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J. Sheppard · SciRah

Researcher profile · Semantic Scholar

J. Sheppard

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J. Sheppard — researcher profile on SciRah

h-index: 32
Works: 130
Citations: 3,500

Most-cited papers

Adalimumab for prevention of uveitic flare in patients with inactive non-infectious uveitis controlled by corticosteroids (VISUAL II): a multicentre, double-masked, randomised, placebo-controlled phase 3 trial.
Q. Nguyen, P. Merrill, G. Jaffe, A. Dick +12 more
2016The Lancet493 citations Open access
Semantic Scholar
Ocular TRUST: nationwide antimicrobial susceptibility patterns in ocular isolates.
P. Asbell, K. Colby, Sophie X. Deng, P. Mcdonnell +4 more
2008American journal of ophthalmology-glaucoma235 citations
Semantic Scholar
Lifitegrast ophthalmic solution 5.0% for treatment of dry eye disease: results of the OPUS-1 phase 3 study.
J. Sheppard, G. Torkildsen, John D Lonsdale, F. D'Ambrosio +4 more
2014Ophthalmology (Rochester, Minn.)223 citations
Semantic Scholar
Dry eye disease: identification and therapeutic strategies for primary care clinicians and clinical specialists
J. Sheppard, Bridgitte Shen Lee, L. Periman
2022Annals medicus182 citations Open access
Semantic Scholar
Dry Eye Disease Associated with Meibomian Gland Dysfunction: Focus on Tear Film Characteristics and the Therapeutic Landscape
J. Sheppard, Kelly K. Nichols
2023Ophthalmology and Therapy163 citations Open access
Semantic Scholar
Impact of the Topical Ophthalmic Corticosteroid Loteprednol Etabonate on Intraocular Pressure
J. Sheppard, T. Comstock, M. Cavet
2016Advances in Therapy116 citations Open access
Semantic Scholar
A Phase 3, Randomized, Double-Masked Study of OTX-101 Ophthalmic Solution 0.09% in the Treatment of Dry Eye Disease.
D. Goldberg, R. Malhotra, B. Schechter, A. Justice +2 more
2019Ophthalmology (Rochester, Minn.)107 citations Open access
Semantic Scholar
Long-term Supplementation With n-6 and n-3 PUFAs Improves Moderate-to-Severe Keratoconjunctivitis Sicca: A Randomized Double-Blind Clinical Trial
J. Sheppard, Ruhi Singh, A. McClellan, Mitchell P. Weikert +5 more
2013Cornea82 citations
Semantic Scholar
Topical Loteprednol Pretreatment Reduces Cyclosporine Stinging in Chronic Dry Eye Disease
J. Sheppard, S. Scoper, S. Samudre
2011Journal of Ocular Pharmacology and Therapeutics82 citations
Semantic Scholar
Effect of Adalimumab on Visual Functioning in Patients With Noninfectious Intermediate Uveitis, Posterior Uveitis, and Panuveitis in the VISUAL-1 and VISUAL-2 Trials
J. Sheppard, A. Joshi, K. Betts, S. Hudgens +4 more
2017JAMA ophthalmology75 citations Open access
Semantic Scholar
Effect of Loteprednol Etabonate 0.5% on Initiation of Dry Eye Treatment With Topical Cyclosporine 0.05%
J. Sheppard, E. Donnenfeld, E. Holland, C. Slonim +7 more
2014Eye & contact lens75 citations
Semantic Scholar
Lacritin, a novel human tear glycoprotein, promotes sustained basal tearing and is well tolerated.
S. Samudre, F. Lattanzio, V. Lossen, A. Hosseini +4 more
2011Investigative Ophthalmology and Visual Science75 citations Open access
Semantic Scholar
Difluprednate 0.05% versus prednisolone acetate 1% for endogenous anterior uveitis: a phase III, multicenter, randomized study.
J. Sheppard, M. Toyos, J. Kempen, P. Kaur +1 more
2014Investigative Ophthalmology and Visual Science65 citations Open access
Semantic Scholar
Hypotony in Patients with Uveitis: The Multicenter Uveitis Steroid Treatment (MUST) Trial
H. Sen, Lea T. Drye, D. Goldstein, T. Larson +6 more
2012Ocular immunology and inflammation65 citations Open access
Semantic Scholar
Efficacy and Safety of a Water-Free Topical Cyclosporine, 0.1%, Solution for the Treatment of Moderate to Severe Dry Eye Disease
E. Akpek, D. Wirta, Johnathon Downing, J. Tauber +4 more
2023JAMA ophthalmology64 citations Open access
Semantic Scholar
A Water-free 0.1% Cyclosporine A Solution for Treatment of Dry Eye Disease: Results of the Randomized Phase 2B/3 ESSENCE Study
J. Sheppard, D. Wirta, E. McLaurin, Blair Boehmer +6 more
2021Cornea54 citations Open access
Semantic Scholar
NOV03 for Signs and Symptoms of Dry Eye Disease Associated With Meibomian Gland Dysfunction: the Randomized Phase 3 MOJAVE Study: NOV03 for Dry Eye Disease Associated With Meibomian Gland Dysfunction (69 characters; limit, 60).
