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M. Osuchowski · SciRah

Researcher profile · Semantic Scholar

M. Osuchowski

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M. Osuchowski — researcher profile on SciRah

h-index: 30
Works: 112
Citations: 5,007

Most-cited papers

The Pathogenesis of Sepsis
D. Stearns-Kurosawa, M. Osuchowski, Catherine Valentine, S. Kurosawa +1 more
2011Annual Review of Pathology804 citations Open access
Semantic Scholar
Circulating Cytokine/Inhibitor Profiles Reshape the Understanding of the SIRS/CARS Continuum in Sepsis and Predict Mortality1
M. Osuchowski, K. Welch, J. Siddiqui, D. Remick
2006Journal of Immunology559 citations Open access
Semantic Scholar
Sepsis: multiple abnormalities, heterogeneous responses, and evolving understanding.
K. Iskander, M. Osuchowski, D. Stearns-Kurosawa, S. Kurosawa +3 more
2013Physiological Reviews462 citations Open access
Semantic Scholar
The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity
M. Osuchowski, M. Winkler, Tomasz Skirecki, S. Cajander +30 more
2021The Lancet Respiratory Medicine392 citations Open access
Semantic Scholar
Current gaps in sepsis immunology: new opportunities for translational research.
I. Rubio, M. Osuchowski, M. Shankar-Hari, Tomasz Skirecki +26 more
2019Lancet. Infectious Diseases (Print)301 citations Open access
Semantic Scholar
Minimum quality threshold in pre-clinical sepsis studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis
M. Osuchowski, A. Ayala, S. Bahrami, M. Bauer +27 more
2018Intensive Care Medicine Experimental172 citations Open access
Semantic Scholar
Stratification is the key: Inflammatory biomarkers accurately direct immunomodulatory therapy in experimental sepsis*
M. Osuchowski, J. Connett, K. Welch, Jill I. Granger +1 more
2009Critical Care Medicine148 citations Open access
Semantic Scholar
ABANDON THE MOUSE RESEARCH SHIP? NOT JUST YET!
M. Osuchowski, D. Remick, J. Lederer, Charles H. Lang +23 more
2014Shock139 citations Open access
Semantic Scholar
SEPSIS CHRONICALLY IN MARS: SYSTEMIC CYTOKINE RESPONSES ARE ALWAYS MIXED REGARDLESS OF THE OUTCOME, MAGNITUDE OR PHASE OF SEPSIS
M. Osuchowski, Florin Craciun, K. Weixelbaumer, Elizabeth R. Duffy +1 more
2012Journal of Immunology100 citations Open access
Semantic Scholar
Chronic Sepsis Mortality Characterized by an Individualized Inflammatory Response1
M. Osuchowski, K. Welch, Huan Yang, J. Siddiqui +1 more
2007Journal of Immunology92 citations Open access
Semantic Scholar
CECAL LIGATION AND PUNCTURE INDUCED MURINE SEPSIS DOES NOT CAUSE LUNG INJURY
K. Iskander, Florin Craciun, David M. Stepien, Elizabeth R. Duffy +5 more
2013Critical Care Medicine75 citations Open access
Semantic Scholar
Protective role of peroxisome proliferator-activated receptor-β/δ in septic shock.
A. Kapoor, Y. Shintani, M. Collino, M. Osuchowski +13 more
2010American Journal of Respiratory and Critical Care Medicine72 citations Open access
Semantic Scholar
PART II: MINIMUM QUALITY THRESHOLD IN PRE-CLINICAL SEPSIS STUDIES (MQTiPSS) FOR TYPES OF INFECTIONS AND ORGAN DYSFUNCTION ENDPOINTS.
C. Libert, A. Ayala, M. Bauer, J. Cavaillon +7 more
2019Shock64 citations Open access
Semantic Scholar
Relationship between Age/Gender-Induced Survival Changes and the Magnitude of Inflammatory Activation and Organ Dysfunction in Post-Traumatic Sepsis
S. Drechsler, K. Weixelbaumer, P. Raeven, M. Jafarmadar +4 more
2012PLoS ONE59 citations Open access
Semantic Scholar
Premise for Standardized Sepsis Models
D. Remick, A. Ayala, I. Chaudry, C. Coopersmith +4 more
2019Shock51 citations Open access
Semantic Scholar
Part III: Minimum Quality Threshold in Preclinical Sepsis Studies (MQTiPSS) for Fluid Resuscitation and Antimicrobial Therapy Endpoints.
J. Hellman, S. Bahrami, M. Boros, I. Chaudry +7 more
2019Shock50 citations Open access
Semantic Scholar
Influence of HIP pressure on tensile properties of a 14Cr ODS ferritic steel
Z. Oksiuta, A. Oziȩbło, K. Perkowski, M. Osuchowski +1 more
201448 citations
Semantic Scholar
