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O. Julien · SciRah

Researcher profile · Semantic Scholar

O. Julien

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O. Julien — researcher profile on SciRah

h-index: 22
Works: 59
Citations: 2,089

Most-cited papers

Caspases and their substrates
O. Julien, J. Wells
2017Cell Death and Differentiation730 citations Open access
Semantic Scholar
Mapping Interactions with the Chaperone Network Reveals Factors that Protect Against Tau Aggregation
S. Mok, Carlo Condello, Rebecca Freilich, Anne T Gillies +13 more
2018Nature Structural & Molecular Biology137 citations Open access
Semantic Scholar
The DegraBase: A Database of Proteolysis in Healthy and Apoptotic Human Cells*
E. Crawford, Julia Seaman, Nicholas J. Agard, Gerald W. Hsu +8 more
2012Molecular & Cellular Proteomics133 citations Open access
Semantic Scholar
Comparative Analysis of Mitochondrial N-Termini from Mouse, Human, and Yeast *
S. Calvo, O. Julien, K. Clauser, Hongying Shen +3 more
2017Molecular & Cellular Proteomics94 citations Open access
Semantic Scholar
Competing protein-protein interactions regulate binding of Hsp27 to its client protein tau
Rebecca Freilich, M. Betegon, E. Tse, S. Mok +5 more
2018Nature Communications90 citations Open access
Semantic Scholar
Global cellular response to chemotherapy-induced apoptosis
Arun P. Wiita, E. Ziv, P. Wiita, A. Urisman +4 more
2013eLife69 citations Open access
Semantic Scholar
Cacidases: caspases can cleave after aspartate, glutamate and phosphoserine residues
J. Seaman, O. Julien, PS Lee, T. Rettenmaier +2 more
2016Cell Death and Differentiation68 citations Open access
Semantic Scholar
Targeting RAS-driven human cancer cells with antibodies to upregulated and essential cell-surface proteins
Alexander J. Martinko, C. Truillet, O. Julien, J. E. Díaz +7 more
2018eLife65 citations Open access
Semantic Scholar
The Unique Cofactor Region of Zika Virus NS2B-NS3 Protease Facilitates Cleavage of Key Host Proteins.
M. Hill, Anil Kumar, J. Wells, T. Hobman +2 more
2018ACS Chemical Biology56 citations
Semantic Scholar
SAR and molecular mechanics reveal the importance of ring entropy in the biosynthesis and activity of a natural product
Hai L. Tran, Katrina W. Lexa, O. Julien, T. Young +3 more
2017Journal of the American Chemical Society53 citations Open access
Semantic Scholar
SARS-CoV-2 Mpro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals
Sizhu Amelia Chen, E. Arutyunova, Jimmy Lu, Muhammad Bashir Khan +15 more
2023ACS Central Science50 citations Open access
Semantic Scholar
Highly multiplexed and quantitative cell-surface protein profiling using genetically barcoded antibodies
S. Pollock, A. Hu, Y. Mou, Alexander J. Martinko +9 more
2018Proceedings of the National Academy of Sciences of the United States of America50 citations Open access
Semantic Scholar
Unraveling the mechanism of cell death induced by chemical fibrils
O. Julien, M. Kampmann, M. Bassik, J. Zorn +8 more
2014Nature Chemical Biology49 citations Open access
Semantic Scholar
Heat Shock Protein 70 (Hsp70) Suppresses RIP1-Dependent Apoptotic and Necroptotic Cascades
S. Srinivasan, Laura C Cesa, Xiaokai Li, O. Julien +7 more
2017Molecular Cancer Research44 citations Open access
Semantic Scholar
Biochemical Tools for Tracking Proteolysis.
Long-Xiang Wang, Kimberly Main, Henry Wang, O. Julien +1 more
2021Journal of Proteome Research39 citations Open access
Semantic Scholar
Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition
M. Hill, D. MacPherson, Peng Wu, O. Julien +2 more
2016ACS Chemical Biology36 citations Open access
Semantic Scholar
