S. Hoffmann

Most-cited papers

1. Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition.

   R. Goldbach-Mansky, N. J. Dailey, S. Canna, A. Gelabert +36 more

   2006New England Journal of Medicine832 citations Open access

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2. Immunocompetent T‐Cells with a Memory‐Like Phenotype are the Dominant Cell Type Following Antibody‐Mediated T‐Cell Depletion

   J. Pearl, J. Parris, D. Hale, S. Hoffmann +6 more

   2005American Journal of Transplantation483 citations Open access

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3. RESULTS FROM A HUMAN RENAL ALLOGRAFT TOLERANCE TRIAL EVALUATING THE HUMANIZED CD52‐SPECIFIC MONOCLONAL ANTIBODY ALEMTUZUMAB (CAMPATH‐1H)

   Allan D. Kirk, D. Hale, R. Mannon, D. E. Kleiner +6 more

   2003Transplantation441 citations Open access

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4. ASSOCIATION OF CYTOKINE POLYMORPHIC INHERITANCE AND IN VITRO CYTOKINE PRODUCTION IN ANTI-CD3/CD28-STIMULATED PERIPHERAL BLOOD LYMPHOCYTES1

   S. Hoffmann, E. Stanley, E. Cox, N. Craighead +5 more

   2001Transplantation361 citations Open access

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5. Ethnicity Greatly Influences Cytokine Gene Polymorphism Distribution

   S. Hoffmann, E. Stanley, E. Cox, B. Dimercurio +4 more

   2002American Journal of Transplantation348 citations Open access

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6. Oligonucleotide Microarray Analysis of Intact Human Pancreatic Islets: Identification of Glucose-Responsive Genes and a Highly Regulated TGFβ Signaling Pathway

   Anath Shalev, C. Pise-Masison, M. Radonovich, S. Hoffmann +3 more

   2002230 citations

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7. Cd40 Ligand (Cd154) Triggers a Short-Term Cd4+ T Cell Activation Response That Results in Secretion of Immunomodulatory Cytokines and Apoptosis

   P. Blair, J. Riley, D. Harlan, R. Abe +7 more

   2000Journal of Experimental Medicine230 citations Open access

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8. Cytokine polymorphic analyses indicate ethnic differences in the allelic distribution of interleukin-2 and interleukin-6.

   E. Cox, S. Hoffmann, B. Dimercurio, R. Wesley +3 more

   2001Transplantation178 citations Open access

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9. Development and Evaluation of a Multiplexed Mass Spectrometry-Based Assay for Measuring Candidate Peptide Biomarkers in Alzheimer’s Disease Neuroimaging Initiative (ADNI) CSF

   Daniel S. Spellman, Kristin R. Wildsmith, Lee Honigberg, M. Tuefferd +10 more

   2015PROTEOMICS - Clinical Applications151 citations Open access

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10. Functionally Significant Renal Allograft Rejection Is Defined by Transcriptional Criteria

    S. Hoffmann, D. Hale, D. E. Kleiner, R. Mannon +6 more

    2005American Journal of Transplantation136 citations Open access

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11. Results from a Human Renal Allograft Tolerance Trial Evaluating T-Cell Depletion with Alemtuzumab Combined with Deoxyspergualin

    A. Kirk, R. Mannon, D. Kleiner, J. Swanson +7 more

    2005Transplantation122 citations Open access

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12. Resistin is expressed in pancreatic islets.

    Alexandra H. Minn, N. Patterson, S. Pack, S. Hoffmann +4 more

    2003Biochemical and Biophysical Research Communications - BBRC108 citations

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13. Molecular and immunohistochemical characterization of the onset and resolution of human renal allograft ischemia-reperfusion injury

    S. Hoffmann, Robert L. Kampen, Shashi Amur, M. Sharaf +7 more

    2002Transplantation100 citations Open access

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14. Donor genomics influence graft events: the effect of donor polymorphisms on acute rejection and chronic allograft nephropathy.

    S. Hoffmann, Jenny L. Park, L. M. Jacobson, R. Muehrer +7 more

    2004Kidney International78 citations Open access

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15. What evidence do we need for biomarker qualification?

    C. Leptak, J. Menetski, J. Wagner, J. Aubrecht +11 more

    2017Science Translational Medicine75 citations

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16. A proinsulin gene splice variant with increased translation efficiency is expressed in human pancreatic islets.

    Anath Shalev, P. Blair, S. Hoffmann, B. Hirshberg +2 more

    2002Endocrinology68 citations Open access

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17. The Foundation for the National Institutes of Health Biomarkers Consortium: Past Accomplishments and New Strategic Direction

    J. Menetski, S. Hoffmann, Stephanie S. Cush, Tania Nayak Kamphaus +3 more

    2019Clinical pharmacology and therapy48 citations Open access

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18. Disruption of CD40/CD40-Ligand Interactions in a Retinal Autoimmunity Model Results in Protection without Tolerance

    Lee M. Bagenstose, R. K. Agarwal, P. Silver, D. Harlan +4 more

    2005Journal of Immunology41 citations Open access

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19. Nitroglycerin reperfusion reduces ischemia-reperfusion injury in non-heart-beating donor lungs.

