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L. Lacroix · SciRah

Researcher profile · Semantic Scholar

L. Lacroix

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L. Lacroix — researcher profile on SciRah

h-index: 40
Works: 74
Citations: 8,539

Most-cited papers

Structure of the human telomere in K+ solution: an intramolecular (3 + 1) G-quadruplex scaffold.
K. Luu, A. Phan, V. Kuryavyi, L. Lacroix +1 more
2006Journal of the American Chemical Society786 citations Open access
Semantic Scholar
Analysis of Thermal Melting Curves
J. Mergny, L. Lacroix
2003Oligonucleotides731 citations
Semantic Scholar
Following G‐quartet formation by UV‐spectroscopy
J. Mergny, A. Phan, L. Lacroix
1998FEBS Letters640 citations Open access
Semantic Scholar
Re-evaluation of G-quadruplex propensity with G4Hunter
Amina Bedrat, L. Lacroix, J. Mergny
2016Nucleic Acids Research604 citations Open access
Semantic Scholar
Targeting telomeres and telomerase.
A. de Cian, L. Lacroix, Céline Douarre, Nassima Temime-Smaali +3 more
2008Biochimie557 citations
Semantic Scholar
Thermal difference spectra: a specific signature for nucleic acid structures
J. Mergny, Jing Li, L. Lacroix, S. Amrane +1 more
2005Nucleic Acids Research439 citations Open access
Semantic Scholar
Fluorescence-based melting assays for studying quadruplex ligands.
A. de Cian, L. Guittat, M. Kaiser, B. Saccà +6 more
2007Methods346 citations
Semantic Scholar
Kinetics of tetramolecular quadruplexes
J. Mergny, A. de Cian, Amar Ghelab, B. Saccà +1 more
2005Nucleic Acids Research279 citations Open access
Semantic Scholar
Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action
A. de Cian, Gaël Cristofari, P. Reichenbach, E. D. de Lemos +6 more
2007Proceedings of the National Academy of Sciences of the United States of America261 citations Open access
Semantic Scholar
Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay
J. Mergny, L. Lacroix, M. Teulade‐Fichou, C. Hounsou +8 more
2001Proceedings of the National Academy of Sciences of the United States of America258 citations Open access
Semantic Scholar
Intramolecular Folding of Pyrimidine Oligodeoxynucleotides into an i-DNA Motif
J. Mergny, L. Lacroix, Xiao-Gang Han, J. Leroy +1 more
1995252 citations
Semantic Scholar
The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotides
B. Saccà, L. Lacroix, J. Mergny
2005Nucleic Acids Research246 citations Open access
Semantic Scholar
Telomerase downregulation induced by the G-quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing.
D. Gomez, Thibault Lemarteleur, L. Lacroix, P. Mailliet +2 more
2004Nucleic Acids Research226 citations Open access
Semantic Scholar
Guanines are a quartet's best friend: impact of base substitutions on the kinetics and stability of tetramolecular quadruplexes
Julien Gros, F. Rosu, S. Amrane, A. de Cian +3 more
2007Nucleic Acids Research184 citations Open access
Semantic Scholar
Involvement of G-quadruplex regions in mammalian replication origin activity
Paulina Prorok, Marie Artufel, Antoine Aze, P. Coulombe +10 more
2019Nature Communications173 citations Open access
Semantic Scholar
UV Melting of G‐Quadruplexes
J. Mergny, L. Lacroix
2009Current Protocols in Nucleic Acid Chemistry173 citations
Semantic Scholar
Coexistence of two distinct G-quadruplex conformations in the hTERT promoter.
K. W. Lim, L. Lacroix, D.J.E. Yue, Joefina Kim Cheow Lim +2 more
2010Journal of the American Chemical Society165 citations
Semantic Scholar
DNA nanomachines and nanostructures involving quadruplexes.
