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A. Hocke · SciRah

Researcher profile · Semantic Scholar

A. Hocke

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A. Hocke — researcher profile on SciRah

h-index: 53
Works: 209
Citations: 12K

Most-cited papers

SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19
Julian Braun, L. Loyal, M. Frentsch, D. Wendisch +29 more
2020Nature1,121 citations Open access
Semantic Scholar
COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis
R. Chua, Soeren Lukassen, S. Trump, Bianca P. Hennig +32 more
2020Nature Biotechnology968 citations Open access
Semantic Scholar
Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment
J. Schulte-Schrepping, N. Reusch, D. Paclik, K. Baßler +128 more
2020Cell658 citations Open access
Semantic Scholar
Ultra-High-Throughput Clinical Proteomics Reveals Classifiers of COVID-19 Infection
C. Messner, Vadim Demichev, D. Wendisch, Laura Michalick +29 more
2020Cell Systems478 citations Open access
Semantic Scholar
SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis
D. Wendisch, Oliver Dietrich, T. Mari, Saskia von Stillfried +58 more
2021Cell447 citations Open access
Semantic Scholar
A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model
J. Kreye, S. Reincke, Hans-Christian Kornau, Elisa Sánchez-Sendín +40 more
2020Cell325 citations Open access
Semantic Scholar
Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination
L. Loyal, Julian Braun, L. Henze, B. Kruse +33 more
2021Science276 citations Open access
Semantic Scholar
SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals
N. Gassen, Jan Papies, T. Bajaj, J. Emanuel +31 more
2021Nature Communications273 citations Open access
Semantic Scholar
Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy
E. Wyler, Kirstin Mösbauer, V. Franke, Asija Diag +24 more
2021iScience218 citations Open access
Semantic Scholar
Morphological and molecular breast cancer profiling through explainable machine learning
A. Binder, M. Bockmayr, Miriam Hägele, S. Wienert +8 more
2021Nature Machine Intelligence155 citations Open access
Semantic Scholar
Optimization of cell-laden bioinks for 3D bioprinting and efficient infection with influenza A virus
J. Berg, T. Hiller, M. Kissner, T. Qazi +7 more
2018Scientific Reports149 citations Open access
Semantic Scholar
Generation of a 3D Liver Model Comprising Human Extracellular Matrix in an Alginate/Gelatin-Based Bioink by Extrusion Bioprinting for Infection and Transduction Studies
T. Hiller, J. Berg, L. Elomaa, Viola Röhrs +10 more
2018International Journal of Molecular Sciences133 citations Open access
Semantic Scholar
Single-cell transcriptomics reveals common epithelial response patterns in human acute kidney injury
C. Hinze, C. Kocks, Janna Leiz, Nikos Karaiskos +22 more
2022Genome Medicine107 citations Open access
Semantic Scholar
Phage capsid nanoparticles with defined ligand arrangement block influenza virus entry
Daniel Lauster, Simon Klenk, Kai Ludwig, Saba Nojoumi +24 more
2020Nature Nanotechnology96 citations
Semantic Scholar
3D organ models—Revolution in pharmacological research?
M. Weinhart, A. Hocke, S. Hippenstiel, J. Kurreck +1 more
2018Pharmacological Research74 citations Open access
Semantic Scholar
A novel European H5N8 influenza A virus has increased virulence in ducks but low zoonotic potential
C. Grund, D. Hoffmann, R. Ulrich, Mahmoud M. Naguib +10 more
2018Emerging Microbes and Infections74 citations Open access
Semantic Scholar
Studying the pathophysiology of coronavirus disease 2019: a protocol for the Berlin prospective COVID-19 patient cohort (Pa-COVID-19)
F. Kurth, M. Roennefarth, C. Thibeault, V. Corman +39 more
2020Infection71 citations Open access
Semantic Scholar
Pneumolysin induced mitochondrial dysfunction leads to release of mitochondrial DNA
A. Nerlich, M. Mieth, E. Letsiou, D. Fatykhova +16 more
2018Scientific Reports58 citations Open access
