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K. Aoki · SciRah

Researcher profile · Semantic Scholar

K. Aoki

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K. Aoki — researcher profile on SciRah

h-index: 33
Works: 120
Citations: 5,165

Most-cited papers

Coupling of bone resorption and formation by RANKL reverse signalling
Yuki Ikebuchi, Shigeki Aoki, Masashi Honma, Madoka Hayashi +9 more
2018Nature512 citations
Semantic Scholar
Regulation of osteoclast differentiation and function by the CaMK-CREB pathway
Kojiro Sato, Ayako Suematsu, T. Nakashima, Sayaka Takemoto-Kimura +10 more
2006Nature Medicine345 citations
Semantic Scholar
Cathepsin K-Dependent Toll-Like Receptor 9 Signaling Revealed in Experimental Arthritis
M. Asagiri, T. Hirai, T. Kunigami, Shunya Kamano +13 more
2008Science299 citations
Semantic Scholar
IκBζ regulates TH17 development by cooperating with ROR nuclear receptors
Kazuo Okamoto, Yoshiko Iwai, M. Oh-hora, Masahiro Yamamoto +7 more
2010Nature254 citations
Semantic Scholar
Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2−/− mice
H. Gil-Henn, O. Destaing, N. Sims, K. Aoki +7 more
2007Journal of Cell Biology233 citations Open access
Semantic Scholar
Signaling pathway via TNF-alpha/NF-kappaB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis.
Michio Onizawa, Takashi Nagaishi, T. Kanai, Kenichi Nagano +12 more
2009American Journal of Physiology - Gastrointestinal and Liver Physiology165 citations
Semantic Scholar
A TNF receptor loop peptide mimic blocks RANK ligand-induced signaling, bone resorption, and bone loss.
K. Aoki, H. Saito, C. Itzstein, M. Ishiguro +13 more
2006Journal of Clinical Investigation134 citations Open access
Semantic Scholar
Osteoclast formation and differentiation: an overview.
N. Soysa, N. Alles, K. Aoki, K. Ohya
2012Journal of Medical and Dental Sciences127 citations
Semantic Scholar
Suppression of NF-kappaB increases bone formation and ameliorates osteopenia in ovariectomized mice.
N. Alles, N. Soysa, Juri Hayashi, Masud Khan +6 more
2010Endocrinology96 citations Open access
Semantic Scholar
Phytic acid: an alternative root canal chelating agent.
Mohannad Nassar, N. Hiraishi, Yukihiko Tamura, M. Otsuki +2 more
2015Journal of Endodontics82 citations
Semantic Scholar
The pivotal role of the alternative NF‐κB pathway in maintenance of basal bone homeostasis and osteoclastogenesis
N. Soysa, N. Alles, Debra S. Weih, Á. Lovas +7 more
2009Journal of Bone and Mineral Research77 citations Open access
Semantic Scholar
Stimulation of Bone Formation in Cortical Bone of Mice Treated with a Receptor Activator of Nuclear Factor-κB Ligand (RANKL)-binding Peptide That Possesses Osteoclastogenesis Inhibitory Activity
Y. Furuya, A. Inagaki, Masud Khan, K. Mori +7 more
2013Journal of Biological Chemistry74 citations Open access
Semantic Scholar
Microgravity promotes osteoclast activity in medaka fish reared at the international space station
M. Chatani, A. Mantoku, Kazuhiro Takeyama, Dawud Abduweli +11 more
2015Scientific Reports70 citations Open access
Semantic Scholar
Amelioration of bone loss in collagen-induced arthritis by neutralizing anti-RANKL monoclonal antibody.
S. Kamijo, A. Nakajima, K. Ikeda, K. Aoki +4 more
2006Biochemical and Biophysical Research Communications - BBRC70 citations
Semantic Scholar
Polysaccharide nanogel delivery of a TNF-alpha and RANKL antagonist peptide allows systemic prevention of bone loss.
N. Alles, N. Soysa, M. D. Anower Hussain, N. Tomomatsu +6 more
2009European Journal of Pharmaceutical Sciences60 citations
Semantic Scholar
A tumor necrosis factor receptor loop peptide mimic inhibits bone destruction to the same extent as anti-tumor necrosis factor monoclonal antibody in murine collagen-induced arthritis.
H. Saito, Takefumi Kojima, Mariko Takahashi, W. Horne +4 more
2007Arthritis & Rheumatism58 citations
Semantic Scholar
Processing of the NF‐κB2 precursor p100 to p52 is critical for RANKL‐induced osteoclast differentiation
Toshimasa Maruyama, H. Fukushima, K. Nakao, M. Shin +8 more
2009Journal of Bone and Mineral Research55 citations Open access
Semantic Scholar