P. Alberti, A. Bourdoncle, B. Saccà, L. Lacroix +1 more
2006Organic and biomolecular chemistry135 citations
Semantic Scholar
Sequence variant (CTAGGG)n in the human telomere favors a G-quadruplex structure containing a G·C·G·C tetrad
K. W. Lim, P. Alberti, A. Guédin, L. Lacroix +4 more
2009Nucleic Acids Research134 citations Open access
Semantic Scholar
A metal-mediated conformational switch controls G-quadruplex binding affinity.
D. Monchaud, Peng Yang, L. Lacroix, M. Teulade‐Fichou +1 more
2008Angewandte Chemie133 citations
Semantic Scholar
Selective interaction of ethidium derivatives with quadruplexes: an equilibrium dialysis and electrospray ionization mass spectrometry analysis.
F. Rosu, E. De Pauw, L. Guittat, P. Alberti +4 more
2003Biochemistry109 citations
Semantic Scholar
Chromatin Immunoprecipitation Indirect Peaks Highlight Long-Range Interactions of Insulator Proteins and Pol II Pausing
Jun Liang, L. Lacroix, Adrien Gamot, Suresh Cuddapah +14 more
2014Molecules and Cells108 citations Open access
Semantic Scholar
Sequence effects in single-base loops for quadruplexes.
A. Guédin, A. de Cian, Julien Gros, L. Lacroix +1 more
2008Biochimie103 citations
Semantic Scholar
Identification of two human nuclear proteins that recognise the cytosine-rich strand of human telomeres in vitro.
L. Lacroix, Hélène Liénard, E. Labourier, M. Djavaheri-Mergny +5 more
2000Nucleic Acids Research102 citations Open access
Semantic Scholar
Quadruplex-based molecular beacons as tunable DNA probes.
A. Bourdoncle, A. E. Torres, C. Gosse, L. Lacroix +4 more
2006Journal of the American Chemical Society96 citations
Semantic Scholar
Kinetics and thermodynamics of i-DNA formation: phosphodiester versus modified oligodeoxynucleotides.
J. Mergny, L. Lacroix
1998Nucleic Acids Research87 citations Open access
Semantic Scholar
FORK-seq: replication landscape of the Saccharomyces cerevisiae genome by nanopore sequencing
M. Hennion, J. Arbona, L. Lacroix, C. Cruaud +9 more
2020Genome Biology69 citations Open access
Semantic Scholar
G4access identifies G-quadruplexes and their associations with open chromatin and imprinting control regions
C. Esnault, Talha Magat, Amal Zine El Aabidine, Encar García-Oliver +11 more
2023Nature Genetics67 citations Open access
Semantic Scholar
G‐Quadruplex Formation Interferes with P1 Helix Formation in the RNA Component of Telomerase hTERC
Julien Gros, A. Guédin, J. Mergny, L. Lacroix
2008ChemBioChem66 citations
Semantic Scholar
Thermal and pH stabilities of i-DNA: confronting in vitro experiments with models and in-cell NMR data.
Mingpan Cheng, De-Hui Qiu, Liezel Tamon, Eva Ištvánková +10 more
2021Angewandte Chemie63 citations Open access
Semantic Scholar
Inability of RNA to form the i-motif: implications for triplex formation.
L. Lacroix, J. Mergny, Jean-Louis Leroy, Claude Hélène
1996Biochemistry63 citations
Semantic Scholar
Resistance to the Short Term Antiproliferative Activity of the G-quadruplex Ligand 12459 Is Associated with Telomerase Overexpression and Telomere Capping Alteration*
D. Gomez, N. Aouali, A. Londoño-Vallejo, L. Lacroix +9 more
2003Journal of Biological Chemistry62 citations Open access
Semantic Scholar
New Insights on the Mechanism of Quinoline-based DNA Methyltransferase Inhibitors
Christina Gros, L. Fleury, V. Nahoum, C. Faux +12 more
2014Journal of Biological Chemistry59 citations Open access
Semantic Scholar
Rational Design of Bisubstrate-Type Analogues as Inhibitors of DNA Methyltransferases in Cancer Cells.
