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Laura Baranello · SciRah

Researcher profile · Semantic Scholar

Laura Baranello

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Laura Baranello — researcher profile on SciRah

h-index: 24
Works: 53
Citations: 2,908

Most-cited papers

The Energetics and Physiological Impact of Cohesin Extrusion
Laura Vian, A. Pękowska, Suhas S. P. Rao, Kyong-Rim Kieffer-Kwon +29 more
2018Cell433 citations Open access
Semantic Scholar
Transcription dependent dynamic supercoiling is a short-range genomic force
Fedor Kouzine, Ashutosh Gupta, Laura Baranello, Damian Wójtowicz +4 more
2013Nature Structural &Molecular Biology316 citations Open access
Semantic Scholar
RNA Polymerase II Regulates Topoisomerase 1 Activity to Favor Efficient Transcription
Laura Baranello, Damian Wójtowicz, Kai-Rong Cui, B. N. Devaiah +16 more
2016Cell272 citations Open access
Semantic Scholar
Permanganate/S1 nuclease footprinting reveals non-B DNA structures with regulatory potential across a mammalian genome
Fedor Kouzine, Damian Wójtowicz, Laura Baranello, Arito Yamane +7 more
2017Cell Systems200 citations Open access
Semantic Scholar
Myc regulates chromatin decompaction and nuclear architecture during B cell activation
Kyong-Rim Kieffer-Kwon, Keisuke Nimura, Suhas S. P. Rao, Jianliang Xu +34 more
2017Molecules and Cells190 citations Open access
Semantic Scholar
The energetics and physiological impact of cohesin extrusion
Laura Vian, A. Pękowska, Suhas S. P. Rao, Kyong-Rim Kieffer-Kwon +29 more
2018Cell155 citations Open access
Semantic Scholar
MYC protein stability is negatively regulated by BRD4
B. N. Devaiah, J. Mu, Ben Akman, S. Uppal +6 more
2020Proceedings of the National Academy of Sciences of the United States of America144 citations Open access
Semantic Scholar
Spatial chromosome folding and active transcription drive DNA fragility and formation of oncogenic MLL translocations
H. Gothe, Britta A. M. Bouwman, E. Gusmão, Rossana Piccinno +16 more
2018bioRxiv128 citations Open access
Semantic Scholar
The importance of being supercoiled: how DNA mechanics regulate dynamic processes
Laura Baranello, David Levens, Ashutosh Gupta, Fedor Kouzine
2012Biochimica et Biophysica Acta101 citations Open access
Semantic Scholar
MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome”
Subhendu K. Das, Vladislav Kuzin, Donald P. Cameron, S. Sanford +12 more
2021Molecules and Cells90 citations Open access
Semantic Scholar
ChIP bias as a function of cross-linking time
Laura Baranello, Fedor Kouzine, S. Sanford, David Levens
2015Chromosome Research84 citations Open access
Semantic Scholar
DNA Break Mapping Reveals Topoisomerase II Activity Genome-Wide
Laura Baranello, Fedor Kouzine, Damian Wójtowicz, Kai-Rong Cui +3 more
2014International Journal of Molecular Sciences81 citations Open access
Semantic Scholar
DNA topoisomerase I inhibition by camptothecin induces escape of RNA polymerase II from promoter-proximal pause site, antisense transcription and histone acetylation at the human HIF-1α gene locus
Laura Baranello, D. Bertozzi, M. Fogli, Y. Pommier +1 more
2009Nucleic Acids Research71 citations Open access
Semantic Scholar
Global inhibition with specific activation: how p53 and MYC redistribute the transcriptome in the DNA double-strand break response
Joshua R. Porter, Brian E. Fisher, Laura Baranello, Julia C. Liu +7 more
2017Molecules and Cells70 citations Open access
Semantic Scholar
GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in Individuals with DNA Repair-Proficient Trichothiodystrophy.
C. Kuschal, Elena Botta, D. Orioli, J. DiGiovanna +17 more
2016American Journal of Human Genetics61 citations Open access
Semantic Scholar
Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate PLK1
Helena Silva Cascales, Kamila Burdová, A. Middleton, Vladislav Kuzin +5 more
2017Life Science Alliance60 citations Open access
Semantic Scholar
The effects of camptothecin on RNA polymerase II transcription: roles of DNA topoisomerase I.
G. Capranico, F. Ferri, M. Fogli, A. Russo +2 more
2007Biochimie56 citations Open access
Semantic Scholar
DNA topology and transcription
Fedor Kouzine, D. Levens, Laura Baranello
2014The Nucleus52 citations Open access
Semantic Scholar
Dissecting the transcriptional functions of human DNA topoisomerase I by selective inhibitors: implications for physiological and therapeutic modulation of enzyme activity.
G. Capranico, Jessica Marinello, Laura Baranello
2010Biochimica et Biophysica Acta46 citations
Semantic Scholar
DNA Supercoiling, Topoisomerases, and Cohesin: Partners in Regulating Chromatin Architecture?
Camilla Björkegren, Laura Baranello
2018International Journal of Molecular Sciences31 citations Open access
Semantic Scholar
DNA Topoisomerases
Laura Baranello, Fedor Kouzine, David Levens
2013Transcription31 citations Open access
Semantic Scholar
Control of protein synthesis through mRNA pseudouridylation by dyskerin
C. Pederiva, Davide M Trevisan, D. Peirasmaki, Shan Chen +6 more
2023Science Advances30 citations Open access
Semantic Scholar
Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1.
Anika Wiegard, Vladislav Kuzin, Donald P. Cameron, J. Grosser +12 more
2021Molecules and Cells27 citations Open access
Semantic Scholar
CTCF and cohesin cooperate to organize the 3D structure of the mammalian genome
Laura Baranello, Fedor Kouzine, David Levens
2014Proceedings of the National Academy of Sciences of the United States of America25 citations Open access
Semantic Scholar
Topoisomerase Regulation of Cancer Gene Expression.
Laura Baranello, Fedor Kouzine, D. Levens
2025Annual Review of Biochemistry19 citations Open access
Semantic Scholar
NEDDylated Cullin 3 mediates the adaptive response to topoisomerase 1 inhibitors
A. Meroni, J. Grosser, Sumedha Agashe, Natasha Ramakrishnan +4 more
2022Science Advances19 citations Open access
Semantic Scholar
MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner
A. Castell, Qinzi Yan, K. Fawkner, Wesam Bazzar +18 more
2022Cancer Research Communications17 citations Open access
Semantic Scholar
Controlling gene expression by DNA mechanics: emerging insights and challenges
D. Levens, Laura Baranello, Fedor Kouzine
2016Biophysical Reviews17 citations Open access
Semantic Scholar
The Epstein-Barr virus deubiquitinating enzyme BPLF1 regulates the activity of topoisomerase II during productive infection
Jin-Lin Li, N. Nagy, Jiangnan Liu, Soham Gupta +5 more
2021PLoS Pathogens16 citations Open access
Semantic Scholar
Controlling gene expression by DNA mechanics: emerging insights and challenges
D. Levens, Laura Baranello, Fedor Kouzine
2016Biophysical Reviews16 citations Open access
Semantic Scholar
Coinhibition of topoisomerase 1 and BRD4-mediated pause release selectively kills pancreatic cancer via readthrough transcription
Donald P. Cameron, J. Grosser, S. Ladigan, Vladislav Kuzin +21 more
2023bioRxiv15 citations Open access
Semantic Scholar
TOP1 CAD-seq: A protocol to map catalytically engaged topoisomerase 1 in human cells
Vladislav Kuzin, Anika Wiegard, Donald P. Cameron, Laura Baranello
2022STAR Protocols9 citations Open access
Semantic Scholar
The Use of Psoralen Photobinding to Study Transcription-Induced Supercoiling
Fedor Kouzine, Laura Baranello, D. Levens
2018Methods in molecular biology9 citations Open access
Semantic Scholar
Mapping DNA Breaks by Next-Generation Sequencing
Laura Baranello, Fedor Kouzine, Damian Wójtowicz, Kai-Rong Cui +4 more
