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K. Bortoluci · SciRah

Researcher profile · Semantic Scholar

K. Bortoluci

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K. Bortoluci — researcher profile on SciRah

h-index: 25
Works: 68
Citations: 8,651

Most-cited papers

Guidelines for the use and interpretation of assays for monitoring autophagy
D. Klionsky, F. C. Abdalla, H. Abeliovich, Robert T. Abraham +496 more
20124,979 citations Open access
Semantic Scholar
Two physically, functionally, and developmentally distinct peritoneal macrophage subsets
E. Ghosn, A. Cassado, G. Govoni, Takeshi Fukuhara +6 more
2010Proceedings of the National Academy of Sciences of the United States of America652 citations Open access
Semantic Scholar
Pattern Recognition Receptors and the Host Cell Death Molecular Machinery
G. Amarante-Mendes, S. Adjemian, L. M. Branco, Larissa C. Zanetti +2 more
2018Frontiers in Immunology628 citations Open access
Semantic Scholar
Inflammasome-derived IL-1β production induces nitric oxide–mediated resistance to Leishmania
Djalma S. Lima-Junior, Diego L. Costa, Vanessa Carregaro, L. D. Cunha +9 more
2013Nature Medicine368 citations
Semantic Scholar
Revisiting Mouse Peritoneal Macrophages: Heterogeneity, Development, and Function
Alexandra dos Anjos Cassado, M. D. D'Império Lima, K. Bortoluci
2015Frontiers in Immunology290 citations Open access
Semantic Scholar
Acetate coordinates neutrophil and ILC3 responses against C. difficile through FFAR2
J. Fachi, Cristiane Sécca, P. B. Rodrigues, F. C. D. de Mato +18 more
2019Journal of Experimental Medicine207 citations Open access
Semantic Scholar
Regulatory T Cells Accumulate in the Lung Allergic Inflammation and Efficiently Suppress T-Cell Proliferation but Not Th2 Cytokine Production
L. Faustino, D. Mucida, A. Keller, J. Demengeot +6 more
2011Clinical and Developmental Immunology161 citations Open access
Semantic Scholar
Control of infection by pyroptosis and autophagy: role of TLR and NLR
K. Bortoluci, R. Medzhitov
2010Cellular and Molecular Life Sciences144 citations
Semantic Scholar
Critical Role of ASC Inflammasomes and Bacterial Type IV Secretion System in Caspase-1 Activation and Host Innate Resistance to Brucella abortus Infection
M. Gomes, Priscila C. Campos, Fernanda S. Oliveira, P. P. Corsetti +4 more
2013Journal of Immunology117 citations Open access
Semantic Scholar
NLRP3 Controls Trypanosoma cruzi Infection through a Caspase-1-Dependent IL-1R-Independent NO Production
V. M. Gonçalves, K. Matteucci, C. Buzzo, Bruna H. Miollo +5 more
2013PLoS Neglected Tropical Diseases108 citations Open access
Semantic Scholar
Pulmonary Infection with Hypervirulent Mycobacteria Reveals a Crucial Role for the P2X7 Receptor in Aggressive Forms of Tuberculosis
E. P. Amaral, Simone C. M. Ribeiro, V. Lanes, F. M. Almeida +9 more
2014PLoS Pathogens88 citations Open access
Semantic Scholar
Emerging Concepts about NAIP/NLRC4 Inflammasomes
S. L. Lage, Carla Longo, L. M. Branco, Thaís Boccia da Costa +2 more
2014Frontiers in Immunology65 citations Open access
Semantic Scholar
Toll‐like receptor 4 agonists adsorbed to aluminium hydroxide adjuvant attenuate ovalbumin‐specific allergic airway disease: role of MyD88 adaptor molecule and interleukin‐12/interferon‐γ axis
J. Bortolatto, E. Borducchi, D. Rodriguez, A. Keller +9 more
2008Clinical and Experimental Allergy64 citations
Semantic Scholar
Inflammasome activation and IL-1 signaling during placental malaria induce poor pregnancy outcomes
A. S. Reis, R. Barboza, Oscar Murillo, André Barateiro +22 more
2020Science Advances62 citations Open access
Semantic Scholar
Cellular Renewal and Improvement of Local Cell Effector Activity in Peritoneal Cavity in Response to Infectious Stimuli
Alexandra dos Anjos Cassado, J. D. de Albuquerque, L. R. Sardinha, Carina de Lima Buzzo +6 more
2011PLoS ONE59 citations Open access
Semantic Scholar
Role of interplay between IL-4 and IFN-γ in the in regulating M1 macrophage polarization induced by Nattectin.
E. Ishizuka, M. J. Ferreira, Lidiane Zito Grund, E. Coutinho +5 more
2012International Immunopharmacology56 citations Open access