L. Halby, Yoann Menon, Elodie Rilova, Dany Pechalrieu +13 more
2017Journal of Medicinal Chemistry51 citations Open access
Semantic Scholar
Energetics of strand-displacement reactions in triple helices: a spectroscopic study.
Martin Mills, Paola B. Arimondo, L. Lacroix, T. Garestier +3 more
1999Journal of Molecular Biology51 citations
Semantic Scholar
Unusual DNA conformations: implications for telomeres.
Martin Mills, L. Lacroix, P. Arimondo, J. Leroy +3 more
2002Current Medicinal Chemistry - Anti-Cancer Agents50 citations
Semantic Scholar
Thermal melting studies of ligand DNA interactions.
A. Guédin, L. Lacroix, J. Mergny
2010Methods in molecular biology48 citations
Semantic Scholar
Guidelines for G-quadruplexes: I. In vitro characterization.
Yu-jun Luo, A. Granzhan, J. Marquevielle, Anne Cucchiarini +4 more
2022Biochimie47 citations Open access
Semantic Scholar
Triplex formation by oligonucleotides containing 5-(1-propynyl)-2'-deoxyuridine: decreased magnesium dependence and improved intracellular gene targeting.
L. Lacroix, J. Lacoste, James F. Reddoch, Jean-Louis Mergny +4 more
1999Biochemistry44 citations
Semantic Scholar
Genome-wide mapping of individual replication fork velocities using nanopore sequencing
Bertrand Theulot, L. Lacroix, J. Arbona, G. Millot +10 more
2022Nature Communications41 citations Open access
Semantic Scholar
Chemical modification of the third strand: differential effects on purine and pyrimidine triple helix formation.
Martin Mills, P. Arimondo, L. Lacroix, T. Garestier +2 more
2002Biochemistry37 citations
Semantic Scholar
8-Amino guanine accelerates tetramolecular G-quadruplex formation.
Julien Gros, A. Aviñó, J. López de la Osa, C. González +5 more
2008Chemical Communications36 citations Open access
Semantic Scholar
Fluorescence-based duplex–quadruplex competition test to screen for telomerase RNA quadruplex ligands
L. Lacroix, Aurélie Séosse, J. Mergny
2010Nucleic Acids Research35 citations Open access
Semantic Scholar
Genome wide distribution of G-quadruplexes and their impact on gene expression in malaria parasites
Elodie Gazanion, L. Lacroix, P. Alberti, Pratima Gurung +5 more
2020PLoS Genetics33 citations Open access
Semantic Scholar
Pyrimidine morpholino oligonucleotides form a stable triple helix in the absence of magnesium ions.
L. Lacroix, Paola B. Arimondo, M. Takasugi, Claude Hélène +1 more
2000Biochemical and Biophysical Research Communications - BBRC32 citations
Semantic Scholar
Human ORC/MCM density is low in active genes and correlates with replication time but does not delimit initiation zones
N. Kirstein, Alexander Buschle, Xia Wu, S. Krebs +8 more
2021eLife31 citations Open access
Semantic Scholar
Targeting human telomerase for cancer therapeutics
L. Guittat, P. Alberti, D. Gomez, A. de Cian +12 more
2004Cytotechnology (Dordrecht)29 citations Open access
Semantic Scholar
Nucleic acids as targets for antitelomerase agents.
P. Alberti, L. Lacroix, L. Guittat, C. Héléne +1 more
2003Mini-Reviews in Medical Chemistry29 citations
Semantic Scholar
Design of antisense and triplex-forming oligonucleotides.
Jean-Christophe François, J. Lacoste, L. Lacroix, J. Mergny
2000Methods in Enzymology24 citations
Semantic Scholar
Quadruplexes in ‘Dicty’: crystal structure of a four-quartet G-quadruplex formed by G-rich motif found in the Dictyostelium discoideum genome
A. Guédin, Linda Yingqi Lin, S. Armane, L. Lacroix +3 more
2018Nucleic Acids Research22 citations Open access
Semantic Scholar

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