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Chenyi Xue · SciRah

Researcher profile · Semantic Scholar

Chenyi Xue

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Chenyi Xue — researcher profile on SciRah

h-index: 27
Works: 77
Citations: 3,012

Most-cited papers

Single-cell genomics reveals a novel cell state during smooth muscle cell phenotypic switching and potential therapeutic targets for atherosclerosis in mouse and human
Huize Pan, Chenyi Xue, Benjamin J. Auerbach, Jiaxin Fan +18 more
2020Circulation496 citations Open access
Semantic Scholar
The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis
T. Fidler, Chenyi Xue, M. Yalçınkaya, Brian D. Hardaway +22 more
2021Nature434 citations Open access
Semantic Scholar
Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1
Anne M. Curtis, C. T. Fagundes, Guangrui Yang, E. Pålsson-McDermott +14 more
2015Proceedings of the National Academy of Sciences of the United States of America306 citations Open access
Semantic Scholar
Loss-of-Function Mutations in APOC3, Triglycerides, and Coronary Disease
Jacy R. Crosby, G. Peloso, P. Auer, D. Crosslin +82 more
2014New England Journal of Medicine253 citations Open access
Semantic Scholar
Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol.
Leslie A. Lange, Youna Hu, He Zhang, Chenyi Xue +98 more
2014American Journal of Human Genetics219 citations Open access
Semantic Scholar
Functional Analysis and Transcriptomic Profiling of iPSC-derived Macrophages and Their Application in Modeling Mendelian Disease
Han-Rui Zhang, Chenyi Xue, Rhia Y. Shah, Kate Bermingham +18 more
2015Circulation Research125 citations Open access
Semantic Scholar
High-Dimensional Single-Cell Multimodal Landscape of Human Carotid Atherosclerosis
A. Bashore, Hanying Yan, Chenyi Xue, Lucie Y Zhu +12 more
2023medRxiv96 citations Open access
Semantic Scholar
Tissue-specific RNA-Seq in Human Evoked Inflammation Identifies Blood and Adipose LincRNA Signatures of Cardio-metabolic Diseases
Yi-Chuan Liu, Jane F. Ferguson, Chenyi Xue, Rachel L Ballantyne +7 more
2014Arteriosclerosis, Thrombosis and Vascular Biology77 citations Open access
Semantic Scholar
The long noncoding RNA landscape in hypoxic and inflammatory renal epithelial injury.
Jennie Lin, Xuan Zhang, Chenyi Xue, Han-Rui Zhang +11 more
2015AJP - Renal Physiology76 citations Open access
Semantic Scholar
Evaluating the Impact of Sequencing Depth on Transcriptome Profiling in Human Adipose
Yi-Chuan Liu, Jane F. Ferguson, Chenyi Xue, I. Silverman +3 more
2013PLoS ONE76 citations Open access
Semantic Scholar
ASEP: Gene-based detection of allele-specific expression across individuals in a population by RNA sequencing
Jiaxin Fan, Jian Hu, Chenyi Xue, Han-Rui Zhang +4 more
2020PLoS Genetics67 citations Open access
Semantic Scholar
Atherosclerosis is a smooth muscle cell-driven tumor-like disease
Huize Pan, Sebastian E. Ho, Chenyi Xue, Jian Cui +5 more
2023bioRxiv62 citations Open access
Semantic Scholar
Interrogation of nonconserved human adipose lincRNAs identifies a regulatory role of linc-ADAL in adipocyte metabolism
Xuan Zhang, Chenyi Xue, Jennie Lin, Jane F. Ferguson +15 more
2018Science Translational Medicine58 citations Open access
Semantic Scholar
A functional synonymous coding variant in the IL1RN gene is associated with survival in septic shock.
N. Meyer, Jane F. Ferguson, R. Feng, Fan Wang +10 more
2014American Journal of Respiratory and Critical Care Medicine45 citations Open access
Semantic Scholar
Distinct Functions of PPARγ Isoforms in Regulating Adipocyte Plasticity
Dylan Li, Feng Zhang, Xuan Zhang, Chenyi Xue +5 more
2016Biochemical and Biophysical Research Communications - BBRC43 citations Open access
Semantic Scholar
Deep RNA Sequencing Uncovers a Repertoire of Human Macrophage Long Intergenic Noncoding RNAs Modulated by Macrophage Activation and Associated With Cardiometabolic Diseases
Han-Rui Zhang, Chenyi Xue, Ying Wang, Jianting Shi +11 more
2017Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease42 citations Open access
Semantic Scholar
A genome-wide CRISPR screen identifies WDFY3 as a regulator of macrophage efferocytosis