Peptide-based delivery to bone.
K. Aoki, N. Alles, N. Soysa, K. Ohya
2012Advanced Drug Delivery Reviews52 citations
Semantic Scholar
LPS‐Induced Inhibition of Osteogenesis Is TNF‐α Dependent in a Murine Tooth Extraction Model
N. Tomomatsu, K. Aoki, N. Alles, N. Soysa +6 more
2009Journal of Bone and Mineral Research51 citations
Semantic Scholar
Inhibition of the classical NF-κB pathway prevents osteoclast bone-resorbing activity
N. Soysa, N. Alles, H. Shimokawa, E. Jimi +2 more
2009Journal of Bone and Mineral Metabolism48 citations
Semantic Scholar
Inhibition of BMP2-induced bone formation by the p65 subunit of NF-κB via an interaction with Smad4.
S. Hirata-Tsuchiya, H. Fukushima, T. Katagiri, Satoshi Ohte +14 more
2014Molecular Endocrinology45 citations Open access
Semantic Scholar
p130Cas, Crk‐Associated Substrate, Plays Important Roles in Osteoclastic Bone Resorption
Yoshie Nagai, Kenji Osawa, H. Fukushima, Yukihiko Tamura +13 more
2013Journal of Bone and Mineral Research45 citations
Semantic Scholar
Ligature induced peri‐implantitis: tissue destruction and inflammatory progression in a murine model
Trang N. Nguyen Vo, J. Hao, J. Chou, M. Oshima +4 more
2017Clinical Oral Implants Research44 citations
Semantic Scholar
Decontamination of Anodized Implant Surface With Different Modalities for Peri-Implantitis Treatment: Lasers and Mechanical Debridement With Citric Acid.
M. Htet, M. Madi, Osama Zakaria, T. Miyahara +4 more
2016The Journal of Periodontology41 citations
Semantic Scholar
Disruption of NF‐κB1 prevents bone loss caused by mechanical unloading
Hitomi Nakamura, K. Aoki, Wataru Masuda, N. Alles +9 more
2013Journal of Bone and Mineral Research40 citations Open access
Semantic Scholar
CXCL2 synthesized by oral squamous cell carcinoma is involved in cancer-associated bone destruction.
Erika Oue, Ji-Won Lee, K. Sakamoto, T. Iimura +7 more
2012Biochemical and Biophysical Research Communications - BBRC36 citations
Semantic Scholar
Low‐level ultrahigh‐frequency and ultrashort‐pulse blue laser irradiation enhances osteoblast extracellular calcification by upregulating proliferation and differentiation via transient receptor potential vanilloid 1
Risako Mikami, K. Mizutani, A. Aoki, Yukihiko Tamura +2 more
2018Lasers in Surgery and Medicine35 citations
Semantic Scholar
The inhibitory effects of a RANKL-binding peptide on articular and periarticular bone loss in a murine model of collagen-induced arthritis: a bone histomorphometric study
Genki Kato, Y. Shimizu, Y. Arai, Natsuki Suzuki +10 more
2015Arthritis Research & Therapy34 citations Open access
Semantic Scholar
Characterization of pulp and follicle stem cells from impacted supernumerary maxillary incisors.
K. Shoi, K. Aoki, K. Ohya, Y. Takagi +1 more
2014Pediatric Dentistry34 citations
Semantic Scholar
Selective inhibition of NF‐κB suppresses bone invasion by oral squamous cell carcinoma in vivo
H. Furuta, Kenji Osawa, M. Shin, Ayataka Ishikawa +9 more
2012International Journal of Cancer34 citations
Semantic Scholar
A novel inhibitor of NF-κB-inducing kinase prevents bone loss by inhibiting osteoclastic bone resorption in ovariectomized mice.
Nana Takakura, M. Matsuda, Masud Khan, F. Hiura +7 more
2020Bone29 citations
Semantic Scholar
Peptide drugs accelerate BMP‐2‐induced calvarial bone regeneration and stimulate osteoblast differentiation through mTORC1 signaling
Yasutaka Sugamori, S. Mise-Omata, Chizuko Maeda, Shigeki Aoki +7 more
2016Bioessays29 citations Open access
Semantic Scholar
A peptide that blocks the interaction of NF‐κB p65 subunit with Smad4 enhances BMP2‐induced osteogenesis
Mariko Urata, S. Kokabu, T. Matsubara, Goro Sugiyama +12 more
2018Journal of Cellular Physiology28 citations Open access
Semantic Scholar
A novel underuse model shows that inactivity but not ovariectomy determines the deteriorated material properties and geometry of cortical bone in the tibia of adult rats
K. Miyagawa, Y. Kozai, Yumi Ito, T. Furuhama +8 more
2010Journal of Bone and Mineral Metabolism28 citations Open access
Semantic Scholar
Accumulation of p100, a precursor of NF-κB2, enhances osteoblastic differentiation in vitro and bone formation in vivo in aly/aly mice.
