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G. Mandolesi · SciRah

Researcher profile · Semantic Scholar

G. Mandolesi

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G. Mandolesi — researcher profile on SciRah

h-index: 40
Works: 103
Citations: 4,352

Most-cited papers

Synaptopathy connects inflammation and neurodegeneration in multiple sclerosis
G. Mandolesi, A. Gentile, A. Musella, D. Fresegna +5 more
2015Nature Reviews Neurology245 citations
Semantic Scholar
Tumor Necrosis Factor and Interleukin-1β Modulate Synaptic Plasticity during Neuroinflammation
F. Rizzo, A. Musella, F. De Vito, D. Fresegna +8 more
2018Journal of Neural Transplantation and Plasticity217 citations Open access
Semantic Scholar
Siponimod (BAF312) prevents synaptic neurodegeneration in experimental multiple sclerosis
A. Gentile, A. Musella, S. Bullitta, D. Fresegna +9 more
2016Journal of Neuroinflammation152 citations Open access
Semantic Scholar
Inflammation Subverts Hippocampal Synaptic Plasticity in Experimental Multiple Sclerosis
R. Nisticò, D. Mango, G. Mandolesi, S. Piccinin +10 more
2013PLoS ONE149 citations Open access
Semantic Scholar
TNF-α-mediated anxiety in a mouse model of multiple sclerosis.
N. Haji, G. Mandolesi, A. Gentile, L. Sacchetti +10 more
2012Experimental Neurology144 citations
Semantic Scholar
Interleukin-1β Alters Glutamate Transmission at Purkinje Cell Synapses in a Mouse Model of Multiple Sclerosis
G. Mandolesi, A. Musella, A. Gentile, Giorgio Grasselli +9 more
2013Journal of Neuroscience137 citations Open access
Semantic Scholar
In vivo single branch axotomy induces GAP-43–dependent sprouting and synaptic remodeling in cerebellar cortex
A. L. Allegra Mascaro, P. Cesare, L. Sacconi, Giorgio Grasselli +7 more
2013Proceedings of the National Academy of Sciences of the United States of America121 citations Open access
Semantic Scholar
Acute physiological response of mammalian central neurons to axotomy: ionic regulation and electrical activity
G. Mandolesi, Federico Madeddu, Y. Bozzi, L. Maffei +1 more
2004The FASEB Journal114 citations
Semantic Scholar
Re-Examining the Role of TNF in MS Pathogenesis and Therapy
D. Fresegna, S. Bullitta, A. Musella, F. Rizzo +13 more
2020Cells112 citations Open access
Semantic Scholar
Obesity worsens central inflammation and disability in multiple sclerosis
Mario Stampanoni Bassi, E. Iezzi, F. Buttari, L. Gilio +16 more
2020Multiple Sclerosis112 citations
Semantic Scholar
Interplay Between Age and Neuroinflammation in Multiple Sclerosis: Effects on Motor and Cognitive Functions
A. Musella, A. Gentile, F. Rizzo, F. De Vito +8 more
2018Frontiers in Aging Neuroscience107 citations Open access
Semantic Scholar
Impaired striatal GABA transmission in experimental autoimmune encephalomyelitis.
S. Rossi, L. Muzio, V. De Chiara, Giorgio Grasselli +12 more
2011Brain, behavior, and immunity103 citations
Semantic Scholar
Cholinergic dysfunction alters synaptic integration between thalamostriatal and corticostriatal inputs in DYT1 dystonia
G. Sciamanna, Annalisa Tassone, G. Mandolesi, F. Puglisi +7 more
2012Journal of Neuroscience101 citations Open access
Semantic Scholar
Dopamine D2 receptor dysfunction is rescued by adenosine A2A receptor antagonism in a model of DYT1 dystonia
F. Napolitano, M. Pasqualetti, A. Usiello, E. Santini +13 more
2010Neurobiology of Disease92 citations Open access
Semantic Scholar
Neuroinflammation Is Associated with GFAP and sTREM2 Levels in Multiple Sclerosis
Federica Azzolini, L. Gilio, L. Pavone, E. Iezzi +13 more
2022Biomolecules86 citations Open access
Semantic Scholar
Cerebrospinal fluid lactate is associated with multiple sclerosis disease progression
M. Albanese, S. Zagaglia, D. Landi, L. Boffa +7 more
2016Journal of Neuroinflammation84 citations Open access
Semantic Scholar
Cognitive deficits in experimental autoimmune encephalomyelitis: neuroinflammation and synaptic degeneration
G. Mandolesi, Giorgio Grasselli, G. Musumeci, D. Centonze
2010Neurological Sciences80 citations
Semantic Scholar
Developmental Profile of the Aberrant Dopamine D2 Receptor Response in Striatal Cholinergic Interneurons in DYT1 Dystonia
G. Sciamanna, Annalisa Tassone, Giuseppina Martella, G. Mandolesi +7 more
2011PLoS ONE79 citations Open access
Semantic Scholar