Jianting Shi, Xun Wu, Ziyi Wang, Fang Li +12 more
2022Nature Communications39 citations Open access
Semantic Scholar
Deficiency of macrophage PHACTR1 impairs efferocytosis and promotes atherosclerotic plaque necrosis.
Canan Kasikara, M. Schilperoort, Brennan D. Gerlach, Chenyi Xue +9 more
2021Journal of Clinical Investigation39 citations Open access
Semantic Scholar
Genome-wide interrogation reveals hundreds of long intergenic noncoding RNAs that associate with cardiometabolic traits.
Rachel L Ballantyne, Xuan Zhang, Sara Nuñez, Chenyi Xue +6 more
2016Human Molecular Genetics39 citations Open access
Semantic Scholar
Transcriptome-Wide Analysis Reveals Modulation of Human Macrophage Inflammatory Phenotype Through Alternative Splicing
Jennie Lin, Yu Hu, Sara Nuñez, A. Foulkes +9 more
2016Arteriosclerosis, Thrombosis and Vascular Biology39 citations Open access
Semantic Scholar
PennSeq: accurate isoform-specific gene expression quantification in RNA-Seq by modeling non-uniform read distribution
Yu Hu, Yi-Chuan Liu, Xianyun Mao, Cheng Jia +5 more
2013Nucleic Acids Research39 citations Open access
Semantic Scholar
Why Does the Giant Panda Eat Bamboo? A Comparative Analysis of Appetite-Reward-Related Genes among Mammals
Ke Jin, Chenyi Xue, Xiaoli Wu, Jinyi Qian +8 more
2011PLoS ONE35 citations Open access
Semantic Scholar
NuSAP governs chromosome oscillation by facilitating the Kid-generated polar ejection force
Chenyu Li, Chenyi Xue, Qiaoyun Yang, B. C. Low +1 more
2016Nature Communications32 citations Open access
Semantic Scholar
CRISPR/Cas9-mediated gene editing in human iPSC-derived macrophage reveals lysosomal acid lipase function in human macrophages
Han-Rui Zhang, Jianting Shi, Mélanie Hachet, Chenyi Xue +10 more
2017Arteriosclerosis, Thrombosis and Vascular Biology30 citations Open access
Semantic Scholar
Expression of Calgranulin Genes S100A8, S100A9 and S100A12 Is Modulated by n-3 PUFA during Inflammation in Adipose Tissue and Mononuclear Cells
Rachana Shah, Chenyi Xue, Han-Rui Zhang, S. Tuteja +3 more
2017PLoS ONE30 citations Open access
Semantic Scholar
Effect of mechanical unloading on genome-wide DNA methylation profile of the failing human heart
Xianghai Liao, Peter J. Kennel, Bo-Hao Liu, Trevor R. Nash +10 more
2023JCI Insight29 citations Open access
Semantic Scholar
Adipose tissue RNASeq reveals novel gene-nutrient interactions following n-3 PUFA supplementation and evoked inflammation in humans
Jane F. Ferguson, Chenyi Xue, Yu Hu, Ming-Yao Li +1 more
2016Journal of Nutritional Biochemistry28 citations Open access
Semantic Scholar
Differentiation of Human-Induced Pluripotent Stem Cells to Macrophages for Disease Modeling and Functional Genomics
Jianting Shi, Chenyi Xue, Wen Liu, Han-Rui Zhang
2018Current protocols in stem cell biology26 citations Open access
Semantic Scholar
The activity and expression of microRNAs in prostate cancers.
Xu-Ping Fu, Chenyi Xue, Yan Huang, Yi Xie +1 more
2010Molecular Biosystems24 citations
Semantic Scholar
Common and Rare Genetic Variation in CCR2, CCR5, or CX3CR1 and Risk of Atherosclerotic Coronary Heart Disease and Glucometabolic Traits
J. Golbus, N. Stitziel, Wei Zhao, Chenyi Xue +10 more
2016Circulation: Cardiovascular Genetics20 citations Open access
Semantic Scholar
Integrative genomics identifies 7p11.2 as a novel locus for fever and clinical stress response in humans.
Jane F. Ferguson, N. Meyer, L. Qu, Chenyi Xue +9 more
2015Human Molecular Genetics20 citations Open access
Semantic Scholar
Racial differences in MLH1 and MSH2 mutation: an analysis of yellow race and white race based on the InSiGHT database.
Wenqian Wei, Lei Liu, Jian Chen, Ke Jin +9 more
2010Journal of Bioinformatics and Computational Biology16 citations
Semantic Scholar
Single-cell multimodal profiling of atherosclerosis identifies CD200 as a cell surface lineage marker of vascular smooth muscle cells and their derived cells
A. Bashore, Allen Chung, Chinyere O. Ibikunle, Han-Ying Yan +4 more
2023bioRxiv11 citations Open access
Semantic Scholar
linc-ADAIN, a human adipose lincRNA, regulates adipogenesis by modulating KLF5 and IL-8 mRNA stability
M. O'Reilly, Sebastian E. Ho, Johana Coronel, Lucie Y. Zhu +14 more