Minimum Quality Threshold in Pre-Clinical Sepsis Studies (Mqtipss): An International Expert Consensus Initiative for Improvement of Animal Modeling in Sepsis
M. Osuchowski, A. Ayala, S. Bahrami, M. Bauer +27 more
2018Shock47 citations Open access
Semantic Scholar
SARS-CoV-2/COVID-19: Evolving Reality, Global Response, Knowledge Gaps, and Opportunities
M. Osuchowski, F. Aletti, J. Cavaillon, S. Flohé +6 more
2020Shock42 citations Open access
Semantic Scholar
Alterations in Regional Brain Neurotransmitters by Silymarin, a Natural Antioxidant Flavonoid Mixture, in BALB/c Mice
M. Osuchowski, V. Johnson, Quan-Ren He, Raghubir P. Sharma
200441 citations Open access
Semantic Scholar
Mitochondria-Targeted Antioxidants SkQ1 and MitoTEMPO Failed to Exert a Long-Term Beneficial Effect in Murine Polymicrobial Sepsis
P. Rademann, A. Weidinger, S. Drechsler, A. Meszaros +14 more
2017Oxidative Medicine and Cellular Longevity40 citations Open access
Semantic Scholar
Why do they die? Comparison of selected aspects of organ injury and dysfunction in mice surviving and dying in acute abdominal sepsis
S. Drechsler, K. Weixelbaumer, A. Weidinger, P. Raeven +7 more
2015Intensive Care Medicine Experimental40 citations Open access
Semantic Scholar
Fumonisin B1-induced neurodegeneration in mice after intracerebroventricular infusion is concurrent with disruption of sphingolipid metabolism and activation of proinflammatory signaling.
M. Osuchowski, G. Edwards, Raghubir P. Sharma
2005Neurotoxicology40 citations
Semantic Scholar
Sequential ELISA to profile multiple cytokines from small volumes.
M. Osuchowski, J. Siddiqui, Shannon Copeland, D. Remick
2005JIM - Journal of Immunological Methods38 citations
Semantic Scholar
Fumonisin B1 induces necrotic cell death in BV-2 cells and murine cultured astrocytes and is antiproliferative in BV-2 cells while N2A cells and primary cortical neurons are resistant.
M. Osuchowski, Raghubir P. Sharma
2005Neurotoxicology38 citations
Semantic Scholar
REPETITIVE LOW-VOLUME BLOOD SAMPLING METHOD AS A FEASIBLE MONITORING TOOL IN A MOUSE MODEL OF SEPSIS
K. Weixelbaumer, P. Raeven, H. Redl, M. van Griensven +2 more
2010Shock35 citations Open access
Semantic Scholar
How sepsis parallels and differs from COVID-19
A. Herminghaus, M. Osuchowski
2022EBioMedicine31 citations Open access
Semantic Scholar
UNTREATED TYPE 1 DIABETES INCREASES SEPSIS-INDUCED MORTALITY WITHOUT INDUCING A PRE-LETHAL CYTOKINE RESPONSE
M. Osuchowski, Florin Craciun, E. Schuller, C. Sima +2 more
2010Shock28 citations Open access
Semantic Scholar
NONINVASIVE MODEL OF SCIATIC NERVE CONDUCTION IN HEALTHY AND SEPTIC MICE: RELIABILITY AND NORMATIVE DATA
M. Osuchowski, J. W. Teener, D. Remick
2009Muscle and Nerve27 citations Open access
Semantic Scholar
Disruption of sphingolipid homeostasis by myriocin, a mycotoxin, reduces thymic and splenic T-lymphocyte populations.
V. Johnson, Quan-Ren He, M. Osuchowski, Raghubir P. Sharma
2004Toxicology26 citations
Semantic Scholar
Inhibition of Serine Palmitoyltransferase by Myriocin, a Natural Mycotoxin, Causes Induction of C-Myc in Mouse Liver
Quan-Ren He, V. Johnson, M. Osuchowski, Raghubir P. Sharma
2004Mycopathologia25 citations
Semantic Scholar
Myriocin, a serine palmitoyltransferase inhibitor, alters regional brain neurotransmitter levels without concurrent inhibition of the brain sphingolipid biosynthesis in mice.
M. Osuchowski, V. Johnson, Quan-Ren He, Raghubir P. Sharma
2004Toxicology Letters24 citations
Semantic Scholar
Bridging animal and clinical research during SARS-CoV-2 pandemic: A new-old challenge
M. Winkler, Tomasz Skirecki, F. Brunkhorst, S. Cajander +19 more
2021EBioMedicine23 citations Open access
Semantic Scholar
Cecal Ligation and Puncture.
S. Drechsler, M. Osuchowski
2021Methods in molecular biology23 citations
Semantic Scholar
Tissue reactions to polyethylene glycol and glutaraldehyde-based surgical sealants in a rabbit aorta model
P. Slezak, A. Klang, James C. Ferguson, X. Monforte +7 more
2020Journal of Biomaterials Applications23 citations Open access
Semantic Scholar
The Fluctuations of Leukocytes and Circulating Cytokines in Septic Humanized Mice Vary With Outcome