J. Sheppard, F. Kurata, Alice T. Epitropoulos, S. Krösser +1 more
2023American journal of ophthalmology-glaucoma50 citations Open access
Semantic Scholar
Adenovirus Ocular Infections: Prevalence, Pathology, Pitfalls, and Practical Pointers.
D. Garcia-Zalisnak, C. Rapuano, J. Sheppard, A. R. Davis
2018Eye & contact lens49 citations
Semantic Scholar
Loteprednol etabonate for inflammatory conditions of the anterior segment of the eye: twenty years of clinical experience with a retrometabolically designed corticosteroid
T. Comstock, J. Sheppard
2018Expert Opinion on Pharmacotherapy45 citations Open access
Semantic Scholar
TFOS lifestyle: Impact of nutrition on the ocular surface.
Maria Markoulli, J. Arcot, Sumayya Ahmad, R. Arita +15 more
2023The ocular surface44 citations Open access
Semantic Scholar
Topical bromfenac for prevention and treatment of cystoid macular edema following cataract surgery: a review
J. Sheppard
2016Clinical Ophthalmology41 citations Open access
Semantic Scholar
Characterization of tear production in subjects with dry eye disease during intranasal tear neurostimulation: Results from two pivotal clinical trials.
J. Sheppard, G. Torkildsen, Joel A. Geffin, Dao Jung +6 more
2019The ocular surface38 citations Open access
Semantic Scholar
A Randomized Double-Masked Phase 2a Trial to Evaluate Activity and Safety of Topical Ocular Reproxalap, a Novel RASP Inhibitor, in Dry Eye Disease
D. Clark, J. Sheppard, T. Brady
2021Journal of Ocular Pharmacology and Therapeutics37 citations Open access
Semantic Scholar
Herpes Zoster Ophthalmicus Review and Prevention.
A. R. Davis, J. Sheppard
2019Eye & contact lens37 citations
Semantic Scholar
An update on the surgical management of pterygium and the role of loteprednol etabonate ointment
J. Sheppard, A. Mansur, T. Comstock, J. Hovanesian
2014Clinical Ophthalmology36 citations Open access
Semantic Scholar
Early Onset and Broad Activity of Reproxalap in a Randomized, Double-Masked, Vehicle-Controlled Phase 2b Trial in Dry Eye Disease.
D. Clark, J. Tauber, J. Sheppard, T. Brady
2021American journal of ophthalmology-glaucoma35 citations Open access
Semantic Scholar
Antibiotic resistance in acute postoperative endophthalmitis.
E. Holland, M. McDonald, J. G. Parekh, J. Sheppard
2014Ophthalmology (Rochester, Minn.)35 citations
Semantic Scholar
Intracameral phenylephrine and ketorolac during cataract surgery to maintain intraoperative mydriasis and reduce postoperative ocular pain: Integrated results from 2 pivotal phase 3 studies
J. Hovanesian, J. Sheppard, W. Trattler, J. Gayton +4 more
2015Journal of cataract and refractive surgery32 citations Open access
Semantic Scholar
Azelastine hydrochloride, a dual-acting anti-inflammatory ophthalmic solution, for treatment of allergic conjunctivitis
Patricia B. Williams, Elizabeth Crandall, J. Sheppard
2010Clinical Ophthalmology31 citations Open access
Semantic Scholar
Emerging therapies for dry eye disease
Lauren Mason, Saad Jafri, Isabelle Dortonne, J. Sheppard
2021Expert Opinion on Emerging Drugs23 citations
Semantic Scholar
Difluprednate 0.05% versus Prednisolone Acetate 1% for Endogenous Anterior Uveitis: Pooled Efficacy Analysis of Two Phase 3 Studies
J. Sheppard, C. S. Foster, M. Toyos, K. Markwardt +3 more
2019Ocular immunology and inflammation23 citations Open access
Semantic Scholar
Randomized Phase 2 Trial of Reproxalap, a Novel Reactive Aldehyde Species Inhibitor, in Patients with Noninfectious Anterior Uveitis: Model for Corticosteroid Replacement
K. Mandell, D. Clark, David S. Chu, C. S. Foster +2 more
2020Journal of Ocular Pharmacology and Therapeutics22 citations Open access
Semantic Scholar
Efficacy and Safety of OTX-101, a Novel Nanomicellar Formulation of Cyclosporine A, for the Treatment of Keratoconjunctivitis Sicca: Pooled Analysis of a Phase 2b/3 and Phase 3 Study.
J. Sheppard, Shane R. Kannarr, J. Luchs, R. Malhotra +4 more
2019Eye & contact lens22 citations
Semantic Scholar
Selective Pharmacologic Therapies for Dry Eye Disease Treatment: Efficacy, Tolerability, and Safety Data Review from Preclinical Studies and Pivotal Trials
Bridgitte Shen Lee, M. Toyos, P. Karpecki, Jesse Schiffbauer +1 more