2024Cell Reports9 citations Open access
Semantic Scholar
Adipocyte-specific tribbles pseudokinase 1 regulates plasma adiponectin and plasma lipids in mice
Elizabeth E. Ha, G. Quartuccia, Ruifeng Ling, Chenyi Xue +11 more
2021Molecular Metabolism9 citations Open access
Semantic Scholar
Tissue-specific Differential Expression of Novel Genes and Long Intergenic Non-coding RNAs in Humans with Extreme Response to Evoked Endotoxemia
Jane F. Ferguson, Chenyi Xue, Yuan-Feng Gao, Tian Tian +8 more
2018Circulation Genomic and Precision Medicine8 citations Open access
Semantic Scholar
De novo RNA sequence assembly during in vivo inflammatory stress reveals hundreds of unannotated lincRNAs in human blood CD14+ monocytes and in adipose tissue.
Chenyi Xue, Xuan Zhang, Han-Rui Zhang, Jane F. Ferguson +4 more
2017Physiological Genomics8 citations Open access
Semantic Scholar
Non-conserved lincRNAs associate with complex cardiometabolic disease traits
A. Foulkes, Caitlin A. Selvaggi, Ting-Yi Cao, M. O'Reilly +5 more
2020Arteriosclerosis, Thrombosis and Vascular Biology7 citations Open access
Semantic Scholar
Decoding the Variant-to-Function Relationship for LIPA , a Risk Locus for CAD
Fang Li, Elise D. Flynn, Jianting Shi, Xun Wu +16 more
20223 citations
Semantic Scholar
Cis-regulated expression of non-conserved lincRNAs associates with cardiometabolic related traits
Ting-Yi Cao, M. O'Reilly, Caitlin A. Selvaggi, E. Cynn +5 more
2022Journal of Human Genetics3 citations Open access
Semantic Scholar
Retinoic acid signaling modulates smooth muscle cell phenotypic switching in atherosclerosis through epigenetic regulation of gene expression
Huize Pan, Sebastian E. Ho, Chenyi Xue, Jian Cui +2 more
2022bioRxiv2 citations Open access
Semantic Scholar
A Genome-wide CRISPR Screen Identifies WDFY3 as a Novel Regulator of Macrophage Efferocytosis
Jianting Shi, Xun Wu, Zi-Yi Wang, Fang Li +12 more
2022bioRxiv1 citations Open access
Semantic Scholar
Genome-Wide DNA Methylation Profiling of the Failing Human Heart with Mechanical Unloading Identifies LINC00881 as an Essential Regulator of Calcium Handling in the Cardiomyocyte
Xianghai Liao, Peter J. Kennel, Bo-Hao Liu, Trevor R. Nash +10 more
2022bioRxiv1 citations Open access
Semantic Scholar
Adipocyte Tribbles1 Regulates Plasma Adiponectin and Plasma Lipids in Mice
Elizabeth E. Ha, G. Quartuccia, Ruifeng Ling, Chenyi Xue +5 more
2021bioRxiv1 citations Open access
Semantic Scholar
Single-cell multimodal profiling of monocytes reveals diverse phenotypes and alterations linked to cardiovascular disease risks
A. Bashore, Chenyi Xue, Eunyoung Kim, Han-Ying Yan +7 more
2024bioRxiv0 citations Open access
Semantic Scholar
Abstract 720: Integration Of Population Genetic And Human Knockout Studies With Smooth Muscle Cell Lineage Tracing In Mouse Models Identifies Novel Targets For Atherosclerosis And Cardiovascular Risk.
Thomas Mawson, S. Khalid, Chen Wang, Leila S. Ross +4 more
2023Arteriosclerosis, Thrombosis and Vascular Biology0 citations
Semantic Scholar
Abstract 108: Il-1β Inhibition Promotes Fibrous Cap Thickening and Accumulation of Fibroblast Like Cells in Atheromas in Clonal Hematopoiesis
Trevor P. Fidler, Eunyoung Kim, Brian D. Hardaway, Chenyi Xue +5 more
2023Arteriosclerosis, Thrombosis and Vascular Biology0 citations
Semantic Scholar
Abstract 701: Atherosclerosis Is A Smooth Muscle Cell-driven Tumor-like Disease
Huize Pan, Sebastian E. Ho, Chenyi Xue, Jian Cui +3 more
2023Arteriosclerosis, Thrombosis and Vascular Biology0 citations
Semantic Scholar
Abstract 212: Transcriptional Profiling Of Vascular Smooth Muscle Cell-foam Cells In Atherosclerotic Lesions
Chinyere O. Ibikunle, A. Bashore, Huize Pan, Chenyi Xue +3 more
2023Arteriosclerosis, Thrombosis and Vascular Biology0 citations
Semantic Scholar
Abstract 490: High-dimensional Proteogenomics Of Human Carotid Atherosclerosis Reveals Significant Diversity Of Smooth Muscle Cells Within Plaques
A. Bashore, Han-Ying Yan, Chenyi Xue, Lucie Y. Zhu +3 more
2023Arteriosclerosis, Thrombosis and Vascular Biology0 citations
Semantic Scholar

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