Regional specificity of synaptic plasticity deficits in a knock-in mouse model of DYT1 dystonia.
Giuseppina Martella, Marta Maltese, R. Nisticò, T. Schirinzi +9 more
2014Neurobiology of Disease77 citations Open access
Semantic Scholar
Interleukin-1β Promotes Long-Term Potentiation in Patients with Multiple Sclerosis
F. Mori, R. Nisticò, G. Mandolesi, S. Piccinin +13 more
2014Neuromolecular medicine68 citations
Semantic Scholar
miR-142-3p is a key regulator of IL-1β-dependent synaptopathy in neuroinflammation.
G. Mandolesi, F. De Vito, A. Musella, A. Gentile +13 more
2017Journal of Neuroscience67 citations Open access
Semantic Scholar
Inflammation-Associated Synaptic Alterations as Shared Threads in Depression and Multiple Sclerosis
Antonio Bruno, Ettore Dolcetti, F. Rizzo, D. Fresegna +13 more
2020Frontiers in Cellular Neuroscience65 citations Open access
Semantic Scholar
A novel crosstalk within the endocannabinoid system controls GABA transmission in the striatum
A. Musella, D. Fresegna, F. Rizzo, A. Gentile +5 more
2017Scientific Reports61 citations Open access
Semantic Scholar
Transient receptor potential vanilloid 1 channels modulate the synaptic effects of TNF-α and of IL-1β in experimental autoimmune encephalomyelitis
G. Musumeci, Giorgio Grasselli, S. Rossi, V. De Chiara +10 more
2011Neurobiology of Disease60 citations Open access
Semantic Scholar
Voluntary running wheel attenuates motor deterioration and brain damage in cuprizone-induced demyelination.
G. Mandolesi, S. Bullitta, D. Fresegna, F. De Vito +9 more
2019Neurobiology of Disease59 citations Open access
Semantic Scholar
miR-142-3p Is a Key Regulator of IL-1β-Dependent Synaptopathy in Neuroinflammation
G. Mandolesi, F. De Vito, A. Musella, A. Gentile +13 more
2017Journal of Neuroscience59 citations Open access
Semantic Scholar
Emerging Role of Extracellular Vesicles in the Pathophysiology of Multiple Sclerosis
Ettore Dolcetti, Antonio Bruno, L. Guadalupi, F. Rizzo +13 more
2020International Journal of Molecular Sciences55 citations Open access
Semantic Scholar
RANTES correlates with inflammatory activity and synaptic excitability in multiple sclerosis
F. Mori, R. Nisticò, C. Nicoletti, S. Zagaglia +8 more
2016Multiple Sclerosis55 citations Open access
Semantic Scholar
A role for retinal brain-derived neurotrophic factor in ocular dominance plasticity.
G. Mandolesi, E. Menna, A. Harauzov, C. V. von Bartheld +2 more
2005Current Biology55 citations Open access
Semantic Scholar
Immunomodulatory Effects of Exercise in Experimental Multiple Sclerosis
A. Gentile, A. Musella, F. De Vito, F. Rizzo +8 more
2019Frontiers in Immunology52 citations Open access
Semantic Scholar
Dopaminergic dysfunction is associated with IL-1β-dependent mood alterations in experimental autoimmune encephalomyelitis.
A. Gentile, D. Fresegna, M. Federici, A. Musella +10 more
2015Neurobiology of Disease51 citations Open access
Semantic Scholar
GABAergic signaling and connectivity on Purkinje cells are impaired in experimental autoimmune encephalomyelitis.
G. Mandolesi, Giorgio Grasselli, A. Musella, A. Gentile +6 more
2012Neurobiology of Disease51 citations Open access
Semantic Scholar
Optogenetic stimulation reveals distinct modulatory properties of thalamostriatal vs corticostriatal glutamatergic inputs to fast-spiking interneurons
G. Sciamanna, Giulia Ponterio, G. Mandolesi, P. Bonsi +1 more
2015Scientific Reports49 citations Open access
Semantic Scholar
Interleukin-6 Disrupts Synaptic Plasticity and Impairs Tissue Damage Compensation in Multiple Sclerosis
Mario Stampanoni Bassi, E. Iezzi, F. Mori, I. Simonelli +14 more
2019Neurorehabilitation and Neural Repair47 citations
Semantic Scholar
AMBRA1 Controls Regulatory T-Cell Differentiation and Homeostasis Upstream of the FOXO3-FOXP3 Axis.
Juliane Becher, Luca Simula, E. Volpe, C. Procaccini +27 more
2018Developmental Cell47 citations Open access
Semantic Scholar
Impaired Sprouting and Axonal Atrophy in Cerebellar Climbing Fibres following In Vivo Silencing of the Growth-Associated Protein GAP-43
Giorgio Grasselli, G. Mandolesi, P. Strata, P. Cesare
2011PLoS ONE47 citations Open access
Semantic Scholar
Delayed treatment of MS is associated with high CSF levels of IL-6 and IL-8 and worse future disease course
Mario Stampanoni Bassi, E. Iezzi, D. Landi, Fabrizia Monteleone +10 more
