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S. Targan · SciRah

Researcher profile · Semantic Scholar

S. Targan

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S. Targan — researcher profile on SciRah

h-index: 117
Works: 789
Citations: 58K

Most-cited papers

Ustekinumab as Induction and Maintenance Therapy for Ulcerative Colitis.
B. Sands, W. Sandborn, R. Panaccione, C. O'Brien +12 more
2019New England Journal of Medicine956 citations Open access
Semantic Scholar
Malassezia is Associated with Crohn’s Disease and Exacerbates Colitis in Mouse Models
Jose J. Limon, Jie Tang, Dalin Li, Andrea J. Wolf +15 more
2019Cell Host and Microbe398 citations Open access
Semantic Scholar
Five-year Efficacy and Safety of Ustekinumab Treatment in Crohn’s Disease: the IM-UNITI trial
W. Sandborn, R. Rebuck, Yu-Hua Wang, B. Zou +10 more
2021Clinical Gastroenterology and Hepatology209 citations Open access
Semantic Scholar
Altered Intestinal ACE2 Levels Are Associated With Inflammation, Severe Disease, and Response to Anti-Cytokine Therapy in Inflammatory Bowel Disease
Alka A. Potdar, S. Dube, Takeo Naito, Katherine Li +15 more
2020Gastroenterology61 citations Open access
Semantic Scholar
Epithelial endoplasmic reticulum stress orchestrates a protective IgA response
J. Grootjans, N. Krupka, S. Hosomi, J. D. Matute +27 more
2019Science60 citations Open access
Semantic Scholar
Higher Intra-Abdominal Visceral Adipose Tissue Mass Is Associated With Lower Rates of Clinical and Endoscopic Remission in Patients With Inflammatory Bowel Diseases Initiating Biologic Therapy: Results of the Constellation Study
A. Yarur, A. Bruss, A. Moosreiner, P. Beniwal-Patel +8 more
2023Gastroenterology59 citations Open access
Semantic Scholar
Ustekinumab is effective and safe for ulcerative colitis through 2 years of maintenance therapy
R. Panaccione, S. Danese, W. Sandborn, C. O'Brien +13 more
2020Alimentary Pharmacology and Therapeutics56 citations Open access
Semantic Scholar
Comprehensive association analyses of extraintestinal manifestations in inflammatory bowel disease
M. Khrom, Millie D. Long, S. Dube, L. Robbins +31 more
2024Gastroenterology53 citations Open access
Semantic Scholar
Effect and Mechanism of TL1A Expression on Epithelial-Mesenchymal Transition during Chronic Colitis-Related Intestinal Fibrosis
Wen-Xiu Jia, Ming-Yue Yang, Fei Han, Yu-Xin Luo +7 more
2021Mediators of Inflammation42 citations Open access
Semantic Scholar
Safety and efficacy of the anti-TL1A monoclonal antibody tulisokibart for Crohn's disease: a phase 2a induction trial.
B. Feagan, B. Sands, Corey A. Siegel, M. Dubinsky +21 more
2025The Lancet Gastroenterology and Hepatology30 citations
Semantic Scholar
Decreased Antibody Responses to Ad26.COV2.S Relative to SARS-CoV-2 mRNA Vaccines in Patients With Inflammatory Bowel Disease
V. Pozdnyakova, Gregory J. Botwin, K. Sobhani, J. Prostko +46 more
2021Gastroenterology30 citations Open access
Semantic Scholar
A role for BATF3 in TH9 differentiation and T cell driven mucosal pathologies
Masato Tsuda, Hussein Hamade, L. Thomas, Brenda C. Salumbides +11 more
2019Mucosal Immunology30 citations Open access
Semantic Scholar