Semantic Scholar
Cytosolic flagellin-induced lysosomal pathway regulates inflammasome-dependent and -independent macrophage responses
S. L. Lage, C. Buzzo, E. P. Amaral, K. Matteucci +8 more
2013Proceedings of the National Academy of Sciences of the United States of America53 citations Open access
Semantic Scholar
A Novel Pathway for Inducible Nitric-oxide Synthase Activation through Inflammasomes*
C. Buzzo, J. Campopiano, L. Massis, S. L. Lage +7 more
2010Journal of Biological Chemistry52 citations Open access
Semantic Scholar
TLR4/MYD88-dependent, LPS-induced synthesis of PGE2 by macrophages or dendritic cells prevents anti-CD3-mediated CD95L upregulation in T cells
R. Weinlich, K. Bortoluci, C. F. Chehab, C. H. Serezani +4 more
2008Cell Death and Differentiation41 citations
Semantic Scholar
Annexin A1 Regulates NLRP3 Inflammasome Activation and Modifies Lipid Release Profile in Isolated Peritoneal Macrophages
J. Sanches, L. M. Branco, Gustavo Duarte, S. M. Oliani +3 more
2020Cells35 citations Open access
Semantic Scholar
Epigenetic regulation of nitric oxide synthase 2, inducible (Nos2) by NLRC4 inflammasomes involves PARP1 cleavage
Carina de Lima Buzzo, T. Medina, L. M. Branco, S. L. Lage +5 more
2017Scientific Reports33 citations Open access
Semantic Scholar
Infection by the Sylvio X10/4 clone of Trypanosoma cruzi: relevance of a low-virulence model of Chagas' disease.
C. Marinho, L. N. Nuñez-Apaza, K. Bortoluci, A. L. Bombeiro +7 more
2009Microbes and infection33 citations Open access
Semantic Scholar
Chagas Disease: Still Many Unsolved Issues
J. Álvarez, R. Fonseca, Henrique Borges da Silva, C. Marinho +4 more
2014Mediators of Inflammation31 citations Open access
Semantic Scholar
Caspase-8 and FADD: Where Cell Death and Inflammation Collide.
M. P. Amaral, K. Bortoluci
2020Immunity26 citations Open access
Semantic Scholar
Inflammatory effect of Bothropstoxin-I from the Bothrops jararacussu venom mediated by NLRP3 inflammasome involves ATP and P2X7 receptor.
P. R. Silva, D. S. de Lima, J. Luiz, N. Câmara +4 more
2021Clinical science25 citations Open access
Semantic Scholar
Drug Repurposing in Chagas Disease: Chloroquine Potentiates Benznidazole Activity against Trypanosoma cruzi In Vitro and In Vivo
R. Pandey, M. S. Nascimento, C. Franco, K. Bortoluci +12 more
2022Antimicrobial Agents and Chemotherapy24 citations Open access
Semantic Scholar
The global response to the COVID-19 pandemic: how have immunology societies contributed?
F. Osier, J. Ting, J. Fraser, B. Lambrecht +25 more
2020Nature reviews. Immunology23 citations Open access
Semantic Scholar
Frontline Science: Autophagy is a cell autonomous effector mechanism mediated by NLRP3 to control Trypanosoma cruzi infection
K. Matteucci, G. J. Pereira, R. Weinlich, K. Bortoluci
2019Journal of Leukocyte Biology20 citations
Semantic Scholar
Endostatin gene therapy inhibits intratumoral macrophage M2 polarization.
K. Foguer, Marina de Souza Braga, J. Peron, K. Bortoluci +1 more
2016Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie19 citations Open access
Semantic Scholar
Evaluation of pyroptosis in macrophages using cytosolic delivery of purified flagellin.
S. L. Lage, G. Amarante-Mendes, K. Bortoluci
2013Methods17 citations
Semantic Scholar
Role of Annexin A1 in NLRP3 Inflammasome Activation in Murine Neutrophils
J. Sanches, Rebeca D. Correia-Silva, Gustavo Duarte, A. M. A. P. Fernandes +6 more
2021Cells16 citations Open access
Semantic Scholar
Paradise revealed III: why so many ways to die? Apoptosis, necroptosis, pyroptosis, and beyond
M. P. Amaral, L. M. Branco, A. Strasser, V. Dixit +1 more
2020Cell Death and Differentiation15 citations Open access
Semantic Scholar
A Human Trypanosome Suppresses CD8+ T Cell Priming by Dendritic Cells through the Induction of Immune Regulatory CD4+ Foxp3+ T Cells
Jonatan Ersching, Alexandre S. Basso, Vera Lucia Garcia Kalich, K. Bortoluci +1 more
2016PLoS Pathogens15 citations Open access
Semantic Scholar
Three Main SCFAs Mitigate Lung Inflammation and Tissue Remodeling Nlrp3-Dependent in Murine HDM-Induced Neutrophilic Asthma