Tomasz Skirecki, S. Drechsler, G. Hoser, M. Jafarmadar +4 more
2019Frontiers in Immunology22 citations Open access
Semantic Scholar
The repetitive use of samples to measure multiple cytokines: the sequential ELISA.
M. Osuchowski, D. Remick
2006Methods22 citations
Semantic Scholar
Microstructure and thermal properties of mechanically alloyed W-1%TiC powder consolidated via two-step HIPping
Z. Oksiuta, K. Perkowski, M. Osuchowski, M. Zalewska +1 more
201821 citations
Semantic Scholar
Sepsis-3 on the block: what does it mean for pre-clinical sepsis modeling?
M. Osuchowski, C. Thiemermann, D. Remick
2017Shock21 citations Open access
Semantic Scholar
The thermal shock resistance of Y2O3 ceramics
M. Boniecki, Zdzisław Librant, W. Wesołowski, M. Gizowska +4 more
201621 citations
Semantic Scholar
Endotoxin exposure alters brain and liver effects of fumonisin B1 in BALB/c mice: implication of blood brain barrier.
M. Osuchowski, Quan-Ren He, Raghubir P. Sharma
2005Food and Chemical Toxicology21 citations
Semantic Scholar
Compartment-specific expression of plasminogen activator inhibitor-1 correlates with severity/outcome of murine polymicrobial sepsis.
P. Raeven, G. Feichtinger, K. Weixelbaumer, Simone Atzenhofer +4 more
2012Thrombosis Research20 citations
Semantic Scholar
COVID-19 and earlier pandemics, sepsis, and vaccines: A historical perspective
J. Cavaillon, M. Osuchowski
2021Journal of Intensive Medicine19 citations Open access
Semantic Scholar
Estrus Cycle Status Defined by Vaginal Cytology Does Not Correspond to Fluctuations of Circulating Estrogens in Female Mice
K. Weixelbaumer, S. Drechsler, Paul Wehrenpfennig, Anna Khadem +4 more
2014Shock19 citations Open access
Semantic Scholar
Impact of Idarucizumab and Andexanet Alfa on DOAC Plasma Concentration and ClotPro® Clotting Time: An Ex Vivo Spiking Study in A Cohort of Trauma Patients
D. Oberladstätter, C. Schlimp, Johannes Zipperle, M. Osuchowski +3 more
2021Journal of Clinical Medicine18 citations Open access
Semantic Scholar
Experimentally Approaching the ICU: Monitoring Outcome-Based Responses in the Two-Hit Mouse Model of Posttraumatic Sepsis
S. Drechsler, K. Weixelbaumer, H. Redl, M. van Griensven +2 more
2011Journal of Biomedicine and Biotechnology18 citations Open access
Semantic Scholar
Modelling physical resilience in ageing mice
M. Schosserer, G. Banks, S. Doğan, P. Dungel +9 more
2018Mechanisms of Ageing and Development17 citations Open access
Semantic Scholar
Contamination of wounds with fecal bacteria in immuno-suppressed mice
Lisa Karner, S. Drechsler, Magdalena Metzger, P. Slezak +7 more
2020Scientific Reports16 citations Open access
Semantic Scholar
Role of DOAC plasma concentration on perioperative blood loss and transfusion requirements in patients with hip fractures
H. Hofer, D. Oberladstätter, C. Schlimp, W. Voelckel +5 more
2022European Journal of Trauma and Emergency Surgery15 citations
Semantic Scholar
Systemic inhibition and liver‐specific over‐expression of PAI‐1 failed to improve survival in all‐inclusive populations or homogenous cohorts of CLP mice
P. Raeven, S. Drechsler, K. Weixelbaumer, D. Bastelica +8 more
2014Journal of Thrombosis and Haemostasis14 citations Open access
Semantic Scholar

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D. Remick×18
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D. Remick — researcher profile on SciRah
S. Bahrami×13
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S. Drechsler×11
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H. Redl×9
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J. Cavaillon — researcher profile on SciRah

K. Weixelbaumer×8

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K. Weixelbaumer — researcher profile on SciRah

Raghubir P. Sharma×7

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Raghubir P. Sharma — researcher profile on SciRah

Tomasz Skirecki×5

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I. Chaudry — researcher profile on SciRah

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