COMBINATION THERAPY WITH IMMUNOMODULATORS IMPROVES THE PHARMACOKINETICS OF INFLIXIMAB BUT NOT VEDOLIZUMAB OR USTEKINUMAB.
A. Yarur, Dermot T. McGovern, M. Abreu, A. Cheifetz +7 more
2022Clinical Gastroenterology and Hepatology29 citations Open access
Semantic Scholar
Development of Physiologically Responsive Human iPSC-Derived Intestinal Epithelium to Study Barrier Dysfunction in IBD
J. Gleeson, Hannah Q. Estrada, Michifumi Yamashita, C. Svendsen +2 more
2020International Journal of Molecular Sciences29 citations Open access
Semantic Scholar
Reduced expression of COVID-19 host receptor, ACE2 is associated with small bowel inflammation, more severe disease, and response to anti-TNF therapy in Crohn’s disease
Alka A. Potdar, S. Dube, Takeo Naito, Gregory J. Botwin +12 more
2020medRxiv27 citations Open access
Semantic Scholar
Hypoalbuminemia and Bandemia Predict Failure of Infliximab Rescue Therapy in Acute Severe Ulcerative Colitis
Gaurav Syal, L. Robbins, A. Kashani, Nirupama Bonthala +7 more
2020Digestive Diseases and Sciences26 citations
Semantic Scholar
Crohn’s disease in endoscopic remission, obesity, and cases of high genetic risk demonstrates overlapping shifts in the colonic mucosal-luminal interface microbiome
J. Jacobs, M. Goudarzi, V. Lagishetty, Dalin Li +15 more
2022Genome Medicine24 citations Open access
Semantic Scholar
Efficacy and Safety of Ustekinumab as Maintenance Therapy in Ulcerative Colitis: Week 44 Results from UNIFI
B. Sands, W. Sandborn, R. Panaccione, C. O'Brien +10 more
2019Zeitschrift für Gastroenterologie - German Journal of Gastroenterology23 citations Open access
Semantic Scholar
Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn’s disease and leads to impaired CFB cleavage and phagocytosis
Marzieh Akhlaghpour, T. Haritunians, Shyam K. More, L. Thomas +40 more
2023Gut22 citations Open access
Semantic Scholar
Modeling Intestinal Epithelial Response to Interferon-γ in Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids
M. Workman, Elissa J. Troisi, S. Targan, C. Svendsen +1 more
2020International Journal of Molecular Sciences21 citations Open access
Semantic Scholar
TNF-Like Ligand 1 Aberrance Aggravates Nonalcoholic Steatohepatitis via M1 Macrophage Polarization
Yu-Xin Luo, Jin-Bo Guo, W. Jia, Mengyao Wu +5 more
2021Oxidative Medicine and Cellular Longevity19 citations Open access
Semantic Scholar
Development of a Personalized Intestinal Fibrosis Model Using Human Intestinal Organoids Derived From Induced Pluripotent Stem Cells
Hannah Q. Estrada, Shachi Patel, S. Rabizadeh, D. Casero +2 more
2021Inflammatory Bowel Diseases19 citations Open access
Semantic Scholar
Pre-Pouch Ileitis is Associated with Development of Crohn's Disease-Like Complications and Pouch Failure.
Gaurav Syal, Ronit Shemtov, Nirupama Bonthala, E. Vasiliauskas +7 more
2020Journal of Crohn's & Colitis18 citations Open access
Semantic Scholar
Ileal Gene Expression Data from Crohn's Disease Small Bowel Resections Indicate Distinct Clinical Sub-Groups.
Alka A. Potdar, Dalin Li, T. Haritunians, K. VanDussen +7 more
2019Journal of Crohn's & Colitis17 citations Open access
Semantic Scholar
Prevalence and associations of avascular necrosis of the hip in a large well-characterized cohort of patients with inflammatory bowel disease
