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R. Molfetta · SciRah

Researcher profile · Semantic Scholar

R. Molfetta

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R. Molfetta — researcher profile on SciRah

h-index: 31
Works: 84
Citations: 2,639

Most-cited papers

NKG2D and Its Ligands: “One for All, All for One”
A. Zingoni, R. Molfetta, C. Fionda, A. Soriani +4 more
2018Frontiers in Immunology238 citations Open access
Semantic Scholar
3D Microfluidic model for evaluating immunotherapy efficacy by tracking dendritic cell behaviour toward tumor cells
S. Parlato, A. De Ninno, R. Molfetta, E. Toschi +16 more
2017Scientific Reports174 citations Open access
Semantic Scholar
NK cells and interferons.
R. Paolini, G. Bernardini, R. Molfetta, A. Santoni
2015Cytokine & growth factor reviews154 citations
Semantic Scholar
Genotoxic stress modulates the release of exosomes from multiple myeloma cells capable of activating NK cell cytokine production: Role of HSP70/TLR2/NF-kB axis
E. Vulpis, Francesca Cecere, R. Molfetta, A. Soriani +14 more
2017Oncoimmunology109 citations Open access
Semantic Scholar
CD155: A Multi-Functional Molecule in Tumor Progression
R. Molfetta, B. Zitti, M. Lecce, N. D. Milito +6 more
2020International Journal of Molecular Sciences99 citations Open access
Semantic Scholar
Genotoxic Stress Induces Senescence-Associated ADAM10-Dependent Release of NKG2D MIC Ligands in Multiple Myeloma Cells
A. Zingoni, Francesca Cecere, E. Vulpis, C. Fionda +11 more
2015Journal of Immunology98 citations Open access
Semantic Scholar
Inhibition of bromodomain and extra-terminal (BET) proteins increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of cMYC-IRF4-miR-125b interplay
Maria Pia Abruzzese, M. Bilotta, C. Fionda, A. Zingoni +10 more
2016Journal of Hematology & Oncology92 citations Open access
Semantic Scholar
The IMiDs targets IKZF-1/3 and IRF4 as novel negative regulators of NK cell-activating ligands expression in multiple myeloma
C. Fionda, Maria Pia Abruzzese, A. Zingoni, Francesca Cecere +9 more
2015OncoTarget90 citations Open access
Semantic Scholar
Activation of Syk Tyrosine Kinase Is Required for c-Cbl-mediated Ubiquitination of FcεRI and Syk in RBL Cells*
R. Paolini, R. Molfetta, L. Beitz, Juan Zhang +5 more
2002Journal of Biological Chemistry84 citations Open access
Semantic Scholar
Regulation of NKG2D-Dependent NK Cell Functions: The Yin and the Yang of Receptor Endocytosis
R. Molfetta, L. Quatrini, A. Santoni, R. Paolini
2017International Journal of Molecular Sciences82 citations Open access
Semantic Scholar
Ubiquitination and degradation of Syk and ZAP-70 protein tyrosine kinases in human NK cells upon CD16 engagement
R. Paolini, R. Molfetta, M. Piccoli, L. Frati +1 more
2001Proceedings of the National Academy of Sciences of the United States of America69 citations Open access
Semantic Scholar
Ubiquitin-dependent endocytosis of NKG2D-DAP10 receptor complexes activates signaling and functions in human NK cells
L. Quatrini, R. Molfetta, B. Zitti, G. Peruzzi +6 more
2015Science Signaling63 citations Open access
Semantic Scholar
Nitric oxide donors increase PVR/CD155 DNAM-1 ligand expression in multiple myeloma cells: role of DNA damage response activation
C. Fionda, Maria Pia Abruzzese, A. Zingoni, A. Soriani +5 more
2015BMC Cancer59 citations Open access
Semantic Scholar
CIN85 Regulates the Ligand-Dependent Endocytosis of the IgE Receptor: A New Molecular Mechanism to Dampen Mast Cell Function1
R. Molfetta, F. Belleudi, G. Peruzzi, S. Morrone +7 more
2005Journal of Immunology59 citations Open access
Semantic Scholar
Regulation of NKG2D Expression and Signaling by Endocytosis.
R. Molfetta, L. Quatrini, B. Zitti, Cristina Capuano +3 more
2016Trends in immunology54 citations Open access
Semantic Scholar
Impact on NK cell functions of acute versus chronic exposure to extracellular vesicle‐associated MICA: Dual role in cancer immunosurveillance
E. Vulpis, Luisa Loconte, Agnese Peri, R. Molfetta +17 more
2022Journal of Extracellular Vesicles51 citations Open access
Semantic Scholar
Anti-CD20 Therapy Acts via Fc g RIIIA to Diminish Responsiveness of Human Natural Killer Cells
Cristina Capuano, M. Romanelli, Chiara Pighi, G. Cimino +5 more
201547 citations
Semantic Scholar
Regulation of Fc Receptor Endocytic Trafficking by Ubiquitination
