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R. Graham · SciRah

Researcher profile · Semantic Scholar

R. Graham

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R. Graham — researcher profile on SciRah

h-index: 42
Works: 77
Citations: 18K

Most-cited papers

Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus
Yu-Shun Wan, J. Shang, R. Graham, R. Baric +1 more
2020Journal of Virology3,729 citations Open access
Semantic Scholar
Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses
T. Sheahan, A. Sims, R. Graham, V. Menachery +19 more
2017Science Translational Medicine1,520 citations Open access
Semantic Scholar
Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease
Maria L. Agostini, Erica L. Andres, A. Sims, R. Graham +13 more
2018mBio1,328 citations Open access
Semantic Scholar
An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice
T. Sheahan, A. Sims, Shuntai Zhou, R. Graham +24 more
2020Science Translational Medicine1,006 citations Open access
Semantic Scholar
SARS-like cluster of circulating bat coronavirus pose threat for human emergence
V. Menachery, B. Yount, K. Debbink, S. Agnihothram +11 more
2015Nature Medicine896 citations Open access
Semantic Scholar
SARS-CoV-2 D614G Variant Exhibits Efficient Replication ex vivo and Transmission in vivo
Yixuan J. Hou, S. Chiba, Peter J. Halfmann, C. Ehre +22 more
2020Science842 citations Open access
Semantic Scholar
Recombination, Reservoirs, and the Modular Spike: Mechanisms of Coronavirus Cross-Species Transmission
R. Graham, R. Baric
2009Journal of Virology692 citations Open access
Semantic Scholar
A decade after SARS: Strategies to control emerging coronaviruses
R. Graham, Eric F. Donaldson, R. Baric
2013Nature Reviews Microbiology657 citations Open access
Semantic Scholar
Receptor recognition by novel coronavirus from Wuhan: 2 An analysis based on decade-long structural studies of SARS 3
Yu-Shun Wan, J. Shang, R. Graham, R. Baric +1 more
2020597 citations
Semantic Scholar
Coronaviruses
M. Denison, R. Graham, Eric F. Donaldson, Lance D. Eckerle +1 more
2011RNA Biology592 citations Open access
Semantic Scholar
Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase
Ariane J. Brown, John J. Won, R. Graham, Kenneth H. Dinnon +6 more
2019Antiviral Research476 citations Open access
Semantic Scholar
Infidelity of SARS-CoV Nsp14-Exonuclease Mutant Virus Replication Is Revealed by Complete Genome Sequencing
Lance D. Eckerle, M. M. Becker, R. Halpin, Kelvin Li +8 more
2010PLoS Pathogens456 citations Open access
Semantic Scholar
Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice
Andrea J. Pruijssers, Amelia S. George, A. Schäfer, S. Leist +25 more
2020Cell Reports448 citations Open access
Semantic Scholar
SARS-like WIV1-CoV poised for human emergence
V. Menachery, B. Yount, A. Sims, K. Debbink +14 more
2016Proceedings of the National Academy of Sciences of the United States of America419 citations Open access
Semantic Scholar
Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus
T. Scobey, B. Yount, A. Sims, Eric F. Donaldson +9 more
2013Proceedings of the National Academy of Sciences of the United States of America293 citations Open access
Semantic Scholar
Cell Host Response to Infection with Novel Human Coronavirus EMC Predicts Potential Antivirals and Important Differences with SARS Coronavirus
L. Josset, V. Menachery, Lisa E. Gralinski, S. Agnihothram +6 more
2013mBio282 citations Open access
Semantic Scholar
Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice
M. M. Becker, R. Graham, Eric F. Donaldson, B. Rockx +7 more
2008Proceedings of the National Academy of Sciences of the United States of America279 citations Open access
Semantic Scholar
Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution
Xianchun Tang, S. Agnihothram, Yongjun Jiao, Jeremy Stanhope +8 more
2014Proceedings of the National Academy of Sciences of the United States of America250 citations Open access
Semantic Scholar
A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease
R. Graham, M. M. Becker, Lance D. Eckerle, Meagan Bolles +2 more
2012Nature Medicine227 citations Open access
Semantic Scholar
Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection
V. Menachery, Kenneth H. Dinnon, B. Yount, Eileen T. McAnarney +10 more
2019Journal of Virology191 citations Open access
Semantic Scholar
The nsp2 Replicase Proteins of Murine Hepatitis Virus and Severe Acute Respiratory Syndrome Coronavirus Are Dispensable for Viral Replication
R. Graham, A. Sims, Sarah M Brockway, R. Baric +1 more
2005Journal of Virology190 citations Open access
Semantic Scholar
Swine acute diarrhea syndrome coronavirus replication in primary human cells reveals potential susceptibility to infection
C. Edwards, B. Yount, R. Graham, S. Leist +10 more
2020Proceedings of the National Academy of Sciences of the United States of America149 citations Open access
Semantic Scholar
SARS coronavirus replicase proteins in pathogenesis
R. Graham, Jennifer S Sparks, Lance D. Eckerle, A. Sims +1 more
2007Virus Research143 citations Open access
Semantic Scholar
MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis
V. Menachery, H. Mitchell, A. Cockrell, Lisa E. Gralinski +12 more
2017mBio137 citations Open access
Semantic Scholar
Jumping species – A Mechanism for Coronavirus Persistence and Survival
V. Menachery, R. Graham, R. Baric
2017Current Opinion in Virology134 citations Open access
Semantic Scholar
Evaluation of Serologic and Antigenic Relationships Between Middle Eastern Respiratory Syndrome Coronavirus and Other Coronaviruses to Develop Vaccine Platforms for the Rapid Response to Emerging Coronaviruses
S. Agnihothram, R. Gopal, B. Yount, Eric F. Donaldson +7 more
2013Journal of Infectious Diseases110 citations Open access
Semantic Scholar
Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis
V. Menachery, Lisa E. Gralinski, H. Mitchell, Kenneth H. Dinnon +10 more
2017Msphere100 citations Open access
Semantic Scholar
Processing of Open Reading Frame 1a Replicase Proteins nsp7 to nsp10 in Murine Hepatitis Virus Strain A59 Replication
Damon J. Deming, R. Graham, M. Denison, R. Baric
2007Journal of Virology99 citations Open access
Semantic Scholar
Single-Amino-Acid Substitutions in Open Reading Frame (ORF) 1b-nsp14 and ORF 2a Proteins of the Coronavirus Mouse Hepatitis Virus Are Attenuating in Mice
Steven M. Sperry, Lubna Kazi, R. Graham, R. Baric +2 more
2005Journal of Virology99 citations Open access
Semantic Scholar
The Current and Future State of Vaccines, Antivirals and Gene Therapies Against Emerging Coronaviruses
Long-Ping V. Tse, Rita M. Meganck, R. Graham, R. Baric
2020Frontiers in Microbiology89 citations Open access
Semantic Scholar
Combination Attenuation Offers Strategy for Live Attenuated Coronavirus Vaccines
V. Menachery, Lisa E. Gralinski, H. Mitchell, Kenneth H. Dinnon +6 more
2018Journal of Virology70 citations Open access
Semantic Scholar
A Mouse Model for Betacoronavirus Subgroup 2c Using a Bat Coronavirus Strain HKU5 Variant
S. Agnihothram, B. Yount, Eric F. Donaldson, Jeremy Huynh +15 more
2014mBio69 citations Open access
Semantic Scholar
Genetic Variation between Dengue Virus Type 4 Strains Impacts Human Antibody Binding and Neutralization
Emily N. Gallichotte, Thomas J. Baric, U. Nivarthi, Matthew J. Delacruz +7 more
2018Cell Reports68 citations Open access
Semantic Scholar
Remdesivir potently inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice
Andrea J. Pruijssers, Amelia S. George, A. Schäfer, S. Leist +25 more