Yoshinori Seo, H. Fukushima, Toshimasa Maruyama, Kayoko N. Kuroishi +10 more
2012Molecular Endocrinology26 citations Open access
Semantic Scholar
Delivery of RANKL-Binding Peptide OP3-4 Promotes BMP-2–Induced Maxillary Bone Regeneration
T. Uehara, S. Mise-Omata, M. Matsui, Y. Tabata +3 more
2016Journal of dentistry research24 citations
Semantic Scholar
NF-κB inhibitor dehydroxymethylepoxyquinomicin suppresses osteoclastogenesis and expression of NFATc1 in mouse arthritis without affecting expression of RANKL, osteoprotegerin or macrophage colony-stimulating factor
T. Kubota, M. Hoshino, K. Aoki, K. Ohya +4 more
2007Arthritis Research & Therapy24 citations Open access
Semantic Scholar
Inhibition of RANKL-induced osteoclastogenesis by (-)-DHMEQ, a novel NF-kappaB inhibitor, through downregulation of NFATc1.
H. Takatsuna, M. Asagiri, Takeshi Kubota, Kotaro Oka +7 more
2005Journal of Bone and Mineral Research24 citations
Semantic Scholar
The induction of RANKL molecule clustering could stimulate early osteoblast differentiation.
E. Sone, D. Noshiro, Yuki Ikebuchi, Mami Nakagawa +11 more
2019Biochemical and Biophysical Research Communications - BBRC23 citations
Semantic Scholar
Peptide-induced de novo bone formation after tooth extraction prevents alveolar bone loss in a murine tooth extraction model.
Y. Arai, K. Aoki, Y. Shimizu, Y. Tabata +4 more
2016European Journal of Pharmacology23 citations
Semantic Scholar
Regional distinctions in cortical bone mineral density measured by pQCT can predict alterations in material property at the tibial diaphysis of the Cynomolgus monkey.
K. Nonaka, S. Fukuda, K. Aoki, T. Yoshida +1 more
2006Bone23 citations Open access
Semantic Scholar
NF-κB RELA-deficient bone marrow macrophages fail to support bone formation and to maintain the hematopoietic niche after lethal irradiation and stem cell transplantation.
S. Mise-Omata, N. Alles, T. Fukazawa, K. Aoki +4 more
2014International Immunology21 citations
Semantic Scholar
The local administration of TNF-α and RANKL antagonist peptide promotes BMP-2-induced bone formation
Abdulla Al Masud Khan, N. Alles, N. Soysa, Md. Abdullah Al Mamun +6 more
201321 citations
Semantic Scholar
The tumor necrosis factor type 2 receptor plays a protective role in tumor necrosis factor-α-induced bone resorption lacunae on mouse calvariae
Kenichi Nagano, N. Alles, A. H. Mian, A. Shimoda +6 more
2011Journal of Bone and Mineral Metabolism20 citations
Semantic Scholar
Increased bone mass in adult prostacyclin-deficient mice.
Chalida Nakalekha, C. Yokoyama, Hiroyuki Miura, N. Alles +3 more
2010Journal of Endocrinology20 citations Open access
Semantic Scholar
A tumor necrosis factor-alpha antagonist inhibits inflammatory bone resorption induced by Porphyromonas gingivalis infection in mice.
Yoshifumi Suzuki, K. Aoki, H. Saito, M. Umeda +3 more
2006Journal of Periodontal Research20 citations
Semantic Scholar
Effect of load-induced local mechanical strain on peri-implant bone cell activity related to bone resorption and formation in mice: An analysis of histology and strain distributions.
Hisami Okawara, Y. Arai, Hitomi Matsuno, P. Marcián +3 more
2021Journal of The Mechanical Behavior of Biomedical Materials19 citations
Semantic Scholar
Bacterial Inhibition and Osteoblast Adhesion on Ti Alloy Surfaces Modified by Poly(PEGMA- r-Phosmer) Coating.
Xinnan Cui, T. Murakami, Yukihiko Tamura, K. Aoki +2 more
2018ACS Applied Materials and Interfaces19 citations
Semantic Scholar
Gelatin hydrogel as a carrier of recombinant human fibroblast growth factor-2 during rat mandibular distraction.
A. Kimura, Y. Kabasawa, Y. Tabata, K. Aoki +2 more
2014Journal of oral and maxillofacial surgery19 citations
Semantic Scholar
Gelatin hydrogel carrier with the W9-peptide elicits synergistic effects on BMP-2-induced bone regeneration
Md. Abdullah Al Mamun, Md. Abdulla Al Masud Khan, N. Alles, M. Matsui +3 more
201319 citations
Semantic Scholar

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K. Ohya×34
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