V. Rolston, A. Patel, T. Learch, Dalin Li +6 more
2019Journal of clinical rheumatology17 citations Open access
Semantic Scholar
DR3 Regulates Intestinal Epithelial Homeostasis and Regeneration After Intestinal Barrier Injury
Y. Shimodaira, Shyam K. More, Hussein Hamade, Anna Y. Blackwood +11 more
2023Cellular and Molecular Gastroenterology and Hepatology16 citations Open access
Semantic Scholar
Efficacy in Biologic Failure and Nonbiologic-Failure Populations in a Phase 3 Study of Ustekinumab in Moderate-Severe Ulcerative Colitis: UNIFI
B. Sands, L. Peyrin-Biroulet, C. Marano, C. O'Brien +10 more
2019Zeitschrift für Gastroenterologie - German Journal of Gastroenterology15 citations Open access
Semantic Scholar
Preoperative Serum Vedolizumab Levels Do Not Impact Postoperative Outcomes in Inflammatory Bowel Disease
Aaron B. Parrish, N. Lopez, Adam Truong, K. Zaghiyan +9 more
2021Diseases of the Colon & Rectum12 citations
Semantic Scholar
BATF3 Protects Against Metabolic Syndrome and Maintains Intestinal Epithelial Homeostasis
Hussein Hamade, Jasmine Stamps, Dalton T. Stamps, Shyam K. More +9 more
2022Frontiers in Immunology9 citations Open access
Semantic Scholar
Evolution of symptoms after ustekinumab induction therapy in patients with Crohn's disease.
J. Colombel, B. Sands, C. Gasink, B. Yeager +9 more
2023Clinical Gastroenterology and Hepatology7 citations Open access
Semantic Scholar
Double-Balloon Endoscopy in Crohn Disease: A Tertiary Referral Center Experience.
B. Halloran, L. Jamil, S. Lo, M. Reeson +5 more
2020Inflammatory Bowel Diseases7 citations
Semantic Scholar
Diagnostic and therapeutic potential of RNASET2 in Crohn’s disease: Disease-risk polymorphism modulates allelic-imbalance in expression and circulating protein levels and recombinant-RNASET2 attenuates pro-inflammatory cytokine secretion
Eva Biener-Ramanujan, Florian Rosier, Simon G. Coetzee, D. McGovern +3 more
2022Frontiers in Immunology5 citations Open access
Semantic Scholar
A blood-based transcriptomic signature stratifies severe Crohn’s disease and defines potentially targetable therapeutic pathways
R. Gonsky, Evan D. Adams, Alka A. Potdar, Gregory J. Botwin +5 more
2023Frontiers in Gastroenterology4 citations Open access
Semantic Scholar
DEVELOPMENT OF A PERSONALIZED MODEL OF INTESTINAL FIBROSIS USING HUMAN INTESTINAL ORGANOIDS DERIVED FROM INDUCED PLURIPOTENT STEM CELLS
Hannah Q. Estrada, Shachi Patel, S. Rabizadeh, S. Targan +1 more
2021Gastroenterology4 citations
Semantic Scholar
Correction: Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population
M. Rivas, B. Avila, J. Koskela, Hai-Liang Huang +53 more
2019PLoS Genetics4 citations Open access
Semantic Scholar
Comparative Persistence of Non-tumor Necrosis Factor (TNF) vs. TNF Antagonists for Post-operative Prophylaxis in Crohn’s Disease (CD)
Phillip Gu, S. Dube, Yoojin Lee, Shaohong Yang +12 more
2023Digestive Diseases and Sciences3 citations Open access
Semantic Scholar
Performance Characteristics of a Clinical Decision Support Tool for Disease Complications in Crohn’s Disease
C. Siegel, L. Siegel, M. Dubinsky, S. Targan +8 more
2021Crohn's & Colitis 3603 citations Open access
Semantic Scholar
