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Fiorenza Stagni · SciRah

Researcher profile · Semantic Scholar

Fiorenza Stagni

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Fiorenza Stagni — researcher profile on SciRah

h-index: 17
Works: 47
Citations: 1,060

Most-cited papers

Neurogenesis impairment: An early developmental defect in Down syndrome
Fiorenza Stagni, Andrea Giacomini, M. Emili, S. Guidi +1 more
2018Free Radical Biology & Medicine106 citations
Semantic Scholar
Timing of therapies for Down syndrome: the sooner, the better
Fiorenza Stagni, Andrea Giacomini, S. Guidi, E. Ciani +1 more
2015Frontiers in Behavioral Neuroscience105 citations Open access
Semantic Scholar
Prenatal pharmacotherapy rescues brain development in a Down's syndrome mouse model.
S. Guidi, Fiorenza Stagni, P. Bianchi, E. Ciani +8 more
2014Brain : a journal of neurology84 citations
Semantic Scholar
Early Pharmacotherapy with Fluoxetine Rescues Dendritic Pathology in the Ts65Dn Mouse Model of Down Syndrome
S. Guidi, Fiorenza Stagni, P. Bianchi, E. Ciani +6 more
2013Brain Pathology73 citations Open access
Semantic Scholar
Short- and long-term effects of neonatal pharmacotherapy with epigallocatechin-3-gallate on hippocampal development in the Ts65Dn mouse model of Down syndrome.
Fiorenza Stagni, Andrea Giacomini, M. Emili, S. Trazzi +5 more
2016Neuroscience61 citations
Semantic Scholar
Treatment with the flavonoid 7,8-Dihydroxyflavone: a promising strategy for a constellation of body and brain disorders.
M. Emili, S. Guidi, B. Uguagliati, Andrea Giacomini +2 more
2020Critical reviews in food science and nutrition60 citations Open access
Semantic Scholar
A flavonoid agonist of the TrkB receptor for BDNF improves hippocampal neurogenesis and hippocampus‐dependent memory in the Ts65Dn mouse model of DS
Fiorenza Stagni, Andrea Giacomini, S. Guidi, M. Emili +6 more
2017Experimental Neurology58 citations
Semantic Scholar
Pharmacotherapy with Fluoxetine Restores Functional Connectivity from the Dentate Gyrus to Field CA3 in the Ts65Dn Mouse Model of Down Syndrome
Fiorenza Stagni, J. Magistretti, S. Guidi, E. Ciani +3 more
2013PLoS ONE55 citations Open access
Semantic Scholar
Long-term effects of neonatal treatment with fluoxetine on cognitive performance in Ts65Dn mice.
Fiorenza Stagni, Andrea Giacomini, S. Guidi, E. Ciani +5 more
2015Neurobiology of Disease51 citations Open access
Semantic Scholar
Abnormal development of the inferior temporal region in fetuses with Down syndrome
S. Guidi, Andrea Giacomini, Fiorenza Stagni, M. Emili +3 more
2018Brain Pathology42 citations Open access
Semantic Scholar
Inhibition of APP gamma-secretase restores Sonic Hedgehog signaling and neurogenesis in the Ts65Dn mouse model of Down syndrome
Andrea Giacomini, Fiorenza Stagni, S. Trazzi, S. Guidi +4 more
2015Neurobiology of Disease39 citations Open access
Semantic Scholar
The Challenging Pathway of Treatment for Neurogenesis Impairment in Down Syndrome: Achievements and Perspectives
Fiorenza Stagni, R. Bartesaghi
2022Frontiers in Cellular Neuroscience28 citations Open access
Semantic Scholar
Age-related impairment of olfactory bulb neurogenesis in the Ts65Dn mouse model of Down syndrome.
P. Bianchi, Simone Bettini, S. Guidi, E. Ciani +5 more
2014Experimental Neurology24 citations
Semantic Scholar
Neuroanatomical alterations in higher-order thalamic nuclei of fetuses with Down syndrome.
Fiorenza Stagni, Andrea Giacomini, M. Emili, B. Uguagliati +3 more
2020Clinical neurology and neurosurgery (Dutch-Flemish ed. Print)21 citations Open access
Semantic Scholar
Subicular hypotrophy in fetuses with Down syndrome and in the Ts65Dn model of Down syndrome
Fiorenza Stagni, Andrea Giacomini, M. Emili, B. Uguagliati +3 more
2018Brain Pathology21 citations Open access
Semantic Scholar
Impaired Brain Mitochondrial Bioenergetics in the Ts65Dn Mouse Model of Down Syndrome Is Restored by Neonatal Treatment with the Polyphenol 7,8-Dihydroxyflavone
D. Valenti, Fiorenza Stagni, M. Emili, S. Guidi +2 more
2021Antioxidants20 citations Open access
Semantic Scholar
