Hiroko Kushiyama

Most-cited papers

1. Caspase-1 initiates apoptosis in the absence of gasdermin D

   K. Tsuchiya, Shinsuke Nakajima, S. Hosojima, Dinh Thi Nguyen +11 more

   2019Nature Communications447 citations Open access

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2. Vitamin B6 Prevents IL-1β Protein Production by Inhibiting NLRP3 Inflammasome Activation*

   Peipei Zhang, K. Tsuchiya, Takeshi Kinoshita, Hiroko Kushiyama +5 more

   2016Journal of Biological Chemistry125 citations Open access

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3. Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes.

   K. Tsuchiya, S. Hosojima, H. Hara, Hiroko Kushiyama +3 more

   2021Cell Reports119 citations Open access

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4. Pyroptotic cells externalize eat-me and release find-me signals and are efficiently engulfed by macrophages.

   Qiang Wang, R. Imamura, Kou Motani, Hiroko Kushiyama +2 more

   2013International Immunology109 citations Open access

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5. NLRP3 Mediates NF-κB Activation and Cytokine Induction in Microbially Induced and Sterile Inflammation

   Takeshi Kinoshita, R. Imamura, Hiroko Kushiyama, T. Suda

   2015PLoS ONE74 citations Open access

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6. Caspase-1 Protein Induces Apoptosis-associated Speck-like Protein Containing a Caspase Recruitment Domain (ASC)-mediated Necrosis Independently of Its Catalytic Activity*

   Kou Motani, Hiroko Kushiyama, R. Imamura, Takeshi Kinoshita +2 more

   2011Journal of Biological Chemistry55 citations Open access

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7. Caspase‐7 mediates caspase‐1‐induced apoptosis independently of Bid

   M. Mahib, S. Hosojima, Hiroko Kushiyama, Takeshi Kinoshita +3 more

   2020Microbiology and immunology33 citations Open access

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8. Activation of ASC induces apoptosis or necrosis, depending on the cell type, and causes tumor eradication

   Kou Motani, Kouji Kawase, R. Imamura, Takeshi Kinoshita +2 more

   2010Cancer Science27 citations Open access

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9. Gasdermin D Mediates the Maturation and Release of IL-1α Downstream of Inflammasomes

   K. Tsuchiya, S. Hosojima, Hiroko Kushiyama, M. Mahib +2 more

   20206 citations Open access

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10. Vitamin B6 suppresses NLRP3 inflammasome Vitamin B6 prevents IL-1β production by inhibiting NLRP3 inflammasome activation*

    Peipei Zhang, K. Tsuchiya, Takeshi Kinoshita, Hiroko Kushiyama +6 more

    20170 citations

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11. Inflammasome (PP-078)

    G. E. Pérez Figueroa, O. Ibañez, F. Vorraro, A. Galvan +38 more

    20100 citations

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12. Inflammasome (WS-078) Chairpersons: Shun'ichiro Taniguchi, Takashi Suda

    T. Ichinohe, A. Iwasaki, A. Dorhoi, G. Nouailles +46 more

    20100 citations

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