2018Methods in molecular biology7 citations
Semantic Scholar
Epigenetic control of topoisomerase 1 activity presents a cancer vulnerability
Tae-Hee Lee, Colina X Qiao, Vladislav Kuzin, Yuepeng Shi +10 more
2025Nature Communications4 citations Open access
Semantic Scholar
Epigenetic control of Topoisomerase 1 activity presents a cancer vulnerability
Tae-Hee Lee, Colina X Qiao, Vladislav Kuzin, Yuepeng Shi +7 more
2024bioRxiv4 citations Open access
Semantic Scholar
Analysis of Myc Chromatin Binding by Calibrated ChIP-Seq Approach.
Donald P. Cameron, Vladislav Kuzin, Laura Baranello
2021Methods in molecular biology4 citations
Semantic Scholar
Localised activity of reverse gyrase at gene regulatory elements
Paul Villain, Vladislav Kuzin, Augustin Darennes-Degaugue, Florence Lorieux +5 more
2025bioRxiv1 citations Open access
Semantic Scholar
Deficiency of Polη in Saccharomyces cerevisiae reveals the impact of transcription on damage-induced cohesion
Pei-Shang Wu, J. Grosser, Donald P. Cameron, Laura Baranello +1 more
2021PLoS Genetics1 citations Open access
Semantic Scholar
3 – DNA Supercoiling(omics)
Laura Baranello, D. Levens, Fedor Kouzine
20181 citations
Semantic Scholar
Arginine methylation of human DNA topoisomerase I by PRMT5 facilitates DNA relaxation
Saini Basu, Arpan Bhattacharyya, M. A. Khan, Uttam Pal +5 more
2026Nucleic Acids Research0 citations Open access
Semantic Scholar
Tales of destruction and repair: the changing view of MYC proteins in tumorigenesis.
Laura Baranello, Dimitrios Papadopoulos, M. Eilers
2026Genes & Development0 citations Open access
Semantic Scholar
MYC modulates TOP2A diffusion to promote substrate detection and activity
Donald P. Cameron, Kathryn Jackson, A. Loffreda, Carl Möller +12 more
2025bioRxiv0 citations Open access
Semantic Scholar
Abstract A024: Epigenetic control of topoisomerase 1 activity presents a cancer vulnerability
Tae-Hee Lee, Xuan C. Qiao, Tongyu Wu, Vladislav Kuzin +4 more
2024Cancer Research0 citations
Semantic Scholar
CTNI-58. IMPROVING TRIAL ACCESS FOR PEOPLE WITH RARE CNS TUMORS: AN NCI-CONNECT PHASE I/II TRIAL OF PLX038 IN TUMORS WITH MYC/MYCN AMPLIFICATIONS INCORPORATING CORRELATIVE STUDIES AND PATIENT REPORTED OUTCOMES
M. Penas-Prado, J. Wooley, Jinkyu Jung, Ying Yuan +11 more
2022Neuro-Oncology0 citations Open access
Semantic Scholar
The Epstein-Barr virus ubiquitin deconjugase BPLF1 regulates the activity of Topoisomerase II during virus replication
Jin-Lin Li, N. Nagy, Jiangnan Liu, Soham Gupta +5 more
2021bioRxiv0 citations Open access
Semantic Scholar
The assisting role of Polη in transcription facilitates formation of damage-induced cohesion
Pei-Shang Wu, Donald P. Cameron, J. Grosser, Laura Baranello +1 more
2020bioRxiv0 citations Open access
Semantic Scholar
The Role of DNA Topology and Conformation in Gene Regulation, In Vivo
D. Levens, Fedor Kouzine, Laura Baranello
20180 citations Open access
Semantic Scholar
Controlling gene expression by DNA mechanics: emerging insights and challenges
D. Levens, Laura Baranello, Fedor Kouzine
2016Biophysical Reviews0 citations Open access
Semantic Scholar
Controlling gene expression by DNA mechanics: emerging insights and challenges
D. Levens, Laura Baranello, Fedor Kouzine
2016Biophysical Reviews0 citations Open access
Semantic Scholar

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Fedor Kouzine×20
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Fedor Kouzine — researcher profile on SciRah
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Vladislav Kuzin×11
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David Levens — researcher profile on SciRah

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