Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

B. Sykes · SciRah

Researcher profile · Semantic Scholar

B. Sykes

Share profile

B. Sykes — researcher profile on SciRah

h-index: 66
Works: 472
Citations: 26K

Most-cited papers

Metabolomic profiling of asthma: diagnostic utility of urine nuclear magnetic resonance spectroscopy.
Erik J. Saude, C. Skappak, Shana Regush, K. Cook +6 more
2011Journal of Allergy and Clinical Immunology174 citations
Semantic Scholar
Targeting the sarcomere to correct muscle function
P. Hwang, B. Sykes
2015Nature reviews. Drug discovery117 citations
Semantic Scholar
Targeted expression, purification, and cleavage of fusion proteins from inclusion bodies in Escherichia coli
P. Hwang, Jonathan S Pan, B. Sykes
2014FEBS Letters106 citations
Semantic Scholar
1H NMR derived metabolomic profile of neonatal asphyxia in umbilical cord serum: implications for hypoxic ischemic encephalopathy.
S. Reinke, B. Walsh, G. Boylan, B. Sykes +3 more
2013Journal of Proteome Research72 citations
Semantic Scholar
A structural and functional perspective into the mechanism of Ca2+-sensitizers that target the cardiac troponin complex
I. M. Robertson, Yin-Biao Sun, Monica X. Li, B. Sykes
2010Journal of Molecular and Cellular Cardiology65 citations Open access
Semantic Scholar
The cardiac-specific N-terminal region of troponin I positions the regulatory domain of troponin C
P. Hwang, F. Cai, Sandra E. Pineda-Sanabria, D. C. Corson +1 more
2014Proceedings of the National Academy of Sciences of the United States of America64 citations Open access
Semantic Scholar
Mutations in the Saccharomyces cerevisiae succinate dehydrogenase result in distinct metabolic phenotypes revealed through (1)H NMR-based metabolic footprinting.
Samuel S. W. Szeto, S. Reinke, B. Sykes, B. Lemire
2010Journal of Proteome Research61 citations
Semantic Scholar
The metabolomics of asthma: novel diagnostic potential.
D. Adamko, B. Sykes, B. Rowe
2012Chest50 citations
Semantic Scholar
Structural and functional consequences of the cardiac troponin C L48Q Ca2+-sensitizing mutation
Dan D. Wang, I. M. Robertson, Monica X. Li, M. McCully +6 more
2012Biochemistry46 citations Open access
Semantic Scholar
Structural and functional insights into the cardiac Na⁺/H⁺ exchanger.
Brian L. Lee, B. Sykes, L. Fliegel
2013Journal of Molecular and Cellular Cardiology40 citations
Semantic Scholar
Structural and Functional Analysis of Transmembrane Segment VI of the NHE1 Isoform of the Na+/H+ Exchanger*
Jennifer Tzeng, Brian L. Lee, B. Sykes, L. Fliegel
2010Journal of Biological Chemistry40 citations Open access
Semantic Scholar
Formate can differentiate between hyperhomocysteinemia due to impaired remethylation and impaired transsulfuration.
S. Lamarre, A. Molloy, S. Reinke, B. Sykes +2 more
2012American Journal of Physiology. Endocrinology and Metabolism39 citations Open access
Semantic Scholar
Structure of trans-resveratrol in complex with the cardiac regulatory protein troponin C
Sandra E. Pineda-Sanabria, I. M. Robertson, B. Sykes
2011Biochemistry36 citations Open access
Semantic Scholar
Solution Structure of the Regulatory Domain of Human Cardiac Troponin C in Complex with the Switch Region of Cardiac Troponin I and W7: The Basis of W7 as an Inhibitor of Cardiac Muscle Contraction
Marta Oleszczuk, I. M. Robertson, Monica X. Li, B. Sykes
2010Journal of Molecular and Cellular Cardiology35 citations Open access
Semantic Scholar
A PagP fusion protein system for the expression of intrinsically disordered proteins in Escherichia coli.
P. Hwang, Jonathan S Pan, B. Sykes
2012Protein Expression and Purification33 citations
Semantic Scholar
Structures reveal details of small molecule binding to cardiac troponin
F. Cai, Monica X. Li, Sandra E. Pineda-Sanabria, Shorena Gelozia +4 more
2016Journal of Molecular and Cellular Cardiology32 citations Open access
Semantic Scholar
Computer-aided drug discovery approach finds calcium sensitizer of cardiac troponin
Steffen Lindert, Monica X. Li, B. Sykes, J. McCammon
2014Chemical Biology and Drug Design28 citations Open access
Semantic Scholar