2022Ophthalmology and Therapy21 citations Open access
Semantic Scholar
Clinically Relevant Activity of the Novel RASP Inhibitor Reproxalap in Allergic Conjunctivitis: The Phase 3 ALLEVIATE Trial.
D. Clark, B. Cavanagh, A. Shields, P. Karpecki +2 more
2021American journal of ophthalmology-glaucoma21 citations Open access
Semantic Scholar
Multicenter Study of a Novel Topical Interleukin-1 Receptor Inhibitor, Isunakinra, in Subjects With Moderate to Severe Dry Eye Disease
M. Goldstein, Joseph R. Martel, K. Sall, D. Goldberg +8 more
2017Eye & contact lens21 citations
Semantic Scholar
Modalities to decrease stromal herpes simplex keratitis reactivation rates.
J. Sheppard, M. Wertheimer, S. Scoper
2009A M A Archives of Ophthalmology21 citations
Semantic Scholar
Current and Future Pharmacological Therapies for the Management of Dry Eye.
Preeya K. Gupta, P. Asbell, J. Sheppard
2020Eye & contact lens20 citations Open access
Semantic Scholar
In Vivo Pharmacokinetics of Bromfenac Ophthalmic Solution 0.075%, Bromfenac Ophthalmic Solution 0.07%, and Nepafenac/Amfenac Ophthalmic Suspension 0.3% in Rabbits
J. Sheppard, P. Cockrum, A. Justice, M. Jasek
2018Ophthalmology and Therapy18 citations Open access
Semantic Scholar
Phase 2, Randomized, Open-Label Parallel-Group Study of Two Dosing Regimens of Netarsudil for the Treatment of Corneal Edema Due to Fuchs Corneal Dystrophy
R. Lindstrom, Amber E. Lewis, E. Holland, J. Sheppard +3 more
2022Journal of Ocular Pharmacology and Therapeutics17 citations Open access
Semantic Scholar
Efficacy of a Phosphorodiamidate Morpholino Oligomer Antisense Compound in the Inhibition of Corneal Transplant Rejection in a Rat Cornea Transplant Model
A. Hosseini, F. Lattanzio, S. Samudre, G. DiSandro +2 more
2012Journal of Ocular Pharmacology and Therapeutics16 citations
Semantic Scholar
Comparison of Persistent Epithelial Defect Treatment with Sutureless Cryopreserved and Dehydrated Amniotic Membrane.
Shawn Sell, Martin de la Presa, Shambhawi Thakur, Medi Eslani +4 more
2022American journal of ophthalmology-glaucoma15 citations
Semantic Scholar
A phase 2 randomized, double-masked, placebo-controlled study of novel nonsystemic kinase inhibitor TOP1630 for the treatment of dry eye disease
Mike Taylor, G. Ousler, G. Torkildsen, C. Walshe +5 more
2019Clinical Ophthalmology15 citations Open access
Semantic Scholar
Post-cataract outcomes in patients with noninfectious posterior uveitis treated with the fluocinolone acetonide intravitreal implant
J. Sheppard, Q. Nguyen, D. Usner, T. Comstock
2012Clinical Ophthalmology15 citations Open access
Semantic Scholar
Iontophoretic Dexamethasone Phosphate Compared to Topical Prednisolone Acetate 1% for Noninfectious Anterior Segment Uveitis.
J. Sheppard, Sunir J. Garg, C. Lievens, Lisa A. Brandano +4 more
2019American journal of ophthalmology-glaucoma14 citations
Semantic Scholar
Phase 3 Efficacy (Worse-Eye Analysis) and Long-Term Safety Evaluation of OTX-101 in Patients with Keratoconjunctivitis Sicca
J. Sheppard, M. Bergmann, B. Schechter, J. Luchs +2 more
2021Clinical Ophthalmology12 citations Open access
Semantic Scholar
Management of repository corticotropin injection therapy for non-infectious uveitis: a Delphi study
Q. Nguyen, Stephen D. Anesi, Saradha Chexal, David S. Chu +9 more
2021Acta ophthalmologica11 citations Open access
Semantic Scholar
An Evaluation of Staphylococci from Ocular Surface Infections Treated Empirically with Topical Besifloxacin: Antibiotic Resistance, Molecular Characteristics, and Clinical Outcomes
B. Schechter, J. Sheppard, Christine M. Sanfilippo, H. DeCory +1 more
2019Ophthalmology and Therapy11 citations Open access
Semantic Scholar
Does Dry Eye Disease Severity Impact Efficacy of Varenicline Solution Nasal Spray on Sign and Symptom Treatment Outcomes?
J. Sheppard, L. O'dell, P. Karpecki, M. Raizman +6 more
2022Optometry and Vision Science10 citations Open access
Semantic Scholar
Reproxalap Improves Signs and Symptoms of Allergic Conjunctivitis in an Allergen Chamber: A Real-World Model of Allergen Exposure
D. Clark, P. Karpecki, A. Salapatek, J. Sheppard +1 more
2022Clinical Ophthalmology9 citations Open access
Semantic Scholar

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