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J. L. Jacot · SciRah

Researcher profile · Semantic Scholar

J. L. Jacot

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J. L. Jacot — researcher profile on SciRah

h-index: 10
Works: 32
Citations: 563

Most-cited papers

Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications.
M. V. Van Zandt, Michael L. Jones, David E. Gunn, Leo S. Geraci +8 more
2005Journal of Medicinal Chemistry202 citations Open access
Semantic Scholar
Potential Therapeutic Roles for Inhibition of the PI3K/Akt/mTOR Pathway in the Pathophysiology of Diabetic Retinopathy
J. L. Jacot, D. Sherris
2011Journal of Ophthalmology91 citations Open access
Semantic Scholar
Sorbinil prevention of diabetic-like retinopathy in the galactose-fed rat model.
W. Robison, N. Laver, J. L. Jacot, J. Glover
1995Investigative Ophthalmology and Visual Science50 citations
Semantic Scholar
Diabetic-like retinopathy ameliorated with the aldose reductase inhibitor WAY-121,509.
W. G. Robinson, Nora Laver, J. L. Jacot, J. Glover +3 more
1996Investigative Ophthalmology and Visual Science36 citations
Semantic Scholar
Retinal Vascular Changes Induced by the Oxidative Stress of α-Tocopherol Deficiency Contrasted with Diabetic Microangiopathy
W. Robison, J. L. Jacot, M. L. Katz, J. P. Glover
200034 citations
Semantic Scholar
Nitric Oxide Modulation of Retinal, Choroidal, and Anterior Uveal Blood Flow in Newborn Piglets
J. L. Jacot, J. O'Neill, Debbie M. Scandling, S. D. West +1 more
1998Journal of Ocular Pharmacology and Therapeutics32 citations
Semantic Scholar
Diabetic-like retinopathy: early and late intervention therapies in galactose-fed rats.
W. Robison, J. L. Jacot, J. Glover, M. Basso +1 more
1998Investigative Ophthalmology and Visual Science27 citations
Semantic Scholar
Diabetic-like Corneal Sensitivity Loss in Galactose-Fed Rats Ameliorated with Aldose Reductase Inhibitors
J. L. Jacot, H. Hosotani, J. P. Glover, N. Lois +1 more
1998Journal of Ocular Pharmacology and Therapeutics23 citations
Semantic Scholar
Computer analysis of corneal innervation density using a novel double stain in rat corneal whole mounts
J. L. Jacot, J. P. Glover, W. Robison
1997Journal of Anatomy18 citations Open access
Semantic Scholar
Efficacy of treatment after measurable diabeticlike retinopathy in galactose-fed rats.
W. Robison, Nora Laver, J. L. Jacot, M. Chandler +2 more
1997Investigative Ophthalmology and Visual Science15 citations
Semantic Scholar
Retinal Capillary Dilation: Early Diabetic-Like Retinopathy in the Galactose-Fed Rat Model
J. P. Glover, J. L. Jacot, Michael D. Basso, T. Hohman +1 more
2000Journal of Ocular Pharmacology and Therapeutics7 citations
Semantic Scholar
Emerging therapeutics for diabetic retinopathy: potential therapies for the new millennium
J. L. Jacot, J. Sredy
19997 citations
Semantic Scholar
Improved gold chloride procedure for nerve staining in whole mounts of rat corneas.
J. L. Jacot, J. P. Glover, W. Robison
1995Biotechnic & Histochemistry7 citations
Semantic Scholar
Histological evaluation of the canine retinal vasculature following chronic systemic administration of basic fibroblast growth factor.
J. L. Jacot, Nora Laver, J. Glover, D. F. Lazarous +2 more
1996Journal of Anatomy5 citations
Semantic Scholar
Retinal vascular changes induced by the oxidative stress of alpha-tocopherol deficiency contrasted with diabetic microangiopathy.
W. Robison, J. L. Jacot, M. L. Katz, J. P. Glover
2000Journal of Ocular Pharmacology and Therapeutics4 citations
Semantic Scholar