A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS alleles
R. Mercer, N. Daude, L. Dorosh, Ze-Lin Fu +15 more
2018PLoS Pathogens25 citations Open access
Semantic Scholar
Solution Structure of a DNA Duplex Containing the Potent Anti-Poxvirus Agent Cidofovir
O. Julien, J. Beadle, Wendy C. Magee, S. Chatterjee +3 more
2011Journal of the American Chemical Society25 citations Open access
Semantic Scholar
Structural analysis of the Na+/H+ exchanger isoform 1 (NHE1) using the divide and conquer approach.
Brian L. Lee, B. Sykes, L. Fliegel
2011Biochemistry and cell biology = Biochimie et biologie cellulaire23 citations
Semantic Scholar
UBC9-dependent Association between Calnexin and Protein Tyrosine Phosphatase 1B (PTP1B) at the Endoplasmic Reticulum*
Dukgyu Lee, Allison Kraus, Daniel Prins, J. Groenendyk +8 more
2015Journal of Biological Chemistry22 citations Open access
Semantic Scholar
Metagenomic and metabolomic characterization of rabies encephalitis: new insights into the treatment of an ancient disease.
S. Reinke, L. Resch, F. Maingat, W. Branton +6 more
2013Journal of Infectious Diseases22 citations
Semantic Scholar
Relative and regional stabilities of the hamster, mouse, rabbit, and bovine prion proteins toward urea unfolding assessed by nuclear magnetic resonance and circular dichroism spectroscopies.
O. Julien, S. Chatterjee, T. Bjorndahl, B. Sweeting +7 more
2011Biochemistry22 citations
Semantic Scholar
The structural and functional effects of the familial hypertrophic cardiomyopathy-linked cardiac troponin C mutation, L29Q
I. M. Robertson, Ivanka R. Sevrieva, Monica X. Li, M. Irving +2 more
2015Journal of Molecular and Cellular Cardiology21 citations Open access
Semantic Scholar
Versatile cardiac troponin chimera for muscle protein structural biology and drug discovery.
Sandra E. Pineda-Sanabria, O. Julien, B. Sykes
2014ACS Chemical Biology16 citations
Semantic Scholar
Elucidation of Isoform-dependent pH Sensitivity of Troponin I by NMR Spectroscopy*
I. M. Robertson, P. Holmes, Monica X. Li, Sandra E. Pineda-Sanabria +2 more
2011Journal of Biological Chemistry16 citations Open access
Semantic Scholar
Visualizing the principal component of 1H,15N-HSQC NMR spectral changes that reflect protein structural or functional properties: application to troponin C
I. M. Robertson, Robert F. Boyko, B. Sykes
2011Journal of Biomolecular NMR16 citations
Semantic Scholar
Expression of Saccharomyces cerevisiae Sdh3p and Sdh4p Paralogs Results in Catalytically Active Succinate Dehydrogenase Isoenzymes*
Samuel S. W. Szeto, S. Reinke, K. S. Oyedotun, B. Sykes +1 more
2012Journal of Biological Chemistry15 citations Open access
Semantic Scholar
Probing the mechanism of cardiovascular drugs using a covalent levosimendan analog
Sandra E. Pineda-Sanabria, I. M. Robertson, Yin-Biao Sun, M. Irving +1 more
2016Journal of Molecular and Cellular Cardiology14 citations Open access
Semantic Scholar
Structural and functional analysis of the transmembrane segment pair VI and VII of the NHE1 isoform of the Na+/H+ exchanger.
C. Alves, Brian L. Lee, B. Sykes, L. Fliegel
2014Biochemistry13 citations
Semantic Scholar
Structural Basis of Tirasemtiv Activation of Fast Skeletal Muscle.
Monica X. Li, P. Mercier, J. Hartman, B. Sykes
2021Journal of Medicinal Chemistry12 citations
Semantic Scholar
Reversible Covalent Binding to Cardiac Troponin C by the Ca2+-Sensitizer Levosimendan.
I. M. Robertson, Sandra E. Pineda-Sanabria, Ziqian Yan, Thomas Kampourakis +3 more
2016Biochemistry12 citations
Semantic Scholar
Structural and Functional Analysis of Transmembrane Segment IV of the Salt Tolerance Protein Sod2*
Asad Ullah, Grant Kemp, Brian L. Lee, C. Alves +3 more
2013Journal of Biological Chemistry12 citations Open access
Semantic Scholar
Structural and functional analysis of critical amino acids in TMVI of the NHE1 isoform of the Na+/H+ exchanger.
Jennifer Tzeng, Brian L. Lee, B. Sykes, L. Fliegel
2011Biochimica et Biophysica Acta12 citations Open access
Semantic Scholar
Diverse residues of intracellular loop 5 of the Na+/H+ exchanger modulate proton sensing, expression, activity and targeting.