2018Journal of Neurology46 citations
Semantic Scholar
Abnormal NMDA receptor function exacerbates experimental autoimmune encephalomyelitis
Giorgio Grasselli, S. Rossi, A. Musella, A. Gentile +14 more
2013British Journal of Pharmacology46 citations Open access
Semantic Scholar
Exposure to low-dose rotenone precipitates synaptic plasticity alterations in PINK1 heterozygous knockout mice.
Giuseppina Martella, G. Madeo, Marta Maltese, V. Vanni +10 more
2016Neurobiology of Disease44 citations Open access
Semantic Scholar
Exercise protects from hippocampal inflammation and neurodegeneration in experimental autoimmune encephalomyelitis.
Francesca Romana Rizzo, L. Guadalupi, Krizia Sanna, V. Vanni +14 more
2021Brain, behavior, and immunity43 citations Open access
Semantic Scholar
Interaction between interleukin-1β and type-1 cannabinoid receptor is involved in anxiety-like behavior in experimental autoimmune encephalomyelitis
A. Gentile, D. Fresegna, A. Musella, H. Sepman +9 more
2016Journal of Neuroinflammation42 citations Open access
Semantic Scholar
Cerebellar synaptogenesis is compromised in mouse models of DYT1 dystonia.
V. Vanni, F. Puglisi, P. Bonsi, Giulia Ponterio +3 more
2015Experimental Neurology39 citations
Semantic Scholar
The microRNA let-7b-5p Is Negatively Associated with Inflammation and Disease Severity in Multiple Sclerosis
G. Mandolesi, F. Rizzo, Sara Balletta, Mario Stampanoni Bassi +23 more
2021Cells36 citations Open access
Semantic Scholar
Central Modulation of Selective Sphingosine-1-Phosphate Receptor 1 Ameliorates Experimental Multiple Sclerosis
A. Musella, A. Gentile, L. Guadalupi, F. Rizzo +15 more
2020Cells36 citations Open access
Semantic Scholar
Il-1β Dependent Cerebellar Synaptopathy in a Mouse Mode of Multiple Sclerosis
G. Mandolesi, A. Gentile, A. Musella, D. Centonze
2015Cerebellum31 citations
Semantic Scholar
Inflammatory signature in amyotrophic lateral sclerosis predicting disease progression
C. Femiano, Antonio Bruno, L. Gilio, F. Buttari +11 more
2024Scientific Reports30 citations Open access
Semantic Scholar
Pre- and postsynaptic type-1 cannabinoid receptors control the alterations of glutamate transmission in experimental autoimmune encephalomyelitis.
A. Musella, H. Sepman, G. Mandolesi, A. Gentile +6 more
2014Neuropharmacology30 citations
Semantic Scholar
Cladribine interferes with IL-1β synaptic effects in experimental multiple sclerosis.
A. Musella, G. Mandolesi, A. Gentile, S. Rossi +8 more
2013Journal of Neuroimmunology29 citations
Semantic Scholar
MiR‐142‐3p regulates synaptopathy‐driven disease progression in multiple sclerosis
F. De Vito, A. Musella, D. Fresegna, F. Rizzo +27 more
2021Neuropathology and Applied Neurobiology28 citations Open access
Semantic Scholar
Laquinimod ameliorates excitotoxic damage by regulating glutamate re-uptake
A. Gentile, A. Musella, F. De Vito, D. Fresegna +4 more
2018Journal of Neuroinflammation28 citations Open access
Semantic Scholar

Frequent co-authors

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D. Centonze×38
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D. Centonze — researcher profile on SciRah
A. Musella×35
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A. Musella — researcher profile on SciRah
A. Gentile×28
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A. Gentile — researcher profile on SciRah
D. Fresegna×26
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D. Fresegna — researcher profile on SciRah

×22

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F. De Vito — researcher profile on SciRah

S. Bullitta×20

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S. Bullitta — researcher profile on SciRah

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F. Buttari — researcher profile on SciRah

Mario Stampanoni Bassi×16

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Mario Stampanoni Bassi — researcher profile on SciRah

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F. Rizzo — researcher profile on SciRah

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V. Vanni — researcher profile on SciRah

L. Guadalupi×13

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L. Guadalupi — researcher profile on SciRah

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H. Sepman — researcher profile on SciRah