptin are elevated in critically ill patients
M. Luedde, M. Spehlmann, H. Hippe, S. Loosen +9 more
2018PLoS ONE12 citations Open access
Semantic Scholar
S1030 Predictors of Response and Remission to Certolizumab Pegol in Patients With Crohn's Disease: Data From the WELCOME Study
W. Sandborn, M. Abreu, G. D'Haens, J. Colombel +8 more
201012 citations Open access
Semantic Scholar
143 Welcome: A Randomized, Double-Blind, Controlled Trial Comparing Certolizumab Pegol 400 Mg Every 2 Weeks with Every 4 Weeks for Maintenance of Response and Remission in Patients with Moderate to Severe Crohn's Disease with Secondary Failure to Infliximab
W. Sandborn, S. Vermeire, G. D'Haens, J. Colombel +7 more
200910 citations
Semantic Scholar
Low extracellular vesicle concentrations predict survival in patients with heart failure
David Schöler, S. Loosen, T. Wirtz, J. Brozat +7 more
2023Frontiers in Cardiovascular Medicine9 citations Open access
Semantic Scholar
Progress in heart failure treatment in Germany
M. Luedde, M. Spehlmann, N. Frey
2018Clinical Research in Cardiology9 citations
Semantic Scholar
Elevated serum levels of bone sialoprotein (BSP) predict long-term mortality in patients with pancreatic adenocarcinoma
S. Loosen, Pia Hoening, Niklas Puethe, M. Luedde +9 more
2019Scientific Reports8 citations Open access
Semantic Scholar
A Combined Score of Circulating miRNAs Allows Outcome Prediction in Critically Ill Patients
C. Roderburg, Fabian Benz, A. Koch, S. Loosen +7 more
2019Journal of Clinical Medicine8 citations Open access
Semantic Scholar
Elevated serum levels of bone sialoprotein during ICU treatment predict long-term mortality in critically ill patients
M. Luedde, Sanchari Roy, H. Hippe, D. V. Cardenas +10 more
2018Scientific Reports6 citations Open access
Semantic Scholar
P067 Natalizumab Induces Sustained Response and Remission in Crohn's Patients With Previous Infliximab Failure: Results From The Encore Trial
M. Spehlmann, B. Feagan, R. Fedorak, B. Lashner +7 more
20075 citations Open access
Semantic Scholar
Natalizumab Does Not Require the Concomitant Use of Immunosuppressants or Corticosteriods for the Induction of Sustained Response and Remission in Patients with Crohnʼs Disease: 1025
D. Wolf, J. Colombel, R. Enns, B. Feagan +15 more
20073 citations
Semantic Scholar
Prevention and treatment of venous thromboembolism in cancer patients
M. Spehlmann, N. Frey, O. Müller
2020Herz2 citations
Semantic Scholar
Corrigendum to: Identification of Disease-associated Traits and Clonotypes in the T Cell Receptor Repertoire of Monozygotic Twins Affected by Inflammatory Bowel Diseases
E. Rosati, M. Pogorelyy, C. Dowds, F. Møller +8 more
2020Journal of Crohn's & Colitis2 citations Open access
Semantic Scholar
Whole genome and exome sequencing of monozygotic twins discordant for Crohn’s disease
B. Petersen, M. Spehlmann, A. Raedler, Björn Stade +5 more
2014BMC Genomics2 citations Open access
Semantic Scholar
S1724 P53 Deficiency is Protective Against Acute Intestinal Damage Through Increased Interleukin-6 Production in a Mouse Model of Acute Colitis
M. Spehlmann, F. Greten, Farid K. Abdelmalak, Linus Y. Liu +4 more
20102 citations Open access
Semantic Scholar
Regain of Response and Remission by Dose Adjustment in Patients with Crohnʼs Disease Who Responded to Certolizumab Pegol: Results from the WELCOME Study: 1214
W. Sandborn, G. D'Haens, S. Vermeire, J. Colombel +7 more
20092 citations
Semantic Scholar
Efficacy of Certolizumab Pegol is Not Affected by Baseline Anti-infliximab Antibody Status in Patients with Crohnʼs Disease with Secondary Infliximab Failure: 1217
W. Sandborn, S. Vermeire, G. D'Haens, J. Colombel +7 more
20092 citations
Semantic Scholar
Lesion-Forming Bacterial Pathogen Diarrhea Caused by an Attaching/Effacing Influx Protects against Colitis-Associated CXCR2-Dependent Mucosal Neutrophil
M. Spehlmann, Sara M. Dann, P. Hruz, Elaine M. Hanson +2 more
20092 citations
Semantic Scholar
Integration of problem-oriented learning into skills lab of echocardiography: A successful tool to enhance comprehension of internal medicine
M. Spehlmann, M. Eden, N. Frey, M. Lüdde
2017Medical Teacher1 citations
Semantic Scholar
Efficacy of certolizumab pegol in Crohnʼs disease patients with secondary failure to infliximab is not affected by concommittant medications: P-0035.
W. J. Sandborn, S. Vermerie, M. Abreu, G. D'Haens +8 more
20091 citations
Semantic Scholar
Efficacy of Certolizumab Pegol in Crohnʼs Disease Patients with Secondary Failure to Infliximab Is Not Affected by Concomitant Medications: 1216
W. Sandborn, S. Vermeire, M. Abreu, G. D'Haens +8 more
20091 citations
Semantic Scholar
Natalizumab is effective without the concomitant use of immunosuppressants or corticosteroids for the induction and maintenance of response and remission in patients with Crohnʼs disease: P-069.
D. Wolf, B. Feagan, R. Fedorak, B. Lashner +8 more
20081 citations
Semantic Scholar
Natalizumab Induces Sustained Response and Remission in the Absence of Concomitant Immunosuppressants in Patients with Crohnʼs Disease Who Failed Prior Anti-TNFα Therapy: 1022
B. Lashner, J. Colombel, Robert Enns, B. Feagan +15 more
20071 citations
Semantic Scholar

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