S0645 Efficacy and Safety of Ustekinumab for Crohn's Disease Through 5 Years: Final Results From the IM-UNITI Long-Term Extension
W. Sandborn, P. Rutgeerts, J. Lynch, R. Rebuck +11 more
20203 citations
Semantic Scholar
P317 Characterisation of patients with delayed response to ustekinumab for Crohn’s disease
B. Sands, A. Oortwijn, N. Rijnders, J. Izanec +9 more
2019Journal of Crohn's & Colitis3 citations Open access
Semantic Scholar
P034 EFFICACY OF USTEKINUMAB IN CROHN’S DISEASE AT MAINTENENCE WEEK 56: IM-UNITI STUDY
W. Sandborn, B. Sands, J. Colombel, C. Gasink +9 more
2019Gastroenterology3 citations Open access
Semantic Scholar
Tu1739 – Efficacy and Safety of Ustekinumab Through Week 16 in Patients with Moderate to Severe Ulcerative Colitis Randomized to Ustekinumab: Results from the Unifi Induction Trial
S. Danese, B. Sands, C. O'Brien, Hong-Yan Zhang +9 more
2019Gastroenterology3 citations Open access
Semantic Scholar
TL1A: A model for a precision medicine approach in the treatment of Crohn's disease and ulcerative colitis.
Janine Bilsborough, S. Targan
2024Advances in Pharmacology2 citations
Semantic Scholar
Su457 DOES PREOPERATIVE SERUM USTEKINUMAB CONCENTRATION PREDICT THIRTY-DAY POSTOPERATIVE OUTCOMES IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE UNDERGOING ABDOMINAL SURGERY?
Rashmi Kumar, Gaurav Syal, C. Ha, G. Melmed +7 more
20212 citations
Semantic Scholar
Tu1723 – Identification of Risk Factors Associated with Loss of Response to Ustekinumab in Crohn's Disease
S. Hanauer, B. Sands, B. Feagan, A. Oortwijn +12 more
2019Gastroenterology2 citations Open access
Semantic Scholar
Crohn’s disease in endoscopic remission, obesity, and cases of high genetic risk demonstrate overlapping shifts in the colonic mucosal-luminal interface microbiome
J. Jacobs, M. Goudarzi, V. Lagishetty, Dalin Li +15 more
2022Genome Medicine1 citations Open access
Semantic Scholar
Su1097 TL1A-MEDIATED BACTERIAL TRANSCYTOSIS BY A MLCK SPLICING VARIANT CONTRIBUTES TO INFLAMMATORY BOWEL DISEASE
Yu-Chen Pai, David Q. Shih, S. Targan, J. Turner +2 more
2020Gastroenterology1 citations
Semantic Scholar
Tu1725 – Characterization of Patients with Delayed Response to Ustekinumab for Crohn's Disease
B. Sands, A. Oortwijn, N. Rijnders, J. Izanec +9 more
2019Gastroenterology1 citations
Semantic Scholar
Su1856 – A Pilot Study Comparing Postoperative Outcomes After Ustekinumab in Patients with Inflammatory Bowel Disease
Aaron B. Parrish, K. Zaghiyan, G. Melmed, D. McGovern +4 more
2019Gastroenterology1 citations
Semantic Scholar
Sa1817 HIGHER SERUM TUMOR NECROSIS FACTOR AND INTERLEUKIN-6 LEVELS ARE ASSOCIATED WITH NON-RESPONSE TO BIOLOGIC THERAPY IN PATIENTS WITH INFLAMMATORY BOWEL DISEASES AND HIGH VISCERAL ADIPOSE TISSUE
A. Yarur, G. Melmed, A. Bruss, P. Beniwal-Patel +7 more
2023Gastroenterology0 citations
Semantic Scholar
Sa1802 COMPLEX PERIANAL CROHN'S DISEASE - ASSOCIATED WITH STRICTURING & PENETRATING PHENOTYPE, IBD SEROLOGIES, GENETIC VARIATIONS, AND PATHOGEN-DRIVEN, TH1/TH2, AND IL-23 SIGNALING PATHWAYS
Sanket S. Patel, S. Dube, T. Haritunians, Shaohong Yang +11 more
2023Gastroenterology0 citations
Semantic Scholar

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C. Gasink — researcher profile on SciRah