Ka-Yee Wong, R. McKay, Yong-Sheng Liu, K. Towle +6 more
2019Biochimica et Biophysica Acta - Biomembranes11 citations Open access
Semantic Scholar
Structural Changes Induced by the Binding of the Calcium Desensitizer W7 to Cardiac Troponin.
F. Cai, P. Hwang, B. Sykes
2018Biochemistry10 citations Open access
Semantic Scholar
Interaction between the regulatory domain of cardiac troponin C and the acidosis-resistant cardiac troponin I A162H.
Sandra E. Pineda-Sanabria, I. M. Robertson, Monica X. Li, B. Sykes
2013Cardiovascular Research10 citations Open access
Semantic Scholar
Characterization of a novel weak interaction between MUC1 and Src-SH3 using nuclear magnetic resonance spectroscopy.
Nirosha Gunasekara, B. Sykes, J. Hugh
2012Biochemical and Biophysical Research Communications - BBRC10 citations
Semantic Scholar
Structural and functional analysis of extracellular loop 4 of the Nhe1 isoform of the Na(+)/H(+) exchanger.
Brian L. Lee, Yong-Sheng Liu, Xiu-Ju J. Li, B. Sykes +1 more
2012Biochimica et Biophysica Acta10 citations Open access
Semantic Scholar
Correlating structure, dynamics, and function in transmembrane segment VII of the Na+/H+ exchanger isoform 1.
T. Reddy, Xiu-Ju J. Li, L. Fliegel, B. Sykes +1 more
2010Biochimica et Biophysica Acta10 citations Open access
Semantic Scholar
Reversible Covalent Reaction of Levosimendan with Cardiac Troponin C in Vitro and in Situ.
Brittney A. Klein, B. Reiz, I. M. Robertson, M. Irving +3 more
2018Biochemistry9 citations
Semantic Scholar
The calcium sensitizer drug MCI-154 binds the structural C-terminal domain of cardiac troponin C
Monica X. Li, Shorena Gelozia, G. I. Danmaliki, Yu-Rong Wen +5 more
2018Biochemistry and Biophysics Reports9 citations Open access
Semantic Scholar
Mass Incarceration and the Underground Economy in America
B. Sykes, A. Geller
20178 citations
Semantic Scholar
Thioimidate Bond Formation between Cardiac Troponin C and Nitrile-containing Compounds
Brittney A. Klein, I. M. Robertson, B. Reiz, Thomas Kampourakis +2 more
2019ACS Medicinal Chemistry Letters7 citations Open access
Semantic Scholar
Conformation of the critical pH sensitive region of troponin depends upon a single residue in troponin I.
I. M. Robertson, Sandra E. Pineda-Sanabria, P. Holmes, B. Sykes
2014Archives of Biochemistry and Biophysics6 citations
Semantic Scholar
Optimizing fluorine labelling for 19F solid-state NMR in oriented biological systems
I. M. Robertson, Brittney A. Klein, B. Sykes
2020Journal of Biomolecular NMR4 citations
Semantic Scholar
The Role of Electrostatics in the Mechanism of Cardiac Thin Filament Based Sensitizers.
F. Cai, I. M. Robertson, Thomas Kampourakis, Brittney A. Klein +1 more
2020ACS Chemical Biology4 citations Open access
Semantic Scholar
Feasibility of trifluoromethyl TROSY NMR at high magnetic fields
Brittney A. Klein, B. Sykes
2019Journal of Biomolecular NMR4 citations
Semantic Scholar
The carboxyl terminal segment of apolipoprotein A-V undergoes a lipid-induced conformational change
K. Mauldin, Brian L. Lee, Marta Oleszczuk, B. Sykes +1 more
2010Biochemistry4 citations Open access
Semantic Scholar
Metabolomic study of disease progression in scrapie prion infected mice; validation of a novel method for brain metabolite extraction
Ze-Lin Fu, P. Mercier, Ghazaleh Eskandari-Sedighi, Jing Yang +2 more
2020Metabolomics3 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

I. M. Robertson×15
Invite
I. M. Robertson — researcher profile on SciRah
Monica X. Li×10
Invite
Monica X. Li — researcher profile on SciRah
Sandra E. Pineda-Sanabria×9
Invite
Sandra E. Pineda-Sanabria — researcher profile on SciRah
L. Fliegel×9
Invite
L. Fliegel — researcher profile on SciRah

×8

Invite

Brian L. Lee — researcher profile on SciRah

Invite

P. Hwang — researcher profile on SciRah

Invite

S. Reinke — researcher profile on SciRah

Yin-Biao Sun×5

Invite

Yin-Biao Sun — researcher profile on SciRah

Brittney A. Klein×5

Invite

Brittney A. Klein — researcher profile on SciRah

Invite

F. Cai — researcher profile on SciRah

Invite

O. Julien — researcher profile on SciRah

Invite

M. Irving — researcher profile on SciRah