Diabetic Retinopathy: Unraveling the Paradoxical Effects of Intensive Insulin Treatment
J. L. Jacot, A. Vinik
20072 citations
Semantic Scholar
Azithromycin Alters ProMMP-2 and TIMP-1 Following Corneal Wounding in an Experimental Animal Model of Diabetic Ocular Complications
J. L. Jacot, T. Jacot, S. Hahto, J. Helis +4 more
20091 citations
Semantic Scholar
Human aldose reductase in complex with NADP+ and the inhibitor lidorestat at 1.04 angstrom
M. V. Van Zandt, Michael L. Jones, David E. Gunn, L. Geraci +8 more
20061 citations
Semantic Scholar
Glycation of lens proteins in relation to aldose reductase activity and galactose-induced cataracts
J. Glover, J. L. Jacot, C. Rao, C. Qin +2 more
19961 citations
Semantic Scholar
The Vasoproliferative Phase in the Oxygen-Induced Rat Model ofRetinopathy of Prematurity Exhibits Concomitant Increased Expression ofVEGF164 and Phosphorylation of eNOS at Serine1179.
J. L. Jacot, R. Looft-Wilson, Nazita Yousefieh, F. Lattanzio +1 more
20170 citations
Semantic Scholar
Expression of eNOS and VEGF in Normoxia Mediated Vasculopathy in Rat Retinopathy of Prematurity Model
A. Hosseini, F. Lattanzio, Nazita Yousefieh, R. Wade +1 more
20130 citations
Semantic Scholar
Evaluation Of Anti-tubulin Agents For The Prevention Of Vasculopathy In A Rat Model Of Retinopathy Of Prematurity
A. Hosseini, J. L. Jacot, F. Lattanzio, K. Schellenberg +2 more
20110 citations
Semantic Scholar
Evaluation of Progression and Topographical Juxtaposition of Retinopathy and Choriopathy in the Galactosemic Rat Model by Confocal Microscopy
F. Lattanzio, S. Hahto, S. Helke, C. Sheppard +1 more
20090 citations
Semantic Scholar
Expression of BFGF and IL-1 Alpha in Tears of Galactosemic Rats: Implications for Wound Healing and Neovascularization
M. Wertheimer, J. Helis, S. Hahto, J. Sheppard +4 more
20090 citations
Semantic Scholar
Recent contributions of animal models for elucidating ocular complications of diabetes
W. Robison, J. L. Jacot, J. P. Glover
20090 citations
Semantic Scholar
Absence of Adverse Effects Following 6 Months Topical Application of OC-10X
Patricia B. Williams, F. Lattanzio, S. Samudre, A. Hosseini +2 more
20090 citations
Semantic Scholar
Evaluation of MMP2/9 Modulation by Azithromycin and DuraSite on Human Corneal Epithelial Cells and Bovine Corneal Endothelial Cells in vitro
J. L. Jacot, T. Jacot, J. Sheppard, F. Lattanzio +2 more
20080 citations
Semantic Scholar
Antihypertriglyceridemische, antihyperglykemische, antiangiogenic and wound-healing substituted indolalkansäure
J. L. Jacot, J. Sredy
19990 citations
Semantic Scholar
Diabetic-like loss of corneal sensitivity in the 50% galactose fed rat is ameliorated with topical administration of an aldose reductase inhibitor
J. L. Jacot, J. Glover, W. Robison, H. Hosotani +1 more
19960 citations
Semantic Scholar
P 155 Decreased central corneal sensitivity in the 50% galactose-FED rat model of diabetic ocular complications
J. L. Jacot, N. Lois, J. Glover, W. Robison
19950 citations Open access
Semantic Scholar
Absence of retinal neovascularization following chronic, systemic basic fibroblast growth factor administration
N. Laver, J. L. Jacot, J. Glover, D. F. Lazarous +3 more
19950 citations
Semantic Scholar
The Role of Nitric Oxide in Modulating Retinal, Choroidal, and Anterior Uveal Blood Flows in the Domestic Piglet
J. L. Jacot
19930 citations
Semantic Scholar

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F. Lattanzio×8
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Patricia B. Williams

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