Barbara S S Tagé, M. Gonzatti, R. P. Vieira, Alexandre C. Keller +2 more
2024Inflammation14 citations
Semantic Scholar
Lysosomal cathepsins act in concert with Gasdermin-D during NAIP/NLRC4-dependent IL-1β secretion
L. M. Branco, M. P. Amaral, Henning Boekhoff, Ana Bernadette Figueiredo de Lima +5 more
2022Cell Death and Disease14 citations Open access
Semantic Scholar
The impairment in the NLRP3‐induced NO secretion renders astrocytes highly permissive to T. cruzi replication
Aline L. Pacheco, G. Vicentini, K. Matteucci, R. Ribeiro +2 more
2019Journal of Leukocyte Biology14 citations
Semantic Scholar
Pathogen-Induced Proapoptotic Phenotype and High CD95 (Fas) Expression Accompany a Suboptimal CD8+ T-Cell Response: Reversal by Adenoviral Vaccine
J. R. Vasconcelos, O. Bruna-Romero, A. Araújo, M. Dominguez +8 more
2012PLoS Pathogens14 citations Open access
Semantic Scholar
Control of infection by pyroptosis and autophagy: role of TLR and NLR
K. Bortoluci, R. Medzhitov
201014 citations
Semantic Scholar
Anti-IL-2 Treatment Impairs the Expansion of Treg Cell Population during Acute Malaria and Enhances the Th1 Cell Response at the Chronic Disease
C. A. Zago, K. Bortoluci, L. R. Sardinha, F. Pretel +8 more
2012PLoS ONE13 citations Open access
Semantic Scholar
Extracellular vesicles derived from head and neck squamous cells carcinoma inhibit NLRP3 inflammasomes
L. Bottino, Dorival Mendes Rodrigues-Junior, Ingrid S. de Farias, L. M. Branco +4 more
2021Current Research in Immunology10 citations Open access
Semantic Scholar
Rapamycin Improves the Response of Effector and Memory CD8+ T Cells Induced by Immunization With ASP2 of Trypanosoma cruzi
B. F. Moraschi, I. Noronha, C. Ferreira, L. M. Cariste +9 more
2021Frontiers in Cellular and Infection Microbiology9 citations Open access
Semantic Scholar
RIPK3 and Caspase-1/11 Are Necessary for Optimal Antigen-Specific CD8 T Cell Response Elicited by Genetically Modified Listeria monocytogenes
Aamir Rana, F. C. de Almeida, Henry A. Paico Montero, Maryanne M. Gonzales Carazas +3 more
2020Frontiers in Immunology9 citations Open access
Semantic Scholar
Lysicamine Reduces Protein Kinase B (AKT) Activation and Promotes Necrosis in Anaplastic Thyroid Cancer
M. T. Rodrigues, Ana Paula Picaro Michelli, Gustavo Felisola Caso, Paloma Ramos de Oliveira +11 more
2023Pharmaceuticals8 citations Open access
Semantic Scholar
Caspase‐1/11 controls Zika virus replication in astrocytes by inhibiting glycolytic metabolism
Ingrid S. de Farias, Guilherme Ribeiro, I. Noronha, V. Lucena +4 more
2025The FEBS Journal6 citations
Semantic Scholar
The impact of inflammatory and metabolic markers on depression, anxiety, and cognition after COVID-19: a narrative review
E. Diniz, F. Scorza, F. M. S. Rodrigues, C. D. de Mello +3 more
2023Trends in Psychiatry and Psychotherapy6 citations Open access
Semantic Scholar
NAIP/NLRC4 inflammasome participates in macrophage responses to Trypanosoma cruzi by a mechanism that relies on cathepsin-dependent caspase-1 cleavage
M. P. Amaral, Felipe Daniel Cardoso, Ingrid S. de Farias, R. Q. de Souza +3 more
2023Frontiers in Immunology6 citations Open access
Semantic Scholar
Concomitant Isolation of Primary Astrocytes and Microglia for Protozoa Parasite Infection.
Aline de Oliveira Lima Pacheco, M. P. Amaral, Ingrid S. de Farias, L. Bottino +1 more
2020Journal of Visualized Experiments5 citations
Semantic Scholar
OIP5 Expression Sensitize Glioblastoma Cells to Lomustine Treatment
Dorival Mendes Rodrigues-Junior, T. P. Biassi, V. Carlin, M. Buri +3 more
2018Journal of Molecular Neuroscience4 citations
Semantic Scholar
Immunity to protozoan parasite infection (PP-002)
M. Nakaya, H. Hara, M. Yamazaki, H. Yoshida +326 more
20103 citations
Semantic Scholar
Relationship among Toll-like receptors, β2 adrenergic receptor, and mitogen-activated protein kinases in regulating Il1b transcription.
F. M. de Melo, J. Maricato, B. M. Freire, R. Q. de Souza +7 more
2025Journal of Immunology2 citations
Semantic Scholar

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L. M. Branco×7
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