R. Molfetta, L. Quatrini, Francesca Gasparrini, B. Zitti +2 more
2014Frontiers in Immunology47 citations Open access
Semantic Scholar
c‐Cbl regulates MICA‐ but not ULBP2‐induced NKG2D down‐modulation in human NK cells
R. Molfetta, L. Quatrini, Cristina Capuano, Francesca Gasparrini +5 more
2014European Journal of Immunology46 citations Open access
Semantic Scholar
Obinutuzumab-mediated high-affinity ligation of FcγRIIIA/CD16 primes NK cells for IFNγ production
Cristina Capuano, Chiara Pighi, R. Molfetta, R. Paolini +6 more
2017Oncoimmunology43 citations Open access
Semantic Scholar
Innate immune activating ligand SUMOylation affects tumor cell recognition by NK cells
B. Zitti, R. Molfetta, C. Fionda, L. Quatrini +9 more
2017Scientific Reports43 citations Open access
Semantic Scholar
NK Cells and Other Cytotoxic Innate Lymphocytes in Colorectal Cancer Progression and Metastasis
C. Fionda, Gianluca Scarno, H. Stabile, R. Molfetta +6 more
2022International Journal of Molecular Sciences40 citations Open access
Semantic Scholar
The Ubiquitin‐proteasome pathway regulates Nectin2/CD112 expression and impairs NK cell recognition and killing
R. Molfetta, N. D. Milito, B. Zitti, M. Lecce +4 more
2018European Journal of Immunology39 citations Open access
Semantic Scholar
Lipid Raft-Dependent FcεRI Ubiquitination Regulates Receptor Endocytosis through the Action of Ubiquitin Binding Adaptors
R. Molfetta, Francesca Gasparrini, G. Peruzzi, Laura Vian +4 more
2009PLoS ONE36 citations Open access
Semantic Scholar
PIP2-dependent regulation of Munc13-4 endocytic recycling: impact on the cytolytic secretory pathway.
Cristina Capuano, R. Paolini, R. Molfetta, L. Frati +2 more
2012Blood35 citations Open access
Semantic Scholar
Ubiquitination and endocytosis of the high affinity receptor for IgE.
R. Molfetta, Francesca Gasparrini, A. Santoni, R. Paolini
2010Molecular Immunology35 citations
Semantic Scholar
Activation of Syk tyrosine kinase is required for c-Cbl-mediated ubiquitination of Fcepsilon RI and Syk in RBL cells.
R. Paolini, R. Molfetta, L. Beitz, Juan Zhang +5 more
2002Journal of Biological Chemistry33 citations
Semantic Scholar
The Controversial Role of Intestinal Mast Cells in Colon Cancer
R. Molfetta, R. Paolini
2023Cells32 citations Open access
Semantic Scholar
Translating the anti-myeloma activity of Natural Killer cells into clinical application.
C. Fionda, H. Stabile, R. Molfetta, A. Soriani +6 more
2018Cancer Treatment Reviews32 citations
Semantic Scholar
CD155 and Its Receptors as Targets for Cancer Therapy
R. Paolini, R. Molfetta
2023International Journal of Molecular Sciences31 citations Open access
Semantic Scholar
FcεRI Signaling in the Modulation of Allergic Response: Role of Mast Cell-Derived Exosomes
M. Lecce, R. Molfetta, N. D. Milito, A. Santoni +1 more
2020International Journal of Molecular Sciences31 citations Open access
Semantic Scholar
p38 MAPK differentially controls NK activating ligands at transcriptional and post-transcriptional level on multiple myeloma cells
A. Soriani, C. Borrelli, Biancamaria Ricci, R. Molfetta +13 more
2017Oncoimmunology29 citations Open access
Semantic Scholar
NGF‐dependent and tissue‐specific transcription of vgf is regulated by a CREB–p300 and bHLH factor interaction
G. Mandolesi, Silvia Gargano, M. Pennuto, B. Illi +6 more
2002FEBS Letters29 citations Open access
Semantic Scholar
SCF and IL-33 regulate mouse mast cell phenotypic and functional plasticity supporting a pro-inflammatory microenvironment
R. Molfetta, M. Lecce, N. D. Milito, E. Putro +10 more
2023Cell Death and Disease28 citations Open access
Semantic Scholar
The Adaptor Molecule CIN85 Regulates Syk Tyrosine Kinase Level by Activating the Ubiquitin-Proteasome Degradation Pathway1
G. Peruzzi, R. Molfetta, Francesca Gasparrini, Laura Vian +5 more
2007Journal of Immunology27 citations Open access
Semantic Scholar
Bone Marrow Stromal Cell-Derived IL-8 Upregulates PVR Expression on Multiple Myeloma Cells via NF-kB Transcription Factor
Abdelilah Mekhloufi, Andrea Kosta, H. Stabile, R. Molfetta +12 more
2020Cancers26 citations Open access
Semantic Scholar
Post-translational Mechanisms Regulating NK Cell Activating Receptors and Their Ligands in Cancer: Potential Targets for Therapeutic Intervention
R. Molfetta, A. Zingoni, A. Santoni, R. Paolini
2019Frontiers in Immunology25 citations Open access