2020bioRxiv61 citations Open access
Semantic Scholar
Evaluation of a recombination-resistant coronavirus as a broadly applicable, rapidly implementable vaccine platform
R. Graham, Damon J. Deming, M. Deming, B. Yount +1 more
2018Communications Biology58 citations Open access
Semantic Scholar
GII.4 Human Norovirus: Surveying the Antigenic Landscape
Michael L. Mallory, L. Lindesmith, R. Graham, R. Baric
2019Viruses57 citations Open access
Semantic Scholar
Murine Hepatitis Virus Replicase Protein nsp10 Is a Critical Regulator of Viral RNA Synthesis
Eric F. Donaldson, A. Sims, R. Graham, M. Denison +1 more
2007Journal of Virology54 citations Open access
Semantic Scholar
Analysis of Murine Hepatitis Virus Strain A59 Temperature-Sensitive Mutant TS-LA6 Suggests that nsp10 Plays a Critical Role in Polyprotein Processing
Eric F. Donaldson, R. Graham, A. Sims, M. Denison +1 more
2007Journal of Virology51 citations Open access
Semantic Scholar
Cleavage between Replicase Proteins p28 and p65 of Mouse Hepatitis Virus Is Not Required for Virus Replication
M. Denison, B. Yount, Sarah M Brockway, R. Graham +3 more
2004Journal of Virology49 citations Open access
Semantic Scholar
An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 and multiple endemic, epidemic and bat coronavirus
T. Sheahan, A. Sims, Shuntai Zhou, R. Graham +20 more
2020bioRxiv48 citations Open access
Semantic Scholar
Conformational Occlusion of Blockade Antibody Epitopes, a Novel Mechanism of GII.4 Human Norovirus Immune Evasion
L. Lindesmith, Michael L. Mallory, K. Debbink, Eric F. Donaldson +8 more
2018Msphere48 citations Open access
Semantic Scholar
Replication of Murine Hepatitis Virus Is Regulated by Papain-Like Proteinase 1 Processing of Nonstructural Proteins 1, 2, and 3
R. Graham, M. Denison
2006Journal of Virology41 citations Open access
Semantic Scholar
Comparative analysis of coronavirus genomic RNA structure reveals conservation in SARS-like coronaviruses
Wes Sanders, Ethan J. Fritch, E. A. Madden, R. Graham +4 more
2020bioRxiv38 citations Open access
Semantic Scholar
Murine Coronaviruses Encoding nsp2 at Different Genomic Loci Have Altered Replication, Protein Expression, and Localization
Mark J. Gadlage, R. Graham, M. Denison
2008Journal of Virology35 citations Open access
Semantic Scholar
The NSP2 Proteins of Mouse Hepatitis Virus and Sars Coronavirus are Dispensable for Viral Replication
R. Graham, A. Sims, R. Baric, M. Denison
2006Advances in Experimental Medicine and Biology35 citations Open access
Semantic Scholar
SARS-CoV-2: Combating Coronavirus Emergence
R. Graham, R. Baric
2020Immunity32 citations Open access
Semantic Scholar
Bat Caliciviruses and Human Noroviruses Are Antigenically Similar and Have Overlapping Histo-Blood Group Antigen Binding Profiles
J. Kocher, L. Lindesmith, K. Debbink, A. Beall +7 more
2018mBio32 citations Open access
Semantic Scholar
Expanded subgenomic mRNA transcriptome and coding capacity of a nidovirus
Han Di, Joseph C. Madden, Esther K. Morantz, Hsin-Yao Tang +3 more
2017Proceedings of the National Academy of Sciences of the United States of America32 citations Open access
Semantic Scholar
Coronavirus Replicase-Reporter Fusions Provide Quantitative Analysis of Replication and Replication Complex Formation
M. Freeman, R. Graham, Xiao-Tao Lu, Christopher T. Peek +1 more
2014Journal of Virology31 citations Open access
Semantic Scholar
Human Norovirus Epitope D Plasticity Allows Escape from Antibody Immunity without Loss of Capacity for Binding Cellular Ligands
L. Lindesmith, Paul D. Brewer-Jensen, Michael L. Mallory, B. Yount +4 more
2018Journal of Virology27 citations Open access
Semantic Scholar

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