Protease substrate identification using N-terminomics.
Shu Y. Luo, L. E. Araya, O. Julien
2019ACS Chemical Biology33 citations
Semantic Scholar
Differential stability of the bovine prion protein upon urea unfolding
O. Julien, S. Chatterjee, A. Thiessen, S. Graether +1 more
2009Protein Science33 citations Open access
Semantic Scholar
Myocardial MMP-2 contributes to SERCA2a proteolysis during cardiac ischemia-reperfusion injury.
A. Roczkowsky, Brandon Y. H. Chan, Tim Y. T. Lee, Zabed Mahmud +5 more
2019Cardiovascular Research31 citations Open access
Semantic Scholar
Turning ON Caspases with Genetics and Small Molecules
Charles W Morgan, O. Julien, Elizabeth K. Unger, N. Shah +1 more
2014Methods in Enzymology30 citations Open access
Semantic Scholar
Is there nascent structure in the intrinsically disordered region of troponin I?
O. Julien, P. Mercier, Claire N. Allen, Olivier Fisette +4 more
2011Proteins: Structure, Function, and Bioinformatics26 citations
Semantic Scholar
Solution Structure of a DNA Duplex Containing the Potent Anti-Poxvirus Agent Cidofovir
O. Julien, J. Beadle, Wendy C. Magee, S. Chatterjee +3 more
2011Journal of the American Chemical Society25 citations Open access
Semantic Scholar
UBC9-dependent Association between Calnexin and Protein Tyrosine Phosphatase 1B (PTP1B) at the Endoplasmic Reticulum*
Dukgyu Lee, Allison Kraus, Daniel Prins, J. Groenendyk +8 more
2015Journal of Biological Chemistry22 citations Open access
Semantic Scholar
Relative and regional stabilities of the hamster, mouse, rabbit, and bovine prion proteins toward urea unfolding assessed by nuclear magnetic resonance and circular dichroism spectroscopies.
O. Julien, S. Chatterjee, T. Bjorndahl, B. Sweeting +7 more
2011Biochemistry22 citations
Semantic Scholar
Versatile cardiac troponin chimera for muscle protein structural biology and drug discovery.
Sandra E. Pineda-Sanabria, O. Julien, B. Sykes
2014ACS Chemical Biology16 citations
Semantic Scholar
Toward protein structure in situ: comparison of two bifunctional rhodamine adducts of troponin C.
O. Julien, Yin-Biao Sun, A. C. Knowles, B. Brandmeier +5 more
2007Biophysical Journal12 citations Open access
Semantic Scholar
CaspSites: A Database and Web Application for Experimentally Observed Human Caspase Substrates Using N-Terminomics.
Henry Wang, O. Julien
2023Journal of Proteome Research11 citations
Semantic Scholar
Mayaro Virus Non-Structural Protein 2 Circumvents the Induction of Interferon in Part by Depleting Host Transcription Initiation Factor IIE Subunit 2
Ray Ishida, J. Cole, Joaquin Lopez-Orozco, N. Fayad +6 more
2021Cells10 citations Open access
Semantic Scholar
A conserved acetylation switch enables pharmacological control of tubby-like protein stability
E. Kerek, Kevin H Yoon, Shu Y. Luo, Jerry Chen +4 more
2020Journal of Biological Chemistry10 citations Open access
Semantic Scholar
The effect of the cosolvent trifluoroethanol on a tryptophan side chain orientation in the hydrophobic core of troponin C
O. Julien, P. Mercier, M. L. Crane, B. Sykes
2009Protein Science9 citations Open access
Semantic Scholar
MTH187 from Methanobacterium thermoautotrophicum has three HEAT-like Repeats
O. Julien, I. Gignac, Anne Hutton, A. Yee +2 more
2006Journal of Biomolecular NMR9 citations
Semantic Scholar
Loss of ADAM15 Exacerbates Transition to Decompensated Myocardial Hypertrophy and Dilation Through Activation of the Calcineurin Pathway
Preetinder K. Aujla, Mei Hu, Bridgette Hartley, Joshua W. Kranrod +7 more
2022HYPERTENSION8 citations Open access
Semantic Scholar
Tryptophan side chain conformers monitored by NMR and time‐resolved fluorescence spectroscopies