SNX27, a protein involved in down syndrome, regulates GPR17 trafficking and oligodendrocyte differentiation
V. Meraviglia, A. Ulivi, M. Boccazzi, F. Valenza +9 more
2016Glia20 citations Open access
Semantic Scholar
Timing of Treatment with the Flavonoid 7,8-DHF Critically Impacts on Its Effects on Learning and Memory in the Ts65Dn Mouse
Andrea Giacomini, Fiorenza Stagni, M. Emili, B. Uguagliati +3 more
2019Antioxidants17 citations Open access
Semantic Scholar
Neonatal therapy with clenbuterol and salmeterol restores spinogenesis and dendritic complexity in the dentate gyrus of the Ts65Dn model of Down syndrome.
M. Emili, Fiorenza Stagni, M. Salvalai, B. Uguagliati +6 more
2020Neurobiology of Disease16 citations Open access
Semantic Scholar
Treatment with corn oil improves neurogenesis and cognitive performance in the Ts65Dn mouse model of Down syndrome.
Andrea Giacomini, Fiorenza Stagni, M. Emili, S. Guidi +5 more
2018Brain Research Bulletin16 citations Open access
Semantic Scholar
Neuroanatomical alterations and synaptic plasticity impairment in the perirhinal cortex of the Ts65Dn mouse model of Down syndrome.
V. Roncacè, Costanza Burattini, Fiorenza Stagni, S. Guidi +4 more
2017Neurobiology of Disease16 citations Open access
Semantic Scholar
Long-term effect of neonatal inhibition of APP gamma-secretase on hippocampal development in the Ts65Dn mouse model of Down syndrome
Fiorenza Stagni, Alessandra Raspanti, Andrea Giacomini, S. Guidi +7 more
2017Neurobiology of Disease16 citations Open access
Semantic Scholar
Obstructive sleep apneas naturally occur in mice during rem sleep and are highly prevalent in a mouse model of down syndrome.
M. L. Bartolucci, C. Berteotti, S. Alvente, S. Bastianini +9 more
2021Neurobiology of Disease15 citations Open access
Semantic Scholar
Epigallocatechin gallate: A useful therapy for cognitive disability in Down syndrome?
Fiorenza Stagni, Andrea Giacomini, M. Emili, S. Guidi +2 more
2017Neurogenesis15 citations Open access
Semantic Scholar
Early Appearance of Dendritic Alterations in Neocortical Pyramidal Neurons of the Ts65Dn Model of Down Syndrome
B. Uguagliati, Fiorenza Stagni, M. Emili, Andrea Giacomini +3 more
2021Developmental Neuroscience14 citations Open access
Semantic Scholar
Neonatal treatment with cyclosporine A restores neurogenesis and spinogenesis in the Ts65Dn model of Down syndrome.
Fiorenza Stagni, M. Salvalai, Andrea Giacomini, M. Emili +5 more
2019Neurobiology of Disease14 citations Open access
Semantic Scholar
Lithium Restores Age-related Olfactory Impairment in the Ts65Dn Mouse Model of Down Syndrome.
S. Guidi, P. Bianchi, Fiorenza Stagni, Andrea Giacomini +4 more
2017CNS and Neurological Disorders - Drug Targets13 citations
Semantic Scholar
Early appearance of developmental alterations in the dendritic tree of the hippocampal granule cells in the Ts65Dn model of Down syndrome
B. Uguagliati, Abdel-Rahman Al-Absi, Fiorenza Stagni, M. Emili +4 more
2021Hippocampus12 citations Open access
Semantic Scholar
The flavonoid 7,8-DHF fosters prenatal brain proliferation potency in a mouse model of Down syndrome
Fiorenza Stagni, B. Uguagliati, M. Emili, Andrea Giacomini +2 more
2021Scientific Reports9 citations Open access
Semantic Scholar
Reversal of neurodevelopmental impairment and cognitive enhancement by pharmacological intervention with the polyphenol polydatin in a Down syndrome model.
M. Emili, Fiorenza Stagni, C. Russo, L. Angelozzi +2 more
2024Neuropharmacology7 citations Open access
Semantic Scholar
Cellularity Defects Are Not Ubiquitous in the Brains of Fetuses With Down Syndrome
M. Emili, Fiorenza Stagni, M. Bonasoni, S. Guidi +1 more
2024Developmental Neurobiology3 citations Open access
Semantic Scholar
Increased hippocampal epigenetic age in the Ts65Dn mouse model of Down Syndrome
F. Ravaioli, Fiorenza Stagni, S. Guidi, C. Pirazzini +5 more
2023bioRxiv3 citations Open access
Semantic Scholar
Dendritic phenotype and proliferation potency in the hippocampal dentate gyrus of the Ts66Yah model of down syndrome.
M. Emili, Fiorenza Stagni, S. Guidi, C. Russo +4 more