Semantic Scholar
Dysregulation of DNAM-1-Mediated NK Cell Anti-Cancer Responses in the Tumor Microenvironment
R. Paolini, R. Molfetta
2023Cancers23 citations Open access
Semantic Scholar
Immunomodulatory effect of NEDD8-activating enzyme inhibition in Multiple Myeloma: upregulation of NKG2D ligands and sensitization to Natural Killer cell recognition
Sara Petillo, Cristina Capuano, R. Molfetta, C. Fionda +10 more
2021Cell Death and Disease23 citations Open access
Semantic Scholar
Activation of liver X receptor up‐regulates the expression of the NKG2D ligands MICA and MICB in multiple myeloma through different molecular mechanisms
M. Bilotta, Maria Pia Abruzzese, R. Molfetta, Gianluca Scarno +9 more
2019The FASEB Journal22 citations
Semantic Scholar
Immune complexes exposed on mast cell‐derived nanovesicles amplify allergic inflammation
R. Molfetta, M. Lecce, L. Quatrini, G. Caracciolo +8 more
2019Allergy. European Journal of Allergy and Clinical Immunology22 citations Open access
Semantic Scholar
SAMHD1 phosphorylation and cytoplasmic relocalization after human cytomegalovirus infection limits its antiviral activity
S. De Meo, V. Dell’Oste, R. Molfetta, V. Tassinari +19 more
2020PLoS Pathogens21 citations Open access
Semantic Scholar
Tyrosine kinase‐dependent ubiquitination of CD16 ζ subunit in human NK cells following receptor engagement
R. Paolini, A. Serra, R. Molfetta, M. Piccoli +2 more
1999European Journal of Immunology21 citations Open access
Semantic Scholar
Negative signals from FcεRI engagement attenuate mast cell functions
R. Molfetta, G. Peruzzi, A. Santoni, R. Paolini
2007Archivum Immunologiae et Therapiae Experimentalis20 citations
Semantic Scholar
Syk‐dependent regulation of Hrs phosphorylation and ubiquitination upon FcεRI engagement: Impact on Hrs membrane/cytosol localization
Francesca Gasparrini, R. Molfetta, L. Quatrini, L. Frati +2 more
2012European Journal of Immunology18 citations
Semantic Scholar
NEDD8-activating enzyme inhibition potentiates the anti-myeloma activity of natural killer cells
Sara Petillo, Elena Sproviero, Luisa Loconte, Lorenzo Cuollo +10 more
2023Cell Death and Disease16 citations Open access
Semantic Scholar
The homeobox transcription factor MEIS2 is a regulator of cancer cell survival and IMiDs activity in Multiple Myeloma: modulation by Bromodomain and Extra-Terminal (BET) protein inhibitors
Maria Pia Abruzzese, M. Bilotta, C. Fionda, A. Zingoni +7 more
2019Cell Death and Disease16 citations Open access
Semantic Scholar
Optimizing Transfection Efficiency in CAR-T Cell Manufacturing through Multiple Administrations of Lipid-Based Nanoparticles.
Francesca Giulimondi, L. Digiacomo, Serena Renzi, Chiara Cassone +9 more
2024ACS Applied Bio Materials14 citations
Semantic Scholar
NKG2D engagement on human NK cells leads to DNAM‐1 hypo‐responsiveness through different converging mechanisms
N. D. Milito, A. Zingoni, H. Stabile, A. Soriani +6 more
2022European Journal of Immunology14 citations
Semantic Scholar
Cereblon regulates NK cell cytotoxicity and migration via Rac1 activation
C. Fionda, H. Stabile, R. Molfetta, Andrea Kosta +9 more
2021European Journal of Immunology13 citations Open access
Semantic Scholar

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R. Paolini — researcher profile on SciRah
A. Santoni×42
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A. Santoni — researcher profile on SciRah
A. Zingoni×21
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A. Zingoni — researcher profile on SciRah
C. Fionda×20
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M. Cippitelli — researcher profile on SciRah

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A. Soriani — researcher profile on SciRah

M. Petrucci×11

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M. Petrucci — researcher profile on SciRah

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G. Peruzzi — researcher profile on SciRah

M. R. Ricciardi×9

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M. R. Ricciardi — researcher profile on SciRah

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L. Frati — researcher profile on SciRah

Cristina Capuano×9

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Cristina Capuano — researcher profile on SciRah

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B. Zitti — researcher profile on SciRah