Semantic Scholar
Studying the pathophysiology of coronavirus disease 2019 - a protocol for the Berlin prospective COVID-19 patient cohort (Pa- COVID-19)
F. Kurth, M. Roennefarth, C. Thibeault, V. Corman +34 more
2020medRxiv54 citations Open access
Semantic Scholar
Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages
Katja Hönzke, B. Obermayer, C. Mache, Diana Fathykova +50 more
2022European Respiratory Journal49 citations Open access
Semantic Scholar
Distinct tissue niches direct lung immunopathology via CCL18 and CCL21 in severe COVID-19
R. Mothes, A. Pascual-Reguant, R. Koehler, J. Liebeskind +28 more
2023Nature Communications48 citations Open access
Semantic Scholar
Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure
Laura Michalick, S. Weidenfeld, Benjamin Grimmer, D. Fatykhova +19 more
2020European Respiratory Journal44 citations Open access
Semantic Scholar
Inhibition of p38 signaling curtails the SARS-CoV-2 induced inflammatory response but retains the IFN-dependent antiviral defense of the lung epithelial barrier
Aileen Faist, S. Schloer, A. Mecate-Zambrano, Josua Janowski +25 more
2022Antiviral Research39 citations Open access
Semantic Scholar
A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model
J. Kreye, S. Reincke, Hans-Christian Kornau, Elisa Sánchez-Sendín +40 more
2020bioRxiv39 citations Open access
Semantic Scholar
Antiviral potential of human IFN-α subtypes against influenza A H3N2 infection in human lung explants reveals subtype-specific activities
A. da Rocha Matos, Katharina Wunderlich, S. Schloer, K. Schughart +17 more
2019Emerging Microbes and Infections39 citations Open access
Semantic Scholar
Photon arrival time tagging with many channels, sub-nanosecond deadtime, very high throughput, and fiber optic remote synchronization.
M. Wahl, T. Röhlicke, Sebastian Kulisch, Sumeet Rohilla +2 more
2020Review of Scientific Instruments37 citations Open access
Semantic Scholar
Suppressive myeloid cells are a hallmark of severe COVID-19
J. Schulte-Schrepping, N. Reusch, D. Paclik, K. Baßler +59 more
2020medRxiv37 citations Open access
Semantic Scholar
Assessing and improving the validity of COVID-19 autopsy studies - A multicentre approach to establish essential standards for immunohistochemical and ultrastructural analyses
S. Krasemann, Carsten Dittmayer, S. von Stillfried, J. Meinhardt +33 more
2022EBioMedicine36 citations Open access
Semantic Scholar
Protein arginine methyltransferase 5 mediates enolase-1 cell surface trafficking in human lung adenocarcinoma cells.
Dariusz Zakrzewicz, M. Didiasova, M. Krüger, B. D. Giaimo +7 more
2018Biochimica et Biophysica Acta - Molecular Basis of Disease36 citations Open access
Semantic Scholar
Bioprinted Multi-Cell Type Lung Model for the Study of Viral Inhibitors
J. Berg, Z. Weber, Mona Fechler-Bitteti, A. Hocke +4 more
2021Viruses31 citations Open access
Semantic Scholar
Preclinical Assessment of Bacteriophage Therapy against Experimental Acinetobacter baumannii Lung Infection
S. Wienhold, M. Brack, G. Nouailles, G. Krishnamoorthy +17 more
2021Viruses30 citations Open access
Semantic Scholar
Towards computational fluorescence microscopy: Machine learning-based integrated prediction of morphological and molecular tumor profiles
Alexander Binder, M. Bockmayr, Miriam Hägele, S. Wienert +14 more
2018arXiv.org28 citations
Semantic Scholar
Collapse induration of alveoli is an ultrastructural finding in a COVID-19 patient
M. Ochs, Sara Timm, S. Elezkurtaj, D. Horst +5 more
2021European Respiratory Journal27 citations Open access
Semantic Scholar
Functional comparison of MERS-coronavirus lineages reveals increased replicative fitness of the recombinant lineage 5
Simon Schroeder, C. Mache, Hannah Kleine-Weber, V. Corman +16 more
2021Nature Communications24 citations Open access
Semantic Scholar