2025Neuroscience Letters1 citations Open access
Semantic Scholar
Treatment with kaempferol: A possible tool to restore neurogenesis in Down syndrome?
Fiorenza Stagni, Maria Elisa Salvalai, S. Guidi, Andrea Giacomini +4 more
2019European Neuropsychopharmacology1 citations
Semantic Scholar
Selective inhibitors of GSK-3β: a suitable therapy for Down syndrome?
Andrea Giacomini, Fiorenza Stagni, M. Emili, S. Guidi +5 more
20181 citations
Semantic Scholar
Targeting APP/AICD in Down syndrome.
S. Guidi, Fiorenza Stagni, R. Bartesaghi
2017OncoTarget1 citations Open access
Semantic Scholar
Neurogenesis in the hippocampal dentate gyrus of a Down syndrome model can be restored by neonatal treatment with an agonist of the BDNF TrkB receptor
Fiorenza Stagni, Marco Emili, Andrea Giacomini, S. Guidi +2 more
20161 citations
Semantic Scholar
Pharmacological Rescue of Dendritic Pathology in the Ts65Dn Mouse Model of Down Syndrome
Fiorenza Stagni
20141 citations
Semantic Scholar
Neonatal Treatment with Astaxanthin-Loaded Stealth Solid Lipid Nanoparticles Activates the Impaired NRF2 Pathway and Reduces Hippocampal Oxidative Stress in a Mouse Model of Trisomy 21
L. Angelozzi, Debora Santonocito, F. Flotta, B. Uguagliati +6 more
2026Cells0 citations Open access
Semantic Scholar
Promoting Research Excellence in Down Syndrome: Proceedings of the 5th International Conference of the Trisomy 21 Research Society
F. Di Domenico, M. Perluigi, A. Tramutola, M. Bacalini +39 more
2026Neuromolecular medicine0 citations Open access
Semantic Scholar
Epigallocatechin-3-gallate
Fiorenza Stagni, S. Guidi, R. Bartesaghi
2021Factors Affecting Neurodevelopment0 citations
Semantic Scholar
Neurogenesis deficits in Down syndrome: testing recovery with GABAα5 negative allosteric modulator, β2 adrenergic agonist and IGF-1 in Ts65Dn mice.
Christelle Albac, Fiorenza Stagni, Mariagrazia Grilli, Maria Elisa Salvalai +2 more
2019European Neuropsychopharmacology0 citations
Semantic Scholar
P.4.07 Prenatal therapy with a BDNF mimetic elicits a widespread rescue of neurogenesis in a mouse model of Down syndrome
Beatrice Uguagliati, Fiorenza Stagni, Andrea Giacomini, Marco Emili +2 more
2019European Neuropsychopharmacology0 citations
Semantic Scholar
Treatment with kaempferol: a possible tool to restore neurogenesis in Down syndrome?
Fiorenza Stagni
20180 citations
Semantic Scholar
Is it possible to rescue maturation of nerve cells in Down syndrome with early pharmacological treatment?
Fiorenza Stagni
20180 citations
Semantic Scholar
SNX27 REGULATES GPR17 RECYCLING AND THE KINETICS OF OLIGODENDROCYTE DIFFERENTIATION: IMPLICATION IN DOWN SYNDROME
A. Ulivi, V. Meraviglia, F. Valenza, M. Boccazzi +9 more
20170 citations
Semantic Scholar
Targeting APP/AICD in Down syndrome
S. Guidi, Fiorenza Stagni, R. Bartesaghi
2017OncoTarget0 citations Open access
Semantic Scholar

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R. Bartesaghi×40
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R. Bartesaghi — researcher profile on SciRah
S. Guidi×39
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S. Guidi — researcher profile on SciRah
Andrea Giacomini×28
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Andrea Giacomini — researcher profile on SciRah
M. Emili×25
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M. Emili — researcher profile on SciRah

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B. Uguagliati — researcher profile on SciRah

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E. Ciani — researcher profile on SciRah

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S. Trazzi — researcher profile on SciRah

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M. Salvalai — researcher profile on SciRah

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M. Grilli — researcher profile on SciRah

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P. Bianchi — researcher profile on SciRah

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L. Calzà — researcher profile on SciRah

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R. Rimondini — researcher profile on SciRah