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Byron Brook · SciRah

Researcher profile · Semantic Scholar

Byron Brook

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Byron Brook — researcher profile on SciRah

h-index: 12
Works: 22
Citations: 523

Most-cited papers

BCG vaccination–induced emergency granulopoiesis provides rapid protection from neonatal sepsis
Byron Brook, Danny J. Harbeson, C. Shannon, Bing Cai +23 more
2020Science Translational Medicine123 citations Open access
Semantic Scholar
An aluminum hydroxide:CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor-binding domain vaccine in aged mice
E. Nanishi, F. Borriello, Timothy R. O’Meara, M. McGrath +42 more
2021Science Translational Medicine104 citations Open access
Semantic Scholar
Newborn susceptibility to infection vs. disease depends on complex in vivo interactions of host and pathogen
Byron Brook, Danny J. Harbeson, R. Ben Othman, D. Viemann +1 more
2017Seminars in Immunopathology44 citations
Semantic Scholar
Adjuvantation of a SARS-CoV-2 mRNA vaccine with controlled tissue-specific expression of an mRNA encoding IL-12p70
Byron Brook, Valerie Duval, S. Barman, Lauren Speciner +13 more
2024Science Translational Medicine43 citations
Semantic Scholar
Precision Vaccine Development: Cues From Natural Immunity
S. Barman, Dheeraj Soni, Byron Brook, E. Nanishi +1 more
2022Frontiers in Immunology33 citations Open access
Semantic Scholar
Development of a TLR7/8 agonist adjuvant formulation to overcome early life hyporesponsiveness to DTaP vaccination
David J. Dowling, S. Barman, Alyson J. Smith, F. Borriello +13 more
2022Scientific Reports23 citations Open access
Semantic Scholar
Human in vitro modeling of adjuvant formulations demonstrates enhancement of immune responses to SARS-CoV-2 antigen
Simon Doss-Gollin, Sanya Thomas, Byron Brook, Kimia Abedi +7 more
2023npj Vaccines21 citations Open access
Semantic Scholar
A Controlled Mouse Model for Neonatal Polymicrobial Sepsis.
Byron Brook, Nelly Amenyogbe, R. Ben Othman, Bing Cai +6 more
2019Journal of Visualized Experiments20 citations
Semantic Scholar
mRNA booster vaccination protects aged mice against the SARS-CoV-2 Omicron variant
E. Nanishi, M. McGrath, Timothy R. O’Meara, S. Barman +17 more
2022Communications Biology16 citations Open access
Semantic Scholar
A place for neutrophils in the beneficial pathogen-agnostic effects of the BCG vaccine
Byron Brook, F. Schaltz-Buchholzer, R. Ben Othman, T. Kollmann +1 more
2021Vaccine15 citations Open access
Semantic Scholar
Shaping neonatal immunization by tuning delivery of synergistic adjuvants via nanocarriers
S. Barman, F. Borriello, Byron Brook, Carlo Pietrasanta +12 more
2022bioRxiv13 citations Open access
Semantic Scholar
Robust health-score based survival prediction for a neonatal mouse model of polymicrobial sepsis
Byron Brook, Danny J. Harbeson, Nelly Amenyogbe, R. Ben Othman +2 more
2019PLoS ONE12 citations Open access
Semantic Scholar
Immunisation with the BCG and DTPw vaccines induces different programs of trained immunity in mice
N. Stevens, Marjolein van Wolfswinkel, Winnie Bao, F. Ryan +7 more
2021Vaccine11 citations
Semantic Scholar
Probiotic Studies in Neonatal Mice Using Gavage.
F. Francis, N. Varankovich, Byron Brook, Nelly Amenyogbe +9 more
2019Journal of Visualized Experiments10 citations Open access
Semantic Scholar
Alum:CpG adjuvant enables SARS-CoV-2 RBD-induced protection in aged mice and synergistic activation of human elder type 1 immunity
E. Nanishi, F. Borriello, Timothy R. O’Meara, M. McGrath +38 more
2021bioRxiv9 citations Open access
Semantic Scholar
The BNT162b2 mRNA vaccine demonstrates reduced age-associated TH1 support in vitro and in vivo
Byron Brook, A. Checkervarty, S. Barman, Cali Sweitzer +17 more
2024iScience8 citations Open access
Semantic Scholar
mRNA vaccines – miRNA-based controlled biodistribution and directed adjuvantation
Byron Brook, Morgan Goetz, Valerie Duval, Romain Micol +1 more
2025Trends in immunology6 citations Open access
Semantic Scholar
Discovery of a small molecule TLR3 agonist adjuvant
Branden Lee, Danica Dong, E. Nanishi, J. Awad +30 more
2025Nature Communications5 citations Open access
Semantic Scholar
The mRNA vaccine BNT162b2 demonstrates impaired TH1 immunogenicity in human elders in vitro and aged mice in vivo
Byron Brook, B. Fatou, A. Checkervarty, S. Barman +18 more
2022Research Square5 citations Open access
Semantic Scholar
Angiogenesis-associated pathways play critical roles in neonatal sepsis outcomes
Mario Fidanza, Julie Hibbert, E. Acton, Danny J. Harbeson +19 more
2024Scientific Reports4 citations Open access
Semantic Scholar
Induction of pBAD-ompA Fails to Enhance Conjugation in ompA-Deletion Mutant Escherichia coli Strains Containing the Plasmid
Byron Brook, Arella Wu
20131 citations
Semantic Scholar
BCG-induced nonspecific protection from neonatal sepsis
Byron Brook
20200 citations
Semantic Scholar

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David J. Dowling×12
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David J. Dowling — researcher profile on SciRah
E. Nanishi×10
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E. Nanishi — researcher profile on SciRah
S. Barman×9
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S. Barman — researcher profile on SciRah
O. Levy×8
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T. Kollmann — researcher profile on SciRah

S. V. van Haren×7

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Manisha Menon×7

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Danny J. Harbeson×6

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Danny J. Harbeson — researcher profile on SciRah

R. Ben Othman×6

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Nelly Amenyogbe×6

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Nelly Amenyogbe — researcher profile on SciRah

Timothy R. O’Meara×6

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F. Borriello×5

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F. Borriello — researcher profile on SciRah