Clinical and virological characteristics of hospitalised COVID-19 patients in a German tertiary care centre during the first wave of the SARS-CoV-2 pandemic: a prospective observational study
C. Thibeault, B. Mühlemann, E. Helbig, M. Mittermaier +139 more
2021Infection24 citations Open access
Semantic Scholar
Human alveolar progenitors generate dual lineage bronchioalveolar organoids
Karen Hoffmann, B. Obermayer, Katja Hönzke, D. Fatykhova +24 more
2022Communications Biology22 citations Open access
Semantic Scholar
SARS-CoV-2 variant Alpha has a spike-dependent replication advantage over the ancestral B.1 strain in human cells with low ACE2 expression
D. Niemeyer, Saskia Stenzel, Talitha Veith, Simon Schroeder +39 more
2022PLoS Biology21 citations Open access
Semantic Scholar
Loss of endothelial CFTR drives barrier failure and edema formation in lung infection and can be targeted by CFTR potentiation
L. Erfinanda, L. Zou, B. Gutbier, L. Kneller +21 more
2022Science Translational Medicine21 citations
Semantic Scholar
Stable integration of the Mrx1-roGFP2 biosensor to monitor dynamic changes of the mycothiol redox potential in Corynebacterium glutamicum
Tung Ngoc Quach, Loi Van Vu, T. Busche, A. Nerlich +5 more
2018Redox Biology20 citations Open access
Semantic Scholar
COVID-19 highlights the model dilemma in biomedical research
P. Adhikary, Qurrat Ul Ain, A. Hocke, S. Hedtrich
2021Nature Reviews Materials19 citations Open access
Semantic Scholar
Cross-talk between the airway epithelium and activated immune cells defines severity in COVID-19
R. Chua, Soeren Lukassen, S. Trump, Bianca P. Hennig +28 more
2020medRxiv18 citations Open access
Semantic Scholar
Bat-borne H9N2 influenza virus evades MxA restriction and exhibits efficient replication and transmission in ferrets
N. Halwe, Lea Hamberger, J. Sehl-Ewert, C. Mache +24 more
2024Nature Communications17 citations Open access
Semantic Scholar
Sphingosine Kinase 1 Regulates Inflammation and Contributes to Acute Lung Injury in Pneumococcal Pneumonia via the Sphingosine-1-Phosphate Receptor 2
B. Gutbier, Stefanie M. Schönrock, Carolin Ehrler, R. Haberberger +22 more
2018Critical Care Medicine17 citations Open access
Semantic Scholar
Long-Term Culture of Distal Airway Epithelial Cells Allows Differentiation Towards Alveolar Epithelial Cells Suited for Influenza Virus Studies
Aki Imai-Matsushima, Laura Martin-Sancho, A. Karlas, Seiichiro Imai +5 more
2018EBioMedicine17 citations Open access
Semantic Scholar
Clinical classifiers of COVID-19 infection from novel ultra-high-throughput proteomics
C. Messner, Vadim Demichev, D. Wendisch, Laura Michalick +28 more
2020medRxiv14 citations Open access
Semantic Scholar
Targeted small molecule inhibitors blocking the cytolytic effects of pneumolysin and homologous toxins
Umer Aziz, A. Saoud, M. Bermudez, Maren Mieth +10 more
2024Nature Communications13 citations Open access
Semantic Scholar
Multi-target immunofluorescence by separation of antibody cross-labelling via spectral-FLIM-FRET
Sumeet Rohilla, B. Krämer, F. Koberling, I. Gregor +1 more
2020Scientific Reports12 citations Open access
Semantic Scholar
Digital Image Analyses on Whole‐Lung Slides in Mouse Models of Acute Pneumonia
K. Dietert, G. Nouailles, B. Gutbier, K. Reppe +9 more
2018American Journal of Respiratory Cell and Molecular Biology11 citations
Semantic Scholar
VoltRon: A Spatial Omics Analysis Platform for Multi-Resolution and Multi-omics Integration using Image Registration
A. Manukyan, Ella Bahry, E. Wyler, Erik Becher +12 more
2023bioRxiv10 citations Open access
Semantic Scholar
Transcriptomic comparison of primary human lung cells with lung tissue samples and the human A549 lung cell line highlights cell type specific responses during infections with influenza A virus
W. Bertrams, Katja Hönzke, B. Obermayer, M. Tönnies +12 more
2022Scientific Reports10 citations Open access
Semantic Scholar

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