O. Julien, Guoli Wang, Abel Jonckheer, Y. Engelborghs +1 more
2012Proteins: Structure, Function, and Bioinformatics8 citations
Semantic Scholar
NMR studies of the dynamics of a bifunctional rhodamine probe attached to troponin C.
O. Julien, P. Mercier, L. Spyracopoulos, J. Corrie +1 more
2008Journal of the American Chemical Society8 citations
Semantic Scholar
Monitoring Prion Protein Stability by NMR
O. Julien, S. Graether, B. Sykes
2009Journal of Toxicology and Environmental Health, Part A4 citations
Semantic Scholar
Tryptophan mutants of cardiac troponin C: 3D structure, troponin I affinity, and in situ activity.
O. Julien, Yin-Biao Sun, Xu Wang, D. Lindhout +3 more
2008Biochemistry4 citations
Semantic Scholar
NOD1 is super-activated through spatially-selective ubiquitination by the Salmonella effector SspH2
Cole Delyea, Shu Y. Luo, Bradley E. Dubrule, O. Julien +1 more
2021bioRxiv2 citations Open access
Semantic Scholar
SARS-CoV-2 Mpro protease variants of concern display altered viral and host target processing but retain potency towards antivirals
Sizhu Amelia Chen, E. Arutyunova, Jimmy Lu, Muhammad Bashir Khan +15 more
2023bioRxiv1 citations Open access
Semantic Scholar
Enhanced Levels of MYHCA peptides in Mediastinal Lymph Nodes Following Myocardial Infarction: MMP-2 as a Potential Protease in the Generation of Antigenic Peptides
Zabed Mahmud, Bridgette Hartley, Greta Mattavelli, Angela Riedel +4 more
2026Journal of Molecular and Cellular Cardiology Plus0 citations Open access
Semantic Scholar
Matrix metalloproteinases proteolyze RAB proteins and contribute to cisplatin-induced ototoxicity
Zahra Zandi, Bridgette Hartley, Wesam Bassiouni, Michèle G. DuVal +6 more
2026bioRxiv0 citations Open access
Semantic Scholar
Solution NMR studies reveal novel CLIC4 chaperone activity with respect to profilin-1.
Kevin Y. L. Mak, M. Feisal, Zabed Mahmud, Philip B. Liu +6 more
2023Biophysical Journal0 citations Open access
Semantic Scholar
Proteomic approaches to assess ischemia-reperfusion (stunning) injury to the heart
Bridgette Hartley, A. Roczkowsky, Wesam Bassiouni, R. Schulz +1 more
2022Journal of Molecular and Cellular Cardiology0 citations
Semantic Scholar
Targeting RAS Driven Human Cancer Cells with Antibodies to Upregulated and 1 Essential Cell-Surface Proteins 2 3
Alexander J. Martinko, C. Truillet, O. Julien, Juan E Diaz +7 more
20180 citations
Semantic Scholar
Heat Shock Protein 70 (Hsp70) Suppresses RIP1-Dependent Apoptotic and Necroptotic Cell Death
S. Srinivasan, Laura C Cesa, Xiaokai Li, O. Julien +9 more
20170 citations
Semantic Scholar
Engineered Caspases with Altered Specificities Enable Identification of Exosites
J. Hardy, M. Hill, D. MacPherson, Peng Wu +2 more
2016The FASEB Journal0 citations
Semantic Scholar
Crystal structure of caspase-3 DEVE peptide complex
Julia Seaman, O. Julien, P. Lee, T. Rettenmaier +2 more
20160 citations
Semantic Scholar
Crystal structure of caspase-7 DEVE peptide complex
Julia Seaman, O. Julien, P. Lee, T. Rettenmaier +2 more
20160 citations
Semantic Scholar
Amide 1H and 15N chemical shift assignments and 15N relaxation parameters of the troponin C-troponin I hybrid proteins cChimeraX
S. P. Sanabria, B. Sykes, O. Julien
20140 citations
Semantic Scholar
Unraveling the Mechanism of Cell Death Induced by Chemical and Protein Fibrils
O. Julien, M. Kampmann, M. Bassik, V. Venditto +4 more
20140 citations Open access
Semantic Scholar
Author response: Global cellular response to chemotherapy-induced apoptosis
Arun P. Wiita, E. Ziv, P. Wiita, A. Urisman +4 more
20130 citations Open access
Semantic Scholar

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