    T. Egan, S. Hoffmann, M. Sevala, J. Sadoff +1 more

    2006The Journal of Heart and Lung Transplantation38 citations

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20. Developing Outcomes Assessments as Endpoints for Registrational Clinical Trials of Antibacterial Drugs: 2015 Update From the Biomarkers Consortium of the Foundation for the National Institutes of Health.

    G. Talbot, J. Powers, S. Hoffmann

    2016Clinical Infectious Diseases35 citations Open access

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21. Insulinomas and expression of an insulin splice variant.

    Alexandra H. Minn, M. Kayton, D. Lorang, S. Hoffmann +3 more

    2004The Lancet34 citations

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22. Remote digital monitoring in clinical trials in the time of COVID-19

    J. Goldsack, E. Izmailova, J. Menetski, S. Hoffmann +2 more

    2020Nature reviews. Drug discovery27 citations

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23. Remote Digital Monitoring for Medical Product Development

    E. Izmailova, J. Wagner, N. Ammour, N. Amondikar +39 more

    2020Clinical and Translational Science26 citations Open access

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24. Reduced ischemia-reperfusion injury with rolipram in rat cadaver lung donors: effect of cyclic adenosine monophosphate.

    Mark S. Bleiweis, David R. Jones, S. Hoffmann, Randy M. Becker +1 more

    1999Annals of Thoracic Surgery26 citations

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25. Immune profiling: molecular monitoring in renal transplantation.

    S. Hoffmann, J. Pearl, P. Blair, A. Kirk

    2003Frontiers in Bioscience25 citations Open access

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26. Lung retrieval from non-heart beating cadavers with the use of a rat lung transplant model.

    A. Kiser, Paola Ciriaco, S. Hoffmann, Thomas Egan

    2001Journal of Thoracic and Cardiovascular Surgery25 citations Open access

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27. When does the lung die? Kfc, cell viability, and adenine nucleotide changes in the circulation-arrested rat lung.

    David R. Jones, Randy M. Becker, S. Hoffmann, J. Lemasters +1 more

    1997Journal of applied physiology23 citations

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28. Maintenance of cAMP in non-heart-beating donor lungs reduces ischemia-reperfusion injury.

    S. Hoffmann, Mark S. Bleiweis, David R. Jones, H. Paik +2 more

    2001American Journal of Respiratory and Critical Care Medicine21 citations

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29. Biomarkers of Crohn's Disease to Support the Development of New Therapeutic Interventions.

    A. C. Porter, J. Aubrecht, C. Birch, J. Braun +10 more

    2020Inflammatory Bowel Diseases20 citations Open access

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30. Reduced ischemia-reperfusion injury with isoproterenol in non-heart-beating donor lungs.

    David R. Jones, S. Hoffmann, Melanie Sellars, Thomas Egan

    1997Journal of Surgical Research18 citations

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31. Reverse Engineering of Digital Measures: Inviting Patients to the Conversation

    I. Clay, Nele Peerenboom, Dana E. Connors, Steven Bourke +33 more

    2023Digital Biomarkers15 citations Open access

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32. Renal epithelial cell‐derived monocyte colony stimulating factor as a local informant of renal injury and means of monocyte activation

    Kimberly A. Singh, Robert L. Kampen, S. Hoffmann, Shady M. Eldaif +1 more

    2009Transplant International10 citations

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33. Pulmonary preservation studies: effects on endothelial function and pulmonary adenine nucleotides

    H. Paik, S. Hoffmann, T. Egan

    2003Transplantation9 citations Open access

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34. Remote Cardiac Safety Monitoring through the Lens of the FDA Biomarker Qualification Evidentiary Criteria Framework: A Case Study Analysis

    E. Izmailova, W. Wood, Q. Liu, V. Zipunnikov +5 more

    2021Digital Biomarkers7 citations Open access

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35. Immunologic monitoring of the transplant recipient: challenges and approaches with antibody induction

    D. Hale, S. Swanson, R. Mannon, D. Kleiner +6 more

    20031 citations

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36. Maintenance of cAMP improves lung endothelial integrity in cadaveric rat lungs

    Mark S. Bleiweis, David R. Jones, S. Hoffmann, H. Paik +2 more

    19981 citations

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37. Toward actionable biomarkers in psychiatry: a collaborative roadmap for precision clinical trials. An ACNP position paper

    Sahib S. Khalsa, D. Barch, Linda S. Brady, Teresa Buracchio +20 more

    2026NPP—Digital Psychiatry and Neuroscience0 citations Open access

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38. Tolerance Model Results in Protection without Interactions in a Retinal Autoimmunity Disruption of CD 40 / CD 40-Ligand

    Chi-Chao Chan, R. Caspi, D. Harlan, S. Hoffmann +4 more

    20050 citations

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39. Modeling the Fontan circulation: a computer simulation of the effects of respiration

    Carol L. Lucas, M. Mill, W. Lucas, J. Sadoff +6 more

    1999Proceedings of the First Joint BMES/EMBS Conference. 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Annual Fall Meeting of the Biomedical Engineering Society (Cat. N0 citations

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40. Pulmonary preservation solutions: Effects on endothelial function and pulmonary energetics

    H. Paik, S. Hoffmann, A. Kiser, T. Egan

    19980 citations

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41. Are adhesion molecules upregulated after lung transplant from non-heart beating donors

    Yalaunda M. Thomas, H. Paik, S. Hoffmann, P. Ciriaco +4 more

    19980 citations

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